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The map label for this gene is cotH [H]

Identifier: 220918553

GI number: 220918553

Start: 3864674

End: 3866347

Strand: Direct

Name: cotH [H]

Synonym: A2cp1_3461

Alternate gene names: 220918553

Gene position: 3864674-3866347 (Clockwise)

Preceding gene: 220918552

Following gene: 220918562

Centisome position: 76.84

GC content: 73.3

Gene sequence:

>1674_bases
ATGCGACGCACCTCGGCGGCCGCCGTTCTCCTGCTTCCGTTCCTCCTGCTCGCCTGCAACGGCGCGCCCCTCCCCGACGC
CTCGCTGGGCGGCCAGCCGGGCGGTGGTGGACCGGGCGGCCAGCCGGGCGGAGGAGGTGGCGGCGGCGGCGCCGGGTCGG
TGAACCCCGACGCCCCGCTCGCCGCGCCCGCCTGGCCTCCGCTGCAGGCCAGCGTCGAGCCGTACGCGCTCGCGTTCGAC
GACGCGACGGCGGCCATCGTCTACACGATGTGGAGCAAGGACTACGCGCCGGGCCGGTTCCACTACCACGGCGCCTGGTG
GGACGTTGAGCTGCGCCAGCGCGGCGACGGCTCGCGCGAGCACCCCAAGCACAGCTGGAAGGTGCGCCGCCCGAAGGACG
CGCCGCTCGACGGCGAGCGCACGCGCAACCTGCTCGCGGAGTGGCCCGACGGCGGCTACCTGTCGGACCCGTTCTCCTAC
GGGCTCATGAAGGGCGCCGGCGTGCCCACGCCGCGGGCGCAGTTCGTGACGCTCGACGTCAACGGCGAGCACCAGGGCGT
GTACGTCGAGCTCGAGGAGCCGGACGAGAAGCACTTCCTCCTGGAGAACGGCATCGACTCGAACGCCAACGTCTACCGCT
GCGGGCTGCGCGACTGCGAGCTGAAGCTCACCCCGCCCGCCCACTACCAGGGGCCGTGGGAGAAGAAGACGAACGAGAGC
GAGCCCTCCGACGACCTCGACGCGTTCCTGATCGGCCTGAACCGCACGCCCGAGGGCGAGATCGAGGCGTGGCTGGAGCA
GCACGTCGACCTGCCGCGCTTCTTCCGCTTCTACGCGGTGGGCATCCTCATCAGCCTCTCCGGCATCGACGACTCCGGCA
GCTACCTCGTGCACGACCGCACGCGCGACAAGTGGCTGTGGGTGCCGTGGGATCTCAACAACGCGAAGCTGGTGTTCTGG
CGCGACAACCCGGTGGAGTGGGGCGTGCCGTTCCGCTACGCGATCCCGTTCTACACGCTCTACGACGCCGCCACCCTGGG
CGTCGCGGCCGGCAAGGAGGCGCGCTACGGCGGCGCGCACCCGCCGTTCGTGGTGCTGTTCCAGCGCATCTGGGACCGGC
CGGCGCTGCGCGACCGCATCCTCGACGAGGTGGAGGCGATGCTCGACGGCCCGTTCGCCGAGTCCGAGACGTCGCCGCGC
ATCGACGGGCTGCGCGCGCTCATCGCCGGGCTGCTCCCGGCCGATCCCTGGGTGGAGCCGGCGCACGCGGACGCCTCGGT
GCAGGTGCTGAAGGACTACGTCCGGCGGCGGACCGGGTTCCTGCGCGAGCAGATCGCGCTCGAGCGACACCGCGGCGAGG
GAGGCCTGGTGGTGAACGCGATCGCGCCGGACGCGATCGAGCTCTACAACCGCGAGGACGCGCCGCGCGACCTGGGCGGC
CTGGCCCTGACCGGCGACCTGCGCCAGCGGCTCGCGACGCTGCTGCCCGCCGGCACGGTGGTGCCGCCGCACGGCACGCT
GCGGCTCCCGTTCCCGGTGGCGGCCGAGGGCGGCGAGGTCGGGATCTTCGACGTCGCGACCCAGCTGCCGGTGGACGCCG
TCTACTACGGGCCGCCCGGCGGGCGGACCTACGCGCGCACGCCGGACGGCGCGGAGACCTGGGCCTGGCGGTGA

Upstream 100 bases:

>100_bases
CCAGGCAGCTCCGCCCCGCCGGGCGGGGCGCCGCCCCGTAGAAGGGGAAGCCCCCGCGTGCCCGCTTCCCCGCGCGCCGA
CCGCTGCGCTGCATGTGCTC

Downstream 100 bases:

>100_bases
GTGGGGGAGCCGGGGCGGGCGCGCGGCGAGGACCGCGCGCGCCCGCCGCCCGGATCAGAACGTGTAGCGGACCGTCGGGT
AGACCGCGTACCCGCTCGCC

Product: Spore coat protein CotH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 557; Mature: 557

Protein sequence:

>557_residues
MRRTSAAAVLLLPFLLLACNGAPLPDASLGGQPGGGGPGGQPGGGGGGGGAGSVNPDAPLAAPAWPPLQASVEPYALAFD
DATAAIVYTMWSKDYAPGRFHYHGAWWDVELRQRGDGSREHPKHSWKVRRPKDAPLDGERTRNLLAEWPDGGYLSDPFSY
GLMKGAGVPTPRAQFVTLDVNGEHQGVYVELEEPDEKHFLLENGIDSNANVYRCGLRDCELKLTPPAHYQGPWEKKTNES
EPSDDLDAFLIGLNRTPEGEIEAWLEQHVDLPRFFRFYAVGILISLSGIDDSGSYLVHDRTRDKWLWVPWDLNNAKLVFW
RDNPVEWGVPFRYAIPFYTLYDAATLGVAAGKEARYGGAHPPFVVLFQRIWDRPALRDRILDEVEAMLDGPFAESETSPR
IDGLRALIAGLLPADPWVEPAHADASVQVLKDYVRRRTGFLREQIALERHRGEGGLVVNAIAPDAIELYNREDAPRDLGG
LALTGDLRQRLATLLPAGTVVPPHGTLRLPFPVAAEGGEVGIFDVATQLPVDAVYYGPPGGRTYARTPDGAETWAWR

Sequences:

>Translated_557_residues
MRRTSAAAVLLLPFLLLACNGAPLPDASLGGQPGGGGPGGQPGGGGGGGGAGSVNPDAPLAAPAWPPLQASVEPYALAFD
DATAAIVYTMWSKDYAPGRFHYHGAWWDVELRQRGDGSREHPKHSWKVRRPKDAPLDGERTRNLLAEWPDGGYLSDPFSY
GLMKGAGVPTPRAQFVTLDVNGEHQGVYVELEEPDEKHFLLENGIDSNANVYRCGLRDCELKLTPPAHYQGPWEKKTNES
EPSDDLDAFLIGLNRTPEGEIEAWLEQHVDLPRFFRFYAVGILISLSGIDDSGSYLVHDRTRDKWLWVPWDLNNAKLVFW
RDNPVEWGVPFRYAIPFYTLYDAATLGVAAGKEARYGGAHPPFVVLFQRIWDRPALRDRILDEVEAMLDGPFAESETSPR
IDGLRALIAGLLPADPWVEPAHADASVQVLKDYVRRRTGFLREQIALERHRGEGGLVVNAIAPDAIELYNREDAPRDLGG
LALTGDLRQRLATLLPAGTVVPPHGTLRLPFPVAAEGGEVGIFDVATQLPVDAVYYGPPGGRTYARTPDGAETWAWR
>Mature_557_residues
MRRTSAAAVLLLPFLLLACNGAPLPDASLGGQPGGGGPGGQPGGGGGGGGAGSVNPDAPLAAPAWPPLQASVEPYALAFD
DATAAIVYTMWSKDYAPGRFHYHGAWWDVELRQRGDGSREHPKHSWKVRRPKDAPLDGERTRNLLAEWPDGGYLSDPFSY
GLMKGAGVPTPRAQFVTLDVNGEHQGVYVELEEPDEKHFLLENGIDSNANVYRCGLRDCELKLTPPAHYQGPWEKKTNES
EPSDDLDAFLIGLNRTPEGEIEAWLEQHVDLPRFFRFYAVGILISLSGIDDSGSYLVHDRTRDKWLWVPWDLNNAKLVFW
RDNPVEWGVPFRYAIPFYTLYDAATLGVAAGKEARYGGAHPPFVVLFQRIWDRPALRDRILDEVEAMLDGPFAESETSPR
IDGLRALIAGLLPADPWVEPAHADASVQVLKDYVRRRTGFLREQIALERHRGEGGLVVNAIAPDAIELYNREDAPRDLGG
LALTGDLRQRLATLLPAGTVVPPHGTLRLPFPVAAEGGEVGIFDVATQLPVDAVYYGPPGGRTYARTPDGAETWAWR

