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The map label for this gene is pabB [H]

Identifier: 221229511

GI number: 221229511

Start: 309670

End: 310926

Strand: Reverse

Name: pabB [H]

Synonym: MLBr_00236

Alternate gene names: 221229511

Gene position: 310926-309670 (Counterclockwise)

Preceding gene: 221229512

Following gene: 221229496

Centisome position: 9.51

GC content: 63.56

Gene sequence:

>1257_bases
GTGCGAATCGAGCGACTCGGCAATCTTGGCGACGCACCCCGGGTGCTACGCTCTCTCGGCGACGCCACAACCGGGCTCGA
TTTGCCGCCGCCTGCCGCGCTGACCGGCGAGTGGTTCGATGCGCTGGCAATAATCGCGCCTAGTCTGTCAGTACAACCGG
TGGATGTTAACGACGCGTTTGCGGTCCAGTTAGACGCACGAACACCCGATTCGGCAGTAGCAGTAGGCGGAGGCTGGGTC
GGCTACCTGTCCTACCCAGACCCCGCAGCCGACAAGCAGCCGAACCGGATACCCGAAGCCGCCGGAGGTTGGACCGACTG
TGTGCTGCGCCGCGACCGTGGCGCGCAATGGTGGTACGAGAGCCTGTCCGGGGCACCGATGCCCGGCTGGCTGGCAGCCG
CACTAGCAACAACGCCGGCACCTGCGCGAAATTGCCAGGTAGACTGGGAGAGGACCGACTGGGGGGCCCATCGTGACGGG
GTACTTGCCTGCCTGGAGGCGATTCGTGCCGGCGAGATCTACCAAGCGTGTGTGTGCACACAGTTCACCGGAACAGTCAC
CGGGGCCCCGCTGGACTTCTTCATCGCTGTGGTGGCACGTACCGCACCGGCGCGTGCTGCTTATATCGCTGGACCGTGGG
GTGCGGTGGCATCGCTATCCCCGGAGCTATTCCTTCGACGCCGTGGTGCCGGCGTGACGTCCAGCCCGATCAAAGGCACC
CTGCCGTTGGCAGCCTGGCCGTCGGCATTACAAGCTTCGGCCAAAGAGGTGGCCGAGAACATCATGATCGTGGATCTGGT
GCGTAATGACCTCGGCCGGGTAGCCATTACCGGCACGGTCACCGTGCCCGAGCTGTTGGTTGTACGGCACGCTCCGGGCG
TGTGGCACCTAGTGTCCACGGTGACGGCCCAGGTGCCTGTCGAGCTGCCAATGGCGGCACTATTAGACGCCACCTTCCCG
CCAGCCTCGATCACTGGGACCCCCAAGCTAAGGGCCCGCAAATTGATTTCGCAATGGGAACACAGACGTCGCGGGATATA
TTGCGGCACAGTTGGTTTGGCATCACCAATCGCCGGATGTGAGCTGAACGTCGCGATCCGAACCGTCGAATTCGACACCG
CCGGTAACGCCGTGCTGGGAGTAGGCGGCGGGATAACCGCCGACTCCGATCCCGATGCCGAACTGCAAGAGTGCCTGCAT
AAAGCGGCACCTATTCTTAGGCTAGCATCCGTCGCTACCGTGGCGTCGGTCGGTTAG

Upstream 100 bases:

>100_bases
CGTAGTAAAACCGTGGTTCGATGGCGGAGCCAGAGGCGAGCCAATCCAACCTAGATGACGCCTGGAGTGAGAAAATCGGC
TGTTCTGTCAAGCTAGTGCG

Downstream 100 bases:

>100_bases
CCCGGCAAAATTTCTGATAACACTCACAACGCAGGCCCCGCGTACCTGAAGTTCCACTCCAGCGCATAGACCCATGTATC
GTGAGTCGACGGCGATCCGA

Product: aminodeoxychorismate synthase component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MRIERLGNLGDAPRVLRSLGDATTGLDLPPPAALTGEWFDALAIIAPSLSVQPVDVNDAFAVQLDARTPDSAVAVGGGWV
GYLSYPDPAADKQPNRIPEAAGGWTDCVLRRDRGAQWWYESLSGAPMPGWLAAALATTPAPARNCQVDWERTDWGAHRDG
VLACLEAIRAGEIYQACVCTQFTGTVTGAPLDFFIAVVARTAPARAAYIAGPWGAVASLSPELFLRRRGAGVTSSPIKGT
LPLAAWPSALQASAKEVAENIMIVDLVRNDLGRVAITGTVTVPELLVVRHAPGVWHLVSTVTAQVPVELPMAALLDATFP
PASITGTPKLRARKLISQWEHRRRGIYCGTVGLASPIAGCELNVAIRTVEFDTAGNAVLGVGGGITADSDPDAELQECLH
KAAPILRLASVATVASVG

Sequences:

>Translated_418_residues
MRIERLGNLGDAPRVLRSLGDATTGLDLPPPAALTGEWFDALAIIAPSLSVQPVDVNDAFAVQLDARTPDSAVAVGGGWV
GYLSYPDPAADKQPNRIPEAAGGWTDCVLRRDRGAQWWYESLSGAPMPGWLAAALATTPAPARNCQVDWERTDWGAHRDG
VLACLEAIRAGEIYQACVCTQFTGTVTGAPLDFFIAVVARTAPARAAYIAGPWGAVASLSPELFLRRRGAGVTSSPIKGT
LPLAAWPSALQASAKEVAENIMIVDLVRNDLGRVAITGTVTVPELLVVRHAPGVWHLVSTVTAQVPVELPMAALLDATFP
PASITGTPKLRARKLISQWEHRRRGIYCGTVGLASPIAGCELNVAIRTVEFDTAGNAVLGVGGGITADSDPDAELQECLH
KAAPILRLASVATVASVG
>Mature_418_residues
MRIERLGNLGDAPRVLRSLGDATTGLDLPPPAALTGEWFDALAIIAPSLSVQPVDVNDAFAVQLDARTPDSAVAVGGGWV
GYLSYPDPAADKQPNRIPEAAGGWTDCVLRRDRGAQWWYESLSGAPMPGWLAAALATTPAPARNCQVDWERTDWGAHRDG
VLACLEAIRAGEIYQACVCTQFTGTVTGAPLDFFIAVVARTAPARAAYIAGPWGAVASLSPELFLRRRGAGVTSSPIKGT
LPLAAWPSALQASAKEVAENIMIVDLVRNDLGRVAITGTVTVPELLVVRHAPGVWHLVSTVTAQVPVELPMAALLDATFP
PASITGTPKLRARKLISQWEHRRRGIYCGTVGLASPIAGCELNVAIRTVEFDTAGNAVLGVGGGITADSDPDAELQECLH
KAAPILRLASVATVASVG

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=289, Percent_Identity=38.0622837370242, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1787518, Length=298, Percent_Identity=28.1879194630872, Blast_Score=101, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6320935, Length=366, Percent_Identity=27.0491803278689, Blast_Score=106, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6324361, Length=281, Percent_Identity=29.1814946619217, Blast_Score=87, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 43847; Mature: 43847

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIERLGNLGDAPRVLRSLGDATTGLDLPPPAALTGEWFDALAIIAPSLSVQPVDVNDAF
CCCHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCEE
AVQLDARTPDSAVAVGGGWVGYLSYPDPAADKQPNRIPEAAGGWTDCVLRRDRGAQWWYE
EEEEECCCCCCEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHEECCCCCHHHHH
SLSGAPMPGWLAAALATTPAPARNCQVDWERTDWGAHRDGVLACLEAIRAGEIYQACVCT
HCCCCCCCHHHHHHHHCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHH
QFTGTVTGAPLDFFIAVVARTAPARAAYIAGPWGAVASLSPELFLRRRGAGVTSSPIKGT
HCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHCCHHHHHHHCCCCCCCCCCCCC
LPLAAWPSALQASAKEVAENIMIVDLVRNDLGRVAITGTVTVPELLVVRHAPGVWHLVST
CCHHHCHHHHHHHHHHHHHCCEEEEEHHCCCCCEEEEECEEHHHHHEEECCCCHHHHHHH
VTAQVPVELPMAALLDATFPPASITGTPKLRARKLISQWEHRRRGIYCGTVGLASPIAGC
HHHHCCHHCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCHHCCCCCCC
ELNVAIRTVEFDTAGNAVLGVGGGITADSDPDAELQECLHKAAPILRLASVATVASVG
EEEEEEEEEEECCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRIERLGNLGDAPRVLRSLGDATTGLDLPPPAALTGEWFDALAIIAPSLSVQPVDVNDAF
CCCHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCEE
AVQLDARTPDSAVAVGGGWVGYLSYPDPAADKQPNRIPEAAGGWTDCVLRRDRGAQWWYE
EEEEECCCCCCEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHEECCCCCHHHHH
SLSGAPMPGWLAAALATTPAPARNCQVDWERTDWGAHRDGVLACLEAIRAGEIYQACVCT
HCCCCCCCHHHHHHHHCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHH
QFTGTVTGAPLDFFIAVVARTAPARAAYIAGPWGAVASLSPELFLRRRGAGVTSSPIKGT
HCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHCCHHHHHHHCCCCCCCCCCCCC
LPLAAWPSALQASAKEVAENIMIVDLVRNDLGRVAITGTVTVPELLVVRHAPGVWHLVST
CCHHHCHHHHHHHHHHHHHCCEEEEEHHCCCCCEEEEECEEHHHHHEEECCCCHHHHHHH
VTAQVPVELPMAALLDATFPPASITGTPKLRARKLISQWEHRRRGIYCGTVGLASPIAGC
HHHHCCHHCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCHHCCCCCCC
ELNVAIRTVEFDTAGNAVLGVGGGITADSDPDAELQECLHKAAPILRLASVATVASVG
EEEEEEEEEEECCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6330050; 9097040; 9278503; 7896119; 2251281; 7592344 [H]