Click here to switch to the map view.

The map label for this gene is sigC [H]

Identifier: 220917457

GI number: 220917457

Start: 2610383

End: 2611108

Strand: Reverse

Name: sigC [H]

Synonym: A2cp1_2357

Alternate gene names: 220917457

Gene position: 2611108-2610383 (Counterclockwise)

Preceding gene: 220917458

Following gene: 220917456

Centisome position: 51.92

GC content: 70.11

Gene sequence:

>726_bases
ATGAGGACGGCGAGCACGCAGAGAGGCAGCAAGGAGTTCGATGAGCTGGCCCCCTACCTCAAGGCGGTCCGCGACTTCCC
GCCGCTCACCCGCGAGGATGAGCACGCGCTGGCCATCCGGGCACGCAAGGGCGAGGTGTCGGCGAAGCAGAAACTGGTTC
GCCACAACCTCGCGTTCGTGGTCGCCATCGCGCGCAAGCAGCGCCGCGGCACGGTCCGGCTCGACGATCTGATCCAGGAG
GGCAACGTCGGCCTGATGCGCGCCGTCGAGAAGTTCGACCCGCACGCCGGGACGCGCTTCTCGACGTACGCGGTGTGGTG
GATCCGCGCCTACATCGGGAAGTACCTCAAGGAGGCGCGCTCCACGGTGCGGCCGCAGAGCGGCACCGTCGCGCAGCCGG
ACCTGTCGCTCGACAGCGCCATCGACGAGGAGGGGGACGCCACCCACCTCGAGCGCATCGAGGACGACGGTCCCGGGCCG
GAGGACACCTACCTCTCCGGCGAGGGCGACCGCGAGGTCCGCGACGCGCTCGGCAAGGTGCGCAAGCGGATCGGCGAGCT
GGGCTGGGACATCGTCCACAACCGGCTCGAGCAGGACCAGCCGCGCACGCTGGAGGAGATCGGCAAGCGCTGGGGCGTGT
CGCGCGAGCGCGTCCGCCAGGTCGAGCTGAAGACCAAGCAGTTCCTGCACCGGTACCTCCAGCCGGTCGAGCGCGACGCC
GCATAG

Upstream 100 bases:

>100_bases
CCGGGCTACTTGACTGGTTCGGTCCATTATTTTAACCTGACGTTACGTAACCTCCCCGAGATGGATTGACGCAGGACAGG
ACAGGTAGAGAGGCAACGGA

Downstream 100 bases:

>100_bases
CCGCGCGAACGCATCGCACCGCGCCGCCTCGGTCGGCGCACCTCGAGGCCCGCCCCCGCACCGGAGGCGGGCCTCGTCGC
ATCCGGGTGGGGCGGCGGCC

Product: RNA polymerase sigma-32 subunit RpoH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MRTASTQRGSKEFDELAPYLKAVRDFPPLTREDEHALAIRARKGEVSAKQKLVRHNLAFVVAIARKQRRGTVRLDDLIQE
GNVGLMRAVEKFDPHAGTRFSTYAVWWIRAYIGKYLKEARSTVRPQSGTVAQPDLSLDSAIDEEGDATHLERIEDDGPGP
EDTYLSGEGDREVRDALGKVRKRIGELGWDIVHNRLEQDQPRTLEEIGKRWGVSRERVRQVELKTKQFLHRYLQPVERDA
A

Sequences:

>Translated_241_residues
MRTASTQRGSKEFDELAPYLKAVRDFPPLTREDEHALAIRARKGEVSAKQKLVRHNLAFVVAIARKQRRGTVRLDDLIQE
GNVGLMRAVEKFDPHAGTRFSTYAVWWIRAYIGKYLKEARSTVRPQSGTVAQPDLSLDSAIDEEGDATHLERIEDDGPGP
EDTYLSGEGDREVRDALGKVRKRIGELGWDIVHNRLEQDQPRTLEEIGKRWGVSRERVRQVELKTKQFLHRYLQPVERDA
A
>Mature_241_residues
MRTASTQRGSKEFDELAPYLKAVRDFPPLTREDEHALAIRARKGEVSAKQKLVRHNLAFVVAIARKQRRGTVRLDDLIQE
GNVGLMRAVEKFDPHAGTRFSTYAVWWIRAYIGKYLKEARSTVRPQSGTVAQPDLSLDSAIDEEGDATHLERIEDDGPGP
EDTYLSGEGDREVRDALGKVRKRIGELGWDIVHNRLEQDQPRTLEEIGKRWGVSRERVRQVELKTKQFLHRYLQPVERDA
A

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is essential for normal fruiting body formation [H]

COG id: COG0568

COG function: function code K; DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family [H]

Homologues:

Organism=Escherichia coli, GI1789098, Length=286, Percent_Identity=31.1188811188811, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1789448, Length=223, Percent_Identity=28.6995515695067, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789871, Length=102, Percent_Identity=41.1764705882353, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: <10 (log phase) 250 (stationary phase) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000943
- InterPro:   IPR009042
- InterPro:   IPR007627
- InterPro:   IPR007624
- InterPro:   IPR007630
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00140 Sigma70_r1_2; PF04542 Sigma70_r2; PF04539 Sigma70_r3; PF04545 Sigma70_r4 [H]

EC number: NA

Molecular weight: Translated: 27565; Mature: 27565

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS00715 SIGMA70_1 ; PS00716 SIGMA70_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTASTQRGSKEFDELAPYLKAVRDFPPLTREDEHALAIRARKGEVSAKQKLVRHNLAFV
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHH
VAIARKQRRGTVRLDDLIQEGNVGLMRAVEKFDPHAGTRFSTYAVWWIRAYIGKYLKEAR
HHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
STVRPQSGTVAQPDLSLDSAIDEEGDATHLERIEDDGPGPEDTYLSGEGDREVRDALGKV
HHCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHCCCCCCCCCEECCCCCHHHHHHHHHH
RKRIGELGWDIVHNRLEQDQPRTLEEIGKRWGVSRERVRQVELKTKQFLHRYLQPVERDA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
A
C
>Mature Secondary Structure
MRTASTQRGSKEFDELAPYLKAVRDFPPLTREDEHALAIRARKGEVSAKQKLVRHNLAFV
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHH
VAIARKQRRGTVRLDDLIQEGNVGLMRAVEKFDPHAGTRFSTYAVWWIRAYIGKYLKEAR
HHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
STVRPQSGTVAQPDLSLDSAIDEEGDATHLERIEDDGPGPEDTYLSGEGDREVRDALGKV
HHCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHCCCCCCCCCEECCCCCHHHHHHHHHH
RKRIGELGWDIVHNRLEQDQPRTLEEIGKRWGVSRERVRQVELKTKQFLHRYLQPVERDA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501037 [H]