Click here to switch to the map view.

The map label for this gene is udg [H]

Identifier: 220919539

GI number: 220919539

Start: 4966347

End: 4967657

Strand: Direct

Name: udg [H]

Synonym: A2cp1_4460

Alternate gene names: 220919539

Gene position: 4966347-4967657 (Clockwise)

Preceding gene: 220919538

Following gene: 220919545

Centisome position: 98.75

GC content: 72.16

Gene sequence:

>1311_bases
ATGAACATCACCGTCGTCGGCACCGGCTACGTGGGCCTCGTCACCGGCACCTGCTTCGCGGAGTCGGGCCACCGGGTCAC
CTGCCTCGACCTCGACGCCGCCAAGATCGAGACGCTCCGCGGCGGCGGGATCCCCATCTACGAGCCCGGCCTCGAGGAGC
TGGTGCGCCGCAACGTGAAGGAGCGGCGCCTGTCCTTCACCACCTCCTACCCGGAGGCCATGAAGGACGCCGACGTGGCG
TTCATCGCGGTGGGCACCCCGCCCGGCGAGAACGGCGACGCCGACCTGTCGTACGTGCTCGCCGCCGCCCGCGAGATCGG
CCGGCACCTCACCCGCTACACGGTGGTGGTGGACAAGAGCACGGTGCCGGTGGGCAGCGCCGACAAGGTGGCCGAGGCGC
TCCGCGAGGTGACCACGCAGCCGTTCGACGTGGTCTCCAACCCCGAGTTCCTGAAGGAAGGGGCCGCCATCGACGACTTC
ATGCGGCCGGACCGGGTGGTGGTGGGCGTCGCCTCCGAGCGCGCCCGCGCGGTGATGGCCGAGCTGTACGCGCCGTTCGT
CCGCGCCGAGCAGCCGGTGCTGTTCATGGACCTGCGCTCGGCCGAGCTGACCAAGTACGCGGCGAACGCGATGCTGGCGA
CGCGCATCTCGTTCATGAACGAGATCGCCACGCTGTGCGAGAAGCTGGGCGCGGACGTGGACCAGGTCCGCCGCGGCATC
GGCTCCGACCGGCGCATCGGCCACCCGTTCCTGTTCCCCGGGGTGGGCTTCGGCGGCTCCTGCTTCCCGAAGGACGTGCG
CGCGGTGATGAGCATGGCGCGCCACCTGGGCCTCGACTTCGACCTGCTCCGCGCGGTGGAGCGCGTGAACGAGCGGCAGA
AGCGCTGGCTGGTGGAGAAGGCGCACAAGCACTTCGGCACGCTGGCCGGGCGCACCTTCGGCGTGTGGGGGCTCGCGTTC
AAGCCGCGCACCGACGACATGCGCGAGGCGCCGGCCATCACCGTGATCGAGGGCCTGCTCGCGGCCGGCGCCCGGGTCCG
CGCCCACGATCCGGTGGCCGCCCAGGTGGCGGACGGCATCTTCCGCGGCCGCGGCGTGACGCTGGTGGACGAGCCGTACG
CCGCCGCCGAGGGCGCCGACGCGCTCCTGCTCGTGACCGAGTGGAACGAGTTCCGCCAGCCCGACCTGGCGCGCCTGAAG
CAGCTCATGGCGCAGCCGGTGCTGTTCGACGGCCGGAACGTGTGGGACGCCGCCAAGGTCCGCGCGGCCGGGTTCACCTA
CTACGGCGTGGGGCGGGCGGCGGAGTCGTAG

Upstream 100 bases:

>100_bases
CGGCGAGGACGCCGCGGCGCGCCTCGTGGTCGCGCCGTGATCGGCCCGGGCGGGGCGTGCTAGATTGCGCCCCTCTGCTT
TCCGTGAGGGACCGCTCGCA

Downstream 100 bases:

>100_bases
GTCCCTCGACTCCGGCCGTGCCTCGCTCGGGATGAGCGATCCGCTCACCCTGAGCGTAGGCGAGCCGGAGGCTCGCCGGA
GTCGAAGGGTCGGGATGAGC

Product: nucleotide sugar dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MNITVVGTGYVGLVTGTCFAESGHRVTCLDLDAAKIETLRGGGIPIYEPGLEELVRRNVKERRLSFTTSYPEAMKDADVA
FIAVGTPPGENGDADLSYVLAAAREIGRHLTRYTVVVDKSTVPVGSADKVAEALREVTTQPFDVVSNPEFLKEGAAIDDF
MRPDRVVVGVASERARAVMAELYAPFVRAEQPVLFMDLRSAELTKYAANAMLATRISFMNEIATLCEKLGADVDQVRRGI
GSDRRIGHPFLFPGVGFGGSCFPKDVRAVMSMARHLGLDFDLLRAVERVNERQKRWLVEKAHKHFGTLAGRTFGVWGLAF
KPRTDDMREAPAITVIEGLLAAGARVRAHDPVAAQVADGIFRGRGVTLVDEPYAAAEGADALLLVTEWNEFRQPDLARLK
QLMAQPVLFDGRNVWDAAKVRAAGFTYYGVGRAAES

Sequences:

>Translated_436_residues
MNITVVGTGYVGLVTGTCFAESGHRVTCLDLDAAKIETLRGGGIPIYEPGLEELVRRNVKERRLSFTTSYPEAMKDADVA
FIAVGTPPGENGDADLSYVLAAAREIGRHLTRYTVVVDKSTVPVGSADKVAEALREVTTQPFDVVSNPEFLKEGAAIDDF
MRPDRVVVGVASERARAVMAELYAPFVRAEQPVLFMDLRSAELTKYAANAMLATRISFMNEIATLCEKLGADVDQVRRGI
GSDRRIGHPFLFPGVGFGGSCFPKDVRAVMSMARHLGLDFDLLRAVERVNERQKRWLVEKAHKHFGTLAGRTFGVWGLAF
KPRTDDMREAPAITVIEGLLAAGARVRAHDPVAAQVADGIFRGRGVTLVDEPYAAAEGADALLLVTEWNEFRQPDLARLK
QLMAQPVLFDGRNVWDAAKVRAAGFTYYGVGRAAES
>Mature_436_residues
MNITVVGTGYVGLVTGTCFAESGHRVTCLDLDAAKIETLRGGGIPIYEPGLEELVRRNVKERRLSFTTSYPEAMKDADVA
FIAVGTPPGENGDADLSYVLAAAREIGRHLTRYTVVVDKSTVPVGSADKVAEALREVTTQPFDVVSNPEFLKEGAAIDDF
MRPDRVVVGVASERARAVMAELYAPFVRAEQPVLFMDLRSAELTKYAANAMLATRISFMNEIATLCEKLGADVDQVRRGI
GSDRRIGHPFLFPGVGFGGSCFPKDVRAVMSMARHLGLDFDLLRAVERVNERQKRWLVEKAHKHFGTLAGRTFGVWGLAF
KPRTDDMREAPAITVIEGLLAAGARVRAHDPVAAQVADGIFRGRGVTLVDEPYAAAEGADALLLVTEWNEFRQPDLARLK
QLMAQPVLFDGRNVWDAAKVRAAGFTYYGVGRAAES

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=469, Percent_Identity=36.6737739872068, Blast_Score=268, Evalue=8e-72,
Organism=Homo sapiens, GI296040438, Length=376, Percent_Identity=36.7021276595745, Blast_Score=215, Evalue=6e-56,
Organism=Homo sapiens, GI296040443, Length=330, Percent_Identity=35.7575757575758, Blast_Score=191, Evalue=2e-48,
Organism=Escherichia coli, GI1788340, Length=368, Percent_Identity=30.1630434782609, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI48994968, Length=437, Percent_Identity=28.604118993135, Blast_Score=148, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI17560350, Length=462, Percent_Identity=36.3636363636364, Blast_Score=271, Evalue=6e-73,
Organism=Drosophila melanogaster, GI17136908, Length=462, Percent_Identity=36.7965367965368, Blast_Score=272, Evalue=3e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 47530; Mature: 47530

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNITVVGTGYVGLVTGTCFAESGHRVTCLDLDAAKIETLRGGGIPIYEPGLEELVRRNVK
CEEEEEECCEEEEHHHHEEECCCCEEEEEECCHHHHHHHCCCCCCCCCCCHHHHHHHHHH
ERRLSFTTSYPEAMKDADVAFIAVGTPPGENGDADLSYVLAAAREIGRHLTRYTVVVDKS
HHHHHHCCCCHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEECC
TVPVGSADKVAEALREVTTQPFDVVSNPEFLKEGAAIDDFMRPDRVVVGVASERARAVMA
CCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHCCCCEEEEEECHHHHHHHHH
ELYAPFVRAEQPVLFMDLRSAELTKYAANAMLATRISFMNEIATLCEKLGADVDQVRRGI
HHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCC
GSDRRIGHPFLFPGVGFGGSCFPKDVRAVMSMARHLGLDFDLLRAVERVNERQKRWLVEK
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
AHKHFGTLAGRTFGVWGLAFKPRTDDMREAPAITVIEGLLAAGARVRAHDPVAAQVADGI
HHHHHHHHCCCCEEEEEEEECCCCCCHHHCCHHHHHHHHHHCCCEEECCCCHHHHHHHHH
FRGRGVTLVDEPYAAAEGADALLLVTEWNEFRQPDLARLKQLMAQPVLFDGRNVWDAAKV
HCCCCEEEECCCCCCCCCCCEEEEEECCHHHCCCHHHHHHHHHHCCEEECCCCCHHHHHH
RAAGFTYYGVGRAAES
HHCCEEEEECCCCCCC
>Mature Secondary Structure
MNITVVGTGYVGLVTGTCFAESGHRVTCLDLDAAKIETLRGGGIPIYEPGLEELVRRNVK
CEEEEEECCEEEEHHHHEEECCCCEEEEEECCHHHHHHHCCCCCCCCCCCHHHHHHHHHH
ERRLSFTTSYPEAMKDADVAFIAVGTPPGENGDADLSYVLAAAREIGRHLTRYTVVVDKS
HHHHHHCCCCHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEECC
TVPVGSADKVAEALREVTTQPFDVVSNPEFLKEGAAIDDFMRPDRVVVGVASERARAVMA
CCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHCCCCEEEEEECHHHHHHHHH
ELYAPFVRAEQPVLFMDLRSAELTKYAANAMLATRISFMNEIATLCEKLGADVDQVRRGI
HHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCC
GSDRRIGHPFLFPGVGFGGSCFPKDVRAVMSMARHLGLDFDLLRAVERVNERQKRWLVEK
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
AHKHFGTLAGRTFGVWGLAFKPRTDDMREAPAITVIEGLLAAGARVRAHDPVAAQVADGI
HHHHHHHHCCCCEEEEEEEECCCCCCHHHCCHHHHHHHHHHCCCEEECCCCHHHHHHHHH
FRGRGVTLVDEPYAAAEGADALLLVTEWNEFRQPDLARLKQLMAQPVLFDGRNVWDAAKV
HCCCCEEEECCCCCCCCCCCEEEEEECCHHHCCCHHHHHHHHHHCCEEECCCCCHHHHHH
RAAGFTYYGVGRAAES
HHCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]