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The map label for this gene is fprA [H]

Identifier: 220918530

GI number: 220918530

Start: 3825250

End: 3826590

Strand: Reverse

Name: fprA [H]

Synonym: A2cp1_3438

Alternate gene names: 220918530

Gene position: 3826590-3825250 (Counterclockwise)

Preceding gene: 220918531

Following gene: 220918526

Centisome position: 76.09

GC content: 75.32

Gene sequence:

>1341_bases
ATGCGCGTCGCGATCATCGGCTCCGGTCCTGCCGGCTTCTACGCGGCCGAGGCGCTGCTGAAGCGGACCGACGTGGCGGT
GGACGTGGACATGTTCGATCGCCTCCCCACGCCGTTCGGGCTGGTGCGAGGCGGGGTCGCGCCCGATCACCAGAAGATCA
AGGCGGTCACCCGCGTCTTCGCGAGCACGGCGGCACGGCCCACCTTCCGGTTCCTCGGCAACGTGCGGCTCGGGCAGGAC
GTCACGGTGGACGAGCTTCGCCGGCACTACCACCAGATCGTCTACGCCACCGGCAACGAGTCCGACCGGCGGCTCGGCAT
CCCGGGCGAGGGGATCGAGCGCTGCACGCCGGCGACGGTGTTCGTCGGCTGGTACAACGGCCACCCGGACTATCGCCACG
CGCGGTTCGACCTGTCGGTCCGGCGGGCCGCGGTGGTGGGCAACGGCAACGTCGCGGTCGACGTCGCCCGCATCCTGCTG
CGCACGCGGGCCGAGCTCGAGCGGACCGACATCGCGGCGCACGCGCTCGAGGCCCTGCGCGAGAGCCAGGTCCGCGAGGT
GTACCTGCTCGGGCGGAGGGGCCCTGCGCAGGCGGCGTTCTCGCCGGCCGAGCTCCGGGAGCTCGGCACCCTCGAGGCGG
CGGACCCGGTCGTCGACCCCGCCGACCTCGCGGGCCTGAGCGACCCCGCGCCGGGCGGGAACCTGGAGATCCTCCGCGCC
TTCGCCGCGCGGCGGCCGCGCCCGGACGCGAGGAAGCTCCACCTCCGCTTCCTCGTGTCGCCGACGGAGGTGCTCCCGGA
TGCGGCCGGCGCGGTCGCGGGGCTGAGGCTCGAGAGGAACCGCCTGGAGACGAGGGCCGACGGCAGCGTCGCCGCGCGCG
GCACCGGCGAGACCGAGGTGCTGGAGGTCGGGCTGGTGCTGCCGGCGGTCGGCTACGCCGCGGAGCGCATCGCGGGCGTC
CCCTTCGACGAGAAGGCGCGGGTCGTCGCCAACGAGGACGGGCGGGTGGTCGACCCGGTCCGCCGCACGGTGTTCCCCGG
CGAGTACGTGGTCGGCTGGGCGCGCAGCGGACCGCAGGGGCTCATCGGCGAGCACCGGCGCGCCTCGGCAAACGTGGTGG
CGCACATGTTCGCGGACGGCGCCGGGCTCGAGGCCCGCGCGCTGCCCCCGCGCCACGCCATCGACGAGCTGCTGCGCGCG
CGCGGCGTCCGGCCGGTGTCGTTCGTGGACTGGGCGCGGCTCGACGAGGTGGAGGTCGCGCGCGGAGCACGCCGCGGCGC
CCCGCGCGACAAGCTCGTCGACGTGGCGGCGATGCTCGCGATCCTGGGCGAGCGGGAGTGA

Upstream 100 bases:

>100_bases
GCTACCGGGCAATCCGCCGAGGCCCCGCGTCGCAGGGCCTTCTCCGCGGTGTCTCGTAAGATGCGTCACGGTATCCGCCG
GACAGTAAGGAGCACCTCGC

Downstream 100 bases:

>100_bases
CGCTCACTCGCGCTGGAAGGTGAACTGCTGTCCGCCGATGGAGGCCTCGACCATCGCTCCGCCGATCGGCTTGACGAAGA
CCGCGACGCCGTCGGTGTAC

Product: Ferredoxin--NADP(+) reductase

Products: NA

Alternate protein names: NFR [H]

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MRVAIIGSGPAGFYAAEALLKRTDVAVDVDMFDRLPTPFGLVRGGVAPDHQKIKAVTRVFASTAARPTFRFLGNVRLGQD
VTVDELRRHYHQIVYATGNESDRRLGIPGEGIERCTPATVFVGWYNGHPDYRHARFDLSVRRAAVVGNGNVAVDVARILL
RTRAELERTDIAAHALEALRESQVREVYLLGRRGPAQAAFSPAELRELGTLEAADPVVDPADLAGLSDPAPGGNLEILRA
FAARRPRPDARKLHLRFLVSPTEVLPDAAGAVAGLRLERNRLETRADGSVAARGTGETEVLEVGLVLPAVGYAAERIAGV
PFDEKARVVANEDGRVVDPVRRTVFPGEYVVGWARSGPQGLIGEHRRASANVVAHMFADGAGLEARALPPRHAIDELLRA
RGVRPVSFVDWARLDEVEVARGARRGAPRDKLVDVAAMLAILGERE

Sequences:

>Translated_446_residues
MRVAIIGSGPAGFYAAEALLKRTDVAVDVDMFDRLPTPFGLVRGGVAPDHQKIKAVTRVFASTAARPTFRFLGNVRLGQD
VTVDELRRHYHQIVYATGNESDRRLGIPGEGIERCTPATVFVGWYNGHPDYRHARFDLSVRRAAVVGNGNVAVDVARILL
RTRAELERTDIAAHALEALRESQVREVYLLGRRGPAQAAFSPAELRELGTLEAADPVVDPADLAGLSDPAPGGNLEILRA
FAARRPRPDARKLHLRFLVSPTEVLPDAAGAVAGLRLERNRLETRADGSVAARGTGETEVLEVGLVLPAVGYAAERIAGV
PFDEKARVVANEDGRVVDPVRRTVFPGEYVVGWARSGPQGLIGEHRRASANVVAHMFADGAGLEARALPPRHAIDELLRA
RGVRPVSFVDWARLDEVEVARGARRGAPRDKLVDVAAMLAILGERE
>Mature_446_residues
MRVAIIGSGPAGFYAAEALLKRTDVAVDVDMFDRLPTPFGLVRGGVAPDHQKIKAVTRVFASTAARPTFRFLGNVRLGQD
VTVDELRRHYHQIVYATGNESDRRLGIPGEGIERCTPATVFVGWYNGHPDYRHARFDLSVRRAAVVGNGNVAVDVARILL
RTRAELERTDIAAHALEALRESQVREVYLLGRRGPAQAAFSPAELRELGTLEAADPVVDPADLAGLSDPAPGGNLEILRA
FAARRPRPDARKLHLRFLVSPTEVLPDAAGAVAGLRLERNRLETRADGSVAARGTGETEVLEVGLVLPAVGYAAERIAGV
PFDEKARVVANEDGRVVDPVRRTVFPGEYVVGWARSGPQGLIGEHRRASANVVAHMFADGAGLEARALPPRHAIDELLRA
RGVRPVSFVDWARLDEVEVARGARRGAPRDKLVDVAAMLAILGERE

Specific function: May serve as electron transfer protein and supply electrons to P450 systems [H]

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ferredoxin--NADP reductase type 1 family [H]

Homologues:

