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The map label for this gene is trxB [H]

Identifier: 220919174

GI number: 220919174

Start: 4578211

End: 4579155

Strand: Direct

Name: trxB [H]

Synonym: A2cp1_4094

Alternate gene names: 220919174

Gene position: 4578211-4579155 (Clockwise)

Preceding gene: 220919171

Following gene: 220919175

Centisome position: 91.03

GC content: 70.05

Gene sequence:

>945_bases
ATGTCCAAGCACGAGCGGCTCGTCATCGTCGGCAGCGGTCCCGCGGGCTACACCGCGGCGCTCTACGCCGCGCGCGCCAA
CCTCCAGCCGCTGCTGTTCGAGGGCATGCAGCCGGGCGGGCAGCTGACCATCACGAGCGAGGTGGAGAACTTCCCCGGCT
TCCCCGAGGGCATCCTCGGGCCGGAGCTGATGGAGAAGATGAAGAAGCAGGCCGAGCGCTTCGGCACGCGCTTCGAGGCG
AGCGAGATCACGCGGGTGGACTTCTCCCAGCGCCCGTTCAAGCTCTGGCAGGACGACACGCTCTACACCGCCGACGCGGT
GATCGTCGCCACCGGCGCCTCCGCCAAGTGGCTGCAGATCCCGTCGGAGAAGCAGTACCAGGGGCGCGGCGTGTCGGCCT
GCGCCACCTGCGACGGCTTCTTCTTCCGCGGGGTGGAGATCGCGGTGGTGGGCGGCGGCGACACGGCGCTGGAGGAGGCG
AGCTTCCTCACCAAGTACGCGAGCAAGGTGCACGTGGTGCACCGCCGCGGCGAGCTGCGCGCCTCCAAGATCATGCAGGA
CCGCGCCCGCAAGAACCCGAAGATCGAGCTGGTGCTGAACGCGGTGGTGGACGAGATCCTCGGCGACGGCAAGGCCGTCA
CCGGCGTCCGGCTCAAGGACACCCGCGACGGCTCGACCCGCGAGCTGCCGCTGAAGGGCGTGTTCATGGGCATCGGCCAC
GAGCCGAACACCGGCATCTTCAAGGGCCAGCTCGAGATGAACGAGGTGGGCTACCTCGCCGTGAAGGCGCCCTCCACCGC
CACCAGCGTGCCGGGCGTGTTCGCGGCCGGCGACGTGTCGGACCCGCACTACCGCCAGGCGATCAGCGCGGCCGGGACCG
GCTGCTCCGCCGCCATCGACGCGGAGCGCTGGCTGGGCGAGCACGTCACCGAGAGCTGGAACTAG

Upstream 100 bases:

>100_bases
GGCGCCCCCTCGCCCGGGCGATGCGCGGGCGAACCTTCGCCGTGACACGCTGGCTCCAAGCGGCTATTCAGAGGTCCCCT
CGCACCTGGGAGGTCACGCC

Downstream 100 bases:

>100_bases
CCATGAAGATGATCGACGTCGGCGCGAAGCCGAAGACCGAGCGCGTGGCCGTGGCGCACGGCTTCGTGGCGATGTCCGCC
GACACGGTGGGCAGGATCCG

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MSKHERLVIVGSGPAGYTAALYAARANLQPLLFEGMQPGGQLTITSEVENFPGFPEGILGPELMEKMKKQAERFGTRFEA
SEITRVDFSQRPFKLWQDDTLYTADAVIVATGASAKWLQIPSEKQYQGRGVSACATCDGFFFRGVEIAVVGGGDTALEEA
SFLTKYASKVHVVHRRGELRASKIMQDRARKNPKIELVLNAVVDEILGDGKAVTGVRLKDTRDGSTRELPLKGVFMGIGH
EPNTGIFKGQLEMNEVGYLAVKAPSTATSVPGVFAAGDVSDPHYRQAISAAGTGCSAAIDAERWLGEHVTESWN

Sequences:

>Translated_314_residues
MSKHERLVIVGSGPAGYTAALYAARANLQPLLFEGMQPGGQLTITSEVENFPGFPEGILGPELMEKMKKQAERFGTRFEA
SEITRVDFSQRPFKLWQDDTLYTADAVIVATGASAKWLQIPSEKQYQGRGVSACATCDGFFFRGVEIAVVGGGDTALEEA
SFLTKYASKVHVVHRRGELRASKIMQDRARKNPKIELVLNAVVDEILGDGKAVTGVRLKDTRDGSTRELPLKGVFMGIGH
EPNTGIFKGQLEMNEVGYLAVKAPSTATSVPGVFAAGDVSDPHYRQAISAAGTGCSAAIDAERWLGEHVTESWN
>Mature_313_residues
SKHERLVIVGSGPAGYTAALYAARANLQPLLFEGMQPGGQLTITSEVENFPGFPEGILGPELMEKMKKQAERFGTRFEAS
EITRVDFSQRPFKLWQDDTLYTADAVIVATGASAKWLQIPSEKQYQGRGVSACATCDGFFFRGVEIAVVGGGDTALEEAS
FLTKYASKVHVVHRRGELRASKIMQDRARKNPKIELVLNAVVDEILGDGKAVTGVRLKDTRDGSTRELPLKGVFMGIGHE
PNTGIFKGQLEMNEVGYLAVKAPSTATSVPGVFAAGDVSDPHYRQAISAAGTGCSAAIDAERWLGEHVTESWN

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=312, Percent_Identity=55.7692307692308, Blast_Score=352, Evalue=2e-98,
Organism=Escherichia coli, GI87081763, Length=304, Percent_Identity=33.8815789473684, Blast_Score=154, Evalue=7e-39,
Organism=Saccharomyces cerevisiae, GI6320560, Length=313, Percent_Identity=51.7571884984025, Blast_Score=338, Evalue=5e-94,
Organism=Saccharomyces cerevisiae, GI6321898, Length=313, Percent_Identity=51.1182108626198, Blast_Score=332, Evalue=6e-92,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33923; Mature: 33792

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKHERLVIVGSGPAGYTAALYAARANLQPLLFEGMQPGGQLTITSEVENFPGFPEGILG
CCCCCEEEEEECCCCCHHHHHHHHHCCCCHHHHHCCCCCCCEEEEECHHCCCCCCCCCCC
PELMEKMKKQAERFGTRFEASEITRVDFSQRPFKLWQDDTLYTADAVIVATGASAKWLQI
HHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCEECCCCCEEECCEEEEEECCCCEEEEC
PSEKQYQGRGVSACATCDGFFFRGVEIAVVGGGDTALEEASFLTKYASKVHVVHRRGELR
CCCCCCCCCCCEEEEECCCCEECCEEEEEECCCCHHHHHHHHHHHHHHHEEEEHHCCCHH
ASKIMQDRARKNPKIELVLNAVVDEILGDGKAVTGVRLKDTRDGSTRELPLKGVFMGIGH
HHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCEEEEEECCC
EPNTGIFKGQLEMNEVGYLAVKAPSTATSVPGVFAAGDVSDPHYRQAISAAGTGCSAAID
CCCCCEEEEEEEECCCEEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHCCCCCCCEEC
AERWLGEHVTESWN
HHHHHHHHHHCCCC
>Mature Secondary Structure 
SKHERLVIVGSGPAGYTAALYAARANLQPLLFEGMQPGGQLTITSEVENFPGFPEGILG
CCCCEEEEEECCCCCHHHHHHHHHCCCCHHHHHCCCCCCCEEEEECHHCCCCCCCCCCC
PELMEKMKKQAERFGTRFEASEITRVDFSQRPFKLWQDDTLYTADAVIVATGASAKWLQI
HHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCEECCCCCEEECCEEEEEECCCCEEEEC
PSEKQYQGRGVSACATCDGFFFRGVEIAVVGGGDTALEEASFLTKYASKVHVVHRRGELR
CCCCCCCCCCCEEEEECCCCEECCEEEEEECCCCHHHHHHHHHHHHHHHEEEEHHCCCHH
ASKIMQDRARKNPKIELVLNAVVDEILGDGKAVTGVRLKDTRDGSTRELPLKGVFMGIGH
HHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCEEEEEECCC
EPNTGIFKGQLEMNEVGYLAVKAPSTATSVPGVFAAGDVSDPHYRQAISAAGTGCSAAID
CCCCCEEEEEEEECCCEEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHCCCCCCCEEC
AERWLGEHVTESWN
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]