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The map label for this gene is aspB [H]

Identifier: 220917306

GI number: 220917306

Start: 2446520

End: 2447722

Strand: Direct

Name: aspB [H]

Synonym: A2cp1_2206

Alternate gene names: 220917306

Gene position: 2446520-2447722 (Clockwise)

Preceding gene: 220917305

Following gene: 220917307

Centisome position: 48.65

GC content: 68.41

Gene sequence:

>1203_bases
ATGAAGCTCGCGAAGCGGCTGGACGTGGTCAAGCCGTCGCCCACCCTGGCCATCACCGCGAAGGCGCGGGAGATGAAGTC
GAAGGGCATCGACGTGGTGGGGTTCGGCGCCGGCGAGCCGGACTTCGACACGCCGTCGATGATCAAGGACGCGGCGAAGA
AGGCGATCGACGCCGGCTTCACGAAGTACACGCCCACGAACGGCATCGTCGAGCTGCGCGAGGCGATCGCGGCCCGCATC
CAGCAGGAGCACCGGGTCTCGTACAAGGCGAGCGAGGTGCTGGTCTCCTGCGGCGGCAAGCACGCGCTCTACAACCTGTT
CCAGGCGCTGCTGAACGACGGGGACGAGGTCGTCATCTTCACGCCGTACTGGGTCTCCTACGCGGACATGGTGCGGGTGG
CGGGCGGCGTCCCGGTGCTGGTCGAGACCAGCATGGACACCGGCTTCGATCCCTCCCCGGAGCAGATCCGCAAGGCGATC
GGGCCGAAGACCCGGGCCGTGATCGTGAACAGCCCGTCCAACCCGACCGGCGCGATGCTCTCCCGCCGCACGCTCGAGAC
GGTGATCTCCTGCGTGAAGGGCACCGAGACGCTCATCGTCTCCGACGACATCTACGACAAGCTCGTCTACCGCGGGAAGT
TCGAGAACGTCCTCGACCTCGACCCGTCGCTGCAGGGCCAGGTGGCGCTGGTGAACGGCGCCTCCAAGACGTTCTCCATG
ACCGGGTGGCGCATCGGCTGGACCGCCGGCCCGCAGGCGCTCATCTCGGCCATGCAGAAGCTCCAGGACAACTCGACCTC
CAACCCCGCCTCGATCTCGCAGAAGGCGGCGCTCGGCGCGCTGACGGCCCCCGGGGTGGGCGACGAGGTCGAGAAGATGC
GCAGGACGTTCGACGAGCGGCGCAAGCACATCGTCGGCCGCCTGAACGCCATCGACGGCGTCCGCTGCTTCGACCCGGGC
GGCTCGTTCTACGCGTTCCCCTACGTCGGCGAGCTGCTGAAGCGGACCGCCCCCGGCGCGAGCGCGCCGCTCGGCACCGA
CGACAAGCTCATCGACCTGCTCCTCGAGAAGCACCTGGTGGCCGCGGTCCCGGGCTCCGCCTTCGGCGCGCCCGGCTACA
TGCGCCTGTCGTTCGCGACCTCCATGGAGCAGATCGACAAGGGCTGCGACCGCATCGCGGAGATGGCGAAGAGCCTGAAG
TAG

Upstream 100 bases:

>100_bases
CGCCCCTGGCGGCGAGCACCCGTTCTGGTATTCTCGGTTCCCTTTTTTTCACGCCGCGGAGGCACGGCGGCGGTCACCTT
CTCTCCGAGGGAACGGAACC

Downstream 100 bases:

>100_bases
CTCCGGACACACAACGGGCGCCCCGCCGGCCTCCGGGCCGTGCGGGGCGTCGCGCTTTCGGGGGGGGATGGCAGGAATCC
GGACCCGCCGAACGAGGGGG

Product: class I and II aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MKLAKRLDVVKPSPTLAITAKAREMKSKGIDVVGFGAGEPDFDTPSMIKDAAKKAIDAGFTKYTPTNGIVELREAIAARI
QQEHRVSYKASEVLVSCGGKHALYNLFQALLNDGDEVVIFTPYWVSYADMVRVAGGVPVLVETSMDTGFDPSPEQIRKAI
GPKTRAVIVNSPSNPTGAMLSRRTLETVISCVKGTETLIVSDDIYDKLVYRGKFENVLDLDPSLQGQVALVNGASKTFSM
TGWRIGWTAGPQALISAMQKLQDNSTSNPASISQKAALGALTAPGVGDEVEKMRRTFDERRKHIVGRLNAIDGVRCFDPG
GSFYAFPYVGELLKRTAPGASAPLGTDDKLIDLLLEKHLVAAVPGSAFGAPGYMRLSFATSMEQIDKGCDRIAEMAKSLK

Sequences:

