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The map label for this gene is eccE1 [H]

Identifier: 221229373

GI number: 221229373

Start: 51989

End: 53392

Strand: Direct

Name: eccE1 [H]

Synonym: MLBr_00042

Alternate gene names: 221229373

Gene position: 51989-53392 (Clockwise)

Preceding gene: 221229372

Following gene: 221229374

Centisome position: 1.59

GC content: 59.33

Gene sequence:

>1404_bases
ATGAGGAATCCAGTATGGCTACGTTTCAGCATGGGACGTGCACTGCTCGTCACAGCGTTGGTTCCGCCATGCATCATATT
GTTTTTTCACACCCAATACTGGTGGGCCGGCATTGCGTTGGTGGTGTTGGTCGTGATCCTGACCCTGGTCGAATTTTCCG
GGCGGTGGCTAAGCGGCTGGTTGATGGCACTCTATTCATTCTTCCGGCGTAGTAGTAAGCCGTTGGACACTCCGTCGGAA
CCGGTGATCGGTGCCACCGTGAAACCTGCAGATCAAGTTATTATGCGCTGGCAAGATGGGTTCCTGGTCTCGGTCGTCGA
ACTGATTCCCAGACCATTTACACCGACAGTCATTGTCGATGGAGAAGCGCAGACCGACGACTTGCTGGAGACTCAGCTGT
TGGAGCACCTGTTGTCGGTGCACTGTCCGGACTTGGAAGCGGTTGTTGTGTCCGCAGGTTATCGTGTCGGCCACGTTGCG
TCACTAGACGTCGTCAACCTGTACCAGCAGGTGATCGGTGCCGACCCGGCGCCCGCGCATCGTCGAACCTGGATCATGCT
GCGTGCTGACCCTGTGCGCACCCGCAAGTCCGCACAGCGGCGTGACGCCGGCGTAGCGGGATTGGCCCGGTATCTGATCG
CGTCTACGACGCGTATCGCAGATCAGTTGGCTAGCCATGGTGTGGACGCGGTCTGTGGACACAGCTTCGAGAGCGTCGAC
CACGCTACCGATGTCGGCTTCATGCAGGAGAAGTGGTCGATGATGCGGGGGCAAAACGCGTACAGCGTAGCTTACACTGC
GCCCGCTGGTCCGGATGCGTGGTGGTCGGCGCGGGCCGATCACACGATCACCCGGGTCCGGGTGGCTCCTGGGAAGACGC
CGCAGGCCACGGTGGTGCTGACGACGCTCGGGAAACCCAAAACGCCATGTGGGTTTTACCGTCTGCACGGTGCCCAGCAG
CCGGCATTGCTGGGCCGAAGCTTCGTTGCCTACCAGCATTGCCAGATGCCGATAGGATCAGCGGGTGTACTCGTTGGCGA
GACAGTGAACCGGTGTTCGGTTTACATGCCGTTCGACGATGTCGACGTGAGCGTCAGCTTGGGTGACGTCCAGACGTTCA
CGCAGTTCGTGGTACGTGCGGCGGCTGCAGGTGGCATCGTCACACTCGGACAGCAATTCGAGAAATTCGCTAGGATGATC
GGTGGGCAGATCGGGTCGGTGGCGAAGGTGGCGTGGCCTAATGCGACGACCTATCTCGACCCCTACCCCGGCAGCGAGCG
GGTGATACTTAAGCATGATATCATTGGCACTCCGCGGCATCGCAAGTTGCCGATCCGCAGGATTTCCCCCCCTGAGGAAG
GCCATTACCAGATGGTGCTACCAAAGAGTAGCTACGAACTGTGA

Upstream 100 bases:

>100_bases
GCCCTGATCGCAACACGATCATGATTGTGGCTCAAGGGATCTTGGGCTTGTCGATAGCGCTGGGACTGGGTGTACTGGTT
AGGCGGGCGCTACAACGCCA

Downstream 100 bases:

>100_bases
TAGCGTCCGTTCTTGCAGTGTAGCACGATTTGGGTGTCGATTACGCTACCGATAGGTTATTGCCTGCATGAGATTATGAC
AGGGTCCCAAAAGAAATTCT

Product: hypothetical protein

Products: NA

Alternate protein names: ESX conserved component E1; Type VII secretion system protein EccE1; T7SS protein EccE1 [H]

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MRNPVWLRFSMGRALLVTALVPPCIILFFHTQYWWAGIALVVLVVILTLVEFSGRWLSGWLMALYSFFRRSSKPLDTPSE
PVIGATVKPADQVIMRWQDGFLVSVVELIPRPFTPTVIVDGEAQTDDLLETQLLEHLLSVHCPDLEAVVVSAGYRVGHVA
SLDVVNLYQQVIGADPAPAHRRTWIMLRADPVRTRKSAQRRDAGVAGLARYLIASTTRIADQLASHGVDAVCGHSFESVD
HATDVGFMQEKWSMMRGQNAYSVAYTAPAGPDAWWSARADHTITRVRVAPGKTPQATVVLTTLGKPKTPCGFYRLHGAQQ
PALLGRSFVAYQHCQMPIGSAGVLVGETVNRCSVYMPFDDVDVSVSLGDVQTFTQFVVRAAAAGGIVTLGQQFEKFARMI
GGQIGSVAKVAWPNATTYLDPYPGSERVILKHDIIGTPRHRKLPIRRISPPEEGHYQMVLPKSSYEL

Sequences:

