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The map label for this gene is pit [H]

Identifier: 220919463

GI number: 220919463

Start: 4879503

End: 4880561

Strand: Direct

Name: pit [H]

Synonym: A2cp1_4384

Alternate gene names: 220919463

Gene position: 4879503-4880561 (Clockwise)

Preceding gene: 220919462

Following gene: 220919465

Centisome position: 97.02

GC content: 69.41

Gene sequence:

>1059_bases
ATGCTCATCCTCGTCATCCTCCTCGTCCTGGTCGCGCTCGCCTTCGACTTCATCAACGGGTTCCACGACGCCGCGAACTC
CATCGCGACCGTGGTCTCGACCCGGGTGCTCTCGCCGCTCGTCGCGGTGGCCTGGGCGGCGTTCTTCAACTTCATCTCCG
CCATGCCGGTGCTGTGGGGCGCGGAGCTGAAGGTGGCCGCCACCATGGGCAAGGGCATCGTCCACTTCGAGCAGCTCAAG
GCGGGCGGCATCTCGCTCGTGCTCATGGTGGTGTTCGCCGCGCTGATGGGCGCGATCGTCTGGAACCTGCTGACCTGGTG
GTGGGGGCTGCCCTCGTCCTCCTCGCACGCGCTCGCCGGCGGCATGATCGGCGCGAGCCTGCCGCCGCTCGGCTTCGCCG
GCCTCATCCCCTCCGGCATCCTCAAGATCGTCGCGTTCATCGTGCTCTCGCCGCTCATCGGCATGGTGCTCGGCTCGCTC
ATGATGGTGGCGACGGCCTGGATCGTGCGGAAGAACACGCCGGCGCGCGTGGATCGCTGGTTCCGGCGCCTGCAGCTCGT
CTCGGCCGCGATCTTCAGCTACAGCCACGGCACGAACGACGCCCAGAAGGTGATGGGCATCATCTCGGTCATCCTCTACG
GCACCATCTGGGCGGACCGCGCCGCGATGACGCCGGGGCACTTCCCGGTGCCGTTCTGGGTGGTGCTCTCCTGCCACGCG
GCCATCGGCCTCGGGACCATGTTCGGCGGCTGGCGCATCGTCCGCACCATGGGCCACAACCTCACCAAGCTGCAGCCCAT
CGGCGGCTTCTGCGCCGAGACCGGCGGCGGCGTGACCATCCTCGCGCTCGCCCACTTCGGCATCCCGGTCTCCACCACGC
ACACCATCACCGGGGCGATCGTGGGCGTGGGCTCGACGAAGGGCACGCGCGCGGTGCGCTGGGGCGTGGCCGGCCGGATC
ATCTGGGCCTGGGTGTTCACCATCCCGGCCGCGGCGATCGTCGCCGGCGTCATCTTCCTGGTGACGCGCGCGATCGTGGG
CGTGGTCGGCGTCGGCTGA

Upstream 100 bases:

>100_bases
GCGACCGACCGGGCCGAGGACGTGGCGAACGTGATCGAGGGCGTGGTGCTGGAGCACGCCTAGACGATCCCACCCTCCCC
GCCGCGCCCGGTCCGCCGCC

Downstream 100 bases:

>100_bases
CGATCAGTCGCCGCGCCGCCGCGAGGCCAGCATCCCGCAGGCGGCGTGCTCGTCCTGGCCGCCGGAGTAGCGGCGCACGA
CGGGCGTGCCGGGCAGCTCG

Product: phosphate transporter

Products: Proton [Cytoplasm]; phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MLILVILLVLVALAFDFINGFHDAANSIATVVSTRVLSPLVAVAWAAFFNFISAMPVLWGAELKVAATMGKGIVHFEQLK
AGGISLVLMVVFAALMGAIVWNLLTWWWGLPSSSSHALAGGMIGASLPPLGFAGLIPSGILKIVAFIVLSPLIGMVLGSL
MMVATAWIVRKNTPARVDRWFRRLQLVSAAIFSYSHGTNDAQKVMGIISVILYGTIWADRAAMTPGHFPVPFWVVLSCHA
AIGLGTMFGGWRIVRTMGHNLTKLQPIGGFCAETGGGVTILALAHFGIPVSTTHTITGAIVGVGSTKGTRAVRWGVAGRI
IWAWVFTIPAAAIVAGVIFLVTRAIVGVVGVG

Sequences:

>Translated_352_residues
MLILVILLVLVALAFDFINGFHDAANSIATVVSTRVLSPLVAVAWAAFFNFISAMPVLWGAELKVAATMGKGIVHFEQLK
AGGISLVLMVVFAALMGAIVWNLLTWWWGLPSSSSHALAGGMIGASLPPLGFAGLIPSGILKIVAFIVLSPLIGMVLGSL
MMVATAWIVRKNTPARVDRWFRRLQLVSAAIFSYSHGTNDAQKVMGIISVILYGTIWADRAAMTPGHFPVPFWVVLSCHA
AIGLGTMFGGWRIVRTMGHNLTKLQPIGGFCAETGGGVTILALAHFGIPVSTTHTITGAIVGVGSTKGTRAVRWGVAGRI
IWAWVFTIPAAAIVAGVIFLVTRAIVGVVGVG
>Mature_352_residues
MLILVILLVLVALAFDFINGFHDAANSIATVVSTRVLSPLVAVAWAAFFNFISAMPVLWGAELKVAATMGKGIVHFEQLK
AGGISLVLMVVFAALMGAIVWNLLTWWWGLPSSSSHALAGGMIGASLPPLGFAGLIPSGILKIVAFIVLSPLIGMVLGSL
MMVATAWIVRKNTPARVDRWFRRLQLVSAAIFSYSHGTNDAQKVMGIISVILYGTIWADRAAMTPGHFPVPFWVVLSCHA
AIGLGTMFGGWRIVRTMGHNLTKLQPIGGFCAETGGGVTILALAHFGIPVSTTHTITGAIVGVGSTKGTRAVRWGVAGRI
IWAWVFTIPAAAIVAGVIFLVTRAIVGVVGVG

Specific function: Low-affinity inorganic phosphate transport (Probable) [H]

COG id: COG0306

COG function: function code P; Phosphate/sulphate permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. Pit subfamily [H]

Homologues:

Organism=Homo sapiens, GI31543630, Length=188, Percent_Identity=28.1914893617021, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI5803173, Length=160, Percent_Identity=30.625, Blast_Score=79, Evalue=8e-15,
Organism=Escherichia coli, GI1789360, Length=227, Percent_Identity=37.0044052863436, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789907, Length=227, Percent_Identity=37.0044052863436, Blast_Score=107, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17539280, Length=167, Percent_Identity=31.1377245508982, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI25146401, Length=175, Percent_Identity=27.4285714285714, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71981576, Length=186, Percent_Identity=29.0322580645161, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI32566716, Length=159, Percent_Identity=31.4465408805031, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17536725, Length=177, Percent_Identity=25.4237288135593, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17557328, Length=153, Percent_Identity=31.3725490196078, Blast_Score=74, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6319773, Length=164, Percent_Identity=30.4878048780488, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356511, Length=206, Percent_Identity=27.1844660194175, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001204 [H]

Pfam domain/function: PF01384 PHO4 [H]

EC number: NA

Molecular weight: Translated: 37059; Mature: 37059

Theoretical pI: Translated: 11.54; Mature: 11.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLILVILLVLVALAFDFINGFHDAANSIATVVSTRVLSPLVAVAWAAFFNFISAMPVLWG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AELKVAATMGKGIVHFEQLKAGGISLVLMVVFAALMGAIVWNLLTWWWGLPSSSSHALAG
CCCEEHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHC
GMIGASLPPLGFAGLIPSGILKIVAFIVLSPLIGMVLGSLMMVATAWIVRKNTPARVDRW
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
FRRLQLVSAAIFSYSHGTNDAQKVMGIISVILYGTIWADRAAMTPGHFPVPFWVVLSCHA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
AIGLGTMFGGWRIVRTMGHNLTKLQPIGGFCAETGGGVTILALAHFGIPVSTTHTITGAI
HHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHCCCCCEEEEEHHHCCCCCCCCHHHHHHE
VGVGSTKGTRAVRWGVAGRIIWAWVFTIPAAAIVAGVIFLVTRAIVGVVGVG
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLILVILLVLVALAFDFINGFHDAANSIATVVSTRVLSPLVAVAWAAFFNFISAMPVLWG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AELKVAATMGKGIVHFEQLKAGGISLVLMVVFAALMGAIVWNLLTWWWGLPSSSSHALAG
CCCEEHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHC
GMIGASLPPLGFAGLIPSGILKIVAFIVLSPLIGMVLGSLMMVATAWIVRKNTPARVDRW
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
FRRLQLVSAAIFSYSHGTNDAQKVMGIISVILYGTIWADRAAMTPGHFPVPFWVVLSCHA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
AIGLGTMFGGWRIVRTMGHNLTKLQPIGGFCAETGGGVTILALAHFGIPVSTTHTITGAI
HHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHCCCCCEEEEEHHHCCCCCCCCHHHHHHE
VGVGSTKGTRAVRWGVAGRIIWAWVFTIPAAAIVAGVIFLVTRAIVGVVGVG
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + phosphate [Periplasm] = Proton [Cytoplasm] + phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9696772; 11481430 [H]