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The map label for this gene is sucD [H]

Identifier: 220917420

GI number: 220917420

Start: 2571287

End: 2572312

Strand: Reverse

Name: sucD [H]

Synonym: A2cp1_2320

Alternate gene names: 220917420

Gene position: 2572312-2571287 (Counterclockwise)

Preceding gene: 220917421

Following gene: 220917419

Centisome position: 51.15

GC content: 73.39

Gene sequence:

>1026_bases
TTGAGCATCCTCGTAGATCGCAACACCCGGGTCCTCGTCCAGGGCATCACCGGCTCGGCGGGCAGCTTCCACGCCGAGCA
GATGCTCGCCTACGGCACGAACGTGGTGGCGGGCGTGACGCCCAACCGCGGCGGCACCCGCTTCCAGGGGACGGTGCCCA
TCTTCCACACGGTCGCGGCGGCGGTGAAGGAGACCGGCGCGAACGCGGCCGCGATCTTCGTGCCGCCCCCGTTCGCGGCC
GACGCGATCATCGAGGCGGCCGAGTCCGACATCGAGCTCATCGTGGCGATCACCGAGGGCATCCCGGTGCTCGACATGGT
CCGCGTGCGCCGCTACGTGGAGAGCCGCCCGAAGACGCGGCTGGTCGGGCCGAACTGCCCCGGCGTGATCACGCCCGGCC
AGTGCAAGATCGGGATCATGCCCGGGCACGTGCACCGGCCCGGCCGCATCGGCGTGGTCTCGCGCTCGGGCACGCTCAAC
TACGAGGCGGTGAAGCAGCTCAGCGACCTGGGCCTCGGCCAGTCCACCTCGGTGGGCATCGGCGGCGACCCGGTCCACGG
CACGGACTTCGTGCAGGCGCTGCAGCTGTTCGAGGACGACCCGGAGACCGACGCCGTCATCATGATCGGCGAGATCGGCG
GCGGCGAGGAGGAGAAGGGCGCCGAGTTCGTCCGCGACCACATGACGAAGCCGGTGGTCGGGTTCATCGCCGGCCGCACC
GCGCCCCCGGGCAAGCGCATGGGCCACGCCGGCGCGGTGATCTCGGGCGGCGCCGGCACCGCCGACGCGAAGATGGCGGC
CATGCGCGAGGCCGGCATCGTGGTGGTGGACGGTCCCCACCTGCTCGGCCGGGCGATGAAGGACGCGCTGTCGCGGCGCG
CCCGCCCCAAGCCCGCCAAGGCGCCGGCCGGCAAGCGGCCCGCGGCCGCCGCGCCCGGCAAGAAGGGCGCCGCCTCGCGC
AGCGCCGCACCCTCGCAGCGCGGCGGCAAGGCGCTGAAGAAGGCTGCCAAGGGGGAGCGCGACTAG

Upstream 100 bases:

>100_bases
CGCGGACGACCTCGGCGACGCTGCCCGGAAGGTCGTCCAGGCCGCGCGAGCCGCCTAGATCCAGGTCCATTCGTCGCACG
AGCGGCGGGAGGCACACGCC

Downstream 100 bases:

>100_bases
CGCGCCCCCGAGGATCCAGGGACGCTCGCGCCCCCGTGCTCACGGTGAGCCGGGGGCGCGGCTTTCCCGCAACCACCCGG
AACACCGGACGAACGGAGAG

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha; Vegetative protein 239; VEG239 [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MSILVDRNTRVLVQGITGSAGSFHAEQMLAYGTNVVAGVTPNRGGTRFQGTVPIFHTVAAAVKETGANAAAIFVPPPFAA
DAIIEAAESDIELIVAITEGIPVLDMVRVRRYVESRPKTRLVGPNCPGVITPGQCKIGIMPGHVHRPGRIGVVSRSGTLN
YEAVKQLSDLGLGQSTSVGIGGDPVHGTDFVQALQLFEDDPETDAVIMIGEIGGGEEEKGAEFVRDHMTKPVVGFIAGRT
APPGKRMGHAGAVISGGAGTADAKMAAMREAGIVVVDGPHLLGRAMKDALSRRARPKPAKAPAGKRPAAAAPGKKGAASR
SAAPSQRGGKALKKAAKGERD

Sequences:

>Translated_341_residues
MSILVDRNTRVLVQGITGSAGSFHAEQMLAYGTNVVAGVTPNRGGTRFQGTVPIFHTVAAAVKETGANAAAIFVPPPFAA
DAIIEAAESDIELIVAITEGIPVLDMVRVRRYVESRPKTRLVGPNCPGVITPGQCKIGIMPGHVHRPGRIGVVSRSGTLN
YEAVKQLSDLGLGQSTSVGIGGDPVHGTDFVQALQLFEDDPETDAVIMIGEIGGGEEEKGAEFVRDHMTKPVVGFIAGRT
APPGKRMGHAGAVISGGAGTADAKMAAMREAGIVVVDGPHLLGRAMKDALSRRARPKPAKAPAGKRPAAAAPGKKGAASR
SAAPSQRGGKALKKAAKGERD
>Mature_340_residues
SILVDRNTRVLVQGITGSAGSFHAEQMLAYGTNVVAGVTPNRGGTRFQGTVPIFHTVAAAVKETGANAAAIFVPPPFAAD
AIIEAAESDIELIVAITEGIPVLDMVRVRRYVESRPKTRLVGPNCPGVITPGQCKIGIMPGHVHRPGRIGVVSRSGTLNY
EAVKQLSDLGLGQSTSVGIGGDPVHGTDFVQALQLFEDDPETDAVIMIGEIGGGEEEKGAEFVRDHMTKPVVGFIAGRTA
PPGKRMGHAGAVISGGAGTADAKMAAMREAGIVVVDGPHLLGRAMKDALSRRARPKPAKAPAGKRPAAAAPGKKGAASRS
AAPSQRGGKALKKAAKGERD

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=295, Percent_Identity=56.6101694915254, Blast_Score=295, Evalue=5e-80,
Organism=Homo sapiens, GI38569421, Length=302, Percent_Identity=29.4701986754967, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI38569423, Length=302, Percent_Identity=29.4701986754967, Blast_Score=97, Evalue=3e-20,
Organism=Escherichia coli, GI1786949, Length=290, Percent_Identity=58.9655172413793, Blast_Score=365, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17550194, Length=293, Percent_Identity=55.2901023890785, Blast_Score=315, Evalue=2e-86,
Organism=Caenorhabditis elegans, GI17553126, Length=293, Percent_Identity=55.2901023890785, Blast_Score=311, Evalue=2e-85,
Organism=Caenorhabditis elegans, GI17557344, Length=270, Percent_Identity=28.1481481481481, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17551266, Length=241, Percent_Identity=29.8755186721992, Blast_Score=90, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324716, Length=299, Percent_Identity=47.1571906354515, Blast_Score=276, Evalue=4e-75,
Organism=Drosophila melanogaster, GI21356559, Length=312, Percent_Identity=52.5641025641026, Blast_Score=332, Evalue=2e-91,
Organism=Drosophila melanogaster, GI28574296, Length=295, Percent_Identity=54.5762711864407, Blast_Score=293, Evalue=8e-80,
Organism=Drosophila melanogaster, GI281363475, Length=275, Percent_Identity=29.8181818181818, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI281363473, Length=275, Percent_Identity=29.8181818181818, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI281363477, Length=275, Percent_Identity=29.8181818181818, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 35115; Mature: 34984

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILVDRNTRVLVQGITGSAGSFHAEQMLAYGTNVVAGVTPNRGGTRFQGTVPIFHTVAA
CEEEEECCCEEEEEECCCCCCCHHHHHHHHHCCCEEEECCCCCCCCEEECCCHHHHHHHH
AVKETGANAAAIFVPPPFAADAIIEAAESDIELIVAITEGIPVLDMVRVRRYVESRPKTR
HHHHCCCCEEEEEECCCCHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCEE
LVGPNCPGVITPGQCKIGIMPGHVHRPGRIGVVSRSGTLNYEAVKQLSDLGLGQSTSVGI
EECCCCCCEECCCCEEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCC
GGDPVHGTDFVQALQLFEDDPETDAVIMIGEIGGGEEEKGAEFVRDHMTKPVVGFIAGRT
CCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHCCC
APPGKRMGHAGAVISGGAGTADAKMAAMREAGIVVVDGPHLLGRAMKDALSRRARPKPAK
CCCCCCCCCCCCEEECCCCCCHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHCCCCCCCC
APAGKRPAAAAPGKKGAASRSAAPSQRGGKALKKAAKGERD
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SILVDRNTRVLVQGITGSAGSFHAEQMLAYGTNVVAGVTPNRGGTRFQGTVPIFHTVAA
EEEEECCCEEEEEECCCCCCCHHHHHHHHHCCCEEEECCCCCCCCEEECCCHHHHHHHH
AVKETGANAAAIFVPPPFAADAIIEAAESDIELIVAITEGIPVLDMVRVRRYVESRPKTR
HHHHCCCCEEEEEECCCCHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCEE
LVGPNCPGVITPGQCKIGIMPGHVHRPGRIGVVSRSGTLNYEAVKQLSDLGLGQSTSVGI
EECCCCCCEECCCCEEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCC
GGDPVHGTDFVQALQLFEDDPETDAVIMIGEIGGGEEEKGAEFVRDHMTKPVVGFIAGRT
CCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHCCC
APPGKRMGHAGAVISGGAGTADAKMAAMREAGIVVVDGPHLLGRAMKDALSRRARPKPAK
CCCCCCCCCCCCEEECCCCCCHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHCCCCCCCC
APAGKRPAAAAPGKKGAASRSAAPSQRGGKALKKAAKGERD
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]