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The map label for this gene is opuBB [H]

Identifier: 220918469

GI number: 220918469

Start: 3752446

End: 3753915

Strand: Direct

Name: opuBB [H]

Synonym: A2cp1_3373

Alternate gene names: 220918469

Gene position: 3752446-3753915 (Clockwise)

Preceding gene: 220918468

Following gene: 220918472

Centisome position: 74.61

GC content: 76.12

Gene sequence:

>1470_bases
ATGCTCGCGGTGGCCCTCGCCCTCGCCGCGCTGGCGACCCCCGGGGTCCGCGTCGGCTCGAAGGCCTTCACCGAGTCGGT
CGTCCTCGGCGAGATCGTCGCGCAGACCGCCGCGTCGACGGGGACGGCCGCCGTCCACCGCCGGGCGCTCGGCGGGACGC
GGGTGGTTTGGGAGGCGCTCACGCGGGGCGAGATCGACGTCTACCCCGAGTACACCGGCACCCTCGTCCGCGAGATCCTG
GCCGGCGAGCCGATCGCCGACGACGCCGCCCTCCGGCGCGCGCTGTCGGCGCGCGGGGTCGGCGTGGCGGCCGTGCTCGG
CTTCGACAACACCTACGCGCTCGGGATGCGGCGTGCAGCCGCCGAGCGGCTCGGCATCCGGACCATCTCGGACCTGCTCC
GGCACCCCGGGCTCCGGTTCGGCTTCACGAACGAGTTCGTGGACCGCGCCGACGGCTGGCCCGCGCTCCGGTCGCGCTAC
GGCCTCTCGGCGTCGTCGGTGCGCGGGCTCGACCACGACCTCGCCTATCGCGCGCTGGCGGAGGGCGCGCTGGACGTGGT
GGACCTCTACTCGACGGATGCCCAGATCGCCCAGCTCGACCTGTCGGCGCTCGACGACGACCGGCGGGCGTTCCCGCGCT
ACGACGCGGTGATCCTCCAGCGGCTGGATCTCGACGCGCGCGCCCCTGCGGCCGTCGCAGCCATCCGCCGGCTCGCGGGC
ACCATCACCGCGCGAGAGATGACCGCCATGAACGCGCGCGTGCAGCTGGAGCACGCCGACCCCGGCGAGGTGGCGGCGGC
TTTCCTCGCGGAACGGCTCGGGCTCGCGCCGGCACCGGTGGCGACGGACGGGCTCGCGCGCCGCGTCGCCGATCGCACGC
TCGAGCACCTCGTGCTGGTCGCCGTGGCGCTCACCGGCGCGATCCTCGCCGCCGTGCCCCTCGGCATCCTGGCCGCGCGC
CGCCCGCGGCTCGGCCGGCTCGTCCTCGCGATCGTGGGGGTGGTGCAGACCGTCCCCTCGCTCGCGCTCCTCGTGTTCAT
GATCCCGCTCCTCGGGATCGGGGCGCGCCCCGCCATCGCGGCGCTGTTCCTGTACGGGCTCCTGCCGATCGTGCGGAACA
CGCACGCCGGGCTCACCGGGCTGGCCCCGGAGCTGCGGGAGTCGGCCGAGGCCCTCGGGCTTCCGCCGCTCGCCCGGCTC
CGGCGGGTGGAGCTGCCGCTCGCCACCCCCGCCATCCTGGCCGGCGTGAAGACCTCCGCGGTCATCACGGTCGGCACCGC
GACGCTCGGCGCGCTCGTGGGGGCCGGCGGCTACGGCCAGCCCATCCTCACCGGCATCCGGCTGCTGTCGGTGCCGCTCA
TCCTCGAGGGCGCGGTCCCCGCGGCGCTCCTCGCGCTGGGCGTGCAGGGGCTGTTCGATCTGGCCGAGAAGCTCCTCGTG
CCGGCGGGCCTGCGGGCGGAGCGGGGGTGA

Upstream 100 bases:

>100_bases
AGGCGGGGACGCTCGAGGATCTCGCCCGTCACCCCGCCGATCCGTTCGTCGCCCGGTTCGTCGGCGCCCACCGGGCCCTC
GTCCTCCCGGAGGTGCGGTG

Downstream 100 bases:

>100_bases
CCCCCCGGCCCGCCGCGCGCGTCTGCGGCGGCGGCCCAGGCGGTCCACGCGAAGAACGCGGTCAGGCGCCGGAGGTCGTC
GGGGCTGGAGACGAGCCCCG

Product: glycine betaine ABC transporter substrate-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MLAVALALAALATPGVRVGSKAFTESVVLGEIVAQTAASTGTAAVHRRALGGTRVVWEALTRGEIDVYPEYTGTLVREIL
AGEPIADDAALRRALSARGVGVAAVLGFDNTYALGMRRAAAERLGIRTISDLLRHPGLRFGFTNEFVDRADGWPALRSRY
GLSASSVRGLDHDLAYRALAEGALDVVDLYSTDAQIAQLDLSALDDDRRAFPRYDAVILQRLDLDARAPAAVAAIRRLAG
TITAREMTAMNARVQLEHADPGEVAAAFLAERLGLAPAPVATDGLARRVADRTLEHLVLVAVALTGAILAAVPLGILAAR
RPRLGRLVLAIVGVVQTVPSLALLVFMIPLLGIGARPAIAALFLYGLLPIVRNTHAGLTGLAPELRESAEALGLPPLARL
RRVELPLATPAILAGVKTSAVITVGTATLGALVGAGGYGQPILTGIRLLSVPLILEGAVPAALLALGVQGLFDLAEKLLV
PAGLRAERG

Sequences:

>Translated_489_residues
MLAVALALAALATPGVRVGSKAFTESVVLGEIVAQTAASTGTAAVHRRALGGTRVVWEALTRGEIDVYPEYTGTLVREIL
AGEPIADDAALRRALSARGVGVAAVLGFDNTYALGMRRAAAERLGIRTISDLLRHPGLRFGFTNEFVDRADGWPALRSRY
GLSASSVRGLDHDLAYRALAEGALDVVDLYSTDAQIAQLDLSALDDDRRAFPRYDAVILQRLDLDARAPAAVAAIRRLAG
TITAREMTAMNARVQLEHADPGEVAAAFLAERLGLAPAPVATDGLARRVADRTLEHLVLVAVALTGAILAAVPLGILAAR
RPRLGRLVLAIVGVVQTVPSLALLVFMIPLLGIGARPAIAALFLYGLLPIVRNTHAGLTGLAPELRESAEALGLPPLARL
RRVELPLATPAILAGVKTSAVITVGTATLGALVGAGGYGQPILTGIRLLSVPLILEGAVPAALLALGVQGLFDLAEKLLV
PAGLRAERG
>Mature_489_residues
MLAVALALAALATPGVRVGSKAFTESVVLGEIVAQTAASTGTAAVHRRALGGTRVVWEALTRGEIDVYPEYTGTLVREIL
AGEPIADDAALRRALSARGVGVAAVLGFDNTYALGMRRAAAERLGIRTISDLLRHPGLRFGFTNEFVDRADGWPALRSRY
GLSASSVRGLDHDLAYRALAEGALDVVDLYSTDAQIAQLDLSALDDDRRAFPRYDAVILQRLDLDARAPAAVAAIRRLAG
TITAREMTAMNARVQLEHADPGEVAAAFLAERLGLAPAPVATDGLARRVADRTLEHLVLVAVALTGAILAAVPLGILAAR
RPRLGRLVLAIVGVVQTVPSLALLVFMIPLLGIGARPAIAALFLYGLLPIVRNTHAGLTGLAPELRESAEALGLPPLARL
RRVELPLATPAILAGVKTSAVITVGTATLGALVGAGGYGQPILTGIRLLSVPLILEGAVPAALLALGVQGLFDLAEKLLV
PAGLRAERG

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1732

COG function: function code M; Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788449, Length=183, Percent_Identity=40.4371584699454, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1788451, Length=205, Percent_Identity=37.0731707317073, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1788452, Length=299, Percent_Identity=29.0969899665552, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1789033, Length=160, Percent_Identity=33.125, Blast_Score=90, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 50896; Mature: 50896

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAVALALAALATPGVRVGSKAFTESVVLGEIVAQTAASTGTAAVHRRALGGTRVVWEAL
CHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHH
TRGEIDVYPEYTGTLVREILAGEPIADDAALRRALSARGVGVAAVLGFDNTYALGMRRAA
HCCCEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
AERLGIRTISDLLRHPGLRFGFTNEFVDRADGWPALRSRYGLSASSVRGLDHDLAYRALA
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHCCCCHHHHCCCHHHHHHHHHH
EGALDVVDLYSTDAQIAQLDLSALDDDRRAFPRYDAVILQRLDLDARAPAAVAAIRRLAG
HCHHHHHHHHCCCHHHHHHHHHHCCCHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHH
TITAREMTAMNARVQLEHADPGEVAAAFLAERLGLAPAPVATDGLARRVADRTLEHLVLV
HHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
AVALTGAILAAVPLGILAARRPRLGRLVLAIVGVVQTVPSLALLVFMIPLLGIGARPAIA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ALFLYGLLPIVRNTHAGLTGLAPELRESAEALGLPPLARLRRVELPLATPAILAGVKTSA
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHCCCCCE
VITVGTATLGALVGAGGYGQPILTGIRLLSVPLILEGAVPAALLALGVQGLFDLAEKLLV
EEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
PAGLRAERG
CCCCCCCCC
>Mature Secondary Structure
MLAVALALAALATPGVRVGSKAFTESVVLGEIVAQTAASTGTAAVHRRALGGTRVVWEAL
CHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHH
TRGEIDVYPEYTGTLVREILAGEPIADDAALRRALSARGVGVAAVLGFDNTYALGMRRAA
HCCCEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
AERLGIRTISDLLRHPGLRFGFTNEFVDRADGWPALRSRYGLSASSVRGLDHDLAYRALA
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHCCCCHHHHCCCHHHHHHHHHH
EGALDVVDLYSTDAQIAQLDLSALDDDRRAFPRYDAVILQRLDLDARAPAAVAAIRRLAG
HCHHHHHHHHCCCHHHHHHHHHHCCCHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHH
TITAREMTAMNARVQLEHADPGEVAAAFLAERLGLAPAPVATDGLARRVADRTLEHLVLV
HHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
AVALTGAILAAVPLGILAARRPRLGRLVLAIVGVVQTVPSLALLVFMIPLLGIGARPAIA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ALFLYGLLPIVRNTHAGLTGLAPELRESAEALGLPPLARLRRVELPLATPAILAGVKTSA
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHCCCCCE
VITVGTATLGALVGAGGYGQPILTGIRLLSVPLILEGAVPAALLALGVQGLFDLAEKLLV
EEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
PAGLRAERG
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592481; 10216873; 9384377 [H]