>Translated_467_residues
MRNPVWLRFSMGRALLVTALVPPCIILFFHTQYWWAGIALVVLVVILTLVEFSGRWLSGWLMALYSFFRRSSKPLDTPSE
PVIGATVKPADQVIMRWQDGFLVSVVELIPRPFTPTVIVDGEAQTDDLLETQLLEHLLSVHCPDLEAVVVSAGYRVGHVA
SLDVVNLYQQVIGADPAPAHRRTWIMLRADPVRTRKSAQRRDAGVAGLARYLIASTTRIADQLASHGVDAVCGHSFESVD
HATDVGFMQEKWSMMRGQNAYSVAYTAPAGPDAWWSARADHTITRVRVAPGKTPQATVVLTTLGKPKTPCGFYRLHGAQQ
PALLGRSFVAYQHCQMPIGSAGVLVGETVNRCSVYMPFDDVDVSVSLGDVQTFTQFVVRAAAAGGIVTLGQQFEKFARMI
GGQIGSVAKVAWPNATTYLDPYPGSERVILKHDIIGTPRHRKLPIRRISPPEEGHYQMVLPKSSYEL
>Mature_467_residues
MRNPVWLRFSMGRALLVTALVPPCIILFFHTQYWWAGIALVVLVVILTLVEFSGRWLSGWLMALYSFFRRSSKPLDTPSE
PVIGATVKPADQVIMRWQDGFLVSVVELIPRPFTPTVIVDGEAQTDDLLETQLLEHLLSVHCPDLEAVVVSAGYRVGHVA
SLDVVNLYQQVIGADPAPAHRRTWIMLRADPVRTRKSAQRRDAGVAGLARYLIASTTRIADQLASHGVDAVCGHSFESVD
HATDVGFMQEKWSMMRGQNAYSVAYTAPAGPDAWWSARADHTITRVRVAPGKTPQATVVLTTLGKPKTPCGFYRLHGAQQ
PALLGRSFVAYQHCQMPIGSAGVLVGETVNRCSVYMPFDDVDVSVSLGDVQTFTQFVVRAAAAGGIVTLGQQFEKFARMI
GGQIGSVAKVAWPNATTYLDPYPGSERVILKHDIIGTPRHRKLPIRRISPPEEGHYQMVLPKSSYEL

Specific function: Could be part of a complex that is involved in secretion of ESX-1 substrates, such as EsxA (ESAT-6) and EsxB (CFP-10) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EccE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021368 [H]

Pfam domain/function: PF11203 DUF2984 [H]

EC number: NA

Molecular weight: Translated: 51423; Mature: 51423

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNPVWLRFSMGRALLVTALVPPCIILFFHTQYWWAGIALVVLVVILTLVEFSGRWLSGW
CCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LMALYSFFRRSSKPLDTPSEPVIGATVKPADQVIMRWQDGFLVSVVELIPRPFTPTVIVD
HHHHHHHHHCCCCCCCCCCCCEECCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEC
GEAQTDDLLETQLLEHLLSVHCPDLEAVVVSAGYRVGHVASLDVVNLYQQVIGADPAPAH
CCCCCHHHHHHHHHHHHHHCCCCCHHEEEEECCCCCCCEEHHHHHHHHHHHHCCCCCCCC
RRTWIMLRADPVRTRKSAQRRDAGVAGLARYLIASTTRIADQLASHGVDAVCGHSFESVD
CEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHH
HATDVGFMQEKWSMMRGQNAYSVAYTAPAGPDAWWSARADHTITRVRVAPGKTPQATVVL
HHHCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEE
TTLGKPKTPCGFYRLHGAQQPALLGRSFVAYQHCQMPIGSAGVLVGETVNRCSVYMPFDD
EECCCCCCCCCHHEECCCCCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCEEEECCCC
VDVSVSLGDVQTFTQFVVRAAAAGGIVTLGQQFEKFARMIGGQIGSVAKVAWPNATTYLD
CEEEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEC
PYPGSERVILKHDIIGTPRHRKLPIRRISPPEEGHYQMVLPKSSYEL
CCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure
MRNPVWLRFSMGRALLVTALVPPCIILFFHTQYWWAGIALVVLVVILTLVEFSGRWLSGW
CCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LMALYSFFRRSSKPLDTPSEPVIGATVKPADQVIMRWQDGFLVSVVELIPRPFTPTVIVD
HHHHHHHHHCCCCCCCCCCCCEECCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEC
GEAQTDDLLETQLLEHLLSVHCPDLEAVVVSAGYRVGHVASLDVVNLYQQVIGADPAPAH
CCCCCHHHHHHHHHHHHHHCCCCCHHEEEEECCCCCCCEEHHHHHHHHHHHHCCCCCCCC
RRTWIMLRADPVRTRKSAQRRDAGVAGLARYLIASTTRIADQLASHGVDAVCGHSFESVD
CEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHH
HATDVGFMQEKWSMMRGQNAYSVAYTAPAGPDAWWSARADHTITRVRVAPGKTPQATVVL
HHHCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEE
TTLGKPKTPCGFYRLHGAQQPALLGRSFVAYQHCQMPIGSAGVLVGETVNRCSVYMPFDD
EECCCCCCCCCHHEECCCCCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCEEEECCCC
VDVSVSLGDVQTFTQFVVRAAAAGGIVTLGQQFEKFARMIGGQIGSVAKVAWPNATTYLD
CEEEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEC
PYPGSERVILKHDIIGTPRHRKLPIRRISPPEEGHYQMVLPKSSYEL
CCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]