Click here to switch to the map view.

The map label for this gene is algU [H]

Identifier: 220918961

GI number: 220918961

Start: 4313700

End: 4314392

Strand: Direct

Name: algU [H]

Synonym: A2cp1_3876

Alternate gene names: 220918961

Gene position: 4313700-4314392 (Clockwise)

Preceding gene: 220918960

Following gene: 220918962

Centisome position: 85.77

GC content: 74.6

Gene sequence:

>693_bases
ATGGCGGCCGCGCTAGTGTTCGCTCGAAGCGTCGTTCGATGGTCGAAGGGGGATCCCATCGCTCGCCTGGCCCAGAGACT
CGCGCTCGCCGCTCCCGTGACGCCGCAGGCCGAGGCGGACGTCCTCGACCTCGCCGAGCTCGCGGATCGCGACGCGGTCG
AGCGCACCCTCGCCGGCGACACCGACGCGTTCGCGGGCGTGGTCCGCCGCCACGCCGGCGGCCTGGTCGGCATGTGCAGC
CGCATGGTGAGCGACCCGCGCCTGGGCGAGGAGCTCGCGCAGGAGGCGTTCGCGCGCGCCTACACGCGGCTCGCCTCGTT
CCGCGGCGACTGCCGCTTCCGCCACTGGCTCTACCGCATCGCCGTGAACGGCTGCCGCGACTGGCTGAAGGCCGGGGCGC
GGGCGGAGCGCGCCAGCGACCTCTCCGGCGACGAGCTGGTCAGCGCGGTGGACCCGGAGCGCGACGCCGCCGCCCGGCAG
GCGCTGCTCGCGCTGCAGGGCGCGCTCGCCGCGCTCCCGGCCAAGTACCGCGAGGCGTTCACGCTGTTCCACGTCGAGAA
CCTTCCCTACGAGGAGATCGAGGCGGCCACCGGCGTGCGCGTCAACGCGCTGAAGGTGCGCGTGCACCGCGCGCGCCTGA
TGCTGCGCGAGCGCCTCGGCGACCTGCTCGATCCCGACGAGGTGACGCCGTGA

Upstream 100 bases:

>100_bases
GCCCTCGACGTGGGGAGGCGAGAAGGTCGGAGCACCCACCATCCCTGACCGGCTCGCACCCGATAGCGTCGCGTCGCGCG
TTCACGGCCCTTTCCGCCCC

Downstream 100 bases:

>100_bases
CGGAGCGCGAGCTCCAGGACCTGCTGGACGGCCGCCCCGGTCCGCTCGCCGCGGAGCGGCTGCTGTCGTCCCTGCCGCCG
GAGGAGCGCCAGGCCGCGCT

Product: ECF subfamily RNA polymerase sigma-24 subunit

Products: NA

Alternate protein names: Sigma-30 [H]

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MAAALVFARSVVRWSKGDPIARLAQRLALAAPVTPQAEADVLDLAELADRDAVERTLAGDTDAFAGVVRRHAGGLVGMCS
RMVSDPRLGEELAQEAFARAYTRLASFRGDCRFRHWLYRIAVNGCRDWLKAGARAERASDLSGDELVSAVDPERDAAARQ
ALLALQGALAALPAKYREAFTLFHVENLPYEEIEAATGVRVNALKVRVHRARLMLRERLGDLLDPDEVTP

Sequences:

>Translated_230_residues
MAAALVFARSVVRWSKGDPIARLAQRLALAAPVTPQAEADVLDLAELADRDAVERTLAGDTDAFAGVVRRHAGGLVGMCS
RMVSDPRLGEELAQEAFARAYTRLASFRGDCRFRHWLYRIAVNGCRDWLKAGARAERASDLSGDELVSAVDPERDAAARQ
ALLALQGALAALPAKYREAFTLFHVENLPYEEIEAATGVRVNALKVRVHRARLMLRERLGDLLDPDEVTP
>Mature_229_residues
AAALVFARSVVRWSKGDPIARLAQRLALAAPVTPQAEADVLDLAELADRDAVERTLAGDTDAFAGVVRRHAGGLVGMCSR
MVSDPRLGEELAQEAFARAYTRLASFRGDCRFRHWLYRIAVNGCRDWLKAGARAERASDLSGDELVSAVDPERDAAARQA
LLALQGALAALPAKYREAFTLFHVENLPYEEIEAATGVRVNALKVRVHRARLMLRERLGDLLDPDEVTP

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor regulates genes such as algD, involved in alginate biosynthesis [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=187, Percent_Identity=33.6898395721925, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR014286
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 25172; Mature: 25041

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAALVFARSVVRWSKGDPIARLAQRLALAAPVTPQAEADVLDLAELADRDAVERTLAGD
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
TDAFAGVVRRHAGGLVGMCSRMVSDPRLGEELAQEAFARAYTRLASFRGDCRFRHWLYRI
HHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AVNGCRDWLKAGARAERASDLSGDELVSAVDPERDAAARQALLALQGALAALPAKYREAF
HHHHHHHHHHCCCHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLFHVENLPYEEIEAATGVRVNALKVRVHRARLMLRERLGDLLDPDEVTP
HHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
AAALVFARSVVRWSKGDPIARLAQRLALAAPVTPQAEADVLDLAELADRDAVERTLAGD
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
TDAFAGVVRRHAGGLVGMCSRMVSDPRLGEELAQEAFARAYTRLASFRGDCRFRHWLYRI
HHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AVNGCRDWLKAGARAERASDLSGDELVSAVDPERDAAARQALLALQGALAALPAKYREAF
HHHHHHHHHHCCCHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLFHVENLPYEEIEAATGVRVNALKVRVHRARLMLRERLGDLLDPDEVTP
HHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8432708; 8378309; 7961421; 10984043; 7737518 [H]