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The map label for this gene is ubiB [C]

Identifier: 221229744

GI number: 221229744

Start: 772077

End: 773498

Strand: Reverse

Name: ubiB [C]

Synonym: MLBr_00640

Alternate gene names: 221229744

Gene position: 773498-772077 (Counterclockwise)

Preceding gene: 221229745

Following gene: 221229724

Centisome position: 23.67

GC content: 58.02

Gene sequence:

>1422_bases
ATGATGCGGGTGAAAGCCCGAATGAATAATGAATGTAGCCGTTTGATCATTGATTGCCATATCACGTCCATGGCACGCTT
CACCGTCATGGATGATAGACGTGTGGCAGACATCAAACGTGGTCAGGCTGCGCGCAACGCGAAGCTAGCTAGCATTCCGG
TCGGCCTTGCCGGGCGGGCGGTGCTCGGGCTCGGGAAACGACTGACTGGCAAGTCGAAAGACGAGGTTAACACCAAGCTG
ATAGAGAAGACCGCCCACCAGTTGTTCAGTGTCCTGGGCGAGCTCAAGGGCGGGGCAATGAAGGTCGGCCAGGCATTGTC
TGTGATGGAAGCCGCGATTCCTGAAGAGTACGGCGAGCCCTACCGCGAAGCCCTGACCAAGCTGCAAAAGGACGCCCCGC
CGTTGCCGGTCAACAAGGTGCATCGGGTGCTCGACGCCCAGTTAGGCACCAAGTGGCGGGACCGGTTCAGCTCGTTCAAC
GACACCCCGGTGGCCTCGGCCAGCATCGGCCAGGTGCATAAAGCGGTATGGTCCTATGGCCGCGAAGTGGCGGTCAAAAT
CCAGTATCCGGGTGCTGATGAGGCGTTGCGCGCCGATCTCAAGACCATGCAGCGGATGGTTGGGATACTCAAACAGCTCT
CTCCCGGTGCTGACATCCAAGGTGTGGTAGACGAATTAGTCGAACGCACCGAGATGGAACTAGATTATCGGTTGGAGGCT
GACAACCAACGTGCTTTCGCCAAGGCGTATCAGGGCGACCCGCGCTTTGTGGTGCCAAACGTGGTGGCAAGCGCACCGAA
AGTGATAATCCAGGAGTGGATCGATGGTGTTCCGATGGCCGAAATCATCCGTAACGGAACCGCCCAACAACGTGACCGTA
TGGGAAAACTGCTACTCGAACTCACCTTCGATTCGCCACGCCGATTGGAAATGCTGCACGGCGACGCTCACCCAGGCAAT
TTCATGCTGCTGTCCGACGGCCGGATGGGCGTCATCGACTTCGGCGCTATCGCGCCACTGCCTGGTGGTTTCCCGGTAGA
GCTGGGAATGAGCATCCGATTGGCCCGGGACAAGAACTACAACCTCTTGCTGCAGACGATGGAGAAGGCCGGCTTAATCC
AAAAAGGCCGACAGGTGTCTGTGCGCGACATTGACGAGATGATGCACCAGTACGTAGAACCGATCAAAGTCGAGGTTTTC
CACTACACACGTAAATGGCTGCAACAGATAAGCCTAGACCGATCGGTGTCGCACATCAAGACGGCACGCCAGTTGGATCT
GCCGGCTACACTGGCCCTGCCTATGCGGGTGATCGCGTCGGTGGGCGCGATCCTCTGCCAACTCGACGCGCATGTGCCGA
CCAAGGCTCTGACCGAGAAGTTGGTTCCCGGCTTCGCCGAGCCCGATACTGCCATCGTCTAA

Upstream 100 bases:

>100_bases
GTTTGCTTTACTGCCATGGCTTTTCGGTACCACCCTTCGAACATGCGTTTCAATGAACCACAAGATTGAACCTGCACGGA
GAAAATTGGCTCGACGCTGG

Downstream 100 bases:

>100_bases
CGCCCCAAAAGTGCCACTACTGAGGCCGTCTCTTCAAGGAACAATTCGACAATTGCACTTTCGTGACCTTGTTTCTCTAA
ACAACGACGACATCGTTGCA

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MMRVKARMNNECSRLIIDCHITSMARFTVMDDRRVADIKRGQAARNAKLASIPVGLAGRAVLGLGKRLTGKSKDEVNTKL
IEKTAHQLFSVLGELKGGAMKVGQALSVMEAAIPEEYGEPYREALTKLQKDAPPLPVNKVHRVLDAQLGTKWRDRFSSFN
DTPVASASIGQVHKAVWSYGREVAVKIQYPGADEALRADLKTMQRMVGILKQLSPGADIQGVVDELVERTEMELDYRLEA
DNQRAFAKAYQGDPRFVVPNVVASAPKVIIQEWIDGVPMAEIIRNGTAQQRDRMGKLLLELTFDSPRRLEMLHGDAHPGN
FMLLSDGRMGVIDFGAIAPLPGGFPVELGMSIRLARDKNYNLLLQTMEKAGLIQKGRQVSVRDIDEMMHQYVEPIKVEVF
HYTRKWLQQISLDRSVSHIKTARQLDLPATLALPMRVIASVGAILCQLDAHVPTKALTEKLVPGFAEPDTAIV

Sequences:

>Translated_473_residues
MMRVKARMNNECSRLIIDCHITSMARFTVMDDRRVADIKRGQAARNAKLASIPVGLAGRAVLGLGKRLTGKSKDEVNTKL
IEKTAHQLFSVLGELKGGAMKVGQALSVMEAAIPEEYGEPYREALTKLQKDAPPLPVNKVHRVLDAQLGTKWRDRFSSFN
DTPVASASIGQVHKAVWSYGREVAVKIQYPGADEALRADLKTMQRMVGILKQLSPGADIQGVVDELVERTEMELDYRLEA
DNQRAFAKAYQGDPRFVVPNVVASAPKVIIQEWIDGVPMAEIIRNGTAQQRDRMGKLLLELTFDSPRRLEMLHGDAHPGN
FMLLSDGRMGVIDFGAIAPLPGGFPVELGMSIRLARDKNYNLLLQTMEKAGLIQKGRQVSVRDIDEMMHQYVEPIKVEVF
HYTRKWLQQISLDRSVSHIKTARQLDLPATLALPMRVIASVGAILCQLDAHVPTKALTEKLVPGFAEPDTAIV
>Mature_473_residues
MMRVKARMNNECSRLIIDCHITSMARFTVMDDRRVADIKRGQAARNAKLASIPVGLAGRAVLGLGKRLTGKSKDEVNTKL
IEKTAHQLFSVLGELKGGAMKVGQALSVMEAAIPEEYGEPYREALTKLQKDAPPLPVNKVHRVLDAQLGTKWRDRFSSFN
DTPVASASIGQVHKAVWSYGREVAVKIQYPGADEALRADLKTMQRMVGILKQLSPGADIQGVVDELVERTEMELDYRLEA
DNQRAFAKAYQGDPRFVVPNVVASAPKVIIQEWIDGVPMAEIIRNGTAQQRDRMGKLLLELTFDSPRRLEMLHGDAHPGN
FMLLSDGRMGVIDFGAIAPLPGGFPVELGMSIRLARDKNYNLLLQTMEKAGLIQKGRQVSVRDIDEMMHQYVEPIKVEVF
HYTRKWLQQISLDRSVSHIKTARQLDLPATLALPMRVIASVGAILCQLDAHVPTKALTEKLVPGFAEPDTAIV

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI34147522, Length=328, Percent_Identity=28.0487804878049, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI27363457, Length=307, Percent_Identity=28.0130293159609, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI40254938, Length=265, Percent_Identity=29.811320754717, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI217416386, Length=245, Percent_Identity=28.9795918367347, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI217035081, Length=242, Percent_Identity=30.5785123966942, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI41393593, Length=258, Percent_Identity=25.968992248062, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI2367309, Length=245, Percent_Identity=27.3469387755102, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI32565180, Length=354, Percent_Identity=27.683615819209, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17559152, Length=320, Percent_Identity=27.8125, Blast_Score=104, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6321319, Length=321, Percent_Identity=25.5451713395639, Blast_Score=117, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6323282, Length=187, Percent_Identity=27.2727272727273, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI18859849, Length=324, Percent_Identity=28.0864197530864, Blast_Score=132, Evalue=6e-31,
Organism=Drosophila melanogaster, GI22024280, Length=271, Percent_Identity=29.520295202952, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24662575, Length=284, Percent_Identity=27.112676056338, Blast_Score=86, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 52440; Mature: 52440

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRVKARMNNECSRLIIDCHITSMARFTVMDDRRVADIKRGQAARNAKLASIPVGLAGRA
CCEECCCCCCCCCEEEEEEEEHHHHHEEEECCCHHHHHHHCCHHHCCEEEECCCCCCCHH
VLGLGKRLTGKSKDEVNTKLIEKTAHQLFSVLGELKGGAMKVGQALSVMEAAIPEEYGEP
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHCCH
YREALTKLQKDAPPLPVNKVHRVLDAQLGTKWRDRFSSFNDTPVASASIGQVHKAVWSYG
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCC
REVAVKIQYPGADEALRADLKTMQRMVGILKQLSPGADIQGVVDELVERTEMELDYRLEA
CEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEEECC
DNQRAFAKAYQGDPRFVVPNVVASAPKVIIQEWIDGVPMAEIIRNGTAQQRDRMGKLLLE
CCCHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHEEEE
LTFDSPRRLEMLHGDAHPGNFMLLSDGRMGVIDFGAIAPLPGGFPVELGMSIRLARDKNY
EECCCCHHHHHHCCCCCCCCEEEEECCCCCEEECCCCCCCCCCCCEEECCEEEEECCCCC
NLLLQTMEKAGLIQKGRQVSVRDIDEMMHQYVEPIKVEVFHYTRKWLQQISLDRSVSHIK
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TARQLDLPATLALPMRVIASVGAILCQLDAHVPTKALTEKLVPGFAEPDTAIV
HHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MMRVKARMNNECSRLIIDCHITSMARFTVMDDRRVADIKRGQAARNAKLASIPVGLAGRA
CCEECCCCCCCCCEEEEEEEEHHHHHEEEECCCHHHHHHHCCHHHCCEEEECCCCCCCHH
VLGLGKRLTGKSKDEVNTKLIEKTAHQLFSVLGELKGGAMKVGQALSVMEAAIPEEYGEP
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHCCH
YREALTKLQKDAPPLPVNKVHRVLDAQLGTKWRDRFSSFNDTPVASASIGQVHKAVWSYG
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCC
REVAVKIQYPGADEALRADLKTMQRMVGILKQLSPGADIQGVVDELVERTEMELDYRLEA
CEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEEECC
DNQRAFAKAYQGDPRFVVPNVVASAPKVIIQEWIDGVPMAEIIRNGTAQQRDRMGKLLLE
CCCHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHEEEE
LTFDSPRRLEMLHGDAHPGNFMLLSDGRMGVIDFGAIAPLPGGFPVELGMSIRLARDKNY
EECCCCHHHHHHCCCCCCCCEEEEECCCCCEEECCCCCCCCCCCCEEECCEEEEECCCCC
NLLLQTMEKAGLIQKGRQVSVRDIDEMMHQYVEPIKVEVFHYTRKWLQQISLDRSVSHIK
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TARQLDLPATLALPMRVIASVGAILCQLDAHVPTKALTEKLVPGFAEPDTAIV
HHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA