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The map label for this gene is qor [H]

Identifier: 220918307

GI number: 220918307

Start: 3558466

End: 3559434

Strand: Reverse

Name: qor [H]

Synonym: A2cp1_3210

Alternate gene names: 220918307

Gene position: 3559434-3558466 (Counterclockwise)

Preceding gene: 220918309

Following gene: 220918306

Centisome position: 70.77

GC content: 75.13

Gene sequence:

>969_bases
ATGCGCGCGATCCGGTTCCACGAGCACGGCGGCCCCGAGGTCCTGAAGCTGGAGGACGTTACCGTCGGTGATCCCGGGCC
GGGCGAGGCCCGGCTCCACATCGCCGCCGCCGGCGTGAACTTCGTGGACGTGTACCAGCGGTCCGGCCTGTACCCGATGC
AGCTCCCGGCCGGCCTGGGCGTCGAGGCGGCGGGGCGGGTGGAGGCCGTGGGCGCGGGCGTGGACCACTTCCGCCCGGGC
GACCGGGTCGCGTTCGTCGGCGGGCCGGGCTGCTACGCCGAGGCGCGGGTGGTCCCGGCCGACCGGCTGGTGCGCCTGCC
CGACGCGATCTCCGACCGCACCGCGGCCGGCGCCATGCTGAAGGGGCTCACGGCGCAGGTGCTCATCCGGCGCACCTACC
CGGTGAAGGCGGGCGACGTGGTCCTCTGGCATGCGGCGGCAGGTGGGGTCGGGCTCATCGCGATCCAGTGGCTGAAGGCG
CTCGGCGCGACCGTGATCGGCACGGTGGGCAGCGACGAGAAGGCGGCGCTGGCGCGCGCCCACGGCTGCGACCACGCCAT
CGTGTACACGCGCGAGGACTTCGTGGCGCGGGTGCGGGAGATCACCGGCGGCGAGGGCGTGCCGGTGGTGTACGACTCGG
TCGGCAAGACCACCTTCGCCGGCTCCATCGACTGCCTGCGGCCGCTCGGCATGATGGTGACGTTCGGCAACGCGTCCGGG
CCGGTGCCGCCGCTGGACCCGCTGCTGCTCTCGCGCAAGGGCTCGCTGTACCTCACGCGGCCGAGCGTGTTCACCTACGT
GGCGCGGCGCGCGGATCTGGAGCGCAGCGCCGCCGAGCTGCTCGAGGTGGTCGGGAGCGGGGCGGTGAAGGTGGAGGTCG
GCCGCGCGCTGCCGCTGGCGCAGGCGGCCGAGGCGCACCGCGCGCTGGAGGCGCGCGCCACCACGGGCTCGCTGGTGCTC
GAGCCGTAG

Upstream 100 bases:

>100_bases
AATCTCGGCACGCCGCCCCGCCCGCGCCTGCCCGCCTGCCCGCCCCGCCTGCGGCGAACCGGGCGGTGCGAGCGCACGCC
GGCCGGGTTAGGACGGATGC

Downstream 100 bases:

>100_bases
CCGGCGCGGCGTGGTCCTCACGGCGATCGTGCGTGACGCGCGGCGTCGCGCACGCACACCCTTCCACCCGGGCCCGCGCG
CGTCTAGGATTCCGCCCCCG

Product: alcohol dehydrogenase zinc-binding domain-containing protein

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MRAIRFHEHGGPEVLKLEDVTVGDPGPGEARLHIAAAGVNFVDVYQRSGLYPMQLPAGLGVEAAGRVEAVGAGVDHFRPG
DRVAFVGGPGCYAEARVVPADRLVRLPDAISDRTAAGAMLKGLTAQVLIRRTYPVKAGDVVLWHAAAGGVGLIAIQWLKA
LGATVIGTVGSDEKAALARAHGCDHAIVYTREDFVARVREITGGEGVPVVYDSVGKTTFAGSIDCLRPLGMMVTFGNASG
PVPPLDPLLLSRKGSLYLTRPSVFTYVARRADLERSAAELLEVVGSGAVKVEVGRALPLAQAAEAHRALEARATTGSLVL
EP

Sequences:

>Translated_322_residues
MRAIRFHEHGGPEVLKLEDVTVGDPGPGEARLHIAAAGVNFVDVYQRSGLYPMQLPAGLGVEAAGRVEAVGAGVDHFRPG
DRVAFVGGPGCYAEARVVPADRLVRLPDAISDRTAAGAMLKGLTAQVLIRRTYPVKAGDVVLWHAAAGGVGLIAIQWLKA
LGATVIGTVGSDEKAALARAHGCDHAIVYTREDFVARVREITGGEGVPVVYDSVGKTTFAGSIDCLRPLGMMVTFGNASG
PVPPLDPLLLSRKGSLYLTRPSVFTYVARRADLERSAAELLEVVGSGAVKVEVGRALPLAQAAEAHRALEARATTGSLVL
EP
>Mature_322_residues
MRAIRFHEHGGPEVLKLEDVTVGDPGPGEARLHIAAAGVNFVDVYQRSGLYPMQLPAGLGVEAAGRVEAVGAGVDHFRPG
DRVAFVGGPGCYAEARVVPADRLVRLPDAISDRTAAGAMLKGLTAQVLIRRTYPVKAGDVVLWHAAAGGVGLIAIQWLKA
LGATVIGTVGSDEKAALARAHGCDHAIVYTREDFVARVREITGGEGVPVVYDSVGKTTFAGSIDCLRPLGMMVTFGNASG
PVPPLDPLLLSRKGSLYLTRPSVFTYVARRADLERSAAELLEVVGSGAVKVEVGRALPLAQAAEAHRALEARATTGSLVL
EP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=330, Percent_Identity=32.1212121212121, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI22538444, Length=330, Percent_Identity=32.1212121212121, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI194239674, Length=327, Percent_Identity=29.3577981651376, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI13236495, Length=327, Percent_Identity=29.3577981651376, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI18379349, Length=309, Percent_Identity=30.0970873786408, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI194239676, Length=326, Percent_Identity=30.0613496932515, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI24308257, Length=345, Percent_Identity=26.6666666666667, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI28557745, Length=322, Percent_Identity=31.3664596273292, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI197927207, Length=188, Percent_Identity=24.468085106383, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1790485, Length=323, Percent_Identity=49.8452012383901, Blast_Score=303, Evalue=1e-83,
Organism=Caenorhabditis elegans, GI17556000, Length=281, Percent_Identity=29.5373665480427, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17507255, Length=324, Percent_Identity=25, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17536829, Length=252, Percent_Identity=29.7619047619048, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6319520, Length=324, Percent_Identity=36.7283950617284, Blast_Score=204, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6323729, Length=352, Percent_Identity=24.4318181818182, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319621, Length=267, Percent_Identity=28.0898876404494, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 33648; Mature: 33648

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAIRFHEHGGPEVLKLEDVTVGDPGPGEARLHIAAAGVNFVDVYQRSGLYPMQLPAGLG
CCCEEEECCCCCCEEEEEEEECCCCCCCCEEEEEEECCCCHHHHHHHCCCCEEECCCCCC
VEAAGRVEAVGAGVDHFRPGDRVAFVGGPGCYAEARVVPADRLVRLPDAISDRTAAGAML
CCCCCCEEEECCCHHHCCCCCEEEEEECCCCCCCEEECCHHHHEECCCHHCCHHHHHHHH
KGLTAQVLIRRTYPVKAGDVVLWHAAAGGVGLIAIQWLKALGATVIGTVGSDEKAALARA
HCCCEEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCCHHHHHHH
HGCDHAIVYTREDFVARVREITGGEGVPVVYDSVGKTTFAGSIDCLRPLGMMVTFGNASG
CCCCEEEEEECHHHHHHHHHHCCCCCCCEEEECCCCEEECCCHHHHHCCCEEEEECCCCC
PVPPLDPLLLSRKGSLYLTRPSVFTYVARRADLERSAAELLEVVGSGAVKVEVGRALPLA
CCCCCCHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHH
QAAEAHRALEARATTGSLVLEP
HHHHHHHHHHHCCCCCCEEECC
>Mature Secondary Structure
MRAIRFHEHGGPEVLKLEDVTVGDPGPGEARLHIAAAGVNFVDVYQRSGLYPMQLPAGLG
CCCEEEECCCCCCEEEEEEEECCCCCCCCEEEEEEECCCCHHHHHHHCCCCEEECCCCCC
VEAAGRVEAVGAGVDHFRPGDRVAFVGGPGCYAEARVVPADRLVRLPDAISDRTAAGAML
CCCCCCEEEECCCHHHCCCCCEEEEEECCCCCCCEEECCHHHHEECCCHHCCHHHHHHHH
KGLTAQVLIRRTYPVKAGDVVLWHAAAGGVGLIAIQWLKALGATVIGTVGSDEKAALARA
HCCCEEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCCHHHHHHH
HGCDHAIVYTREDFVARVREITGGEGVPVVYDSVGKTTFAGSIDCLRPLGMMVTFGNASG
CCCCEEEEEECHHHHHHHHHHCCCCCCCEEEECCCCEEECCCHHHHHCCCEEEEECCCCC
PVPPLDPLLLSRKGSLYLTRPSVFTYVARRADLERSAAELLEVVGSGAVKVEVGRALPLA
CCCCCCHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHH
QAAEAHRALEARATTGSLVLEP
HHHHHHHHHHHCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]