Click here to switch to the map view.

The map label for this gene is queF

Identifier: 220919323

GI number: 220919323

Start: 4725796

End: 4726164

Strand: Direct

Name: queF

Synonym: A2cp1_4244

Alternate gene names: 220919323

Gene position: 4725796-4726164 (Clockwise)

Preceding gene: 220919321

Following gene: 220919324

Centisome position: 93.96

GC content: 70.19

Gene sequence:

>369_bases
ATGCCGACCCAGCCCTCCCGCGACCTCCAGACGTTCCCGAACCCGAAGCCCGGACGCCCGTTCGAGATCGCGATGGAGTG
CCCGGAGTTCACCTGCGTGTGCCCGATGACCGGGCAGCCGGACTTCGCCACCATCCGCCTCCGCTACGTCCCGGCCGAGC
GCTGCGTGGAGCTGAAGAGCCTGAAGCTGTACCTGTGGAGCTTCCGGAACGAGGGCACGTTCCACGAGGCGGTGACGAAC
CGCATCTGTGACGACCTCGTGGCTGCCCTCGCGCCCCGCTGGATCGAGGTCGTGGGCGACTTCGCCGTCCGCGGCGGCAT
CCACACGGTGGTGACCGCCCGCCACGGCGAGCGCCCCGCCGGAGTCTGA

Upstream 100 bases:

>100_bases
GACCCCACCCCGACCGGTAAGGATTTCAGCCCGGCCCGCGAAATCCCGACAGCATGCTGTCGGTTTTCCACCGGTTCGCA
CCAAGCCCGAAGGACGCCTC

Downstream 100 bases:

>100_bases
GCGCGCTCGACAGCGCCCGAGCGGGCGTGCGCGCGCCCCTGTCAGGCTTCCCCTTCACCCCCTCGCACTTCACCTTGAGG
TCCGGGGAGGGGAGGGTGGA

Product: 7-cyano-7-deazaguanine reductase

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine reductase; NADPH-dependent nitrile oxidoreductase; PreQ(0) reductase

Number of amino acids: Translated: 122; Mature: 121

Protein sequence:

>122_residues
MPTQPSRDLQTFPNPKPGRPFEIAMECPEFTCVCPMTGQPDFATIRLRYVPAERCVELKSLKLYLWSFRNEGTFHEAVTN
RICDDLVAALAPRWIEVVGDFAVRGGIHTVVTARHGERPAGV

Sequences:

>Translated_122_residues
MPTQPSRDLQTFPNPKPGRPFEIAMECPEFTCVCPMTGQPDFATIRLRYVPAERCVELKSLKLYLWSFRNEGTFHEAVTN
RICDDLVAALAPRWIEVVGDFAVRGGIHTVVTARHGERPAGV
>Mature_121_residues
PTQPSRDLQTFPNPKPGRPFEIAMECPEFTCVCPMTGQPDFATIRLRYVPAERCVELKSLKLYLWSFRNEGTFHEAVTNR
ICDDLVAALAPRWIEVVGDFAVRGGIHTVVTARHGERPAGV

Specific function: Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)

COG id: COG0780

COG function: function code R; Enzyme related to GTP cyclohydrolase I

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEF_ANAD2 (B8JAR2)

Other databases:

- EMBL:   CP001359
- RefSeq:   YP_002494627.1
- ProteinModelPortal:   B8JAR2
- SMR:   B8JAR2
- GeneID:   7298319
- GenomeReviews:   CP001359_GR
- KEGG:   acp:A2cp1_4244
- HOGENOM:   HBG294103
- ProtClustDB:   PRK13258
- GO:   GO:0005737
- HAMAP:   MF_00818
- InterPro:   IPR016856
- InterPro:   IPR020602
- PIRSF:   PIRSF027377
- TIGRFAMs:   TIGR03139

Pfam domain/function: PF01227 GTP_cyclohydroI

EC number: =1.7.1.13

Molecular weight: Translated: 13700; Mature: 13569

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTQPSRDLQTFPNPKPGRPFEIAMECPEFTCVCPMTGQPDFATIRLRYVPAERCVELKS
CCCCCCCCCCCCCCCCCCCCEEEEEECCCEEEECCCCCCCCEEEEEEEECCHHHHHHHHH
LKLYLWSFRNEGTFHEAVTNRICDDLVAALAPRWIEVVGDFAVRGGIHTVVTARHGERPA
HEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCC
GV
CC
>Mature Secondary Structure 
PTQPSRDLQTFPNPKPGRPFEIAMECPEFTCVCPMTGQPDFATIRLRYVPAERCVELKS
CCCCCCCCCCCCCCCCCCCEEEEEECCCEEEECCCCCCCCEEEEEEEECCHHHHHHHHH
LKLYLWSFRNEGTFHEAVTNRICDDLVAALAPRWIEVVGDFAVRGGIHTVVTARHGERPA
HEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCC
GV
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA