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The map label for this gene is ribF [H]

Identifier: 221229855

GI number: 221229855

Start: 1012178

End: 1013173

Strand: Direct

Name: ribF [H]

Synonym: MLBr_00852

Alternate gene names: 221229855

Gene position: 1012178-1013173 (Clockwise)

Preceding gene: 221229854

Following gene: 221229856

Centisome position: 30.97

GC content: 62.15

Gene sequence:

>996_bases
ATGGGGAGCCGTAGGCTTGCGATCGTGCAGCGGTGGCGGGGACAAGACGAGATCCCCACGGATTGGGGCAGATGCGTGCT
TACTATCGGGGTGTTCGATGGTGTGCACCGCGGGCACACCGAGCTTATCGCACACACGGTGCAAACTGGCCGCGCACGCA
ACGTGCCTACCGTGTTGATGACGTTCGACCCGCACCCGATGGAAGTGGTCTATCCAGGCAGCCACCCGGCGCAGCTGACC
ACGTTGACCCGACGAGCTGAACTCATCGAGGAGTTGGGCATCGACGTGTTCCTGGTGATGCCGTTCACGACCGATTTCAT
GAAACTCACCCCGGACCGCTACGTCCACGAGTTGCTGGTTGAACACCTGCACGTGGTGGAGGTCGTGGTGGGGGAGAACT
TCACCTTCGGCAAGAAAGCGGCCGGCAACGTCATCATGTTGCGTCGGGCCGGGCAGCGGTTTGGGTTTGCGGTCGGGTCG
ATGTCACTGTTGTCCGAACATCGCGGTAATGAGACCGTGGCGTTCTCATCGACCTACATCCGGTCCTGTGTGGACGCCGG
TGACATGATGGCGGCGACCGAAGCGCTGGGCCGCCCACACCGCGTCGAGGGGATGGTGGTCCGCGGCCAAGGCCGAGGCA
CTGAGCTTGGCTTTCCAACCGCGAATGTGGCTTCGCCGATGTATTCGGCCACCCCAGCCGACGGTGTCTATGCCGCGTGG
TTCACCGTGCTTGGGCACGGTCCGGTGACTGGTACCGTGGTCCCAGGTGAATGCTATCAGGCCGCAGTGTCTGTCGGGAC
CAATCCGACTTTTTCCGGACGCACCCGCACCGTAGAGGCGTTCGTTCTCGACGCCGTCGCCGACCTGTATGGACAGCATG
TAGCGCTGGACTTCGTTGGGCGCATTCGTGGGCAACGAAAATTTGACTCGGTGGCCGATTTAGTCGCCGAGATGGAGAAG
GACATTGACCGGGCGCGGGCCCTGCTGGCTGATTGA

Upstream 100 bases:

>100_bases
GCAACCTGGGGTAGGGAACTGACTGCTTGGGCGTCCCGCCCGGCAACCCTTGGTACAGCACGGATTAACTCGCAATTTGG
ATCTTGCACACCGGCGGATC

Downstream 100 bases:

>100_bases
CTGGCCTTAGTTCGGCGAGCTGCTAAACTGCCGGACGACATCGGTGCGTGCTGCGGTTCGCGGTGGCCGCGCAGCAGTAC
TGTCCATGATCGCGGACCAA

Product: bifunctional riboflavin kinase/FMN adenylyltransferase

Products: NA

Alternate protein names: Riboflavin kinase; Flavokinase; FMN adenylyltransferase; FAD pyrophosphorylase; FAD synthase [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MGSRRLAIVQRWRGQDEIPTDWGRCVLTIGVFDGVHRGHTELIAHTVQTGRARNVPTVLMTFDPHPMEVVYPGSHPAQLT
TLTRRAELIEELGIDVFLVMPFTTDFMKLTPDRYVHELLVEHLHVVEVVVGENFTFGKKAAGNVIMLRRAGQRFGFAVGS
MSLLSEHRGNETVAFSSTYIRSCVDAGDMMAATEALGRPHRVEGMVVRGQGRGTELGFPTANVASPMYSATPADGVYAAW
FTVLGHGPVTGTVVPGECYQAAVSVGTNPTFSGRTRTVEAFVLDAVADLYGQHVALDFVGRIRGQRKFDSVADLVAEMEK
DIDRARALLAD

Sequences:

>Translated_331_residues
MGSRRLAIVQRWRGQDEIPTDWGRCVLTIGVFDGVHRGHTELIAHTVQTGRARNVPTVLMTFDPHPMEVVYPGSHPAQLT
TLTRRAELIEELGIDVFLVMPFTTDFMKLTPDRYVHELLVEHLHVVEVVVGENFTFGKKAAGNVIMLRRAGQRFGFAVGS
MSLLSEHRGNETVAFSSTYIRSCVDAGDMMAATEALGRPHRVEGMVVRGQGRGTELGFPTANVASPMYSATPADGVYAAW
FTVLGHGPVTGTVVPGECYQAAVSVGTNPTFSGRTRTVEAFVLDAVADLYGQHVALDFVGRIRGQRKFDSVADLVAEMEK
DIDRARALLAD
>Mature_330_residues
GSRRLAIVQRWRGQDEIPTDWGRCVLTIGVFDGVHRGHTELIAHTVQTGRARNVPTVLMTFDPHPMEVVYPGSHPAQLTT
LTRRAELIEELGIDVFLVMPFTTDFMKLTPDRYVHELLVEHLHVVEVVVGENFTFGKKAAGNVIMLRRAGQRFGFAVGSM
SLLSEHRGNETVAFSSTYIRSCVDAGDMMAATEALGRPHRVEGMVVRGQGRGTELGFPTANVASPMYSATPADGVYAAWF
TVLGHGPVTGTVVPGECYQAAVSVGTNPTFSGRTRTVEAFVLDAVADLYGQHVALDFVGRIRGQRKFDSVADLVAEMEKD
IDRARALLAD

Specific function: Unknown

COG id: COG0196

COG function: function code H; FAD synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribF family [H]

Homologues:

Organism=Homo sapiens, GI269973877, Length=136, Percent_Identity=31.6176470588235, Blast_Score=78, Evalue=9e-15,
Organism=Escherichia coli, GI1786208, Length=303, Percent_Identity=36.3036303630363, Blast_Score=195, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI17541882, Length=131, Percent_Identity=33.587786259542, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24644927, Length=131, Percent_Identity=37.4045801526718, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015864
- InterPro:   IPR015865
- InterPro:   IPR002606
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06574 FAD_syn; PF01687 Flavokinase [H]

EC number: =2.7.1.26; =2.7.7.2 [H]

Molecular weight: Translated: 36155; Mature: 36024

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSRRLAIVQRWRGQDEIPTDWGRCVLTIGVFDGVHRGHTELIAHTVQTGRARNVPTVLM
CCCCHHHHHHHHCCCCCCCCCCCCEEEEEEHHCCCCCCHHHHHHHHHHCCCCCCCCEEEE
TFDPHPMEVVYPGSHPAQLTTLTRRAELIEELGIDVFLVMPFTTDFMKLTPDRYVHELLV
EECCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHCCHHHHHHHHHH
EHLHVVEVVVGENFTFGKKAAGNVIMLRRAGQRFGFAVGSMSLLSEHRGNETVAFSSTYI
HHHHHHHHEECCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEHHHHH
RSCVDAGDMMAATEALGRPHRVEGMVVRGQGRGTELGFPTANVASPMYSATPADGVYAAW
HHHHCCCHHHHHHHHHCCCCEECEEEEECCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHH
FTVLGHGPVTGTVVPGECYQAAVSVGTNPTFSGRTRTVEAFVLDAVADLYGQHVALDFVG
HHHHCCCCCEEEEECCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHH
RIRGQRKFDSVADLVAEMEKDIDRARALLAD
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GSRRLAIVQRWRGQDEIPTDWGRCVLTIGVFDGVHRGHTELIAHTVQTGRARNVPTVLM
CCCHHHHHHHHCCCCCCCCCCCCEEEEEEHHCCCCCCHHHHHHHHHHCCCCCCCCEEEE
TFDPHPMEVVYPGSHPAQLTTLTRRAELIEELGIDVFLVMPFTTDFMKLTPDRYVHELLV
EECCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHCCHHHHHHHHHH
EHLHVVEVVVGENFTFGKKAAGNVIMLRRAGQRFGFAVGSMSLLSEHRGNETVAFSSTYI
HHHHHHHHEECCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEHHHHH
RSCVDAGDMMAATEALGRPHRVEGMVVRGQGRGTELGFPTANVASPMYSATPADGVYAAW
HHHHCCCHHHHHHHHHCCCCEECEEEEECCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHH
FTVLGHGPVTGTVVPGECYQAAVSVGTNPTFSGRTRTVEAFVLDAVADLYGQHVALDFVG
HHHHCCCCCEEEEECCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHH
RIRGQRKFDSVADLVAEMEKDIDRARALLAD
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7772835; 3023344 [H]