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The map label for this gene is nudL [H]

Identifier: 220919343

GI number: 220919343

Start: 4748575

End: 4749234

Strand: Direct

Name: nudL [H]

Synonym: A2cp1_4264

Alternate gene names: 220919343

Gene position: 4748575-4749234 (Clockwise)

Preceding gene: 220919341

Following gene: 220919344

Centisome position: 94.42

GC content: 78.33

Gene sequence:

>660_bases
ATGCGTGCCCCCGGCTTCGACGAGGCGACCGAGCGCGTGCGCCGTGCGCTCGCCGCGCGGCCGCGGCGGGCGCTCGCGGT
GCCCGGCTTCCGGGCGGCGGCGGTGCTGGTCGCGCTGCTCGACCGCGCCGGCGGCCCCTCGATCCTGTTCACCCGCCGTT
CACAGGCGCTCGAGCACCACCGCGGCGAGATCTCCTTCCCGGGGGGGCGGCTCGAGCCCGGAGAGGACGCCGCGGCCGCC
GCGCTGCGCGAGGCGCACGAGGAGGTGGGCCTGGCGCCGGCCGCGTCCGAGGTGCTCGGCCTCCTCGACGACCTGCCCAG
CGTGGCCGGGTACGTGGTGACGCCGGTCGCCGCCTCGGTGCGCGCGCCGCCCGGCGCGTTCACCGCCTCCGCCGGCGAGG
TGGACGAGCACTTCGAGCTGCCACTGGCGCAGCTCCTCGATCCGGCGCTGCGGCGCGCCTCGCTGTGGGATCCCGCCGGC
CTCCCGGAGCGGCTCGCGGCGGTGGTGGCGCGCGCGGCGGTGCCGTTCGAGGACGTGGACCCGGGGACGGGACACTGGCG
GGTGTGGTCGTTCCACGCGGACGAGGCGCGGGTGGTCTGGGGCCTGACGGCCCGCATCCTGGCGGATCTCCTCGATCGGG
CCTTCGTCGCGCGGGGGTGA

Upstream 100 bases:

>100_bases
GTGGAAAGCAATCGGCCGCGGCGCGCGCCGTCGCGGCGGACGGGCGGGCGTCCCCCTCGCCGCCCGGCGCGCCGGCGCGC
GTCGCGTTAGATGGAGGACG

Downstream 100 bases:

>100_bases
TGGCCGGGGGGCACCCGCGTCGGGGGGGCCCGTCGCGCGCGGGGATGGGCGGGCTTACCATCCCGGCGTGAGCCGCACGC
GCGCCGCCCTGCTCGTCGCG

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MRAPGFDEATERVRRALAARPRRALAVPGFRAAAVLVALLDRAGGPSILFTRRSQALEHHRGEISFPGGRLEPGEDAAAA
ALREAHEEVGLAPAASEVLGLLDDLPSVAGYVVTPVAASVRAPPGAFTASAGEVDEHFELPLAQLLDPALRRASLWDPAG
LPERLAAVVARAAVPFEDVDPGTGHWRVWSFHADEARVVWGLTARILADLLDRAFVARG

Sequences:

>Translated_219_residues
MRAPGFDEATERVRRALAARPRRALAVPGFRAAAVLVALLDRAGGPSILFTRRSQALEHHRGEISFPGGRLEPGEDAAAA
ALREAHEEVGLAPAASEVLGLLDDLPSVAGYVVTPVAASVRAPPGAFTASAGEVDEHFELPLAQLLDPALRRASLWDPAG
LPERLAAVVARAAVPFEDVDPGTGHWRVWSFHADEARVVWGLTARILADLLDRAFVARG
>Mature_219_residues
MRAPGFDEATERVRRALAARPRRALAVPGFRAAAVLVALLDRAGGPSILFTRRSQALEHHRGEISFPGGRLEPGEDAAAA
ALREAHEEVGLAPAASEVLGLLDDLPSVAGYVVTPVAASVRAPPGAFTASAGEVDEHFELPLAQLLDPALRRASLWDPAG
LPERLAAVVARAAVPFEDVDPGTGHWRVWSFHADEARVVWGLTARILADLLDRAFVARG

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=127, Percent_Identity=36.2204724409449, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI32469515, Length=115, Percent_Identity=42.6086956521739, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1788115, Length=192, Percent_Identity=37.5, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17536993, Length=177, Percent_Identity=29.3785310734463, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17510677, Length=133, Percent_Identity=36.8421052631579, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 23232; Mature: 23232

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAPGFDEATERVRRALAARPRRALAVPGFRAAAVLVALLDRAGGPSILFTRRSQALEHH
CCCCCCCHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHH
RGEISFPGGRLEPGEDAAAAALREAHEEVGLAPAASEVLGLLDDLPSVAGYVVTPVAASV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAPPGAFTASAGEVDEHFELPLAQLLDPALRRASLWDPAGLPERLAAVVARAAVPFEDVD
CCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCC
PGTGHWRVWSFHADEARVVWGLTARILADLLDRAFVARG
CCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRAPGFDEATERVRRALAARPRRALAVPGFRAAAVLVALLDRAGGPSILFTRRSQALEHH
CCCCCCCHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHH
RGEISFPGGRLEPGEDAAAAALREAHEEVGLAPAASEVLGLLDDLPSVAGYVVTPVAASV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAPPGAFTASAGEVDEHFELPLAQLLDPALRRASLWDPAGLPERLAAVVARAAVPFEDVD
CCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCC
PGTGHWRVWSFHADEARVVWGLTARILADLLDRAFVARG
CCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA