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The map label for this gene is sucC

Identifier: 220917421

GI number: 220917421

Start: 2572355

End: 2573521

Strand: Reverse

Name: sucC

Synonym: A2cp1_2321

Alternate gene names: 220917421

Gene position: 2573521-2572355 (Counterclockwise)

Preceding gene: 220917422

Following gene: 220917420

Centisome position: 51.17

GC content: 69.84

Gene sequence:

>1167_bases
TTGAAGATCCACGAGTACCAGGCGAAGGAAATCCTGCGGAAGTTCGGCGTGGCGGTCCCGCGCGGCTACCTCGCGGTCAC
GCCGCTCGAGGCGGAGGGCGCGGCGCGCCAGCTCGGCGGCGGCATCAGCGCGGTGAAGGCGCAGATCCACGCGGGCGGCC
GCGGCAAGGGCGGCGGCGTGAAGCTGGCCCGCTCGCCGGACGAGGCGCGTCAGCACGCCGAGGCCATGCTCGGCATGATG
CTGAAGACCCCGCAGACCGGGCCGGACGGGCAGGAGGTCCGGAAGGTCTACGTCGAGGAGGGCTGCCGGATCGCCCGCGA
GCTGTACCTCGGCATGACGCTCGACCGCGAGATCGGGCGCCTGGCGGTGATGGCGTCGGTCGAGGGCGGCGTGGACATCG
AGGAGGTGGCCGCGAAGCACCCCGACAAGATCCTGCGGGAGTGGATCTCGCCGCTGACCGGCCTCATGCCGTTCCAGGCC
CGCCGGCTCGCGTTCGGCCTCGGCCTCACCGGCGACTCGGTCACCGCGTTCGTCCGCTTCGCCACCGGCCTGTACAACGC
CTACGTCGCCACCGACGCGTCGCTCGCCGAGATCAACCCGCTCGTCATCACGGTGGGCGGCGAGGTGCTCGCGCTCGACG
CGAAGATGAACTTCGACGACAACGCGCTCTACCGGCACCCGGACATCGCGGCCATGCGCGATCCGGACGAGGAGGATCCG
AAGGAGACGCAGGCCAAGGAGTACGACCTCTCGTACATCGCGCTGGACGGCGACATCGGCTGCATGGTGAACGGCGCCGG
CCTGGCCATGGCCACCATGGACGTGATCAAGCTGTCCGGCGGCCAGCCGGCCAACTTCCTCGACGTGGGCGGCGGCGCCG
ACGAGGACAAGGTCACCGCGGCGTTCAAGATCATCCTCTCCGATCCGCACGTGAAGGCGGTGCTGGTCAACATCTTCGGC
GGCATCATGAAGTGCGACGTGATCGCGAACGGCATCGTCGCCGCCGCCAAGCAGGTGGGGCTCTCCATCCCGCTGGTGGT
CCGGCTCGAGGGCACCAACGTGGAGCTGGGCAAGGACATCCTCGCCCACAGCGAGCTGAAGATCATCCCCGCGGACGACC
TCGGCGACGCTGCCCGGAAGGTCGTCCAGGCCGCGCGAGCCGCCTAG

Upstream 100 bases:

>100_bases
GTCCGTCGCAGAGACCAAGCTGTAGTAGGTTTCTCGGGCCGGTCGTCCACCCCATCCGGGGGCGACCGGCCTTCGTCGTC
CCAACGAGAGCGAGCTCGGC

Downstream 100 bases:

>100_bases
ATCCAGGTCCATTCGTCGCACGAGCGGCGGGAGGCACACGCCTTGAGCATCCTCGTAGATCGCAACACCCGGGTCCTCGT
CCAGGGCATCACCGGCTCGG

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MKIHEYQAKEILRKFGVAVPRGYLAVTPLEAEGAARQLGGGISAVKAQIHAGGRGKGGGVKLARSPDEARQHAEAMLGMM
LKTPQTGPDGQEVRKVYVEEGCRIARELYLGMTLDREIGRLAVMASVEGGVDIEEVAAKHPDKILREWISPLTGLMPFQA
RRLAFGLGLTGDSVTAFVRFATGLYNAYVATDASLAEINPLVITVGGEVLALDAKMNFDDNALYRHPDIAAMRDPDEEDP
KETQAKEYDLSYIALDGDIGCMVNGAGLAMATMDVIKLSGGQPANFLDVGGGADEDKVTAAFKIILSDPHVKAVLVNIFG
GIMKCDVIANGIVAAAKQVGLSIPLVVRLEGTNVELGKDILAHSELKIIPADDLGDAARKVVQAARAA

Sequences:

