Click here to switch to the map view.

The map label for this gene is pabA [H]

Identifier: 221229356

GI number: 221229356

Start: 18321

End: 19019

Strand: Direct

Name: pabA [H]

Synonym: MLBr_00015

Alternate gene names: 221229356

Gene position: 18321-19019 (Clockwise)

Preceding gene: 221229353

Following gene: 221229365

Centisome position: 0.56

GC content: 57.8

Gene sequence:

>699_bases
ATGCGGATCTTGGTCATTGACAACTATGACAGCTTTGTGTTCAACCTGGTACAGTATCTCGGGCAGCTCGGAGTAGACGC
TGAGGTGTGGCGCAACGACGATACCCGATTATCCGACGAATCCACTATCGCTGCACAGTTCGACGGTATCCTGCTTAGTC
CAGGTCCTGGCACTCCGGAACGTGCGGGGGCGTCGATCAATCTGGTCCGGGTGTGCGCCGCGGCGCACACCCCATTGCTA
GGAGTCTGCCTGGGCCACCAGGCTATTGGCGTATCGTTCGGCGCCACCGTGGACCGCGCTCCCGAGTTGTTACACGGCAA
GACCAGCAGTGTATTTCATACGAATAACGGTGTGCTACAAGGACTTCCAAATCCATTCACGGCTACCCGATATCATTCAT
TAACTATCTTGCCGGAGTCACTTCCGCCGGTATTGGAGGTCGTCGCGCGCACACGTAGCGGTGTGATCATGGCGGTGCGT
CACACCGAGTTGCCGATCCACGGTGTCCAGTTCCACCCGGAGTCGATCTTGACCGAGGGTGGGCATAGACTGTTGGCTAA
TTGGCTGACCTATTGCGGATGGTTGTGTGACGACGCACTGATCCGCCGACTTGAGAATGAGGTCGATGCTGCGGTCCATC
CGCGTCTACCGGTGGCCGCGGAGCGCACCGCTGCTGCTATTGCCCGAACTTTAGCGTGA

Upstream 100 bases:

>100_bases
GCGGCTATTCCGATCCGGCCGGGACGCACTTTGCACAACTCATAGCACCACTTGGGCACTGAGCCGGATCCCAAACTGAG
TCGGACGGTAGCCTGACACA

Downstream 100 bases:

>100_bases
TGATTCCGTCCCGGTTTACTCCGGCACCTGCTGGCGGGTTTTGATATGCCACCCGGTTGTGCTGGGAGCCACCAGCATCC
ACATCGGGGCCTTTATCCAG

Product: para-aminobenzoate synthase component II

Products: NA

Alternate protein names: Anthranilate synthase component II; Glutamine amido-transferase [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MRILVIDNYDSFVFNLVQYLGQLGVDAEVWRNDDTRLSDESTIAAQFDGILLSPGPGTPERAGASINLVRVCAAAHTPLL
GVCLGHQAIGVSFGATVDRAPELLHGKTSSVFHTNNGVLQGLPNPFTATRYHSLTILPESLPPVLEVVARTRSGVIMAVR
HTELPIHGVQFHPESILTEGGHRLLANWLTYCGWLCDDALIRRLENEVDAAVHPRLPVAAERTAAAIARTLA

Sequences:

>Translated_232_residues
MRILVIDNYDSFVFNLVQYLGQLGVDAEVWRNDDTRLSDESTIAAQFDGILLSPGPGTPERAGASINLVRVCAAAHTPLL
GVCLGHQAIGVSFGATVDRAPELLHGKTSSVFHTNNGVLQGLPNPFTATRYHSLTILPESLPPVLEVVARTRSGVIMAVR
HTELPIHGVQFHPESILTEGGHRLLANWLTYCGWLCDDALIRRLENEVDAAVHPRLPVAAERTAAAIARTLA
>Mature_232_residues
MRILVIDNYDSFVFNLVQYLGQLGVDAEVWRNDDTRLSDESTIAAQFDGILLSPGPGTPERAGASINLVRVCAAAHTPLL
GVCLGHQAIGVSFGATVDRAPELLHGKTSSVFHTNNGVLQGLPNPFTATRYHSLTILPESLPPVLEVVARTRSGVIMAVR
HTELPIHGVQFHPESILTEGGHRLLANWLTYCGWLCDDALIRRLENEVDAAVHPRLPVAAERTAAAIARTLA

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=187, Percent_Identity=51.8716577540107, Blast_Score=194, Evalue=5e-51,
Organism=Escherichia coli, GI1787517, Length=191, Percent_Identity=40.8376963350785, Blast_Score=129, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6322638, Length=192, Percent_Identity=43.2291666666667, Blast_Score=162, Evalue=6e-41,
Organism=Saccharomyces cerevisiae, GI6324361, Length=211, Percent_Identity=30.8056872037915, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324878, Length=171, Percent_Identity=29.2397660818713, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 25092; Mature: 25092

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVIDNYDSFVFNLVQYLGQLGVDAEVWRNDDTRLSDESTIAAQFDGILLSPGPGTPE
CEEEEEECCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCEEEEEECCEEECCCCCCHH
RAGASINLVRVCAAAHTPLLGVCLGHQAIGVSFGATVDRAPELLHGKTSSVFHTNNGVLQ
HCCCCHHHHHHHHHHCCCHHHHHHCCHHHCEECCCCHHCCHHHHCCCCCCEEECCCCEEE
GLPNPFTATRYHSLTILPESLPPVLEVVARTRSGVIMAVRHTELPIHGVQFHPESILTEG
CCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCEEECHHHHHHCC
GHRLLANWLTYCGWLCDDALIRRLENEVDAAVHPRLPVAAERTAAAIARTLA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MRILVIDNYDSFVFNLVQYLGQLGVDAEVWRNDDTRLSDESTIAAQFDGILLSPGPGTPE
CEEEEEECCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCEEEEEECCEEECCCCCCHH
RAGASINLVRVCAAAHTPLLGVCLGHQAIGVSFGATVDRAPELLHGKTSSVFHTNNGVLQ
HCCCCHHHHHHHHHHCCCHHHHHHCCHHHCEECCCCHHCCHHHHCCCCCCEEECCCCEEE
GLPNPFTATRYHSLTILPESLPPVLEVVARTRSGVIMAVRHTELPIHGVQFHPESILTEG
CCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCEEECHHHHHHCC
GHRLLANWLTYCGWLCDDALIRRLENEVDAAVHPRLPVAAERTAAAIARTLA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]