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The map label for this gene is tfdR [H]

Identifier: 220917586

GI number: 220917586

Start: 2747439

End: 2747711

Strand: Direct

Name: tfdR [H]

Synonym: A2cp1_2486

Alternate gene names: 220917586

Gene position: 2747439-2747711 (Clockwise)

Preceding gene: 220917582

Following gene: 220917588

Centisome position: 54.63

GC content: 72.89

Gene sequence:

>273_bases
GTGAGCCTCACGTACATCCAGTCCTTCGTCGCGGTCGCGGAGGAGGGCCACGTCGGCCGCGCCGCCCGGAAGCTTCACCT
CACGCAGCCGCCCCTGTCGCGACACATCCTCGCGCTCGAGGACGAGCTCGGGACGCGCCTGTTCGAGCGGACGCCGCGCG
GCATGCGGCTCCTCCCCGCCGGCGAGGTGTTCCTCTCCCACGCACGGCGGATCCTGGCGGAGGTGGACGTCGCGATCGAG
CGGACGAAGGGCGCGGGCGGCAGCGACGACTGA

Upstream 100 bases:

>100_bases
CCAATACCGTCTCGGTATCCGGGAGGCCGCTCGCGGGCCTCCGAGGCCAGGCCGCCGCTGGGACCTGACACACGGAGCGT
CGTTCAGGTAGGTTCGGCCC

Downstream 100 bases:

>100_bases
CGGTGGAGCGCAGCTCGCGAGACCGTGGAGGAGGCGCGGGGGGCCGCGCACTGCCGCCCCAAGGAATCGAGGGGCGAGTC
GCGAAGTAAAGATGTGGCCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 90; Mature: 89

Protein sequence:

>90_residues
MSLTYIQSFVAVAEEGHVGRAARKLHLTQPPLSRHILALEDELGTRLFERTPRGMRLLPAGEVFLSHARRILAEVDVAIE
RTKGAGGSDD

Sequences:

>Translated_90_residues
MSLTYIQSFVAVAEEGHVGRAARKLHLTQPPLSRHILALEDELGTRLFERTPRGMRLLPAGEVFLSHARRILAEVDVAIE
RTKGAGGSDD
>Mature_89_residues
SLTYIQSFVAVAEEGHVGRAARKLHLTQPPLSRHILALEDELGTRLFERTPRGMRLLPAGEVFLSHARRILAEVDVAIER
TKGAGGSDD

Specific function: Involved in the regulation of 3-chlorocatechol degradation. Transcriptional regulator of tfdB expression. Acts as a repressor in the absence of its effector (either 2-cis- chlorodiene lactone or chloromaleylacetate) but acts as an activator when its effec

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=83, Percent_Identity=49.3975903614458, Blast_Score=78, Evalue=1e-16,
Organism=Escherichia coli, GI2367136, Length=84, Percent_Identity=44.047619047619, Blast_Score=74, Evalue=3e-15,
Organism=Escherichia coli, GI87081904, Length=76, Percent_Identity=47.3684210526316, Blast_Score=69, Evalue=4e-14,
Organism=Escherichia coli, GI157672245, Length=71, Percent_Identity=49.2957746478873, Blast_Score=66, Evalue=4e-13,
Organism=Escherichia coli, GI1790399, Length=86, Percent_Identity=41.8604651162791, Blast_Score=61, Evalue=1e-11,
Organism=Escherichia coli, GI1787806, Length=78, Percent_Identity=44.8717948717949, Blast_Score=59, Evalue=4e-11,
Organism=Escherichia coli, GI1787601, Length=82, Percent_Identity=41.4634146341463, Blast_Score=59, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 9904; Mature: 9772

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTYIQSFVAVAEEGHVGRAARKLHLTQPPLSRHILALEDELGTRLFERTPRGMRLLPA
CCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEECCH
GEVFLSHARRILAEVDVAIERTKGAGGSDD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SLTYIQSFVAVAEEGHVGRAARKLHLTQPPLSRHILALEDELGTRLFERTPRGMRLLPA
CHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEECCH
GEVFLSHARRILAEVDVAIERTKGAGGSDD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8157603; 3413113 [H]