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The map label for this gene is 220918628

Identifier: 220918628

GI number: 220918628

Start: 3951748

End: 3953532

Strand: Direct

Name: 220918628

Synonym: A2cp1_3536

Alternate gene names: NA

Gene position: 3951748-3953532 (Clockwise)

Preceding gene: 220918627

Following gene: 220918630

Centisome position: 78.57

GC content: 75.85

Gene sequence:

>1785_bases
ATGCGCCCGCGCGCACTCCTCTACCGGCTCCGCTCCTGGTTCTACCGCCGGGACGTGACGCTCTGGTACGACCCGCGCTA
CCGCCTGCCGCTCTCCGGCCTCGAGTCCGGCGCCGGCATGGAGCCGCGCCGCGCCGACTTCGTGGCCTGGTGGCTCGCCG
ACTCCGGCGCCGTGCCGCGCTCCCGGCGCCGCACGCCGCGGCGGATCTCGTTCGAGGACCTGGCGCGCGTGCACGACGCG
GAGCTGCTCGAGTCGCTGGGCCACCCCGACACGCTGGCGCGGGTGTTCGCGGTGGACCCGTCCGACGTCCCGGTGGACGA
GGTCATGACCACCGTCCGGCTGGCCTGCGGCGGCACCCTGGGCGCGGCCCGCGAGACGCTCCGCACGCGCGCCCCCGCCA
TCAACCTCCTGGGCGGCTTCCACCACGCGTTCCCCGGCGCCGCGGGCGGCTTCTGCCCGGTCAACGACGTCGCCGTCGCG
ATCGCCGCGGTGCGCGCGGAGGGGTTCTCGGGGCGCGTGGCGGTCCTCGATCTCGACGCGCACCCGCCCGACGGCATCGC
CGCCTGCCTGGCGCAGGATCCCGATCACTGGATCGGCTCCATCTCCGGGTCGGACTGGGGGCCGCTCGAGGGCGTGGACG
AGACGGTGCTCCCGCCGGGCAGCGGCGACGACCCCTACCTCGAGGCGCTCGGCGCGCTGCTCTCGCGGATGCCGCGGCCG
CAGCTCGCGTTCGTGCTGGCCGGGGGCGACGTGCTGGCCGGCGATCGCTTCGGCCAGCTCGGGCTGTCGCTCGACGGCGC
GCGCGAGCGCGACCTGCTCGTCGCCGCCGAGCTGGACTTCGTGCCCACCGTGTGGCTCTCGGCGGGCGGCTACTCGCGGC
GATCCTGGCGCGCGCTGGCCGGCACGGGCATGGCGGTCGCGGCCGGCTCGCTCGCGCCCATCCCCGACGAGTACGACCCG
CTCTCCGCCCGCTTCGAGATGGTCTCGCAGAAGCTCCTGCCCGGCGATCTCGGCGACACCGGCGACATCACCGCCGAGGA
TCTCGAGGAGGCGCTCGGCATGCGGCCGCGGCGCCAGCGGCTGCTGCTCGGCTTCTACACCGCCTCCGGCATCGAGCACG
CGCTGTTCCGCTACGGCGTGCTGGAGCAGCTCGAGCGCATGGGCTACCGGCAGTTCCGGGTCGGGTTCGACTCCGCCGGG
CTGGGCGATCGGGTGCGGCTCCACGGCGAGGCGGAGGGGCAGGAGCACCTGCTCGTCGAGCTGATCCTGGAACGGCGACA
CGTGCTCGGGGTCGAGGTGCTGTTCGTGCACTGGCTCTCGCTGCGCAACCCGCGGGCGCAGTTCAGCGACCGCCGCCCGC
GCCTCCCGGGGCAGGAGGTGCCGGGGCTCGGCCTGGCGCACGAGGCCGGGTCGATGCTGGCGCGCATGGCCATCCGCCTC
GGGCTGGGCGGCGTCGCGTTCCGGCCGGCGCACTTCCACACCGCCTACGCCGCCCGCCACGCGTTCGCGTTCATCGACCC
GGAGCGGCAGGGGCGCTTCGAGGCGCTGGTGCGGGACCTCGCGACGGTGCCGCTCCTCGAGGCGACGCGCGCGGTCTCCG
AAGGCCGGGTGCTCCTCGACGGGCGCCCCTACGCGTGGGAGGCGGACGAGATGGCGTACTGGCTGCGCGAGTCGCCGTCC
GAGCCGGGGGAGGCGGAGCGCGAGCGCGAGCGGGTCCGCTTCACGCTGCTGCCGGAGGCGCCCCCGCCGGCGGTCAGGGC
GCCGGCTCCGCCAGGAGCAGCCTGA

Upstream 100 bases:

