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The map label for this gene is mrp [H]

Identifier: 220917372

GI number: 220917372

Start: 2522774

End: 2523859

Strand: Direct

Name: mrp [H]

Synonym: A2cp1_2272

Alternate gene names: 220917372

Gene position: 2522774-2523859 (Clockwise)

Preceding gene: 220917371

Following gene: 220917373

Centisome position: 50.16

GC content: 72.19

Gene sequence:

>1086_bases
ATGCCGCTCGACAACGCCGCCGCGCTCGAAGCCCTGAAGAAGGTCATGGACCCGGAGCTTCACCGGGACCTCGTCTCCCT
CGGGATGGTCAAGGATCTCTCGGTGGACGGCGACGCCGTGCGCCTGAAGGTGGAGCTCACCACCCCGGCCTGTCCGCTGA
AGGACACCATCGGACGCGACGTGGAGGGGGCGCTCCGGCGCGCCGGCTTCGCGCGGGTCGAGATCCACTGGGGCGCGCAG
GTCCGCTCCGCGCCCGGCGTGGCGCAGTCGTCGCTCACCCCCGGGGTGAAGAACATCATCCTGGTGGGCGCCGGGAAGGG
CGGCGTGGGCAAGAGCACCGTCGCCATCAACCTCGCGGTGGGCCTCGCCCGCCAGGGCGCCAAGGTCGGCATCCTCGACG
CCGACATCTACGGGCCCTCGGTGCCGATCCTCACCGGCCTCGACCAGAAGCCCACCTCGCGCGACGGGCAGAAGCTCGAT
CCGCTCGAGGCGCACGGCATCAAGGTCATGTCGATCGGCTTCCTCATCGACCCGGAGCAGGCGCTGATCTGGCGCGGCCC
GATGGTCACCGGCGCGCTGGTGCAGCTGCTGCGCGACGTGAACTGGGGCGAGCTGGACTACCTCGTGCTCGACCTGCCGC
CGGGCACCGGCGACGTCCCGCTCACGCTCGCCCAGAACGTGCGCGCGGCCGGCGTGGTGCTGGTCTCGACGCCGCAGGAC
GTGGCGCTCGCCGACGTGATCCGCGCCAAGCTCATGTTCGACAAGGTCTCCATCCCGGTGCTCGGCCTGGTGGAGAACAT
GTCCGCGTTCGTGTGCCCGCACTGCCGCCACGAGACGGCCATCTTCGACAAGGGCGGCGCGCAGGCCGCGGCGGAGAAGA
TGGGCGTCCGCTTCCTGGGCGCGGTGCCCATCGACCTCGCCATCCGCGAGGGCGGCGACAAGGGCGTCCCGGTGGTCGCG
GGCGCGCCCGACAGCCCGCAGGCCGAGGCGTTCCTGAGCGTGGCCCGCAACGTGGCCGGCGCGGTCAGCACGCAGGTGCT
GAAGGCGCCGCGCCTGCCGGTGATCGGCGCGCAGCCGCGCGCCTGA

Upstream 100 bases:

>100_bases
TGCTGGTCGCCGAGGGCGGGCGCTGGCGCGTGGACGCGCTGGAGTGAGCGGCGCCCCTTGAGATTGAGAAGCCGAGGGCA
GACCGCTATAAAGGCCGACC

Downstream 100 bases:

>100_bases
CCGAGGAGGGCGCCGTGGAGGGGCGGCCGTTCGAGGACGACGAGGTGCCGGCGGGCGAGCCGGACGACGCGCTCGACGCT
CCCGGGCTGGAGCCGGACGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MPLDNAAALEALKKVMDPELHRDLVSLGMVKDLSVDGDAVRLKVELTTPACPLKDTIGRDVEGALRRAGFARVEIHWGAQ
VRSAPGVAQSSLTPGVKNIILVGAGKGGVGKSTVAINLAVGLARQGAKVGILDADIYGPSVPILTGLDQKPTSRDGQKLD
PLEAHGIKVMSIGFLIDPEQALIWRGPMVTGALVQLLRDVNWGELDYLVLDLPPGTGDVPLTLAQNVRAAGVVLVSTPQD
VALADVIRAKLMFDKVSIPVLGLVENMSAFVCPHCRHETAIFDKGGAQAAAEKMGVRFLGAVPIDLAIREGGDKGVPVVA
GAPDSPQAEAFLSVARNVAGAVSTQVLKAPRLPVIGAQPRA

Sequences:

>Translated_361_residues
MPLDNAAALEALKKVMDPELHRDLVSLGMVKDLSVDGDAVRLKVELTTPACPLKDTIGRDVEGALRRAGFARVEIHWGAQ
VRSAPGVAQSSLTPGVKNIILVGAGKGGVGKSTVAINLAVGLARQGAKVGILDADIYGPSVPILTGLDQKPTSRDGQKLD
PLEAHGIKVMSIGFLIDPEQALIWRGPMVTGALVQLLRDVNWGELDYLVLDLPPGTGDVPLTLAQNVRAAGVVLVSTPQD
VALADVIRAKLMFDKVSIPVLGLVENMSAFVCPHCRHETAIFDKGGAQAAAEKMGVRFLGAVPIDLAIREGGDKGVPVVA
GAPDSPQAEAFLSVARNVAGAVSTQVLKAPRLPVIGAQPRA
>Mature_360_residues
PLDNAAALEALKKVMDPELHRDLVSLGMVKDLSVDGDAVRLKVELTTPACPLKDTIGRDVEGALRRAGFARVEIHWGAQV
RSAPGVAQSSLTPGVKNIILVGAGKGGVGKSTVAINLAVGLARQGAKVGILDADIYGPSVPILTGLDQKPTSRDGQKLDP
LEAHGIKVMSIGFLIDPEQALIWRGPMVTGALVQLLRDVNWGELDYLVLDLPPGTGDVPLTLAQNVRAAGVVLVSTPQDV
ALADVIRAKLMFDKVSIPVLGLVENMSAFVCPHCRHETAIFDKGGAQAAAEKMGVRFLGAVPIDLAIREGGDKGVPVVAG
APDSPQAEAFLSVARNVAGAVSTQVLKAPRLPVIGAQPRA

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI157384956, Length=246, Percent_Identity=49.5934959349593, Blast_Score=248, Evalue=9e-66,
Organism=Homo sapiens, GI118572611, Length=265, Percent_Identity=41.8867924528302, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI6912540, Length=255, Percent_Identity=41.5686274509804, Blast_Score=200, Evalue=2e-51,
Organism=Escherichia coli, GI87082045, Length=344, Percent_Identity=43.3139534883721, Blast_Score=272, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI25143050, Length=252, Percent_Identity=40.8730158730159, Blast_Score=181, Evalue=5e-46,
Organism=Saccharomyces cerevisiae, GI6322188, Length=229, Percent_Identity=44.1048034934498, Blast_Score=193, Evalue=4e-50,
Organism=Saccharomyces cerevisiae, GI6321347, Length=256, Percent_Identity=39.84375, Blast_Score=181, Evalue=1e-46,
Organism=Drosophila melanogaster, GI221511043, Length=275, Percent_Identity=38.9090909090909, Blast_Score=209, Evalue=3e-54,
Organism=Drosophila melanogaster, GI24667611, Length=250, Percent_Identity=42.8, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI19921440, Length=232, Percent_Identity=41.3793103448276, Blast_Score=151, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR015223
- InterPro:   IPR002744
- InterPro:   IPR000808 [H]

Pfam domain/function: PF01883 DUF59; PF09140 MipZ; PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 37627; Mature: 37496

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLDNAAALEALKKVMDPELHRDLVSLGMVKDLSVDGDAVRLKVELTTPACPLKDTIGRD
CCCCHHHHHHHHHHHHCHHHHHHHHHHCCCEECCCCCCEEEEEEEECCCCCCCHHHHCCC
VEGALRRAGFARVEIHWGAQVRSAPGVAQSSLTPGVKNIILVGAGKGGVGKSTVAINLAV
HHHHHHHCCCEEEEEEECCEECCCCCCCHHCCCCCCCEEEEEECCCCCCCCCEEEEEEEE
GLARQGAKVGILDADIYGPSVPILTGLDQKPTSRDGQKLDPLEAHGIKVMSIGFLIDPEQ
ECCCCCCEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCHHHCCEEEEEEEEEECCCC
ALIWRGPMVTGALVQLLRDVNWGELDYLVLDLPPGTGDVPLTLAQNVRAAGVVLVSTPQD
EEEEECCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHCCCCCCCEEEEECCCC
VALADVIRAKLMFDKVSIPVLGLVENMSAFVCPHCRHETAIFDKGGAQAAAEKMGVRFLG
HHHHHHHHHHHHHHHCCCCHHHHHHCCHHHCCCCCCCCCEEEECCCHHHHHHHCCEEEEE
AVPIDLAIREGGDKGVPVVAGAPDSPQAEAFLSVARNVAGAVSTQVLKAPRLPVIGAQPR
CCCEEEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
A
C
>Mature Secondary Structure 
PLDNAAALEALKKVMDPELHRDLVSLGMVKDLSVDGDAVRLKVELTTPACPLKDTIGRD
CCCHHHHHHHHHHHHCHHHHHHHHHHCCCEECCCCCCEEEEEEEECCCCCCCHHHHCCC
VEGALRRAGFARVEIHWGAQVRSAPGVAQSSLTPGVKNIILVGAGKGGVGKSTVAINLAV
HHHHHHHCCCEEEEEEECCEECCCCCCCHHCCCCCCCEEEEEECCCCCCCCCEEEEEEEE
GLARQGAKVGILDADIYGPSVPILTGLDQKPTSRDGQKLDPLEAHGIKVMSIGFLIDPEQ
ECCCCCCEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCHHHCCEEEEEEEEEECCCC
ALIWRGPMVTGALVQLLRDVNWGELDYLVLDLPPGTGDVPLTLAQNVRAAGVVLVSTPQD
EEEEECCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHCCCCCCCEEEEECCCC
VALADVIRAKLMFDKVSIPVLGLVENMSAFVCPHCRHETAIFDKGGAQAAAEKMGVRFLG
HHHHHHHHHHHHHHHCCCCHHHHHHCCHHHCCCCCCCCCEEEECCCHHHHHHHCCEEEEE
AVPIDLAIREGGDKGVPVVAGAPDSPQAEAFLSVARNVAGAVSTQVLKAPRLPVIGAQPR
CCCEEEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]