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The map label for this gene is atoS [C]

Identifier: 220917276

GI number: 220917276

Start: 2415753

End: 2417552

Strand: Direct

Name: atoS [C]

Synonym: A2cp1_2175

Alternate gene names: 220917276

Gene position: 2415753-2417552 (Clockwise)

Preceding gene: 220917275

Following gene: 220917277

Centisome position: 48.03

GC content: 74.22

Gene sequence:

>1800_bases
ATGCACCACGCCGACGCCGACTCCCCCGGGCGCCGCGCCGCCTCCGGCCAGCACCTGCTCCGCCTCGCGGTCGCGCTGGG
CTGCGCGCTCGCGCTCGCCCTCGCCCTGCCAACGGTGGCCGACGACCGCGCCGCGCCGGGAGCCCGCGCGCCGGCGCGGC
AGCGGGTGATCGTCGGCGGCGACCAGAGCTACCCGCCCTACGAGTTCCTGGATCAGCAGGGCAGGCCCGCGGGGTTCAAC
GTGGATCTCACCCGCGCCGTGGCGCGCACCGTCGGGCTCGAGGTCGAGTTCCGCCTGGGCCGCTGGGCCGACATGCGGCG
CGCGCTCGAGACCGGCGAGATCGACGCACTGCAGGGCATGTCCTTCTCGGAGCAGCGCGCCAAGGAGGTCGACTTCACGC
CGCCGAGCCTGATCGTCCACCACGCCATCTTCGCGCGGCGCGGCGACCGGCCGGTCCGATCGCTCGCCGACCTCGCCGGC
AAGGAGGTGCTGGTGCTGCGCAGCGGCATCATGCACGACACCCTCCGGCGCGAGCACCCCGACGTGAAGGTCGTCCCGGC
CGACACGCACGCAGACGTGCTGCGGCAGCTCGCGGCGGGCAAGCACGACTACGCGGTGATGGCGAAGCTGCCGGGCCTGT
ACCTGGTCCGCGAGATGGGCCTGTCCAACCTGACCGCGATGGACCAGCCGGCGGCGGTGGAGCGCTACGGCTACGCGGTC
CGCCGGGGCAACGAGGCGCTCGCGGCGCGGCTCGCCGAGGGGCTCGCGATCGTGCGCAACACCGGCGAGTACCAGTCCAT
GTCCGAGGCGTGGCTGGGCGTGCTCGAGCCGCGCGGCCCGACGGTGCAGCAGGTGCTGCGCTGGGGCGCGTTCGTGCTCG
TCCCGCTCGTGCTCCTGCTCGCCACCATGGCGGCGTGGTCCCGCACGCTGCACCGGCAGGTGACGCTCAGGACCGCGGAC
CTCACCCGCGAGATCGCCGAGCGCCGGCAGAAGGAGGAGGAGCTGCGCTCGAACCAGCAGCAGCTCCTGCAGGCCGACAA
GATGGCGGCGCTCGGGGTGCTGGTGTCCGGCGTGGCGCACGAGATCAACAACCCGAACGGCCTCATCCTGCTCGACCTGC
AGGTCCTCGACGACGTGCTGCGCGACGCGACGCCCATCCTGGACGCCCACGCGCGCGCGAACGGGGACTACACGCTCGGC
AGCCTGCGCTGGTCGCGGCTCCGCGAGGCCATGCCGAGCATGGTGTCGGACGCGCTCGACGCCTCCCGCCGCGTGAAGCG
GATCGTGGAGGACCTGAAGGACTTCGCCCGGCAGGAGTCGCCCGAGCTGCGCGACGGGGTCTCCGTCGACGAGGTGGCGC
GGACCGCCGCGCGGCTGGTGGAGGCGCTCGTCAAGAAGAGCACCGAGCGGTTCGAGGTGGCGCTGGAGCGCGGGCTGCCG
CCGGTCCGCGGCAACCCGCAGCGGCTGGAGCAGGTCCTCGTGAACCTGCTCGTGAACGCCTGCCAGGCGCTCCCGGGCCG
CTCGCACGGGATCCGCCTGCGGACGTTCCTCGACGCGGGGCGGGGCGCGGTGTGCGTCGAGGTCCGTGACGAGGGGGTGG
GGATCGAGGCGCAGCACCTGCCCCGCCTCACCGACCCGTTCTTCACCACCAAGCGCGACCGCGGCGGCACCGGGCTCGGC
CTGGCGGTCTCCGCGGGCATCGTGAAGGAGCACGGCGGCACGCTCGAGTTCGAGTCGGCGCCGGGGCAGGGCACCGCGGC
GCGAGTGGTCCTGCCCGTCGCCCGCGAGGAGGCCGCGTGA

