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The map label for this gene is 221229484

Identifier: 221229484

GI number: 221229484

Start: 268872

End: 270464

Strand: Reverse

Name: 221229484

Synonym: MLBr_00201

Alternate gene names: NA

Gene position: 270464-268872 (Counterclockwise)

Preceding gene: 221229486

Following gene: 221229479

Centisome position: 8.28

GC content: 63.72

Gene sequence:

>1593_bases
GTGGCAACCCAGGCGGCAGGACTGCCCGGGCGGATCGGTGCGTTCGTCCGGTGGGGTATACGCACCCCGTGGCCACTGTT
CTCGCTTAGCATGCTGCAGTCTGACATCATCGGCGCCCTGTTCGTGCTCGGTTTCCTCCGCTACGGTTTGCCACCCCAGG
ACCGCGTTGAGCTGCAGGATCTGCCCATCCGCAACTTGGCAATCTCCACCCTCTCGGTGGTCGTGGCGTTCTCCACCGGG
TTCGCAGTGAACCTGAAACTACTGATGCCAGTTTTCCGATGGCAGCGCCGTGACAACCGGCTCGCCGAAGCTGATCCTGC
CGCGACCGAACTGGCCCGGAGCCGAGCACTGCGCATGCCCTTTTATCACACCATCATCAGCCTGGTGACCTGGGGCATCG
GTGGGGCAGTATTCATCATCGCCAGCTGGTCGGCAGCCAGGCATTCAGCACCTATCGTGGCGCTCGCTACCGCACTAGGC
GCCACCGCTACCGCAATCATCGGCTACCTGCAGTCTGAGCGGGTCCTGCGACCGGTGGCCGTGGCAGCCCTGCGCAGCGG
CGTGCCAGAGAACGTCAAAACACCCGGCGTAACTTTGCGGCTGATGTTGACCTGGGTGCCGTCCACTGGAGTACCGGTCC
TGGCGATCGTGCTGGCAGTGGTGGCCGACAAAATTGCCTTGCTGCATGCCGTGCCGGAACAGTTATTCAGCCCCATTCTG
CTGCTGGCACTGGCGGTGCTGGTCGTCGGACTGGTGAGCACCTGGTTGGTGGCCATGTCGATCGCCGATCCGCTGCGACA
ACTGCGCTGGGCACTATCCGAGGTTCAGCGCGGCAACTACAACGCGCACATGCAGATCTACGACGCCAGTGAGCTGGGCT
TATTGCAAGCCGGCTTCAACGACATGGTGCGTGAGCTGTCCGAGCGGCAGCGGCTTCGTGACCTGTTCGGTCGCTACGTC
GGCGAAGACGTGGCCCGCCGAGCCTTGGAGCACGGCACCGAGTTGGGTGGGCAGGAGCGCGACGTCGCGGTGCTGTTCGT
GGACCTGATAGGCTCCACCCAGCTGGCCGAGACAAAACCACCCACCAAAGTGGTTCATCTCCTCAACGAGTTCTTCCGTG
TGGTCGTGGACACCGTTGGGCGACACGGCGGGTTCGTCAACAAGTTCCAGGGCGATGCCGCGCTGGCAATCTTCGGAGCG
CCGATCGAGCACCCGGACAGTGCTGGTGCGGCGCTGTCGGCCGCCCGTGAGCTGCACGATGAACTCCTACCGGTGCTGGG
TAGTGCAGAGTTCGGCATCGGGGTGTCGGCCGGCAGGGCCATCGCCGGCCATATCGGCGCGCAAGCCCGCTTCGAGTACA
CCGTGATCGGCGACCCAGTCAACGAGGCAGCGAGGCTCACCGAACTGGCCAAACTCGAGGACGGCCATGTGCTCGCATCG
GCAATAGCAGTCAGCGGGGCGCTCGACGCCGAAGCCTTGTGCTGGAACGTCGGCGAAATCGTCGAACTACGCGGACGCAC
CGCACCCACTCAGCTTGCCCGACCGCTGAATCTTGCTGTCCCTGAACAGATCACTAGCGAGGTGACTGGCTGA

Upstream 100 bases:

>100_bases
AACATTTCCGTAACCTTATAACCGCCCGCACAGCCGTCCCATAACCGGCAAAGGCGCTGGAGGTTGCCAACAAATCGCCG
CAGACCGATACGGTGAGGTA

Downstream 100 bases:

>100_bases
TCCCGCGGGCCGGAGCCAGTCTAGCTGCCTTCTTCGCCGGGACCTTGCGAGCCTTCTTAGCAGGCCGCTTAACCGGACCT
CGGGCCCGTCGGTCAGCCAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 530; Mature: 529

Protein sequence:

>530_residues
MATQAAGLPGRIGAFVRWGIRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDRVELQDLPIRNLAISTLSVVVAFSTG
FAVNLKLLMPVFRWQRRDNRLAEADPAATELARSRALRMPFYHTIISLVTWGIGGAVFIIASWSAARHSAPIVALATALG
ATATAIIGYLQSERVLRPVAVAALRSGVPENVKTPGVTLRLMLTWVPSTGVPVLAIVLAVVADKIALLHAVPEQLFSPIL
LLALAVLVVGLVSTWLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSERQRLRDLFGRYV
GEDVARRALEHGTELGGQERDVAVLFVDLIGSTQLAETKPPTKVVHLLNEFFRVVVDTVGRHGGFVNKFQGDAALAIFGA
PIEHPDSAGAALSAARELHDELLPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLAS
AIAVSGALDAEALCWNVGEIVELRGRTAPTQLARPLNLAVPEQITSEVTG