>Translated_388_residues
MKIHEYQAKEILRKFGVAVPRGYLAVTPLEAEGAARQLGGGISAVKAQIHAGGRGKGGGVKLARSPDEARQHAEAMLGMM
LKTPQTGPDGQEVRKVYVEEGCRIARELYLGMTLDREIGRLAVMASVEGGVDIEEVAAKHPDKILREWISPLTGLMPFQA
RRLAFGLGLTGDSVTAFVRFATGLYNAYVATDASLAEINPLVITVGGEVLALDAKMNFDDNALYRHPDIAAMRDPDEEDP
KETQAKEYDLSYIALDGDIGCMVNGAGLAMATMDVIKLSGGQPANFLDVGGGADEDKVTAAFKIILSDPHVKAVLVNIFG
GIMKCDVIANGIVAAAKQVGLSIPLVVRLEGTNVELGKDILAHSELKIIPADDLGDAARKVVQAARAA
>Mature_388_residues
MKIHEYQAKEILRKFGVAVPRGYLAVTPLEAEGAARQLGGGISAVKAQIHAGGRGKGGGVKLARSPDEARQHAEAMLGMM
LKTPQTGPDGQEVRKVYVEEGCRIARELYLGMTLDREIGRLAVMASVEGGVDIEEVAAKHPDKILREWISPLTGLMPFQA
RRLAFGLGLTGDSVTAFVRFATGLYNAYVATDASLAEINPLVITVGGEVLALDAKMNFDDNALYRHPDIAAMRDPDEEDP
KETQAKEYDLSYIALDGDIGCMVNGAGLAMATMDVIKLSGGQPANFLDVGGGADEDKVTAAFKIILSDPHVKAVLVNIFG
GIMKCDVIANGIVAAAKQVGLSIPLVVRLEGTNVELGKDILAHSELKIIPADDLGDAARKVVQAARAA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=390, Percent_Identity=47.9487179487179, Blast_Score=346, Evalue=2e-95,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=48.3028720626632, Blast_Score=343, Evalue=1e-94,
Organism=Homo sapiens, GI294862256, Length=362, Percent_Identity=48.3425414364641, Blast_Score=330, Evalue=2e-90,
Organism=Escherichia coli, GI1786948, Length=384, Percent_Identity=55.46875, Blast_Score=407, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17539378, Length=393, Percent_Identity=47.0737913486005, Blast_Score=343, Evalue=1e-94,
Organism=Caenorhabditis elegans, GI17567829, Length=391, Percent_Identity=45.7800511508951, Blast_Score=327, Evalue=6e-90,
Organism=Saccharomyces cerevisiae, GI6321683, Length=393, Percent_Identity=44.0203562340967, Blast_Score=330, Evalue=2e-91,
Organism=Drosophila melanogaster, GI161078106, Length=393, Percent_Identity=47.5826972010178, Blast_Score=336, Evalue=2e-92,
Organism=Drosophila melanogaster, GI24645208, Length=393, Percent_Identity=47.5826972010178, Blast_Score=336, Evalue=2e-92,
Organism=Drosophila melanogaster, GI281361397, Length=394, Percent_Identity=47.7157360406091, Blast_Score=335, Evalue=2e-92,
Organism=Drosophila melanogaster, GI281361395, Length=394, Percent_Identity=47.7157360406091, Blast_Score=335, Evalue=2e-92,
Organism=Drosophila melanogaster, GI21356231, Length=396, Percent_Identity=48.2323232323232, Blast_Score=324, Evalue=5e-89,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_ANAD2 (B8JAE0)

Other databases:

- EMBL:   CP001359
- RefSeq:   YP_002492725.1
- ProteinModelPortal:   B8JAE0
- SMR:   B8JAE0
- GeneID:   7297575
- GenomeReviews:   CP001359_GR
- KEGG:   acp:A2cp1_2321
- HOGENOM:   HBG315432
- ProtClustDB:   PRK00696
- HAMAP:   MF_00558
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 41123; Mature: 41123

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIHEYQAKEILRKFGVAVPRGYLAVTPLEAEGAARQLGGGISAVKAQIHAGGRGKGGGV
CCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHCCCHHHHHHEEECCCCCCCCCE
KLARSPDEARQHAEAMLGMMLKTPQTGPDGQEVRKVYVEEGCRIARELYLGMTLDREIGR
EEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEECCCCCC
LAVMASVEGGVDIEEVAAKHPDKILREWISPLTGLMPFQARRLAFGLGLTGDSVTAFVRF
EEEEEECCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHEECCCCCCHHHHHHHH
ATGLYNAYVATDASLAEINPLVITVGGEVLALDAKMNFDDNALYRHPDIAAMRDPDEEDP
HHHHHHHHHCCCCCHHHCCCEEEEECCEEEEEEEECCCCCCCEEECCCCCCCCCCCCCCC
KETQAKEYDLSYIALDGDIGCMVNGAGLAMATMDVIKLSGGQPANFLDVGGGADEDKVTA
HHHHHHHCCEEEEEECCCCEEEEECCCHHHHHEEHHEECCCCCCCEEECCCCCCCCHHEE
AFKIILSDPHVKAVLVNIFGGIMKCDVIANGIVAAAKQVGLSIPLVVRLEGTNVELGKDI
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHH
LAHSELKIIPADDLGDAARKVVQAARAA
HCCCCEEEEECCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKIHEYQAKEILRKFGVAVPRGYLAVTPLEAEGAARQLGGGISAVKAQIHAGGRGKGGGV
CCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHCCCHHHHHHEEECCCCCCCCCE
KLARSPDEARQHAEAMLGMMLKTPQTGPDGQEVRKVYVEEGCRIARELYLGMTLDREIGR
EEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEECCCCCC
LAVMASVEGGVDIEEVAAKHPDKILREWISPLTGLMPFQARRLAFGLGLTGDSVTAFVRF
EEEEEECCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHEECCCCCCHHHHHHHH
ATGLYNAYVATDASLAEINPLVITVGGEVLALDAKMNFDDNALYRHPDIAAMRDPDEEDP
HHHHHHHHHCCCCCHHHCCCEEEEECCEEEEEEEECCCCCCCEEECCCCCCCCCCCCCCC
KETQAKEYDLSYIALDGDIGCMVNGAGLAMATMDVIKLSGGQPANFLDVGGGADEDKVTA
HHHHHHHCCEEEEEECCCCEEEEECCCHHHHHEEHHEECCCCCCCEEECCCCCCCCHHEE
AFKIILSDPHVKAVLVNIFGGIMKCDVIANGIVAAAKQVGLSIPLVVRLEGTNVELGKDI
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHH
LAHSELKIIPADDLGDAARKVVQAARAA
HCCCCEEEEECCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA