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The map label for this gene is rnd [H]

Identifier: 221229981

GI number: 221229981

Start: 1205287

End: 1206576

Strand: Reverse

Name: rnd [H]

Synonym: MLBr_01040

Alternate gene names: 221229981

Gene position: 1206576-1205287 (Counterclockwise)

Preceding gene: 221229982

Following gene: 221229979

Centisome position: 36.92

GC content: 64.5

Gene sequence:

>1290_bases
ATGCGCGAACCGGCGGACGATCAGCCGGGCGGCACCGAACCCGACCCCACCCCGCTGCACTACCCGGCCGGCGGGATACC
GAACCTATCCGTAACCCCGAGCGAGATCGCGGCGGCCGCAGAACGCCTGGACCAAGGGTACGGCCCGTTTGCGGTAGACA
CCGAGCGGGCGTCGGGTTTTCGCTATTCCAACAGGGCTTACCTGATTCAGATCCGACGAGCGAACGCCGGCACCGTCCTC
ATCGACCCGGTCAGCCACGGCAATGATCCGCTGACCGCGCTGCGACCCGTCGCCGAGGTGATCAGCAAAGACGAATGGAT
CCTGCATTCGGCTGATCAGGATCTGCCGTGTCTGGCCGAAGTCGGCATGCGGCCGCCAGCGTTGTATGACACCGAACTTG
CCGGACGCCTGGCCGGATTTGACAGGGTGAACCTCGCAACAATGGTTCAGCGGCTGCTGGGTTTCGAGTTGGCCAAAGGC
CACGGTGCTGCCGATTGGTCGAAACGCCCGCTGCCTTCGGACTGGCTCAACTATGCGGCTCTAGACGTGGAGCTGCTGAT
CGAACTGCGCACGGCAATCTCGAAGGTGCTGGCCGAGCAAGACAAAACTGATTGGGCAACGCAGGAATTCAACTACCTGC
GGACCTATGCAACTAGGGGGGCCACCACCGAGACTATCCCACCCACCCGTCGGGACCGCTGGCGACGCACGTCAGGCATC
CGTCGGGTGCGCGACCGGCGAGCCCTGGCCGCCGTTCGCGAATTGTGGGCAACGCGCGACCACATTGCCCAACGTCGCGA
TATCGCACCACGTCGCATCCTGCCTGATACCGCCATCATCGACGCAGCCATAGCCGACCCCAAGACGATCGACGAGCTGA
TCGCAATGCCGGTTTTCGGCGGGGCCAATCAGCGTCGCAGCGCTGCGATGTGGTTGGCAGCGCTGGAAACGGCACGACAG
AGCCAAGACCTACCGGACGAAGCCGAGCCGTCCAACGTGCCACCACCGCCCGGGCGGTGGGCCCGGCGCAAACCAGATGC
CGCTGCACGGCTGGAGGCGGCCAGAGCGGCACTGGCGACGGTGTCGCAGCGGGTTGGGGTACCGACGGAAAATCTCGTCT
CGCCTGAACTGGTGCGACGACTGTGCTGGGACTGGGAGGTTCTGCCGGAAAGCTCGGTCGACCCGGTCAATGCAGTCGAG
GAATATTTGCGTGTCGGCCAAGCGCGAGCGTGGCAGCGAGAACTCGTGGTGACCATTCTGGCCTCGGCGGTGAAGTCGTC
GGCTGGCTAA

Upstream 100 bases:

>100_bases
GTCGGCGTCCACGTCAAAGCATTCTGCGAGGTGCTGGAACACGCCGCAGGACTGCCGCCGGCCGGAGTTATCGACCTGGG
CTCGCGCTCACGCTCCTGAT

Downstream 100 bases:

>100_bases
CGCTCATGTGTGAGCGTCGTACGGTGGCGTTTCCACCACCACATCGATCCTCACAGCCGCAGCACAACAAATGGGACAGG
ATCTCGCAAGTCCATTGCAA

Product: hypothetical protein

Products: NA

Alternate protein names: RNase D [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MREPADDQPGGTEPDPTPLHYPAGGIPNLSVTPSEIAAAAERLDQGYGPFAVDTERASGFRYSNRAYLIQIRRANAGTVL
IDPVSHGNDPLTALRPVAEVISKDEWILHSADQDLPCLAEVGMRPPALYDTELAGRLAGFDRVNLATMVQRLLGFELAKG
HGAADWSKRPLPSDWLNYAALDVELLIELRTAISKVLAEQDKTDWATQEFNYLRTYATRGATTETIPPTRRDRWRRTSGI
RRVRDRRALAAVRELWATRDHIAQRRDIAPRRILPDTAIIDAAIADPKTIDELIAMPVFGGANQRRSAAMWLAALETARQ
SQDLPDEAEPSNVPPPPGRWARRKPDAAARLEAARAALATVSQRVGVPTENLVSPELVRRLCWDWEVLPESSVDPVNAVE
EYLRVGQARAWQRELVVTILASAVKSSAG

Sequences:

>Translated_429_residues
MREPADDQPGGTEPDPTPLHYPAGGIPNLSVTPSEIAAAAERLDQGYGPFAVDTERASGFRYSNRAYLIQIRRANAGTVL
IDPVSHGNDPLTALRPVAEVISKDEWILHSADQDLPCLAEVGMRPPALYDTELAGRLAGFDRVNLATMVQRLLGFELAKG
HGAADWSKRPLPSDWLNYAALDVELLIELRTAISKVLAEQDKTDWATQEFNYLRTYATRGATTETIPPTRRDRWRRTSGI
RRVRDRRALAAVRELWATRDHIAQRRDIAPRRILPDTAIIDAAIADPKTIDELIAMPVFGGANQRRSAAMWLAALETARQ
SQDLPDEAEPSNVPPPPGRWARRKPDAAARLEAARAALATVSQRVGVPTENLVSPELVRRLCWDWEVLPESSVDPVNAVE
EYLRVGQARAWQRELVVTILASAVKSSAG
>Mature_429_residues
MREPADDQPGGTEPDPTPLHYPAGGIPNLSVTPSEIAAAAERLDQGYGPFAVDTERASGFRYSNRAYLIQIRRANAGTVL
IDPVSHGNDPLTALRPVAEVISKDEWILHSADQDLPCLAEVGMRPPALYDTELAGRLAGFDRVNLATMVQRLLGFELAKG
HGAADWSKRPLPSDWLNYAALDVELLIELRTAISKVLAEQDKTDWATQEFNYLRTYATRGATTETIPPTRRDRWRRTSGI
RRVRDRRALAAVRELWATRDHIAQRRDIAPRRILPDTAIIDAAIADPKTIDELIAMPVFGGANQRRSAAMWLAALETARQ
SQDLPDEAEPSNVPPPPGRWARRKPDAAARLEAARAALATVSQRVGVPTENLVSPELVRRLCWDWEVLPESSVDPVNAVE
EYLRVGQARAWQRELVVTILASAVKSSAG

Specific function: Cleaves multimeric tRNA precursor at the spacer region. Contribute to the 3' maturation of several stable RNAs [H]

COG id: COG0349

COG function: function code J; Ribonuclease D

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Escherichia coli, GI1788105, Length=356, Percent_Identity=26.123595505618, Blast_Score=72, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6324574, Length=236, Percent_Identity=25.4237288135593, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002562
- InterPro:   IPR002121
- InterPro:   IPR010997
- InterPro:   IPR006292
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01612 3_5_exonuc; PF00570 HRDC [H]

EC number: =3.1.13.5 [H]

Molecular weight: Translated: 47349; Mature: 47349

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREPADDQPGGTEPDPTPLHYPAGGIPNLSVTPSEIAAAAERLDQGYGPFAVDTERASGF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCC
RYSNRAYLIQIRRANAGTVLIDPVSHGNDPLTALRPVAEVISKDEWILHSADQDLPCLAE
EECCCEEEEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCHHHH
VGMRPPALYDTELAGRLAGFDRVNLATMVQRLLGFELAKGHGAADWSKRPLPSDWLNYAA
CCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
LDVELLIELRTAISKVLAEQDKTDWATQEFNYLRTYATRGATTETIPPTRRDRWRRTSGI
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RRVRDRRALAAVRELWATRDHIAQRRDIAPRRILPDTAIIDAAIADPKTIDELIAMPVFG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHCCHHHHHHHHHHCCCC
GANQRRSAAMWLAALETARQSQDLPDEAEPSNVPPPPGRWARRKPDAAARLEAARAALAT
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VSQRVGVPTENLVSPELVRRLCWDWEVLPESSVDPVNAVEEYLRVGQARAWQRELVVTIL
HHHHCCCCHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ASAVKSSAG
HHHHHHCCC
>Mature Secondary Structure
MREPADDQPGGTEPDPTPLHYPAGGIPNLSVTPSEIAAAAERLDQGYGPFAVDTERASGF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCC
RYSNRAYLIQIRRANAGTVLIDPVSHGNDPLTALRPVAEVISKDEWILHSADQDLPCLAE
EECCCEEEEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCHHHH
VGMRPPALYDTELAGRLAGFDRVNLATMVQRLLGFELAKGHGAADWSKRPLPSDWLNYAA
CCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
LDVELLIELRTAISKVLAEQDKTDWATQEFNYLRTYATRGATTETIPPTRRDRWRRTSGI
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RRVRDRRALAAVRELWATRDHIAQRRDIAPRRILPDTAIIDAAIADPKTIDELIAMPVFG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHCCHHHHHHHHHHCCCC
GANQRRSAAMWLAALETARQSQDLPDEAEPSNVPPPPGRWARRKPDAAARLEAARAALAT
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VSQRVGVPTENLVSPELVRRLCWDWEVLPESSVDPVNAVEEYLRVGQARAWQRELVVTIL
HHHHCCCCHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ASAVKSSAG
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3041371; 9097040; 9278503; 8107670 [H]