Click here to switch to the map view.

The map label for this gene is ppgK

Identifier: 221229970

GI number: 221229970

Start: 1190960

End: 1191934

Strand: Reverse

Name: ppgK

Synonym: MLBr_01023

Alternate gene names: 221229970

Gene position: 1191934-1190960 (Counterclockwise)

Preceding gene: 221229972

Following gene: 221229969

Centisome position: 36.47

GC content: 59.49

Gene sequence:

>975_bases
GTGATTCGGCTACGCAGCGCAGCTGCTCGGGATCGTTGTCAGGTACTGTCACTGGCCTATCGCATCACAGTCGCCGGCAG
ATGCCAGACAGTCAGCCCGCATCATCGCCAGGCTAAAGTAAGCGAACAACCAAGTCTCGCCAAGGAGATTGCTATAACGA
GCACCGACGCGACCGCAGATACGCCCAGAACCTCTCCGCCTAGCGACACCGCCGGTACGACATCGCGGCACCGCGGGTTC
GGCATCGATATCGGCGGCAGCAGCATCAAGGGTGGCATAGTCGACCTCGACATCGGGCAACTGATTGGTGACCGCATCAA
ACTGCTCACCCCTCAACCGGCTACCCCATTGGCAGTCGCCAAGACCATTGCCGAGGTCGTCAACGCATTCGGATGGACTG
CTCCCCTGGGAGTGACCTATCCCGGCGTCGTCACCCAGGGCGTCGTCCGAACGGCTGCCAACGTGGACGACTCCTGGATT
GGAACCAATGCCCGCGACATTATCAGCGCTGAGCTGAACAGCCAGGAAGTCACCATTCTCAACGACGCGGATGCTGCTGG
GCTTGCTGAAGGGCGCTATGGAGCGGGCAAAAACAACTCTGGCTTGATTGTGCTACTCACCTTCGGCACCGGGATCGGGT
CAGCAGTCATCCACAACGGGAAACTGATTCCTAACACCGAGTTCGGGCATCTCGAGGTCGACGGTAAAGAGGCCGAACAA
CGAGCGGCATCGTCCGTCAAAGACAAGTACAAATGGAGCTACCGAACATGGGCCAAGCAGGTAACGAGGGTGCTGGTCGC
CATCGAAAACGCGATGTGTCCTGACCTGTTCATTGCCGGCGGCGGCATCAGCCGCAAGGCCGATAGATGGATACCACTGC
TTGAAAACCGCACCCCGATGGTGGCCGCAGCCCTGCAGAATACGGCCGGCATAGTCGGCGCTGCCATGGCTTCTACCGCA
GATGTGACGCACTGA

Upstream 100 bases:

>100_bases
GTACTCTTCGCCCGTACCGCGCCGCCGCCTGCGGCGCCCAGGTCAGTACCAAACACCTCAGCTCGGCGACATCGCACGAA
CGCGGCGGCCTCAGTGGCCA

Downstream 100 bases:

>100_bases
ATTTTGCCCGGTGGAACAGTCCAGGCGCGTGCCACCGTTACAATGGTTATCGGCGGTCGCCCGACCGATAGCGCGAGTAC
TCACGCTGATATCAACGCCG

Product: polyphosphate glucokinase

Products: NA

Alternate protein names: Polyphosphate--glucose phosphotransferase

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MIRLRSAAARDRCQVLSLAYRITVAGRCQTVSPHHRQAKVSEQPSLAKEIAITSTDATADTPRTSPPSDTAGTTSRHRGF
GIDIGGSSIKGGIVDLDIGQLIGDRIKLLTPQPATPLAVAKTIAEVVNAFGWTAPLGVTYPGVVTQGVVRTAANVDDSWI
GTNARDIISAELNSQEVTILNDADAAGLAEGRYGAGKNNSGLIVLLTFGTGIGSAVIHNGKLIPNTEFGHLEVDGKEAEQ
RAASSVKDKYKWSYRTWAKQVTRVLVAIENAMCPDLFIAGGGISRKADRWIPLLENRTPMVAAALQNTAGIVGAAMASTA
DVTH

Sequences:

>Translated_324_residues
MIRLRSAAARDRCQVLSLAYRITVAGRCQTVSPHHRQAKVSEQPSLAKEIAITSTDATADTPRTSPPSDTAGTTSRHRGF
GIDIGGSSIKGGIVDLDIGQLIGDRIKLLTPQPATPLAVAKTIAEVVNAFGWTAPLGVTYPGVVTQGVVRTAANVDDSWI
GTNARDIISAELNSQEVTILNDADAAGLAEGRYGAGKNNSGLIVLLTFGTGIGSAVIHNGKLIPNTEFGHLEVDGKEAEQ
RAASSVKDKYKWSYRTWAKQVTRVLVAIENAMCPDLFIAGGGISRKADRWIPLLENRTPMVAAALQNTAGIVGAAMASTA
DVTH
>Mature_324_residues
MIRLRSAAARDRCQVLSLAYRITVAGRCQTVSPHHRQAKVSEQPSLAKEIAITSTDATADTPRTSPPSDTAGTTSRHRGF
GIDIGGSSIKGGIVDLDIGQLIGDRIKLLTPQPATPLAVAKTIAEVVNAFGWTAPLGVTYPGVVTQGVVRTAANVDDSWI
GTNARDIISAELNSQEVTILNDADAAGLAEGRYGAGKNNSGLIVLLTFGTGIGSAVIHNGKLIPNTEFGHLEVDGKEAEQ
RAASSVKDKYKWSYRTWAKQVTRVLVAIENAMCPDLFIAGGGISRKADRWIPLLENRTPMVAAALQNTAGIVGAAMASTA
DVTH

Specific function: Catalyzes the phosphorylation of glucose using polyphosphate or ATP as the phosphoryl donor

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): PPGK_MYCLE (Q49988)

Other databases:

- EMBL:   U15181
- EMBL:   AL583920
- PIR:   A87037
- RefSeq:   NP_301756.1
- ProteinModelPortal:   Q49988
- SMR:   Q49988
- EnsemblBacteria:   EBMYCT00000028678
- GeneID:   910085
- GenomeReviews:   AL450380_GR
- KEGG:   mle:ML1023
- NMPDR:   fig|272631.1.peg.628
- Leproma:   ML1023
- GeneTree:   EBGT00050000016959
- HOGENOM:   HBG730260
- OMA:   AANVDKG
- ProtClustDB:   CLSK2460514
- BioCyc:   MLEP272631:ML1023-MONOMER
- BRENDA:   2.7.1.63
- GO:   GO:0005737
- InterPro:   IPR000600

Pfam domain/function: PF00480 ROK

EC number: =2.7.1.63

Molecular weight: Translated: 34102; Mature: 34102

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRLRSAAARDRCQVLSLAYRITVAGRCQTVSPHHRQAKVSEQPSLAKEIAITSTDATAD
CEEECCHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHCCCCCCCCHHHHEEEECCCCCCC
TPRTSPPSDTAGTTSRHRGFGIDIGGSSIKGGIVDLDIGQLIGDRIKLLTPQPATPLAVA
CCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEEEHHHHHCCCEEEECCCCCCHHHHH
KTIAEVVNAFGWTAPLGVTYPGVVTQGVVRTAANVDDSWIGTNARDIISAELNSQEVTIL
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHEEECCCCCEEEEE
NDADAAGLAEGRYGAGKNNSGLIVLLTFGTGIGSAVIHNGKLIPNTEFGHLEVDGKEAEQ
ECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHEECCEECCCCCCCEEEECCHHHHH
RAASSVKDKYKWSYRTWAKQVTRVLVAIENAMCPDLFIAGGGISRKADRWIPLLENRTPM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHCCCCCH
VAAALQNTAGIVGAAMASTADVTH
HHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MIRLRSAAARDRCQVLSLAYRITVAGRCQTVSPHHRQAKVSEQPSLAKEIAITSTDATAD
CEEECCHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHCCCCCCCCHHHHEEEECCCCCCC
TPRTSPPSDTAGTTSRHRGFGIDIGGSSIKGGIVDLDIGQLIGDRIKLLTPQPATPLAVA
CCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEEEHHHHHCCCEEEECCCCCCHHHHH
KTIAEVVNAFGWTAPLGVTYPGVVTQGVVRTAANVDDSWIGTNARDIISAELNSQEVTIL
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHEEECCCCCEEEEE
NDADAAGLAEGRYGAGKNNSGLIVLLTFGTGIGSAVIHNGKLIPNTEFGHLEVDGKEAEQ
ECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHEECCEECCCCCCCEEEECCHHHHH
RAASSVKDKYKWSYRTWAKQVTRVLVAIENAMCPDLFIAGGGISRKADRWIPLLENRTPM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHCCCCCH
VAAALQNTAGIVGAAMASTADVTH
HHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002