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The map label for this gene is regB [H]

Identifier: 220917444

GI number: 220917444

Start: 2597984

End: 2599342

Strand: Reverse

Name: regB [H]

Synonym: A2cp1_2344

Alternate gene names: 220917444

Gene position: 2599342-2597984 (Counterclockwise)

Preceding gene: 220917447

Following gene: 220917443

Centisome position: 51.68

GC content: 74.03

Gene sequence:

>1359_bases
ATGGCAGCGGGGGACCTGGCGGCGGCGGCCGGGACGGCGCCGCACCCGAACCGGTCCCCTGCGCGCAGCGCCGCCGGCGA
CGAGCGCGGCCGCCTGAACCTGTCGTGGCTCGTCCAGCTTCACTGGTGGGCGATCCTCGGCCAGGCCACCATCGTGGTGG
GCGCGCAGTCGTGGACGCACATCGGCCTGCCCATGGGCACGCTGGTGGCGGTGATGGTCCTGGAGGTCATCGGGAACGTC
GTGCTGGGCGCCTGGGCGCGCCGCGCGCAGGTGACCGACCGGGACATCGCGCTGGTGATGCTGATCGACGCGGCGGTCCT
GACGGTGCTGCTCGACCTGACCGGGGGCGCGTCCAACCCGTTCTCCACGCTCTACCTCGTCAACGTGGCGCTGGCCGCGG
TGCTGCTGCCGTCCGCCTGGTCGTGGCTGCTCATGGCGGCCAGCCTGGCGGGCTTCGCGTCGCTGTTCGTGCACGAGCAC
TTCGCCGGCGTGAGCCACCACATCCGCACCCACATGGACCACGCGCAGACCATGGCCGCGCACCTGCGCGGCATGTGGGT
CGCGTTCGCGCTGGCCGCGGTGTTCGTGGTGTTCTTCGTCCAGCGGGTCACGCGCGCGCTCTCCGCACGCGAGGGTGAGC
TCCAGGCCGCGCGCTCCCAGGCGCAGCGGCGCGAGAAGCTCGCCTCCCTGGCGACGCTCGCCGCGGGTGCGGCGCACGAG
CTCTCCACCCCGCTCTCCACCATCGCGGTGGTCGCGAAGGAGCTGCAGCGCGCCATCCCGGCCGACGCCTCGAGCGAGCT
CCACGACGACCTGCAGCTCGTGCGCGACCAGGTGGCGCGCTGCCGCGAGATCCTCGACCGCATGGCGGCGCACGCCGGCG
AGAACGTGGGCGAGCCGTTCGCGCAGATGCGCGCGCGCGACTGGGTGGACGCCGCGCTGGACGGGTTCCGGTGGCCGCAG
CGCGTGGAGGTGCGGATCGACCCGAGCGCCGAGGCCGCCTCGCTGGTGGGGCCTCAGCGCGGGCTCGCCGAGGCGCTGCG
GGGCCTGCTCAAGAACGCGGTCCAGGCGTCGCCCGCCGAGGCGCAGGTCACGCTGCTCGTCACCGCGCCGCCCGGCCGGA
TCCAGATCACGGTGCGCGACCGGGGCCGCGGCATGACGCCCGAGGTGCTGTCGCGCGTGGGTGAGCCGTTCTTCACGACG
AAGGTCCCCGGGGAGGGGATGGGGCTGGGCCTCTTCCTCACCCGGGCGCTCGCCGAGCAGCTCGGCGGCGAGTTCAACAT
CACCTCCACCCCGGGGGACGGGACGGAGGCGCGTTTCGAGCTGCCGGTGTCGACCGCCGGCGAGAGGAGCAGTCCATGA

Upstream 100 bases:

>100_bases
GTCAAGCCGTGGTGCGACACCGGGCCGCGCCGTGCTCCGGCGGGGCCCCCCTGTGCTAACCTCTCGTCGTTCTCGGGGGA
TTGCCGTGGCGCAAGGAGAG

Downstream 100 bases:

>100_bases
ACACGATGACGCCCGAAGTGACCCGCGAGTCGTTGCCGAGCATCCTGCTGGTGGACGACGACGAGGTGCTGCGCGAGCGG
CTCGCCACCGCCATCCGCGC

Product: histidine kinase

Products: NA

Alternate protein names: Protein prrB [H]

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MAAGDLAAAAGTAPHPNRSPARSAAGDERGRLNLSWLVQLHWWAILGQATIVVGAQSWTHIGLPMGTLVAVMVLEVIGNV
VLGAWARRAQVTDRDIALVMLIDAAVLTVLLDLTGGASNPFSTLYLVNVALAAVLLPSAWSWLLMAASLAGFASLFVHEH
FAGVSHHIRTHMDHAQTMAAHLRGMWVAFALAAVFVVFFVQRVTRALSAREGELQAARSQAQRREKLASLATLAAGAAHE
LSTPLSTIAVVAKELQRAIPADASSELHDDLQLVRDQVARCREILDRMAAHAGENVGEPFAQMRARDWVDAALDGFRWPQ
RVEVRIDPSAEAASLVGPQRGLAEALRGLLKNAVQASPAEAQVTLLVTAPPGRIQITVRDRGRGMTPEVLSRVGEPFFTT
KVPGEGMGLGLFLTRALAEQLGGEFNITSTPGDGTEARFELPVSTAGERSSP

Sequences:

>Translated_452_residues
MAAGDLAAAAGTAPHPNRSPARSAAGDERGRLNLSWLVQLHWWAILGQATIVVGAQSWTHIGLPMGTLVAVMVLEVIGNV
VLGAWARRAQVTDRDIALVMLIDAAVLTVLLDLTGGASNPFSTLYLVNVALAAVLLPSAWSWLLMAASLAGFASLFVHEH
FAGVSHHIRTHMDHAQTMAAHLRGMWVAFALAAVFVVFFVQRVTRALSAREGELQAARSQAQRREKLASLATLAAGAAHE
LSTPLSTIAVVAKELQRAIPADASSELHDDLQLVRDQVARCREILDRMAAHAGENVGEPFAQMRARDWVDAALDGFRWPQ
RVEVRIDPSAEAASLVGPQRGLAEALRGLLKNAVQASPAEAQVTLLVTAPPGRIQITVRDRGRGMTPEVLSRVGEPFFTT
KVPGEGMGLGLFLTRALAEQLGGEFNITSTPGDGTEARFELPVSTAGERSSP
>Mature_451_residues
AAGDLAAAAGTAPHPNRSPARSAAGDERGRLNLSWLVQLHWWAILGQATIVVGAQSWTHIGLPMGTLVAVMVLEVIGNVV
LGAWARRAQVTDRDIALVMLIDAAVLTVLLDLTGGASNPFSTLYLVNVALAAVLLPSAWSWLLMAASLAGFASLFVHEHF
AGVSHHIRTHMDHAQTMAAHLRGMWVAFALAAVFVVFFVQRVTRALSAREGELQAARSQAQRREKLASLATLAAGAAHEL
STPLSTIAVVAKELQRAIPADASSELHDDLQLVRDQVARCREILDRMAAHAGENVGEPFAQMRARDWVDAALDGFRWPQR
VEVRIDPSAEAASLVGPQRGLAEALRGLLKNAVQASPAEAQVTLLVTAPPGRIQITVRDRGRGMTPEVLSRVGEPFFTTK
VPGEGMGLGLFLTRALAEQLGGEFNITSTPGDGTEARFELPVSTAGERSSP

Specific function: Member of the two-component regulatory system RegB/RegA. Involved in the positive regulation of photosynthesis gene expression in response to anaerobiosis. Also involved in positive regulation of the cbbI and cbbII Calvin cycle CO2 fixation operons, as we

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=278, Percent_Identity=28.7769784172662, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788549, Length=252, Percent_Identity=26.1904761904762, Blast_Score=75, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48184; Mature: 48053

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAGDLAAAAGTAPHPNRSPARSAAGDERGRLNLSWLVQLHWWAILGQATIVVGAQSWTH
CCCCCHHHHCCCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCC
IGLPMGTLVAVMVLEVIGNVVLGAWARRAQVTDRDIALVMLIDAAVLTVLLDLTGGASNP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
FSTLYLVNVALAAVLLPSAWSWLLMAASLAGFASLFVHEHFAGVSHHIRTHMDHAQTMAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLRGMWVAFALAAVFVVFFVQRVTRALSAREGELQAARSQAQRREKLASLATLAAGAAHE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LSTPLSTIAVVAKELQRAIPADASSELHDDLQLVRDQVARCREILDRMAAHAGENVGEPF
HHCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
AQMRARDWVDAALDGFRWPQRVEVRIDPSAEAASLVGPQRGLAEALRGLLKNAVQASPAE
HHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCC
AQVTLLVTAPPGRIQITVRDRGRGMTPEVLSRVGEPFFTTKVPGEGMGLGLFLTRALAEQ
CEEEEEEECCCCEEEEEEECCCCCCCHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHH
LGGEFNITSTPGDGTEARFELPVSTAGERSSP
CCCCEEEECCCCCCCCCEEECCCCCCCCCCCC
>Mature Secondary Structure 
AAGDLAAAAGTAPHPNRSPARSAAGDERGRLNLSWLVQLHWWAILGQATIVVGAQSWTH
CCCCHHHHCCCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCC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CCCCEEEECCCCCCCCCEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7751278; 10358089 [H]