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The map label for this gene is trxA [H]

Identifier: 220917442

GI number: 220917442

Start: 2596886

End: 2597284

Strand: Reverse

Name: trxA [H]

Synonym: A2cp1_2342

Alternate gene names: 220917442

Gene position: 2597284-2596886 (Counterclockwise)

Preceding gene: 220917443

Following gene: 220917441

Centisome position: 51.64

GC content: 69.42

Gene sequence:

>399_bases
ATGGCGCACGCGACGGTCGAGATCACCTCGCAGAACTTCAAGGACGTCGTCGAGAAGGACGGCATCGTCCTCATCGACTG
GTGGGCCACCTGGTGCGGCCCGTGCCGGTCGTTCGGCCCCACGTACGAGAAGGTCGCGGGCAAGCACCCGGACCTCACCT
TCGGGAAGGTGAACACCGAGGAGCAGCAGGAGCTCGCGGCGGCGTTCGACATCCGGTCGATCCCCACGCTGATGATCCTG
CGCGACAAGGTGCTGCTCTTCTCGCAGGCCGGCGCGCTGCCCGAGGCCGCGCTGGAGGACCTCATCCGCCAGGTGCGCGC
GCTCGACATGGACAAGGTCCGCGCCGACGTCGCCGCGCAGGAGGCGGAGGCGGCGAAGCGCAGCAGCGCCTCGGCCTGA

Upstream 100 bases:

>100_bases
GGCGGGGGCGCGCGGCGAACCCTTTTCCCCGCGGCGGGGTCGAACTCCGTGTCAGCGCCCCGGAGGCCGATGGACGGCGG
GCGCGGAGAGGCACGGAGAC

Downstream 100 bases:

>100_bases
TCCCGTCCCCCGCGGCCGGCGCAAAGAGGAAGGGCGGATGGCCGCGAGGCCACCCGCCCTTCGAGTCTCCGGGCCTCGCG
GGGCTACTTCGTCCCGCCGG

Product: thioredoxin

Products: NA

Alternate protein names: Trx [H]

Number of amino acids: Translated: 132; Mature: 131

Protein sequence:

>132_residues
MAHATVEITSQNFKDVVEKDGIVLIDWWATWCGPCRSFGPTYEKVAGKHPDLTFGKVNTEEQQELAAAFDIRSIPTLMIL
RDKVLLFSQAGALPEAALEDLIRQVRALDMDKVRADVAAQEAEAAKRSSASA

Sequences:

>Translated_132_residues
MAHATVEITSQNFKDVVEKDGIVLIDWWATWCGPCRSFGPTYEKVAGKHPDLTFGKVNTEEQQELAAAFDIRSIPTLMIL
RDKVLLFSQAGALPEAALEDLIRQVRALDMDKVRADVAAQEAEAAKRSSASA
>Mature_131_residues
AHATVEITSQNFKDVVEKDGIVLIDWWATWCGPCRSFGPTYEKVAGKHPDLTFGKVNTEEQQELAAAFDIRSIPTLMILR
DKVLLFSQAGALPEAALEDLIRQVRALDMDKVRADVAAQEAEAAKRSSASA

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758304, Length=81, Percent_Identity=37.037037037037, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788936, Length=101, Percent_Identity=38.6138613861386, Blast_Score=84, Evalue=2e-18,
Organism=Escherichia coli, GI87082331, Length=104, Percent_Identity=31.7307692307692, Blast_Score=75, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71980562, Length=117, Percent_Identity=29.0598290598291, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71980565, Length=101, Percent_Identity=31.6831683168317, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI212646193, Length=93, Percent_Identity=32.258064516129, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323072, Length=88, Percent_Identity=30.6818181818182, Blast_Score=68, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6319925, Length=92, Percent_Identity=30.4347826086957, Blast_Score=65, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321648, Length=77, Percent_Identity=35.0649350649351, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 14503; Mature: 14371

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHATVEITSQNFKDVVEKDGIVLIDWWATWCGPCRSFGPTYEKVAGKHPDLTFGKVNTE
CCCEEEEECCHHHHHHHHCCCEEEEECHHHHHHHHHCCCCCHHHHCCCCCCCEECCCCCH
EQQELAAAFDIRSIPTLMILRDKVLLFSQAGALPEAALEDLIRQVRALDMDKVRADVAAQ
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
EAEAAKRSSASA
HHHHHHHCCCCC
>Mature Secondary Structure 
AHATVEITSQNFKDVVEKDGIVLIDWWATWCGPCRSFGPTYEKVAGKHPDLTFGKVNTE
CCEEEEECCHHHHHHHHCCCEEEEECHHHHHHHHHCCCCCHHHHCCCCCCCEECCCCCH
EQQELAAAFDIRSIPTLMILRDKVLLFSQAGALPEAALEDLIRQVRALDMDKVRADVAAQ
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
EAEAAKRSSASA
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]