Click here to switch to the map view.

The map label for this gene is 221229725

Identifier: 221229725

GI number: 221229725

Start: 736559

End: 738244

Strand: Direct

Name: 221229725

Synonym: MLBr_00605

Alternate gene names: NA

Gene position: 736559-738244 (Clockwise)

Preceding gene: 221229723

Following gene: 221229726

Centisome position: 22.54

GC content: 59.43

Gene sequence:

>1686_bases
ATGTCTCAGGTGAGTCTTCCCAGCCAGCTCAAGGAGACTGGACCACGGTTGCAGTCTCGTTGCCGGTCCTCCGCCCGGTC
TGAGCGCATTTTCGGTGGGTACAACACCTCGGACATCTATTCAATGGCCTTTGACGAAATGTTCGATGTTCAAGGCAATG
TTCGTGGTCCGTACAAGGGCATCTACGCTGAGCTGGCGCCGTCGGATGCGTCCGAGCTGAAAGCTCGCGCCGAAGCGTTG
GCTCGCGCATTCATAGATCAGGGTATCACGTTTTCGCTGTCGGGTCAGGAGCGGCCCTTTCCGCTGGACTTGGTGCCGCG
TGTGATCTCGGCATCCGAGTGGAGCCGATTGGAGCGGGGTATCACCCAGCGCGTCAAGGCTCTTGAGATGTACCTAGACG
ACATCTATGGCGATCAGGAAATCCTGCGCGACGGCGTCATCCCGCGCCGCTTGATTACCTCGTGTGAGCACTTTCACCGC
CAGGCGGTTGGTATTATCCCACCCAACGGCGTGCGCATCCACGTCGCGGGCATCGACTTGATTCGCGATGACAGCGGCAA
TTTCCGGGTGCTCGAGGACAATCTTCGCTCGCCGTCCGGGGTGTCGTATGTGATGGAGAACCGGCGCACCATAGCGCGGG
TTTTCCCGAATCTTTTTGCCACCCATCGGGTGCGAGCGGTCGACGACTACGCCTCGCATTTGCTGAGGGCGCTGCGTAAC
TCGGCAGCCACCAATGAGGCAGACCCGACGGTGGTGGTGTTGACTCCGGGGGTGGCCAACGCGGCTTACTTCGAGCACTC
GTTACTAGCCCGCCAGATGGGTGTCGAGTTGGTCGAAGGACGTGATCTGTTCTGTCGCGACAACCAAGTATACATGTGTA
CCACCGAGGGGGAGCGCCAGGTCGATGTCATTTATCGGCGTATCGATGACGCTTTTCTAGACCCGTTGCAATTCCGTGCT
GATTCTGTACTGGGGGTGGCCGGATTGGTGAACGCTGCGCGCGCGGGCAACGTCGTCATCTCGAGTGCGATAGGAAACGG
TGTTGGCGACGACAAACTCGTGTACACCTACGTGCCTACCATGATGGAGTACTACTTACGGGAAAAGCCGTTGCTGGCGA
ATGTCGATACTTTGCGCTGCTGGCTGGATGACGAACGCCAAGAAGTGCTTGACCGGATCCACGACCTAGTTCTCAAGCCG
GTTGAAGGTTCCGGCGGTTACGGAATCGTTTTTGGTCCCGATGCCTCCGAGAAAGAGCTCGCTGCTGCCAGTAAAAAGAT
TCGCGACGATCCCCGAAGTTGGATCGCGCAACCAGTGATGGAACTCTCGACTGTGCCGACCCAGGTTGGTAGTACGCTGG
CGCCGCGTTATGTCGACCTGCGGCCGTTCGCAGTCAACGACGGCAACGACGTGTGGGTGCTGCCGGGTGGACTTACTCGT
GTTGCGCTGGTCGAAGGTTCGCGGGTGGTCAACTCCAGTCAGGGCGGTGGCTCCAAGGACACCTGGGTGCTGGCGCCGCA
TGCGTCGTATGGCGCACGTGAGCTGGGCGCCGCTGAAATCGTGTGTTCATTGCCGCAGTCGTCGCCCGACCCAGTGCCCG
ACGGATCGCCGCGACCAAAACAACAGCCGCAGCAAGCGCAAGCCGAGCAAGCGCAGCAACCGCAACAGCAGATAATGTTG
CCCTGA

Upstream 100 bases:

>100_bases
CTCTTCTACTCTACGGCGACAAACTTTTAGAGTACCAGTCGGCTACGCTTTCTCACAAAAGCACAACTTTGTGCTGCTGG
AACGGACAATTTGAGGCAGC

Downstream 100 bases:

>100_bases
TGCTTGCCCGTAACGCCGAGGCGCTCTATTGGATCGGTCGCTACGTCGAACGTGCCGACGACACCGCGCGCATTCTCGAC
GTCGTTGTGCACCAATTGTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 561; Mature: 560

Protein sequence:

>561_residues
MSQVSLPSQLKETGPRLQSRCRSSARSERIFGGYNTSDIYSMAFDEMFDVQGNVRGPYKGIYAELAPSDASELKARAEAL
ARAFIDQGITFSLSGQERPFPLDLVPRVISASEWSRLERGITQRVKALEMYLDDIYGDQEILRDGVIPRRLITSCEHFHR
QAVGIIPPNGVRIHVAGIDLIRDDSGNFRVLEDNLRSPSGVSYVMENRRTIARVFPNLFATHRVRAVDDYASHLLRALRN
SAATNEADPTVVVLTPGVANAAYFEHSLLARQMGVELVEGRDLFCRDNQVYMCTTEGERQVDVIYRRIDDAFLDPLQFRA
DSVLGVAGLVNAARAGNVVISSAIGNGVGDDKLVYTYVPTMMEYYLREKPLLANVDTLRCWLDDERQEVLDRIHDLVLKP
VEGSGGYGIVFGPDASEKELAAASKKIRDDPRSWIAQPVMELSTVPTQVGSTLAPRYVDLRPFAVNDGNDVWVLPGGLTR
VALVEGSRVVNSSQGGGSKDTWVLAPHASYGARELGAAEIVCSLPQSSPDPVPDGSPRPKQQPQQAQAEQAQQPQQQIML
P

Sequences:

>Translated_561_residues
MSQVSLPSQLKETGPRLQSRCRSSARSERIFGGYNTSDIYSMAFDEMFDVQGNVRGPYKGIYAELAPSDASELKARAEAL
ARAFIDQGITFSLSGQERPFPLDLVPRVISASEWSRLERGITQRVKALEMYLDDIYGDQEILRDGVIPRRLITSCEHFHR
QAVGIIPPNGVRIHVAGIDLIRDDSGNFRVLEDNLRSPSGVSYVMENRRTIARVFPNLFATHRVRAVDDYASHLLRALRN
SAATNEADPTVVVLTPGVANAAYFEHSLLARQMGVELVEGRDLFCRDNQVYMCTTEGERQVDVIYRRIDDAFLDPLQFRA
DSVLGVAGLVNAARAGNVVISSAIGNGVGDDKLVYTYVPTMMEYYLREKPLLANVDTLRCWLDDERQEVLDRIHDLVLKP
VEGSGGYGIVFGPDASEKELAAASKKIRDDPRSWIAQPVMELSTVPTQVGSTLAPRYVDLRPFAVNDGNDVWVLPGGLTR
VALVEGSRVVNSSQGGGSKDTWVLAPHASYGARELGAAEIVCSLPQSSPDPVPDGSPRPKQQPQQAQAEQAQQPQQQIML
P
>Mature_560_residues
SQVSLPSQLKETGPRLQSRCRSSARSERIFGGYNTSDIYSMAFDEMFDVQGNVRGPYKGIYAELAPSDASELKARAEALA
RAFIDQGITFSLSGQERPFPLDLVPRVISASEWSRLERGITQRVKALEMYLDDIYGDQEILRDGVIPRRLITSCEHFHRQ
AVGIIPPNGVRIHVAGIDLIRDDSGNFRVLEDNLRSPSGVSYVMENRRTIARVFPNLFATHRVRAVDDYASHLLRALRNS
AATNEADPTVVVLTPGVANAAYFEHSLLARQMGVELVEGRDLFCRDNQVYMCTTEGERQVDVIYRRIDDAFLDPLQFRAD
SVLGVAGLVNAARAGNVVISSAIGNGVGDDKLVYTYVPTMMEYYLREKPLLANVDTLRCWLDDERQEVLDRIHDLVLKPV
EGSGGYGIVFGPDASEKELAAASKKIRDDPRSWIAQPVMELSTVPTQVGSTLAPRYVDLRPFAVNDGNDVWVLPGGLTRV
ALVEGSRVVNSSQGGGSKDTWVLAPHASYGARELGAAEIVCSLPQSSPDPVPDGSPRPKQQPQQAQAEQAQQPQQQIMLP

Specific function: Unknown

COG id: COG2308

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To Synechocystis PCC 6803 sll0335 and to M.tuberculosis Rv2567

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y605_MYCLE (Q49755)

Other databases:

- EMBL:   U00016
- EMBL:   Z99125
- EMBL:   AL583919
- PIR:   T10046
- RefSeq:   NP_301510.1
- ProteinModelPortal:   Q49755
- EnsemblBacteria:   EBMYCT00000029333
- GeneID:   909390
- GenomeReviews:   AL450380_GR
- KEGG:   mle:ML0605
- NMPDR:   fig|272631.1.peg.382
- Leproma:   ML0605
- GeneTree:   EBGT00050000015557
- HOGENOM:   HBG668376
- OMA:   DTWVLED
- ProtClustDB:   CLSK872060
- BioCyc:   MLEP272631:ML0605-MONOMER
- InterPro:   IPR007297
- InterPro:   IPR007302
- InterPro:   IPR016450
- PIRSF:   PIRSF005522

Pfam domain/function: PF04169 DUF404; PF04174 DUF407

EC number: NA

Molecular weight: Translated: 61838; Mature: 61706

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQVSLPSQLKETGPRLQSRCRSSARSERIFGGYNTSDIYSMAFDEMFDVQGNVRGPYKG
CCCCCCHHHHHHCCHHHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHCCCCCCCCCHH
IYAELAPSDASELKARAEALARAFIDQGITFSLSGQERPFPLDLVPRVISASEWSRLERG
HHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
ITQRVKALEMYLDDIYGDQEILRDGVIPRRLITSCEHFHRQAVGIIPPNGVRIHVAGIDL
HHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEE
IRDDSGNFRVLEDNLRSPSGVSYVMENRRTIARVFPNLFATHRVRAVDDYASHLLRALRN
EECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAATNEADPTVVVLTPGVANAAYFEHSLLARQMGVELVEGRDLFCRDNQVYMCTTEGERQ
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCEEECCCCEEEECCEEEEEECCCCCH
VDVIYRRIDDAFLDPLQFRADSVLGVAGLVNAARAGNVVISSAIGNGVGDDKLVYTYVPT
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEHHHH
MMEYYLREKPLLANVDTLRCWLDDERQEVLDRIHDLVLKPVEGSGGYGIVFGPDASEKEL
HHHHHHHCCCCEECCHHHEEECCCHHHHHHHHHHHHHEECCCCCCCEEEEECCCCCHHHH
AAASKKIRDDPRSWIAQPVMELSTVPTQVGSTLAPRYVDLRPFAVNDGNDVWVLPGGLTR
HHHHHHHHCCHHHHHHHHHHHHHHCCHHHCCCCCCCEEECEEEEECCCCEEEEECCCCEE
VALVEGSRVVNSSQGGGSKDTWVLAPHASYGARELGAAEIVCSLPQSSPDPVPDGSPRPK
EEEEECCEEEECCCCCCCCCCEEEECCCCCCCHHCCHHHHEEECCCCCCCCCCCCCCCCC
QQPQQAQAEQAQQPQQQIMLP
CCHHHHHHHHHHCCHHHCCCC
>Mature Secondary Structure 
SQVSLPSQLKETGPRLQSRCRSSARSERIFGGYNTSDIYSMAFDEMFDVQGNVRGPYKG
CCCCCHHHHHHCCHHHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHCCCCCCCCCHH
IYAELAPSDASELKARAEALARAFIDQGITFSLSGQERPFPLDLVPRVISASEWSRLERG
HHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
ITQRVKALEMYLDDIYGDQEILRDGVIPRRLITSCEHFHRQAVGIIPPNGVRIHVAGIDL
HHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEE
IRDDSGNFRVLEDNLRSPSGVSYVMENRRTIARVFPNLFATHRVRAVDDYASHLLRALRN
EECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAATNEADPTVVVLTPGVANAAYFEHSLLARQMGVELVEGRDLFCRDNQVYMCTTEGERQ
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCEEECCCCEEEECCEEEEEECCCCCH
VDVIYRRIDDAFLDPLQFRADSVLGVAGLVNAARAGNVVISSAIGNGVGDDKLVYTYVPT
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEHHHH
MMEYYLREKPLLANVDTLRCWLDDERQEVLDRIHDLVLKPVEGSGGYGIVFGPDASEKEL
HHHHHHHCCCCEECCHHHEEECCCHHHHHHHHHHHHHEECCCCCCCEEEEECCCCCHHHH
AAASKKIRDDPRSWIAQPVMELSTVPTQVGSTLAPRYVDLRPFAVNDGNDVWVLPGGLTR
HHHHHHHHCCHHHHHHHHHHHHHHCCHHHCCCCCCCEEECEEEEECCCCEEEEECCCCEE
VALVEGSRVVNSSQGGGSKDTWVLAPHASYGARELGAAEIVCSLPQSSPDPVPDGSPRPK
EEEEECCEEEECCCCCCCCCCEEEECCCCCCCHHCCHHHHEEECCCCCCCCCCCCCCCCC
QQPQQAQAEQAQQPQQQIMLP
CCHHHHHHHHHHCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002