>100_bases
TGGTCCGGCCGCCGGAAGGGCGCCGCCCGCGTGCCCCCGCCGGCGAGCGGCGAGCCGCCGTTCGCGCCGCCGCCGCGCGG
GTGAGCCCGGGCGCCGCGTG

Downstream 100 bases:

>100_bases
CCTCCTCCTCCAGCTTCTCTCCCTCGGCGCGGTCGTAGCCACGGTGGACGTGGCGCACCAGCCCGCGACGGTCGATCACG
AGCGTCGTGGGCAGCCGCTG

Product: histone deacetylase superfamily

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 594; Mature: 594

Protein sequence:

>594_residues
MRPRALLYRLRSWFYRRDVTLWYDPRYRLPLSGLESGAGMEPRRADFVAWWLADSGAVPRSRRRTPRRISFEDLARVHDA
ELLESLGHPDTLARVFAVDPSDVPVDEVMTTVRLACGGTLGAARETLRTRAPAINLLGGFHHAFPGAAGGFCPVNDVAVA
IAAVRAEGFSGRVAVLDLDAHPPDGIAACLAQDPDHWIGSISGSDWGPLEGVDETVLPPGSGDDPYLEALGALLSRMPRP
QLAFVLAGGDVLAGDRFGQLGLSLDGARERDLLVAAELDFVPTVWLSAGGYSRRSWRALAGTGMAVAAGSLAPIPDEYDP
LSARFEMVSQKLLPGDLGDTGDITAEDLEEALGMRPRRQRLLLGFYTASGIEHALFRYGVLEQLERMGYRQFRVGFDSAG
LGDRVRLHGEAEGQEHLLVELILERRHVLGVEVLFVHWLSLRNPRAQFSDRRPRLPGQEVPGLGLAHEAGSMLARMAIRL
GLGGVAFRPAHFHTAYAARHAFAFIDPERQGRFEALVRDLATVPLLEATRAVSEGRVLLDGRPYAWEADEMAYWLRESPS
EPGEAERERERVRFTLLPEAPPPAVRAPAPPGAA

Sequences:

>Translated_594_residues
MRPRALLYRLRSWFYRRDVTLWYDPRYRLPLSGLESGAGMEPRRADFVAWWLADSGAVPRSRRRTPRRISFEDLARVHDA
ELLESLGHPDTLARVFAVDPSDVPVDEVMTTVRLACGGTLGAARETLRTRAPAINLLGGFHHAFPGAAGGFCPVNDVAVA
IAAVRAEGFSGRVAVLDLDAHPPDGIAACLAQDPDHWIGSISGSDWGPLEGVDETVLPPGSGDDPYLEALGALLSRMPRP
QLAFVLAGGDVLAGDRFGQLGLSLDGARERDLLVAAELDFVPTVWLSAGGYSRRSWRALAGTGMAVAAGSLAPIPDEYDP
LSARFEMVSQKLLPGDLGDTGDITAEDLEEALGMRPRRQRLLLGFYTASGIEHALFRYGVLEQLERMGYRQFRVGFDSAG
LGDRVRLHGEAEGQEHLLVELILERRHVLGVEVLFVHWLSLRNPRAQFSDRRPRLPGQEVPGLGLAHEAGSMLARMAIRL
GLGGVAFRPAHFHTAYAARHAFAFIDPERQGRFEALVRDLATVPLLEATRAVSEGRVLLDGRPYAWEADEMAYWLRESPS
EPGEAERERERVRFTLLPEAPPPAVRAPAPPGAA
>Mature_594_residues
MRPRALLYRLRSWFYRRDVTLWYDPRYRLPLSGLESGAGMEPRRADFVAWWLADSGAVPRSRRRTPRRISFEDLARVHDA
ELLESLGHPDTLARVFAVDPSDVPVDEVMTTVRLACGGTLGAARETLRTRAPAINLLGGFHHAFPGAAGGFCPVNDVAVA
IAAVRAEGFSGRVAVLDLDAHPPDGIAACLAQDPDHWIGSISGSDWGPLEGVDETVLPPGSGDDPYLEALGALLSRMPRP
QLAFVLAGGDVLAGDRFGQLGLSLDGARERDLLVAAELDFVPTVWLSAGGYSRRSWRALAGTGMAVAAGSLAPIPDEYDP
LSARFEMVSQKLLPGDLGDTGDITAEDLEEALGMRPRRQRLLLGFYTASGIEHALFRYGVLEQLERMGYRQFRVGFDSAG
LGDRVRLHGEAEGQEHLLVELILERRHVLGVEVLFVHWLSLRNPRAQFSDRRPRLPGQEVPGLGLAHEAGSMLARMAIRL
GLGGVAFRPAHFHTAYAARHAFAFIDPERQGRFEALVRDLATVPLLEATRAVSEGRVLLDGRPYAWEADEMAYWLRESPS
EPGEAERERERVRFTLLPEAPPPAVRAPAPPGAA

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI217272877, Length=298, Percent_Identity=29.5302013422819, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI13128860, Length=379, Percent_Identity=24.5382585751979, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI209862883, Length=209, Percent_Identity=32.0574162679426, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI293336691, Length=278, Percent_Identity=25.8992805755396, Blast_Score=79, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI193207430, Length=335, Percent_Identity=26.2686567164179, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17508561, Length=336, Percent_Identity=27.3809523809524, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17561978, Length=307, Percent_Identity=27.6872964169381, Blast_Score=84, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323999, Length=309, Percent_Identity=24.5954692556634, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24657891, Length=370, Percent_Identity=23.5135135135135, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24649807, Length=248, Percent_Identity=30.241935483871, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 64981; Mature: 64981

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPRALLYRLRSWFYRRDVTLWYDPRYRLPLSGLESGAGMEPRRADFVAWWLADSGAVPR
CCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCH
SRRRTPRRISFEDLARVHDAELLESLGHPDTLARVFAVDPSDVPVDEVMTTVRLACGGTL
HHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHEEEEEECCCCCCHHHHHHHHHHHCCCCH
GAARETLRTRAPAINLLGGFHHAFPGAAGGFCPVNDVAVAIAAVRAEGFSGRVAVLDLDA
HHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECC
HPPDGIAACLAQDPDHWIGSISGSDWGPLEGVDETVLPPGSGDDPYLEALGALLSRMPRP
CCCCHHHHHHHCCCCHHEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
QLAFVLAGGDVLAGDRFGQLGLSLDGARERDLLVAAELDFVPTVWLSAGGYSRRSWRALA
CEEEEEECCCEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCHHHHH
GTGMAVAAGSLAPIPDEYDPLSARFEMVSQKLLPGDLGDTGDITAEDLEEALGMRPRRQR
CCCHHEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCHHE
LLLGFYTASGIEHALFRYGVLEQLERMGYRQFRVGFDSAGLGDRVRLHGEAEGQEHLLVE
EEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCEEEEECCCCCHHHHHHH
LILERRHVLGVEVLFVHWLSLRNPRAQFSDRRPRLPGQEVPGLGLAHEAGSMLARMAIRL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
GLGGVAFRPAHFHTAYAARHAFAFIDPERQGRFEALVRDLATVPLLEATRAVSEGRVLLD
CCCCEEECCCHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHCHHHHHHHHHHCCEEEEC
GRPYAWEADEMAYWLRESPSEPGEAERERERVRFTLLPEAPPPAVRAPAPPGAA
CCCCCCCHHHHHHHHHCCCCCCCHHHHHHHCEEEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRPRALLYRLRSWFYRRDVTLWYDPRYRLPLSGLESGAGMEPRRADFVAWWLADSGAVPR
CCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCH
SRRRTPRRISFEDLARVHDAELLESLGHPDTLARVFAVDPSDVPVDEVMTTVRLACGGTL
HHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHEEEEEECCCCCCHHHHHHHHHHHCCCCH
GAARETLRTRAPAINLLGGFHHAFPGAAGGFCPVNDVAVAIAAVRAEGFSGRVAVLDLDA
HHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECC
HPPDGIAACLAQDPDHWIGSISGSDWGPLEGVDETVLPPGSGDDPYLEALGALLSRMPRP
CCCCHHHHHHHCCCCHHEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
QLAFVLAGGDVLAGDRFGQLGLSLDGARERDLLVAAELDFVPTVWLSAGGYSRRSWRALA
CEEEEEECCCEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCHHHHH
GTGMAVAAGSLAPIPDEYDPLSARFEMVSQKLLPGDLGDTGDITAEDLEEALGMRPRRQR
CCCHHEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCHHE
LLLGFYTASGIEHALFRYGVLEQLERMGYRQFRVGFDSAGLGDRVRLHGEAEGQEHLLVE
EEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCEEEEECCCCCHHHHHHH
LILERRHVLGVEVLFVHWLSLRNPRAQFSDRRPRLPGQEVPGLGLAHEAGSMLARMAIRL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
GLGGVAFRPAHFHTAYAARHAFAFIDPERQGRFEALVRDLATVPLLEATRAVSEGRVLLD
CCCCEEECCCHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHCHHHHHHHHHHCCEEEEC
GRPYAWEADEMAYWLRESPSEPGEAERERERVRFTLLPEAPPPAVRAPAPPGAA
CCCCCCCHHHHHHHHHCCCCCCCHHHHHHHCEEEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7678591 [H]