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The map label for this gene is apbE [H]

Identifier: 220917480

GI number: 220917480

Start: 2639461

End: 2640567

Strand: Direct

Name: apbE [H]

Synonym: A2cp1_2380

Alternate gene names: 220917480

Gene position: 2639461-2640567 (Clockwise)

Preceding gene: 220917472

Following gene: 220917490

Centisome position: 52.48

GC content: 78.5

Gene sequence:

>1107_bases
GTGAACGTCGATGTAGACATCCTGCCGCACGCGGTCAAGCGTCGCGGGCTGGAGGCCGGCGCGGTGGCAGGCGGACAGGC
GCGCGGATATGCCCTGGCATCCGTGCTCGCCCTCCCCGCCCTCCCCGCCCTGCTCGCCCTCCTCGCGCTCGCGCCTCCCC
CGGAGGGCGAGCTCCGCGAGTCGCGCCCGGGGATGGGAACCCTGCTCACGGTCGCGGTGGTGGCGCCACCGGAGCGCGCC
CGCGCCGGCATCGACGCCGCGTTCGCGGTGTTCGACCGGGTCGACCGGGTGATGAACGAGTGGCGGCCCGACTCGCCGCT
GTCGCGGCTGAACGCCCGCGCCGGGCGGGGCTGGGTGGCCCTGCCCGCGGATCTGTGCGAGGTGCTCCGGATCGCCCGGC
GGGGCGCCCGCGAGACCGGTGGCCTGTTCGATCCCACCTGGGCGGCCGTCTCGGACCTCTGGCGCTTCGACGGCACCGAG
CAGGCGCCCCCGCCCGACGAGGCGGTGCGGGCGCGGTGTGCGCTCGTCGGCTGGCGCGGGCTCGAGCTGCGCGCGCGCCG
CGGCGACGCGGGGTGCGAGGCGCGCCTCGTGCGCGCCGGGATGAAGGTGGGCCTCGGCGGGCTGGCGAAGGGCTGGGCGG
TGGACCACGCCGCCCGGCGCCTCCGCGCGCTCGGGCTCCGGAACTTCCTGCTCCAGGCGGGCGGGGACCTGTACGCCGCG
GGGCGGCGCGGCGGCGCGCCGTGGCACGTCGCGATCCGGGACCCGCGCGGCGGCCCGCTCGACGCGATGGCCGCACTCGA
CGTCTCCGACCGCGCCTTCTCCACCAGCGGCGACTACGAGCACGCCTTCGAGGCGGGCGGGAAGCGCTACCACCACCTCA
TCGATCCGCGCACCTGCCGGCCCTCGCCGGCCAGCCGCGCGGTCACGGTGCTGGCTCGCACCGCCGTGGAGGCCGAGATC
CTGGGCAAGGCGGCGTTCCTGGAGGGCGGCGAGGCCGGGCTGGCGCGCGTCGAGGCGGCCGGGGCCGCGGCGATCCTGGT
GGGCGGCGATGGCGCGGTGCGCGTCTCGCCGGCGCTCGCCGGCCGGCTGGTGCGCGCGCCGCGCTGA

Upstream 100 bases:

>100_bases
GCGGCGAGGATGGCCCGGGCGGTCTCCTCGCGGAGCCGCTCGCGCAGGCGGGGGACCTCTTGTGAACGCGTGTTCATGAT
GCTGAATCCAGATTCATCAC

Downstream 100 bases:

>100_bases
CGCACCGTCCATCTCACCGTCAATCGCGCCGCGGCGCCCCGGGCACCCGCTGCGGGCTCGCGCCGTCCGCGGCCGCGGCG
CGGCGCACGTGCGCCTCGGC

Product: ApbE family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MNVDVDILPHAVKRRGLEAGAVAGGQARGYALASVLALPALPALLALLALAPPPEGELRESRPGMGTLLTVAVVAPPERA
RAGIDAAFAVFDRVDRVMNEWRPDSPLSRLNARAGRGWVALPADLCEVLRIARRGARETGGLFDPTWAAVSDLWRFDGTE
QAPPPDEAVRARCALVGWRGLELRARRGDAGCEARLVRAGMKVGLGGLAKGWAVDHAARRLRALGLRNFLLQAGGDLYAA
GRRGGAPWHVAIRDPRGGPLDAMAALDVSDRAFSTSGDYEHAFEAGGKRYHHLIDPRTCRPSPASRAVTVLARTAVEAEI
LGKAAFLEGGEAGLARVEAAGAAAILVGGDGAVRVSPALAGRLVRAPR

Sequences:

>Translated_368_residues
MNVDVDILPHAVKRRGLEAGAVAGGQARGYALASVLALPALPALLALLALAPPPEGELRESRPGMGTLLTVAVVAPPERA
RAGIDAAFAVFDRVDRVMNEWRPDSPLSRLNARAGRGWVALPADLCEVLRIARRGARETGGLFDPTWAAVSDLWRFDGTE
QAPPPDEAVRARCALVGWRGLELRARRGDAGCEARLVRAGMKVGLGGLAKGWAVDHAARRLRALGLRNFLLQAGGDLYAA
GRRGGAPWHVAIRDPRGGPLDAMAALDVSDRAFSTSGDYEHAFEAGGKRYHHLIDPRTCRPSPASRAVTVLARTAVEAEI
LGKAAFLEGGEAGLARVEAAGAAAILVGGDGAVRVSPALAGRLVRAPR
>Mature_368_residues
MNVDVDILPHAVKRRGLEAGAVAGGQARGYALASVLALPALPALLALLALAPPPEGELRESRPGMGTLLTVAVVAPPERA
RAGIDAAFAVFDRVDRVMNEWRPDSPLSRLNARAGRGWVALPADLCEVLRIARRGARETGGLFDPTWAAVSDLWRFDGTE
QAPPPDEAVRARCALVGWRGLELRARRGDAGCEARLVRAGMKVGLGGLAKGWAVDHAARRLRALGLRNFLLQAGGDLYAA
GRRGGAPWHVAIRDPRGGPLDAMAALDVSDRAFSTSGDYEHAFEAGGKRYHHLIDPRTCRPSPASRAVTVLARTAVEAEI
LGKAAFLEGGEAGLARVEAAGAAAILVGGDGAVRVSPALAGRLVRAPR

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=282, Percent_Identity=29.7872340425532, Blast_Score=114, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 38641; Mature: 38641

Theoretical pI: Translated: 10.51; Mature: 10.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVDVDILPHAVKRRGLEAGAVAGGQARGYALASVLALPALPALLALLALAPPPEGELRE
CCCCHHHCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
SRPGMGTLLTVAVVAPPERARAGIDAAFAVFDRVDRVMNEWRPDSPLSRLNARAGRGWVA
CCCCCCEEEEEEEECCCHHHHHCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEE
LPADLCEVLRIARRGARETGGLFDPTWAAVSDLWRFDGTEQAPPPDEAVRARCALVGWRG
CHHHHHHHHHHHHHCCHHCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCC
LELRARRGDAGCEARLVRAGMKVGLGGLAKGWAVDHAARRLRALGLRNFLLQAGGDLYAA
CEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
GRRGGAPWHVAIRDPRGGPLDAMAALDVSDRAFSTSGDYEHAFEAGGKRYHHLIDPRTCR
CCCCCCCEEEEEECCCCCCCHHHHEECCCCCCCCCCCCHHHHHHCCCCEEHHCCCCCCCC
PSPASRAVTVLARTAVEAEILGKAAFLEGGEAGLARVEAAGAAAILVGGDGAVRVSPALA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCEEEEECCCCCEEECHHHH
GRLVRAPR
HHHHCCCC
>Mature Secondary Structure
MNVDVDILPHAVKRRGLEAGAVAGGQARGYALASVLALPALPALLALLALAPPPEGELRE
CCCCHHHCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
SRPGMGTLLTVAVVAPPERARAGIDAAFAVFDRVDRVMNEWRPDSPLSRLNARAGRGWVA
CCCCCCEEEEEEEECCCHHHHHCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEE
LPADLCEVLRIARRGARETGGLFDPTWAAVSDLWRFDGTEQAPPPDEAVRARCALVGWRG
CHHHHHHHHHHHHHCCHHCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCC
LELRARRGDAGCEARLVRAGMKVGLGGLAKGWAVDHAARRLRALGLRNFLLQAGGDLYAA
CEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
GRRGGAPWHVAIRDPRGGPLDAMAALDVSDRAFSTSGDYEHAFEAGGKRYHHLIDPRTCR
CCCCCCCEEEEEECCCCCCCHHHHEECCCCCCCCCCCCHHHHHHCCCCEEHHCCCCCCCC
PSPASRAVTVLARTAVEAEILGKAAFLEGGEAGLARVEAAGAAAILVGGDGAVRVSPALA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCEEEEECCCCCEEECHHHH
GRLVRAPR
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]