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The map label for this gene is hutI

Identifier: 220917548

GI number: 220917548

Start: 2706764

End: 2708029

Strand: Direct

Name: hutI

Synonym: A2cp1_2448

Alternate gene names: 220917548

Gene position: 2706764-2708029 (Clockwise)

Preceding gene: 220917547

Following gene: 220917549

Centisome position: 53.82

GC content: 77.41

Gene sequence:

>1266_bases
GTGAGCCGCCCCACCGCGACCCTGGTCCTCCGCAACGCCGTCGTCGCCACCTGCGACCGCAGCCCCTCCGACGCCGGCCT
GCTCCCCGGGGCCGCGGTGGCCGTGGAGGGGCGGCGCGTCGCGTGGGTCGGCCGCGACCGCGATCTCGAGGCCGAGGTGA
ACGCGGGGGGCGCGCAGGTGATCGACGCCCGCGGCGGCCTCGTCACCCCGGGGCTGGTGGACTCGCACACGCACCTGGTC
TTCGCGGGCGAGCGCGCGGGCGAGTTCGCGCTCCGCTGCGCCGGGCGCAGCTACCTGCAGGTGGCGCTGTCCGGCGGCGG
GATCGCGGTCACCACCCGCGCGACCCGCGCCGCGCCGGACGAGCAGCTGCTCGCGGACGCCGCCGCCCGCGCCCGCCGCC
TCATCGCCCAGGGCGTCACCACCATCGAGGTGAAGAGCGGCTACGGCCTGGACGCCCCGGAGGAGCTGCGGCTCCTGCGG
ATCGTCCACCAGCTCGGCGACGCGCTCGGCGGAGACGCGACCATCCTGCCCACGCTGCTGTTCCACGCGGTGCCGCCGGA
GCAGGTCGGCGACCGGGCCGCGTTCGTGCGCGAGGCGTGCGCCGCGCTCATCCCCCAGGTCGCGCGCGAGCGGCTGGCGG
TGTTCTGCGACGTGTTCGTGGAGGACGGCGCCTTCGCGCCCGACGAGGCCCGGCGGCTGCTGCAGGCCGCGAAGGACCGC
GGGCTGGTGCCGCGCGTCCACGCCGAGCAGCTCACCGCGGGCGGCGGCGCGCGGCTGGCGGCGGAGCTCGGCTGCGCGAG
CGCCGATCACCTCGAGGAGCTGGACGACGCGGGGGTCGCCGCGCTGGCGGAGGCGCGCGTGGTGGCCGGGCTGCTGCCCC
TCTCGACGCTGTTCCTCGGGTCGGAGCGGTACGCGCCGGCGCGGCGGCTGCTCGAGGCGGGCGTGCCGGTCTCGCTCGCC
ACGAACATGAACCCCGGCAGCGCCATGAGCGAGAACGTCGGGCTCACCCTGTCGCTGGCCTGCCTGAAGCTCGGGCTGAC
GCCCGCGGAGGCGCTGGTCGCGTTCACCGCCGGCGGCGCGAGGGCGCTGCGCCAGCCGGACCTGGGCCGCATCGCGCGCG
GCGCCGACGCCGACCTCGTGTTGTGGGGCTGCGGCTCGCCCGAGCACCTGGCCTGGCACATGGCCGTGAACCACGCGCTC
GTGGTGGTGAAGCACGGGCGGGTGGTGCACGAGGCGCCGTCCGCCGCGATGGTGGACTGCCGCTGA

Upstream 100 bases:

>100_bases
GGGTGCTGCGCAGCGACCCGGCCATGGGGGTGCTCCGTCACGCGGACGCGGGCTATCCGGAGGCCGAGCGCGTCGCGCGG
GAACGGGGTATCAAGCTCCC

Downstream 100 bases:

>100_bases
GGTGCGCGTGCGGGTCGGGCTGCTCTCGGACACGCACGGCCTGCTCGACCCCGCCCTGCCCGCGCTGTTCCGCGGCTGCG
CCCTGCTGGTCCACGCCGGC

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MSRPTATLVLRNAVVATCDRSPSDAGLLPGAAVAVEGRRVAWVGRDRDLEAEVNAGGAQVIDARGGLVTPGLVDSHTHLV
FAGERAGEFALRCAGRSYLQVALSGGGIAVTTRATRAAPDEQLLADAAARARRLIAQGVTTIEVKSGYGLDAPEELRLLR
IVHQLGDALGGDATILPTLLFHAVPPEQVGDRAAFVREACAALIPQVARERLAVFCDVFVEDGAFAPDEARRLLQAAKDR
GLVPRVHAEQLTAGGGARLAAELGCASADHLEELDDAGVAALAEARVVAGLLPLSTLFLGSERYAPARRLLEAGVPVSLA
TNMNPGSAMSENVGLTLSLACLKLGLTPAEALVAFTAGGARALRQPDLGRIARGADADLVLWGCGSPEHLAWHMAVNHAL
VVVKHGRVVHEAPSAAMVDCR

Sequences:

>Translated_421_residues
MSRPTATLVLRNAVVATCDRSPSDAGLLPGAAVAVEGRRVAWVGRDRDLEAEVNAGGAQVIDARGGLVTPGLVDSHTHLV
FAGERAGEFALRCAGRSYLQVALSGGGIAVTTRATRAAPDEQLLADAAARARRLIAQGVTTIEVKSGYGLDAPEELRLLR
IVHQLGDALGGDATILPTLLFHAVPPEQVGDRAAFVREACAALIPQVARERLAVFCDVFVEDGAFAPDEARRLLQAAKDR
GLVPRVHAEQLTAGGGARLAAELGCASADHLEELDDAGVAALAEARVVAGLLPLSTLFLGSERYAPARRLLEAGVPVSLA
TNMNPGSAMSENVGLTLSLACLKLGLTPAEALVAFTAGGARALRQPDLGRIARGADADLVLWGCGSPEHLAWHMAVNHAL
VVVKHGRVVHEAPSAAMVDCR
>Mature_420_residues
SRPTATLVLRNAVVATCDRSPSDAGLLPGAAVAVEGRRVAWVGRDRDLEAEVNAGGAQVIDARGGLVTPGLVDSHTHLVF
AGERAGEFALRCAGRSYLQVALSGGGIAVTTRATRAAPDEQLLADAAARARRLIAQGVTTIEVKSGYGLDAPEELRLLRI
VHQLGDALGGDATILPTLLFHAVPPEQVGDRAAFVREACAALIPQVARERLAVFCDVFVEDGAFAPDEARRLLQAAKDRG
LVPRVHAEQLTAGGGARLAAELGCASADHLEELDDAGVAALAEARVVAGLLPLSTLFLGSERYAPARRLLEAGVPVSLAT
NMNPGSAMSENVGLTLSLACLKLGLTPAEALVAFTAGGARALRQPDLGRIARGADADLVLWGCGSPEHLAWHMAVNHALV
VVKHGRVVHEAPSAAMVDCR

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family

Homologues:

Organism=Homo sapiens, GI223972677, Length=363, Percent_Identity=35.2617079889807, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17555004, Length=407, Percent_Identity=32.4324324324324, Blast_Score=209, Evalue=3e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HUTI_ANAD2 (B8JBF9)

Other databases:

- EMBL:   CP001359
- RefSeq:   YP_002492852.1
- ProteinModelPortal:   B8JBF9
- SMR:   B8JBF9
- GeneID:   7300108
- GenomeReviews:   CP001359_GR
- KEGG:   acp:A2cp1_2448
- HOGENOM:   HBG686142
- ProtClustDB:   PRK09356
- GO:   GO:0005737
- HAMAP:   MF_00372
- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01224

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.2.7

Molecular weight: Translated: 43732; Mature: 43600

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: BINDING 85-85 BINDING 98-98 BINDING 148-148 BINDING 182-182 BINDING 250-250

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPTATLVLRNAVVATCDRSPSDAGLLPGAAVAVEGRRVAWVGRDRDLEAEVNAGGAQV
CCCCHHHHEEHHHEEEECCCCCCCCCCCCCCEEEECCCEEEEECCCCCCCEEECCCCEEE
IDARGGLVTPGLVDSHTHLVFAGERAGEFALRCAGRSYLQVALSGGGIAVTTRATRAAPD
EECCCCCCCCCCCCCCEEEEEECCCCCCHHEECCCCCEEEEEEECCCEEEEECCCCCCCH
EQLLADAAARARRLIAQGVTTIEVKSGYGLDAPEELRLLRIVHQLGDALGGDATILPTLL
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
FHAVPPEQVGDRAAFVREACAALIPQVARERLAVFCDVFVEDGAFAPDEARRLLQAAKDR
HHCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHC
GLVPRVHAEQLTAGGGARLAAELGCASADHLEELDDAGVAALAEARVVAGLLPLSTLFLG
CCCCCCCHHHHCCCCCCHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
SERYAPARRLLEAGVPVSLATNMNPGSAMSENVGLTLSLACLKLGLTPAEALVAFTAGGA
CCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEEEEHHHHCCCHHHHHEEEECCCH
RALRQPDLGRIARGADADLVLWGCGSPEHLAWHMAVNHALVVVKHGRVVHEAPSAAMVDC
HHHCCCCHHHHHCCCCCCEEEECCCCCCCEEEEEEECCEEEEEECCEEEECCCCCCEECC
R
C
>Mature Secondary Structure 
SRPTATLVLRNAVVATCDRSPSDAGLLPGAAVAVEGRRVAWVGRDRDLEAEVNAGGAQV
CCCHHHHEEHHHEEEECCCCCCCCCCCCCCEEEECCCEEEEECCCCCCCEEECCCCEEE
IDARGGLVTPGLVDSHTHLVFAGERAGEFALRCAGRSYLQVALSGGGIAVTTRATRAAPD
EECCCCCCCCCCCCCCEEEEEECCCCCCHHEECCCCCEEEEEEECCCEEEEECCCCCCCH
EQLLADAAARARRLIAQGVTTIEVKSGYGLDAPEELRLLRIVHQLGDALGGDATILPTLL
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
FHAVPPEQVGDRAAFVREACAALIPQVARERLAVFCDVFVEDGAFAPDEARRLLQAAKDR
HHCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHC
GLVPRVHAEQLTAGGGARLAAELGCASADHLEELDDAGVAALAEARVVAGLLPLSTLFLG
CCCCCCCHHHHCCCCCCHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
SERYAPARRLLEAGVPVSLATNMNPGSAMSENVGLTLSLACLKLGLTPAEALVAFTAGGA
CCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEEEEHHHHCCCHHHHHEEEECCCH
RALRQPDLGRIARGADADLVLWGCGSPEHLAWHMAVNHALVVVKHGRVVHEAPSAAMVDC
HHHCCCCHHHHHCCCCCCEEEECCCCCCCEEEEEEECCEEEEEECCEEEECCCCCCEECC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA