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The map label for this gene is trg [H]

Identifier: 220918373

GI number: 220918373

Start: 3645558

End: 3647177

Strand: Reverse

Name: trg [H]

Synonym: A2cp1_3277

Alternate gene names: 220918373

Gene position: 3647177-3645558 (Counterclockwise)

Preceding gene: 220918374

Following gene: 220918369

Centisome position: 72.52

GC content: 78.15

Gene sequence:

>1620_bases
ATGGCCCACGCACGCCCTCCCTCCGCGCGGCCCGCTCGCGGCGCGCTCGCGCGCCTGCGCGACCTGAAGCTCCGGACCAA
GCTGCTCGTCCTGCTCGCGGCCGTGAACGCGGCCTCGGCGGCCGCGTTCGTGACGATCTCGTACCGCGTGCAGGCCGGCG
AGATCCGCGCGGCCGTGGACGACAAGCTGCTCACGGCGGCCCGCGCGGCGGCGCTGTTCCTGGTGCCGTTCCACGACCGG
GTCGACGGCCCCGCCTCGATCACGCCCGAGGAGCACCTCGAGGTGCAGCGGCGCCTCTCCGCGCTCGCGGAGGAGACCGG
CCTCGCCTACCTGTACACGGTCGTCGCGCAGGGCTCCGGGAGCGCGTTCACGTCGTCGAGCGCCACGCGCGAGGAGCTCG
CCTCCGGCACCGGCCCGCGCTTCTTCCAGACCACCACGCACCCGAGCCCGGGCCTGGTGGCGGCGCTCGCGGATCACCGG
GTCCACTTCGACACCTACGTCGATCCCACCGACTCGCTGCGCTCGGTCTACGTGCCGCTCCGCTCGCGCAGCGGCAAGGA
GTTCTTCCTCGGGGTGGACGTCCACACCGCCACGCTGGAGGGCGCGATCCGGGCGGCGCTGTGGCGCGCGCTCGCCACGG
GCGCCGCGGTGCTCGCCCTGGGCCTGCTCGCGTCGGCGCTGATGCTCGGCCCGCTCCTGGCGCGGCTGCAGCGCGTGGGC
GCGACCCTCCACCTGGTGGCGCGCGGCCGGCTGGACGTCGAGCTGGAGGAGGACGGCGGGGCGGACGAGATCGGGCGCGT
GGTCGAGGCGCTCCGCGGGATGGTGGCGGCGCTCTCCGGTGCGGCCGGGAGCATCCGCGGGGCGGCGGACGCGCTCGCCG
CCGGCAGCGGTCAGCTCGCCGGTGGCGCCGCGGCGCTCTCGCAGGCGTCGAGCGAGCAGGCCTCCGAGACCGAGCAGGCC
TCGGCGGCCATGCACGAGATCGCGCGGCACGCGCAGGAGAACGCCGCGGCGGCGGCGCGGACCGGCGAGGCCGCGGCGGG
CGCGGCCCGGGGCGCCCGCGCCGGCGGCGAGGCGGCGGCCCGGACCGCAGCGGCCATGCGCGAGGTGGGCGAGAAGATCT
CGATCGTGGAGGAGATCGCCTACCAGACCAACCTGCTCGCCCTGAACGCGGCCATCGAGGCGGCGCGCGCCGGCGAGCAC
GGGCGCGGCTTCGCGGTGGTGGCGAGCGAGGTGCGCCGGCTCGCCGAGCGGAGCCGGGCGGCGGCCGAGGACATCGGCCG
GCTCACCGCCGCGAGCGTGGACCTCGCCGCGCAGGCCGGGACCGCGCTCGACGCGGTGGTGCCCGAGGTGGAGCGGACCG
CGGCCCTCGTCCAGCAGATCTCGGCCGGCAGCGCCGCGCAGGGGGCGAGCGCCGCGCGGGTGAGCGGCGCGCTGCGGAGC
CTGGAGGAGATCGGCGGCCGGAACGCGGCCGCGGCGGAGGAGCTGTCGTCCACCGCCGAGGAGCTGGCCGCGCAGGCCGA
GGGGCTGCGGGACGCGATCGGCTTCTTCCGCGGCGTGGCCGCCGGGGCGGAGCCCCACCCGCCCTCCGCGCCGCCGCTCC
GGCTCGCGTCGGGGCGGTGA

Upstream 100 bases:

>100_bases
GGCGCGGCCCCGCGGCCGCGCCGGATCTGCTCCCTGCTCCCACATCGACGCCCCGGCGTCCCCTGCGACGGGAGCGCGAG
CCGGGTTAGGACTGAGGTCC

Downstream 100 bases:

>100_bases
GCGGAGCCACCGGCGCCGCTCAGTCGGGCCGGCTCGTTCGCCCCAGCAGCGGCCCGAGCCGCGCCAGCGCCGCGCCGAGC
GCGTCGGGCGTGACCGCGGT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: MCP-III; Ribose and galactose chemoreceptor protein [H]

Number of amino acids: Translated: 539; Mature: 538

Protein sequence:

>539_residues
MAHARPPSARPARGALARLRDLKLRTKLLVLLAAVNAASAAAFVTISYRVQAGEIRAAVDDKLLTAARAAALFLVPFHDR
VDGPASITPEEHLEVQRRLSALAEETGLAYLYTVVAQGSGSAFTSSSATREELASGTGPRFFQTTTHPSPGLVAALADHR
VHFDTYVDPTDSLRSVYVPLRSRSGKEFFLGVDVHTATLEGAIRAALWRALATGAAVLALGLLASALMLGPLLARLQRVG
ATLHLVARGRLDVELEEDGGADEIGRVVEALRGMVAALSGAAGSIRGAADALAAGSGQLAGGAAALSQASSEQASETEQA
SAAMHEIARHAQENAAAAARTGEAAAGAARGARAGGEAAARTAAAMREVGEKISIVEEIAYQTNLLALNAAIEAARAGEH
GRGFAVVASEVRRLAERSRAAAEDIGRLTAASVDLAAQAGTALDAVVPEVERTAALVQQISAGSAAQGASAARVSGALRS
LEEIGGRNAAAAEELSSTAEELAAQAEGLRDAIGFFRGVAAGAEPHPPSAPPLRLASGR

Sequences:

>Translated_539_residues
MAHARPPSARPARGALARLRDLKLRTKLLVLLAAVNAASAAAFVTISYRVQAGEIRAAVDDKLLTAARAAALFLVPFHDR
VDGPASITPEEHLEVQRRLSALAEETGLAYLYTVVAQGSGSAFTSSSATREELASGTGPRFFQTTTHPSPGLVAALADHR
VHFDTYVDPTDSLRSVYVPLRSRSGKEFFLGVDVHTATLEGAIRAALWRALATGAAVLALGLLASALMLGPLLARLQRVG
ATLHLVARGRLDVELEEDGGADEIGRVVEALRGMVAALSGAAGSIRGAADALAAGSGQLAGGAAALSQASSEQASETEQA
SAAMHEIARHAQENAAAAARTGEAAAGAARGARAGGEAAARTAAAMREVGEKISIVEEIAYQTNLLALNAAIEAARAGEH
GRGFAVVASEVRRLAERSRAAAEDIGRLTAASVDLAAQAGTALDAVVPEVERTAALVQQISAGSAAQGASAARVSGALRS
LEEIGGRNAAAAEELSSTAEELAAQAEGLRDAIGFFRGVAAGAEPHPPSAPPLRLASGR
>Mature_538_residues
AHARPPSARPARGALARLRDLKLRTKLLVLLAAVNAASAAAFVTISYRVQAGEIRAAVDDKLLTAARAAALFLVPFHDRV
DGPASITPEEHLEVQRRLSALAEETGLAYLYTVVAQGSGSAFTSSSATREELASGTGPRFFQTTTHPSPGLVAALADHRV
HFDTYVDPTDSLRSVYVPLRSRSGKEFFLGVDVHTATLEGAIRAALWRALATGAAVLALGLLASALMLGPLLARLQRVGA
TLHLVARGRLDVELEEDGGADEIGRVVEALRGMVAALSGAAGSIRGAADALAAGSGQLAGGAAALSQASSEQASETEQAS
AAMHEIARHAQENAAAAARTGEAAAGAARGARAGGEAAARTAAAMREVGEKISIVEEIAYQTNLLALNAAIEAARAGEHG
RGFAVVASEVRRLAERSRAAAEDIGRLTAASVDLAAQAGTALDAVVPEVERTAALVQQISAGSAAQGASAARVSGALRSL
EEIGGRNAAAAEELSSTAEELAAQAEGLRDAIGFFRGVAAGAEPHPPSAPPLRLASGR

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=345, Percent_Identity=35.9420289855072, Blast_Score=159, Evalue=5e-40,
Organism=Escherichia coli, GI2367378, Length=400, Percent_Identity=31.5, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1788195, Length=330, Percent_Identity=33.3333333333333, Blast_Score=139, Evalue=6e-34,
Organism=Escherichia coli, GI1788194, Length=272, Percent_Identity=35.2941176470588, Blast_Score=139, Evalue=7e-34,
Organism=Escherichia coli, GI1789453, Length=313, Percent_Identity=31.3099041533546, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 54968; Mature: 54837

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50885 HAMP ; PS00041 HTH_ARAC_FAMILY_1 ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHARPPSARPARGALARLRDLKLRTKLLVLLAAVNAASAAAFVTISYRVQAGEIRAAVD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEECCHHHHHHH
DKLLTAARAAALFLVPFHDRVDGPASITPEEHLEVQRRLSALAEETGLAYLYTVVAQGSG
HHHHHHHHHHHEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHEEHHHHHCCCC
SAFTSSSATREELASGTGPRFFQTTTHPSPGLVAALADHRVHFDTYVDPTDSLRSVYVPL
CCCCCCCHHHHHHHCCCCCCEEEECCCCCCCHHHHHHCCEEEECCCCCCCHHHHHEEHHH
RSRSGKEFFLGVDVHTATLEGAIRAALWRALATGAAVLALGLLASALMLGPLLARLQRVG
HCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ATLHLVARGRLDVELEEDGGADEIGRVVEALRGMVAALSGAAGSIRGAADALAAGSGQLA
CCEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCC
GGAAALSQASSEQASETEQASAAMHEIARHAQENAAAAARTGEAAAGAARGARAGGEAAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHH
RTAAAMREVGEKISIVEEIAYQTNLLALNAAIEAARAGEHGRGFAVVASEVRRLAERSRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
AAEDIGRLTAASVDLAAQAGTALDAVVPEVERTAALVQQISAGSAAQGASAARVSGALRS
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
LEEIGGRNAAAAEELSSTAEELAAQAEGLRDAIGFFRGVAAGAEPHPPSAPPLRLASGR
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AHARPPSARPARGALARLRDLKLRTKLLVLLAAVNAASAAAFVTISYRVQAGEIRAAVD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEECCHHHHHHH
DKLLTAARAAALFLVPFHDRVDGPASITPEEHLEVQRRLSALAEETGLAYLYTVVAQGSG
HHHHHHHHHHHEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHEEHHHHHCCCC
SAFTSSSATREELASGTGPRFFQTTTHPSPGLVAALADHRVHFDTYVDPTDSLRSVYVPL
CCCCCCCHHHHHHHCCCCCCEEEECCCCCCCHHHHHHCCEEEECCCCCCCHHHHHEEHHH
RSRSGKEFFLGVDVHTATLEGAIRAALWRALATGAAVLALGLLASALMLGPLLARLQRVG
HCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ATLHLVARGRLDVELEEDGGADEIGRVVEALRGMVAALSGAAGSIRGAADALAAGSGQLA
CCEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCC
GGAAALSQASSEQASETEQASAAMHEIARHAQENAAAAARTGEAAAGAARGARAGGEAAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHH
RTAAAMREVGEKISIVEEIAYQTNLLALNAAIEAARAGEHGRGFAVVASEVRRLAERSRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
AAEDIGRLTAASVDLAAQAGTALDAVVPEVERTAALVQQISAGSAAQGASAARVSGALRS
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
LEEIGGRNAAAAEELSSTAEELAAQAEGLRDAIGFFRGVAAGAEPHPPSAPPLRLASGR
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6374654; 9097039; 9278503 [H]