Organism=Homo sapiens, GI111118981, Length=464, Percent_Identity=45.6896551724138, Blast_Score=335, Evalue=4e-92,
Organism=Homo sapiens, GI111118983, Length=470, Percent_Identity=45.1063829787234, Blast_Score=329, Evalue=3e-90,
Organism=Caenorhabditis elegans, GI17543860, Length=452, Percent_Identity=32.0796460176991, Blast_Score=222, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6320584, Length=478, Percent_Identity=31.7991631799163, Blast_Score=224, Evalue=2e-59,
Organism=Drosophila melanogaster, GI17137178, Length=455, Percent_Identity=37.5824175824176, Blast_Score=267, Evalue=1e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR021163
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07992 Pyr_redox_2 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 48280; Mature: 48280

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVAIIGSGPAGFYAAEALLKRTDVAVDVDMFDRLPTPFGLVRGGVAPDHQKIKAVTRVF
CEEEEEECCCCHHHHHHHHHHHCCCEEEHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHH
ASTAARPTFRFLGNVRLGQDVTVDELRRHYHQIVYATGNESDRRLGIPGEGIERCTPATV
HHHCCCCHHHHHCCCCCCCCCCHHHHHHHHHEEEEEECCCCCCEECCCCCCHHHCCCCEE
FVGWYNGHPDYRHARFDLSVRRAAVVGNGNVAVDVARILLRTRAELERTDIAAHALEALR
EEEEECCCCCCCEEEECEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESQVREVYLLGRRGPAQAAFSPAELRELGTLEAADPVVDPADLAGLSDPAPGGNLEILRA
HHHHHEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHH
FAARRPRPDARKLHLRFLVSPTEVLPDAAGAVAGLRLERNRLETRADGSVAARGTGETEV
HHHCCCCCCHHEEEEEEEECHHHHCCCHHHHHHHHEEHHHHHHHCCCCCEEECCCCCHHH
LEVGLVLPAVGYAAERIAGVPFDEKARVVANEDGRVVDPVRRTVFPGEYVVGWARSGPQG
EEHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEECHHHHHCCCCCEEEEECCCCCCC
LIGEHRRASANVVAHMFADGAGLEARALPPRHAIDELLRARGVRPVSFVDWARLDEVEVA
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEEHHHHHHCCHHHHH
RGARRGAPRDKLVDVAAMLAILGERE
HHHHCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRVAIIGSGPAGFYAAEALLKRTDVAVDVDMFDRLPTPFGLVRGGVAPDHQKIKAVTRVF
CEEEEEECCCCHHHHHHHHHHHCCCEEEHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHH
ASTAARPTFRFLGNVRLGQDVTVDELRRHYHQIVYATGNESDRRLGIPGEGIERCTPATV
HHHCCCCHHHHHCCCCCCCCCCHHHHHHHHHEEEEEECCCCCCEECCCCCCHHHCCCCEE
FVGWYNGHPDYRHARFDLSVRRAAVVGNGNVAVDVARILLRTRAELERTDIAAHALEALR
EEEEECCCCCCCEEEECEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESQVREVYLLGRRGPAQAAFSPAELRELGTLEAADPVVDPADLAGLSDPAPGGNLEILRA
HHHHHEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHH
FAARRPRPDARKLHLRFLVSPTEVLPDAAGAVAGLRLERNRLETRADGSVAARGTGETEV
HHHCCCCCCHHEEEEEEEECHHHHCCCHHHHHHHHEEHHHHHHHCCCCCEEECCCCCHHH
LEVGLVLPAVGYAAERIAGVPFDEKARVVANEDGRVVDPVRRTVFPGEYVVGWARSGPQG
EEHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEECHHHHHCCCCCEEEEECCCCCCC
LIGEHRRASANVVAHMFADGAGLEARALPPRHAIDELLRARGVRPVSFVDWARLDEVEVA
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEEHHHHHHCCHHHHH
RGARRGAPRDKLVDVAAMLAILGERE
HHHHCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036; 12071965; 12614197; 12102623 [H]