Sequences:

>Translated_530_residues
MATQAAGLPGRIGAFVRWGIRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDRVELQDLPIRNLAISTLSVVVAFSTG
FAVNLKLLMPVFRWQRRDNRLAEADPAATELARSRALRMPFYHTIISLVTWGIGGAVFIIASWSAARHSAPIVALATALG
ATATAIIGYLQSERVLRPVAVAALRSGVPENVKTPGVTLRLMLTWVPSTGVPVLAIVLAVVADKIALLHAVPEQLFSPIL
LLALAVLVVGLVSTWLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSERQRLRDLFGRYV
GEDVARRALEHGTELGGQERDVAVLFVDLIGSTQLAETKPPTKVVHLLNEFFRVVVDTVGRHGGFVNKFQGDAALAIFGA
PIEHPDSAGAALSAARELHDELLPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLAS
AIAVSGALDAEALCWNVGEIVELRGRTAPTQLARPLNLAVPEQITSEVTG
>Mature_529_residues
ATQAAGLPGRIGAFVRWGIRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDRVELQDLPIRNLAISTLSVVVAFSTGF
AVNLKLLMPVFRWQRRDNRLAEADPAATELARSRALRMPFYHTIISLVTWGIGGAVFIIASWSAARHSAPIVALATALGA
TATAIIGYLQSERVLRPVAVAALRSGVPENVKTPGVTLRLMLTWVPSTGVPVLAIVLAVVADKIALLHAVPEQLFSPILL
LALAVLVVGLVSTWLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSERQRLRDLFGRYVG
EDVARRALEHGTELGGQERDVAVLFVDLIGSTQLAETKPPTKVVHLLNEFFRVVVDTVGRHGGFVNKFQGDAALAIFGAP
IEHPDSAGAALSAARELHDELLPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASA
IAVSGALDAEALCWNVGEIVELRGRTAPTQLARPLNLAVPEQITSEVTG

Specific function: Unknown

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00672 HAMP [H]

EC number: NA

Molecular weight: Translated: 56883; Mature: 56752

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS50885 HAMP ; PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATQAAGLPGRIGAFVRWGIRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDRVELQD
CCCCCCCCCHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHC
LPIRNLAISTLSVVVAFSTGFAVNLKLLMPVFRWQRRDNRLAEADPAATELARSRALRMP
CCCHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCH
FYHTIISLVTWGIGGAVFIIASWSAARHSAPIVALATALGATATAIIGYLQSERVLRPVA
HHHHHHHHHHHCCCCEEEEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAALRSGVPENVKTPGVTLRLMLTWVPSTGVPVLAIVLAVVADKIALLHAVPEQLFSPIL
HHHHHCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLALAVLVVGLVSTWLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECHHCCHHHHCHH
DMVRELSERQRLRDLFGRYVGEDVARRALEHGTELGGQERDVAVLFVDLIGSTQLAETKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEEEHHCCCCCCCCCC
PTKVVHLLNEFFRVVVDTVGRHGGFVNKFQGDAALAIFGAPIEHPDSAGAALSAARELHD
HHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHH
ELLPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLAS
HHHHHHCCCCCCCCCCCCCHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCHHHHH
AIAVSGALDAEALCWNVGEIVELRGRTAPTQLARPLNLAVPEQITSEVTG
HHHHHCCCCHHHHHHCHHHHHHHCCCCCHHHHCCCCCCCCCHHHHHHCCC
>Mature Secondary Structure 
ATQAAGLPGRIGAFVRWGIRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDRVELQD
CCCCCCCCHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHC
LPIRNLAISTLSVVVAFSTGFAVNLKLLMPVFRWQRRDNRLAEADPAATELARSRALRMP
CCCHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCH
FYHTIISLVTWGIGGAVFIIASWSAARHSAPIVALATALGATATAIIGYLQSERVLRPVA
HHHHHHHHHHHCCCCEEEEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAALRSGVPENVKTPGVTLRLMLTWVPSTGVPVLAIVLAVVADKIALLHAVPEQLFSPIL
HHHHHCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLALAVLVVGLVSTWLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECHHCCHHHHCHH
DMVRELSERQRLRDLFGRYVGEDVARRALEHGTELGGQERDVAVLFVDLIGSTQLAETKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEEEHHCCCCCCCCCC
PTKVVHLLNEFFRVVVDTVGRHGGFVNKFQGDAALAIFGAPIEHPDSAGAALSAARELHD
HHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHH
ELLPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLAS
HHHHHHCCCCCCCCCCCCCHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCHHHHH
AIAVSGALDAEALCWNVGEIVELRGRTAPTQLARPLNLAVPEQITSEVTG
HHHHHCCCCHHHHHHCHHHHHHHCCCCCHHHHCCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]