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The map label for this gene is 221229436

Identifier: 221229436

GI number: 221229436

Start: 170689

End: 171378

Strand: Direct

Name: 221229436

Synonym: MLBr_00127

Alternate gene names: NA

Gene position: 170689-171378 (Clockwise)

Preceding gene: 221229435

Following gene: 221229437

Centisome position: 5.22

GC content: 48.99

Gene sequence:

>690_bases
ATGGAACGAGTACGACAAATGTTCAGTTGTGTGTCCGGAATGATTTACCGGCCTACCGATTCTATAGCCGAAGAATATCA
CAAATGGTATTACGGCAACTTTGTGTGGAATACTACTACTTGGATGGGGATTAAATGCTTGAAGTCGGTCAGCGATATGT
GGAACTACCAGGAAATCCTGATCGAGTTGGAACCCTCCCTGGTCATAGAGTTCGGTAGCCGCTTCGGTGGCTCTGCGCTT
TTTTTTGCCAACGTCATGATGCACATCGGCCAACCGTTCAAGGTGCTCTCGGTGGATATTTCTCACAAGGATCTCGACCC
AGCAGCGCGCCAACCAGATATTTTGTTCATCGAATCACCATCTACCGCGCCGGCGATCGCCGAGCAAATTCGACGCCTTA
AAAATGAATACCCCGGTAAGATCTTCGCCATCTTGGACAGTGATCACTCGATGAAACAAGTACTGGCCGAGATGAAACTA
CTACAACCTTTACTCACCGCTGGTGACTATCTGGTCGTGGAAGATTCTAATCTCAATGGCCATCCCGTTCTTCCGCGGTT
TGGCGCCGGCCCGTATGAAGCCATTGAGGCATACGAGCGTGAATTTCCGGGTGATTACGAGCACGATGTCGCACGGGAGA
AAAAATTCGGATTTACATTCGCGACCAACGGATTCTTGATCCGCAAATAA

Upstream 100 bases:

>100_bases
ATCGGTTATGTTGTCAAATTGAAGCAACATCAGTATTTATATTGGAATTCTGCTACGGACAATGTGTTCGCATTGCTAGG
GCTATACGAGGAGATGAGGA

Downstream 100 bases:

>100_bases
GAGCATATAGTGTGAGGCAACTCGACGACCTCATCTCGAGCAGCCTAGACGTCAGTAATCACCATTGGATTATTACCGCC
CGGGCGTTCGACCAACGAAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MERVRQMFSCVSGMIYRPTDSIAEEYHKWYYGNFVWNTTTWMGIKCLKSVSDMWNYQEILIELEPSLVIEFGSRFGGSAL
FFANVMMHIGQPFKVLSVDISHKDLDPAARQPDILFIESPSTAPAIAEQIRRLKNEYPGKIFAILDSDHSMKQVLAEMKL
LQPLLTAGDYLVVEDSNLNGHPVLPRFGAGPYEAIEAYEREFPGDYEHDVAREKKFGFTFATNGFLIRK

Sequences:

>Translated_229_residues
MERVRQMFSCVSGMIYRPTDSIAEEYHKWYYGNFVWNTTTWMGIKCLKSVSDMWNYQEILIELEPSLVIEFGSRFGGSAL
FFANVMMHIGQPFKVLSVDISHKDLDPAARQPDILFIESPSTAPAIAEQIRRLKNEYPGKIFAILDSDHSMKQVLAEMKL
LQPLLTAGDYLVVEDSNLNGHPVLPRFGAGPYEAIEAYEREFPGDYEHDVAREKKFGFTFATNGFLIRK
>Mature_229_residues
MERVRQMFSCVSGMIYRPTDSIAEEYHKWYYGNFVWNTTTWMGIKCLKSVSDMWNYQEILIELEPSLVIEFGSRFGGSAL
FFANVMMHIGQPFKVLSVDISHKDLDPAARQPDILFIESPSTAPAIAEQIRRLKNEYPGKIFAILDSDHSMKQVLAEMKL
LQPLLTAGDYLVVEDSNLNGHPVLPRFGAGPYEAIEAYEREFPGDYEHDVAREKKFGFTFATNGFLIRK

Specific function: Catalyzes the O-methylation of the hydroxyl group located on C-2 of the first rhamnosyl residue linked to the phenolic group of glycosylated phenolphthiocerol dimycocerosates (PGL) and p-hydroxybenzoic acid derivatives (p-HBAD)

COG id: COG3510

COG function: function code V; Cephalosporin hydroxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rhamnosyl O-methyltransferase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNMT_MYCLE (Q9CD89)

Other databases:

- EMBL:   AL583917
- PIR:   G86924
- RefSeq:   NP_301221.1
- ProteinModelPortal:   Q9CD89
- SMR:   Q9CD89
- EnsemblBacteria:   EBMYCT00000029119
- GeneID:   908423
- GenomeReviews:   AL450380_GR
- KEGG:   mle:ML0127
- NMPDR:   fig|272631.1.peg.93
- Leproma:   ML0127
- GeneTree:   EBGT00050000018653
- HOGENOM:   HBG336035
- OMA:   DEARECK
- ProtClustDB:   CLSK792190
- BioCyc:   MLEP272631:ML0127-MONOMER
- InterPro:   IPR007072

Pfam domain/function: PF04989 CmcI

EC number: NA

Molecular weight: Translated: 26203; Mature: 26203

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERVRQMFSCVSGMIYRPTDSIAEEYHKWYYGNFVWNTTTWMGIKCLKSVSDMWNYQEIL
CHHHHHHHHHHCCEEECCCHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHCHHHHH
IELEPSLVIEFGSRFGGSALFFANVMMHIGQPFKVLSVDISHKDLDPAARQPDILFIESP
EECCCHHEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEEECC
STAPAIAEQIRRLKNEYPGKIFAILDSDHSMKQVLAEMKLLQPLLTAGDYLVVEDSNLNG
CCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
HPVLPRFGAGPYEAIEAYEREFPGDYEHDVAREKKFGFTFATNGFLIRK
CCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCEEEECCCEEEEC
>Mature Secondary Structure
MERVRQMFSCVSGMIYRPTDSIAEEYHKWYYGNFVWNTTTWMGIKCLKSVSDMWNYQEIL
CHHHHHHHHHHCCEEECCCHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHCHHHHH
IELEPSLVIEFGSRFGGSALFFANVMMHIGQPFKVLSVDISHKDLDPAARQPDILFIESP
EECCCHHEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEEECC
STAPAIAEQIRRLKNEYPGKIFAILDSDHSMKQVLAEMKLLQPLLTAGDYLVVEDSNLNG
CCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
HPVLPRFGAGPYEAIEAYEREFPGDYEHDVAREKKFGFTFATNGFLIRK
CCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCEEEECCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002