Specific function: Involved in the assembly of several proteins in the inner and outer layer of the spore coat. Stabilizes CotC and CotU in the mother cell compartment of sporulating cells and promotes the assembly of both early and late forms of CotC-related polypeptides o

COG id: COG5337

COG function: function code M; Spore coat assembly protein

Gene ontology:

Cell location: Spore wall, spore coat [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CotH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014867 [H]

Pfam domain/function: PF08757 CotH [H]

EC number: NA

Molecular weight: Translated: 61008; Mature: 61008

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRTSAAAVLLLPFLLLACNGAPLPDASLGGQPGGGGPGGQPGGGGGGGGAGSVNPDAPL
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AAPAWPPLQASVEPYALAFDDATAAIVYTMWSKDYAPGRFHYHGAWWDVELRQRGDGSRE
CCCCCCCCCCCCCCEEEEECCCCEEEEEEEECCCCCCCEEEEECEEEEEEHHHCCCCCCC
HPKHSWKVRRPKDAPLDGERTRNLLAEWPDGGYLSDPFSYGLMKGAGVPTPRAQFVTLDV
CCCCCCEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCEEEEEEE
NGEHQGVYVELEEPDEKHFLLENGIDSNANVYRCGLRDCELKLTPPAHYQGPWEKKTNES
CCCCCCEEEEECCCCCCEEEEECCCCCCCCEEEECCCCCEEEECCCCCCCCCCCCCCCCC
EPSDDLDAFLIGLNRTPEGEIEAWLEQHVDLPRFFRFYAVGILISLSGIDDSGSYLVHDR
CCCCCCEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHEEEEECCCCCCCEEEEEC
TRDKWLWVPWDLNNAKLVFWRDNPVEWGVPFRYAIPFYTLYDAATLGVAAGKEARYGGAH
CCCCEEEEEEECCCCEEEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCCC
PPFVVLFQRIWDRPALRDRILDEVEAMLDGPFAESETSPRIDGLRALIAGLLPADPWVEP
CHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
AHADASVQVLKDYVRRRTGFLREQIALERHRGEGGLVVNAIAPDAIELYNREDAPRDLGG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHCCCCCCCCCCC
LALTGDLRQRLATLLPAGTVVPPHGTLRLPFPVAAEGGEVGIFDVATQLPVDAVYYGPPG
EEEEHHHHHHHHHHCCCCCEECCCCCEECCCCEECCCCCEEEEEHHHHCCCCEEEECCCC
GRTYARTPDGAETWAWR
CCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRRTSAAAVLLLPFLLLACNGAPLPDASLGGQPGGGGPGGQPGGGGGGGGAGSVNPDAPL
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AAPAWPPLQASVEPYALAFDDATAAIVYTMWSKDYAPGRFHYHGAWWDVELRQRGDGSRE
CCCCCCCCCCCCCCEEEEECCCCEEEEEEEECCCCCCCEEEEECEEEEEEHHHCCCCCCC
HPKHSWKVRRPKDAPLDGERTRNLLAEWPDGGYLSDPFSYGLMKGAGVPTPRAQFVTLDV
CCCCCCEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCEEEEEEE
NGEHQGVYVELEEPDEKHFLLENGIDSNANVYRCGLRDCELKLTPPAHYQGPWEKKTNES
CCCCCCEEEEECCCCCCEEEEECCCCCCCCEEEECCCCCEEEECCCCCCCCCCCCCCCCC
EPSDDLDAFLIGLNRTPEGEIEAWLEQHVDLPRFFRFYAVGILISLSGIDDSGSYLVHDR
CCCCCCEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHEEEEECCCCCCCEEEEEC
TRDKWLWVPWDLNNAKLVFWRDNPVEWGVPFRYAIPFYTLYDAATLGVAAGKEARYGGAH
CCCCEEEEEEECCCCEEEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCCC
PPFVVLFQRIWDRPALRDRILDEVEAMLDGPFAESETSPRIDGLRALIAGLLPADPWVEP
CHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
AHADASVQVLKDYVRRRTGFLREQIALERHRGEGGLVVNAIAPDAIELYNREDAPRDLGG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHCCCCCCCCCCC
LALTGDLRQRLATLLPAGTVVPPHGTLRLPFPVAAEGGEVGIFDVATQLPVDAVYYGPPG
EEEEHHHHHHHHHHCCCCCEECCCCCEECCCCEECCCCCEEEEEHHHHCCCCEEEECCCC
GRTYARTPDGAETWAWR
CCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8755863; 8991897; 9353933; 9384377; 7814326; 10198031 [H]