>Translated_400_residues
MKLAKRLDVVKPSPTLAITAKAREMKSKGIDVVGFGAGEPDFDTPSMIKDAAKKAIDAGFTKYTPTNGIVELREAIAARI
QQEHRVSYKASEVLVSCGGKHALYNLFQALLNDGDEVVIFTPYWVSYADMVRVAGGVPVLVETSMDTGFDPSPEQIRKAI
GPKTRAVIVNSPSNPTGAMLSRRTLETVISCVKGTETLIVSDDIYDKLVYRGKFENVLDLDPSLQGQVALVNGASKTFSM
TGWRIGWTAGPQALISAMQKLQDNSTSNPASISQKAALGALTAPGVGDEVEKMRRTFDERRKHIVGRLNAIDGVRCFDPG
GSFYAFPYVGELLKRTAPGASAPLGTDDKLIDLLLEKHLVAAVPGSAFGAPGYMRLSFATSMEQIDKGCDRIAEMAKSLK
>Mature_400_residues
MKLAKRLDVVKPSPTLAITAKAREMKSKGIDVVGFGAGEPDFDTPSMIKDAAKKAIDAGFTKYTPTNGIVELREAIAARI
QQEHRVSYKASEVLVSCGGKHALYNLFQALLNDGDEVVIFTPYWVSYADMVRVAGGVPVLVETSMDTGFDPSPEQIRKAI
GPKTRAVIVNSPSNPTGAMLSRRTLETVISCVKGTETLIVSDDIYDKLVYRGKFENVLDLDPSLQGQVALVNGASKTFSM
TGWRIGWTAGPQALISAMQKLQDNSTSNPASISQKAALGALTAPGVGDEVEKMRRTFDERRKHIVGRLNAIDGVRCFDPG
GSFYAFPYVGELLKRTAPGASAPLGTDDKLIDLLLEKHLVAAVPGSAFGAPGYMRLSFATSMEQIDKGCDRIAEMAKSLK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=367, Percent_Identity=28.0653950953678, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI56713256, Length=367, Percent_Identity=28.0653950953678, Blast_Score=155, Evalue=8e-38,
Organism=Homo sapiens, GI95147551, Length=388, Percent_Identity=27.0618556701031, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI169881279, Length=388, Percent_Identity=27.0618556701031, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI169881281, Length=384, Percent_Identity=22.3958333333333, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI4507369, Length=402, Percent_Identity=22.636815920398, Blast_Score=98, Evalue=2e-20,
Organism=Escherichia coli, GI1786816, Length=371, Percent_Identity=25.3369272237197, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788627, Length=368, Percent_Identity=26.6304347826087, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1788722, Length=401, Percent_Identity=26.6832917705736, Blast_Score=105, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17567369, Length=243, Percent_Identity=28.3950617283951, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71994476, Length=255, Percent_Identity=28.6274509803922, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71994472, Length=255, Percent_Identity=28.6274509803922, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17567663, Length=351, Percent_Identity=27.0655270655271, Blast_Score=115, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6322401, Length=368, Percent_Identity=27.9891304347826, Blast_Score=134, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6323118, Length=381, Percent_Identity=23.8845144356955, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320317, Length=363, Percent_Identity=23.6914600550964, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI28573069, Length=437, Percent_Identity=26.0869565217391, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24646114, Length=437, Percent_Identity=26.0869565217391, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI28573067, Length=437, Percent_Identity=26.0869565217391, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI28573065, Length=437, Percent_Identity=26.0869565217391, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI18859735, Length=366, Percent_Identity=23.224043715847, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43049; Mature: 43049

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLAKRLDVVKPSPTLAITAKAREMKSKGIDVVGFGAGEPDFDTPSMIKDAAKKAIDAGF
CCHHHHCCCCCCCCCEEEEEHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCC
TKYTPTNGIVELREAIAARIQQEHRVSYKASEVLVSCGGKHALYNLFQALLNDGDEVVIF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEE
TPYWVSYADMVRVAGGVPVLVETSMDTGFDPSPEQIRKAIGPKTRAVIVNSPSNPTGAML
CCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCHHHHH
SRRTLETVISCVKGTETLIVSDDIYDKLVYRGKFENVLDLDPSLQGQVALVNGASKTFSM
HHHHHHHHHHHHCCCCEEEEECHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCEEEE
TGWRIGWTAGPQALISAMQKLQDNSTSNPASISQKAALGALTAPGVGDEVEKMRRTFDER
CCEEEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
RKHIVGRLNAIDGVRCFDPGGSFYAFPYVGELLKRTAPGASAPLGTDDKLIDLLLEKHLV
HHHHHHHHHCCCCEEEECCCCCEEEHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
AAVPGSAFGAPGYMRLSFATSMEQIDKGCDRIAEMAKSLK
HCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLAKRLDVVKPSPTLAITAKAREMKSKGIDVVGFGAGEPDFDTPSMIKDAAKKAIDAGF
CCHHHHCCCCCCCCCEEEEEHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCC
TKYTPTNGIVELREAIAARIQQEHRVSYKASEVLVSCGGKHALYNLFQALLNDGDEVVIF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEE
TPYWVSYADMVRVAGGVPVLVETSMDTGFDPSPEQIRKAIGPKTRAVIVNSPSNPTGAML
CCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCHHHHH
SRRTLETVISCVKGTETLIVSDDIYDKLVYRGKFENVLDLDPSLQGQVALVNGASKTFSM
HHHHHHHHHHHHCCCCEEEEECHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCEEEE
TGWRIGWTAGPQALISAMQKLQDNSTSNPASISQKAALGALTAPGVGDEVEKMRRTFDER
CCEEEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
RKHIVGRLNAIDGVRCFDPGGSFYAFPYVGELLKRTAPGASAPLGTDDKLIDLLLEKHLV
HHHHHHHHHCCCCEEEECCCCCEEEHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
AAVPGSAFGAPGYMRLSFATSMEQIDKGCDRIAEMAKSLK
HCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]