Upstream 100 bases:

>100_bases
GCGGCGCTGCGCCGCGGCGATCCTTGTGGCCGCGGGGGGCCGGCCGTACCATGCTGACCCTGCCGCGGCGGCCCGCACCG
AGGGCCGCCGGGCAGCACGC

Downstream 100 bases:

>100_bases
GCGAGATCGCGTACCCGCCGTTCGCCGTGCTGCTCGTGGACGACGAGCCGGGCTGGCTGCGGACCATGTCGCTCAGCCTG
GAGCGCTCGCTGGGCGTCAC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 599; Mature: 599

Protein sequence:

>599_residues
MHHADADSPGRRAASGQHLLRLAVALGCALALALALPTVADDRAAPGARAPARQRVIVGGDQSYPPYEFLDQQGRPAGFN
VDLTRAVARTVGLEVEFRLGRWADMRRALETGEIDALQGMSFSEQRAKEVDFTPPSLIVHHAIFARRGDRPVRSLADLAG
KEVLVLRSGIMHDTLRREHPDVKVVPADTHADVLRQLAAGKHDYAVMAKLPGLYLVREMGLSNLTAMDQPAAVERYGYAV
RRGNEALAARLAEGLAIVRNTGEYQSMSEAWLGVLEPRGPTVQQVLRWGAFVLVPLVLLLATMAAWSRTLHRQVTLRTAD
LTREIAERRQKEEELRSNQQQLLQADKMAALGVLVSGVAHEINNPNGLILLDLQVLDDVLRDATPILDAHARANGDYTLG
SLRWSRLREAMPSMVSDALDASRRVKRIVEDLKDFARQESPELRDGVSVDEVARTAARLVEALVKKSTERFEVALERGLP
PVRGNPQRLEQVLVNLLVNACQALPGRSHGIRLRTFLDAGRGAVCVEVRDEGVGIEAQHLPRLTDPFFTTKRDRGGTGLG
LAVSAGIVKEHGGTLEFESAPGQGTAARVVLPVAREEAA

Sequences:

>Translated_599_residues
MHHADADSPGRRAASGQHLLRLAVALGCALALALALPTVADDRAAPGARAPARQRVIVGGDQSYPPYEFLDQQGRPAGFN
VDLTRAVARTVGLEVEFRLGRWADMRRALETGEIDALQGMSFSEQRAKEVDFTPPSLIVHHAIFARRGDRPVRSLADLAG
KEVLVLRSGIMHDTLRREHPDVKVVPADTHADVLRQLAAGKHDYAVMAKLPGLYLVREMGLSNLTAMDQPAAVERYGYAV
RRGNEALAARLAEGLAIVRNTGEYQSMSEAWLGVLEPRGPTVQQVLRWGAFVLVPLVLLLATMAAWSRTLHRQVTLRTAD
LTREIAERRQKEEELRSNQQQLLQADKMAALGVLVSGVAHEINNPNGLILLDLQVLDDVLRDATPILDAHARANGDYTLG
SLRWSRLREAMPSMVSDALDASRRVKRIVEDLKDFARQESPELRDGVSVDEVARTAARLVEALVKKSTERFEVALERGLP
PVRGNPQRLEQVLVNLLVNACQALPGRSHGIRLRTFLDAGRGAVCVEVRDEGVGIEAQHLPRLTDPFFTTKRDRGGTGLG
LAVSAGIVKEHGGTLEFESAPGQGTAARVVLPVAREEAA
>Mature_599_residues
MHHADADSPGRRAASGQHLLRLAVALGCALALALALPTVADDRAAPGARAPARQRVIVGGDQSYPPYEFLDQQGRPAGFN
VDLTRAVARTVGLEVEFRLGRWADMRRALETGEIDALQGMSFSEQRAKEVDFTPPSLIVHHAIFARRGDRPVRSLADLAG
KEVLVLRSGIMHDTLRREHPDVKVVPADTHADVLRQLAAGKHDYAVMAKLPGLYLVREMGLSNLTAMDQPAAVERYGYAV
RRGNEALAARLAEGLAIVRNTGEYQSMSEAWLGVLEPRGPTVQQVLRWGAFVLVPLVLLLATMAAWSRTLHRQVTLRTAD
LTREIAERRQKEEELRSNQQQLLQADKMAALGVLVSGVAHEINNPNGLILLDLQVLDDVLRDATPILDAHARANGDYTLG
SLRWSRLREAMPSMVSDALDASRRVKRIVEDLKDFARQESPELRDGVSVDEVARTAARLVEALVKKSTERFEVALERGLP
PVRGNPQRLEQVLVNLLVNACQALPGRSHGIRLRTFLDAGRGAVCVEVRDEGVGIEAQHLPRLTDPFFTTKRDRGGTGLG
LAVSAGIVKEHGGTLEFESAPGQGTAARVVLPVAREEAA

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc; May Activate Atoc By Phosphorylation. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=258, Percent_Identity=29.4573643410853, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1790436, Length=255, Percent_Identity=31.7647058823529, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1788228, Length=260, Percent_Identity=26.1538461538462, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1787085, Length=229, Percent_Identity=26.2008733624454, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1787031, Length=267, Percent_Identity=25.8426966292135, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI145693157, Length=279, Percent_Identity=25.8064516129032, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1787088, Length=235, Percent_Identity=25.9574468085106, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790300, Length=270, Percent_Identity=30.3703703703704, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI87081816, Length=292, Percent_Identity=28.7671232876712, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786600, Length=180, Percent_Identity=31.6666666666667, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1789149, Length=168, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 65364; Mature: 65364

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHHADADSPGRRAASGQHLLRLAVALGCALALALALPTVADDRAAPGARAPARQRVIVGG
CCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECC
DQSYPPYEFLDQQGRPAGFNVDLTRAVARTVGLEVEFRLGRWADMRRALETGEIDALQGM
CCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHCCEEEEECCCHHHHHHHHHCCCCHHHCCC
SFSEQRAKEVDFTPPSLIVHHAIFARRGDRPVRSLADLAGKEVLVLRSGIMHDTLRREHP
CCHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHCCC
DVKVVPADTHADVLRQLAAGKHDYAVMAKLPGLYLVREMGLSNLTAMDQPAAVERYGYAV
CEEEEECCCHHHHHHHHHCCCCCEEHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
RRGNEALAARLAEGLAIVRNTGEYQSMSEAWLGVLEPRGPTVQQVLRWGAFVLVPLVLLL
HCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
ATMAAWSRTLHRQVTLRTADLTREIAERRQKEEELRSNQQQLLQADKMAALGVLVSGVAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EINNPNGLILLDLQVLDDVLRDATPILDAHARANGDYTLGSLRWSRLREAMPSMVSDALD
HCCCCCCEEEEEHHHHHHHHHCCCHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHH
ASRRVKRIVEDLKDFARQESPELRDGVSVDEVARTAARLVEALVKKSTERFEVALERGLP
HHHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
PVRGNPQRLEQVLVNLLVNACQALPGRSHGIRLRTFLDAGRGAVCVEVRDEGVGIEAQHL
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCHHHC
PRLTDPFFTTKRDRGGTGLGLAVSAGIVKEHGGTLEFESAPGQGTAARVVLPVAREEAA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEECHHCCCC
>Mature Secondary Structure
MHHADADSPGRRAASGQHLLRLAVALGCALALALALPTVADDRAAPGARAPARQRVIVGG
CCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECC
DQSYPPYEFLDQQGRPAGFNVDLTRAVARTVGLEVEFRLGRWADMRRALETGEIDALQGM
CCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHCCEEEEECCCHHHHHHHHHCCCCHHHCCC
SFSEQRAKEVDFTPPSLIVHHAIFARRGDRPVRSLADLAGKEVLVLRSGIMHDTLRREHP
CCHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHCCC
DVKVVPADTHADVLRQLAAGKHDYAVMAKLPGLYLVREMGLSNLTAMDQPAAVERYGYAV
CEEEEECCCHHHHHHHHHCCCCCEEHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
RRGNEALAARLAEGLAIVRNTGEYQSMSEAWLGVLEPRGPTVQQVLRWGAFVLVPLVLLL
HCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
ATMAAWSRTLHRQVTLRTADLTREIAERRQKEEELRSNQQQLLQADKMAALGVLVSGVAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EINNPNGLILLDLQVLDDVLRDATPILDAHARANGDYTLGSLRWSRLREAMPSMVSDALD
HCCCCCCEEEEEHHHHHHHHHCCCHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHH
ASRRVKRIVEDLKDFARQESPELRDGVSVDEVARTAARLVEALVKKSTERFEVALERGLP
HHHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
PVRGNPQRLEQVLVNLLVNACQALPGRSHGIRLRTFLDAGRGAVCVEVRDEGVGIEAQHL
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCHHHC
PRLTDPFFTTKRDRGGTGLGLAVSAGIVKEHGGTLEFESAPGQGTAARVVLPVAREEAA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEECHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1333793 [H]