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The map label for this gene is aroB [H]

Identifier: 221229528

GI number: 221229528

Start: 336321

End: 337274

Strand: Direct

Name: aroB [H]

Synonym: MLBr_00258

Alternate gene names: 221229528

Gene position: 336321-337274 (Clockwise)

Preceding gene: 221229527

Following gene: 221229529

Centisome position: 10.29

GC content: 61.53

Gene sequence:

>954_bases
GTGAGTCGGGTCGCCGCGATTGACTGTGGTACCAACTCGATTCGGTTGCTGATTGCCGATGTGGCGGGCAGGAAGTTGCG
CGATGTGCATCGTGAGATGAGGATCGTGCGGCTGGGACAAGGAGTCGACGCAACGGGCGAGTTTGCGCTGGACGCGATTG
CCCGGACCCGGGCCGCGCTGGTCGATTATACTGCGCTGCTAAGTGCTCACCGCGTCGAACGGGTGCGCATGGTTGCCACG
TCGGCCGCGCGCGATGTCGTCAATCGTGATGTGCTCTTTGCAATGACAGCCGACGTGCTTGGCACCGTGATCCCTGGATC
TGTAGCGGAGGTGATCACCGGGGCCGAGGAAGCTGACCTGTCTTTTGATGGTGCTGTCGGCGAATTAGATAGCGCTGGTG
CGCCTTTCGTCGTTATCGACTTAGGTGGTGGATCTACCGAGATCGTTCTTGGTGGTGGTTCGGCGGAGTGCGGGGTCGTG
GCGAGCTATTCGGCCGACATCGGCTGCGTGCGGCTTACAGAACGTTGTTTGCACTCCGATCCGCCGACACCCGAGGAAGT
CGCTGCGGCCCGCAAGGTGGTACGTGAACGGCTCGAAGTGGCATTGCAGATGGTATCGGTTGAGCAAGCACGGACCTGGG
TTGGGCTGGCTGGGACGATGACCACACTGTCTGCCCTGGCACAGAATATGATGACGTACGACGCTGCGGCCATTCATCTT
TCGCGAGTGCGCGGCAGTGATCTCATGGAAGTCTGTGACAGGCTGATCGGCATGACGCGCGTACAGCGCGTCGCGCTGCC
GTCGATGCATGCGAGCCGGGCCGACGTGATCGGCGGTGGTGCGGTCCTGGTCCAGGAGTTGGTGCGCGAGCTGCGTACCT
GGGCGGGAATCGACGAGCTGATCGTCAGCGAACGTGACATTCTGGATGGCATCGTGCTCTCGATCGCGGGGTAA

Upstream 100 bases:

>100_bases
CCGGGTTGAACTCGCTCGGTGACGAGGTGCTCGCGCTGTTGGCCGCCGATCCGAAGACGGCTGCGACCCTAGTAGCAGGG
CAATGGAAGGAATGTGACCG

Downstream 100 bases:

>100_bases
GCTCCGGTCGATGTCACGGCTGGTACCGCAGAATTGTTGACCGAGTGGTGGGTTGCTTAAGGTTGACCAACGGTTTGTGG
TTCGCGCGGACATAGAGGAG

Product: hypothetical protein

Products: NA

Alternate protein names: 3-dehydroquinate synthase; Unknown phosphatase [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MSRVAAIDCGTNSIRLLIADVAGRKLRDVHREMRIVRLGQGVDATGEFALDAIARTRAALVDYTALLSAHRVERVRMVAT
SAARDVVNRDVLFAMTADVLGTVIPGSVAEVITGAEEADLSFDGAVGELDSAGAPFVVIDLGGGSTEIVLGGGSAECGVV
ASYSADIGCVRLTERCLHSDPPTPEEVAAARKVVRERLEVALQMVSVEQARTWVGLAGTMTTLSALAQNMMTYDAAAIHL
SRVRGSDLMEVCDRLIGMTRVQRVALPSMHASRADVIGGGAVLVQELVRELRTWAGIDELIVSERDILDGIVLSIAG

Sequences:

>Translated_317_residues
MSRVAAIDCGTNSIRLLIADVAGRKLRDVHREMRIVRLGQGVDATGEFALDAIARTRAALVDYTALLSAHRVERVRMVAT
SAARDVVNRDVLFAMTADVLGTVIPGSVAEVITGAEEADLSFDGAVGELDSAGAPFVVIDLGGGSTEIVLGGGSAECGVV
ASYSADIGCVRLTERCLHSDPPTPEEVAAARKVVRERLEVALQMVSVEQARTWVGLAGTMTTLSALAQNMMTYDAAAIHL
SRVRGSDLMEVCDRLIGMTRVQRVALPSMHASRADVIGGGAVLVQELVRELRTWAGIDELIVSERDILDGIVLSIAG
>Mature_316_residues
SRVAAIDCGTNSIRLLIADVAGRKLRDVHREMRIVRLGQGVDATGEFALDAIARTRAALVDYTALLSAHRVERVRMVATS
AARDVVNRDVLFAMTADVLGTVIPGSVAEVITGAEEADLSFDGAVGELDSAGAPFVVIDLGGGSTEIVLGGGSAECGVVA
SYSADIGCVRLTERCLHSDPPTPEEVAAARKVVRERLEVALQMVSVEQARTWVGLAGTMTTLSALAQNMMTYDAAAIHLS
RVRGSDLMEVCDRLIGMTRVQRVALPSMHASRADVIGGGAVLVQELVRELRTWAGIDELIVSERDILDGIVLSIAG

Specific function: Conversion Of Pppgpp To Ppgpp. Guanosine Pentaphosphate (Pppgpp) Is A Cytoplasmic Signaling Molecule Which Together With Ppgpp Controls The "Stringent Response", An Adaptive Process That Allows Bacteria To Respond To Amino Acid Starvation, Resulting In T

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI48994966, Length=293, Percent_Identity=28.3276450511945, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002658
- InterPro:   IPR016037
- InterPro:   IPR003695 [H]

Pfam domain/function: PF01761 DHQ_synthase; PF02541 Ppx-GppA [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 33490; Mature: 33359

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVAAIDCGTNSIRLLIADVAGRKLRDVHREMRIVRLGQGVDATGEFALDAIARTRAAL
CCCEEEEECCCCCEEEEEEHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
VDYTALLSAHRVERVRMVATSAARDVVNRDVLFAMTADVLGTVIPGSVAEVITGAEEADL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCC
SFDGAVGELDSAGAPFVVIDLGGGSTEIVLGGGSAECGVVASYSADIGCVRLTERCLHSD
CCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCEEEECCCCCHHHHHHHHHHCCC
PPTPEEVAAARKVVRERLEVALQMVSVEQARTWVGLAGTMTTLSALAQNMMTYDAAAIHL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRVRGSDLMEVCDRLIGMTRVQRVALPSMHASRADVIGGGAVLVQELVRELRTWAGIDEL
HHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHHHCCHHHH
IVSERDILDGIVLSIAG
HHHHHHHHHHHHHEECC
>Mature Secondary Structure 
SRVAAIDCGTNSIRLLIADVAGRKLRDVHREMRIVRLGQGVDATGEFALDAIARTRAAL
CCEEEEECCCCCEEEEEEHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
VDYTALLSAHRVERVRMVATSAARDVVNRDVLFAMTADVLGTVIPGSVAEVITGAEEADL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCC
SFDGAVGELDSAGAPFVVIDLGGGSTEIVLGGGSAECGVVASYSADIGCVRLTERCLHSD
CCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCEEEECCCCCHHHHHHHHHHCCC
PPTPEEVAAARKVVRERLEVALQMVSVEQARTWVGLAGTMTTLSALAQNMMTYDAAAIHL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRVRGSDLMEVCDRLIGMTRVQRVALPSMHASRADVIGGGAVLVQELVRELRTWAGIDEL
HHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHHHCCHHHH
IVSERDILDGIVLSIAG
HHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]