Click here to switch to the map view.

The map label for this gene is nreB [H]

Identifier: 220917272

GI number: 220917272

Start: 2411623

End: 2413407

Strand: Direct

Name: nreB [H]

Synonym: A2cp1_2171

Alternate gene names: 220917272

Gene position: 2411623-2413407 (Clockwise)

Preceding gene: 220917271

Following gene: 220917273

Centisome position: 47.95

GC content: 77.82

Gene sequence:

>1785_bases
ATGCGCAGGCTCCTCGCCGTCCTCGGGACGCTCCGCGGCAGGCTGGTGCTGCTGGTCTGCTTCGCGACGCTGCCCGCGAT
GCTGTTCACGTTCTACGCGGCGAGCGCGGAGCGCACCGCGGTGCTGCGGCGCATCGAGCAGGAGGCGCTCCTGCTCGCGC
AGCTCGCCTCGCGCGAGCACGGCCACCAGCTCGAGGGCGCGCGCACGCTGCTGCGCCGGCTCGCCGGGCTGCTCCGGGCC
GCGCCGGAGGCAGGGGACGCGGCGCGCTGCCCGGAGCTGCTCCCGGCGCTGCTCGCCGGCTACCCGCAGTTCACCACCAT
CGGGATCCTCTCGCCGGAGGGCCGGCTCCGCTGCAGCGCCCGGCCCGCGCCGCCCGGGGTGACCTTCGCCGGCAGCGCGG
CGCTCGAGCGCGCGCTCTGGTCCAACGACGTCGAGGTGGGCGAGTACGCCCTCGGCCCGGTGGTGGGGCGCCCGGTGCTC
CACCTCGCCTACGCGGTGCGCGGCGCCGGCGGCGCGCCGTCGGAGGTGCTGTTCGTCGGCCTCGACCTGCAGTGGCTGGA
GCAGCTCGCGCACCAGGCCGAGCTGCCGGCGGGCTACGCGCTCGTGATCGCCGACCGGAACGGCGCCGCGCTCGGCCGCT
CCGGCGGCGACGCCTGGCCGGCCAGGGCGGCCCGCGACCCCGCGCTGGCGCGGGCGGTCGCGTCGCCGGGGCAGGGCACC
GTGACGGAGGCGCCCGCGGCGGACCGCCGGTTCCTGGTGGCGGCCCCGGTGGCGGCGGTGCCGGGCGTCTCGGTGGTGGC
GAGCCTGCCGTACACCCGGGTCGCCGCGCAGGCGAACCGCGCGTTCTACCGGACGGTCGCGGGGCTGGCGCTGCTCACGC
TGTTCACGATCGGCTGCGTGCTGCTCGCGGCCGAGGTGTCGGTGCTGCGCGTGCTCCGGCACCTGGCCCGCACCGCCCGT
CGCTTCGGCGAGGGGGAGCTCTCGGCCCGCGCCGAGACGCCGGCCGCCCACGGCGAGCTCGCCGAGCTGACGCGGGCGTT
CAACGCCATGGCGGACGCGCTCGCCGCGCGCCAGCGCGAGGCGGCCGAGAGCCAGGGGCGGCTCCGCGCCATGTCGCACC
GCCTGGCCGCCGCGCGCGAGGCCGAGGCGGCCGCGATCGCACGCGACCTGCACGACGAGCTGGGCCAGGTGCTCACCAGC
GTGAAGGTGGAGCTCGCGGCGCTGCAGCGGGCGGGCGCGGAGGGCGAGGACCCGGCGGCGCGGCGCGCGCGCGTCGCCGA
GCTCGGGCAGCGGCTCGACGAGGCGGTGGCGTTCGTGCGGCGGGTCTCCTCCGACCTCCGCCCGCCCGTGCTCGACCGGC
TCGGCCTCGCCGCCGCGCTCGAGGGGCTGGTGCGCGACCTCGAGCAGCGCACGCGGCTCGCGGTGATGCTGGACGTGGAC
CCCTCGGTCGAGCCGGTCGAGTGGCTCCCGGCCGTCACGCTGTTCCGGATCGTGCGCGAGGCGCTCACCAACGTGGTGCG
CCACGCCGGCGCGACCGAGGTCTGGATCGAGCTGCGCGCCACGCCGGGGGCCCTGGTCCTGACCGTGCGGGACGACGGCA
AGGGCATCGGTCCCTGGGCGGCGGACGACCGGCGCTCGCTCGGGATCCAGGGCATGCAGGAGCGCGCCCTGCTCGTGGAC
GGCACGTTCGAGATCTCCGGGACGCCGGGCGGCGGGACGACCGTCGTGGTAACGATCCCTCGGACGAGGACGGGCGCGAC
CGATGCTGCGCATCCTGCTGGCTGA

Upstream 100 bases:

>100_bases
TCGCGGGTGCAGGCTGCCCCGTAGGCGCGACGGTCGCGCCCCGTCCTGGCTGCCGGCGGCGTCCGCGGGGACGCCGCCGG
CGCGCTAGGGTGATCGCTGC

Downstream 100 bases:

>100_bases
CGATCACGCGATGTTCCGGTCCGGGCTCCGGCGCATCCTCGAGGCCGAGTTCCCGGGCGCGTCGGTGGGCGAGGCGGCCA
CCATCGGCGAGCTCGAGGCG

Product: histidine kinase

Products: NA

Alternate protein names: Nitrogen regulation protein B [H]

Number of amino acids: Translated: 594; Mature: 594

Protein sequence:

>594_residues
MRRLLAVLGTLRGRLVLLVCFATLPAMLFTFYAASAERTAVLRRIEQEALLLAQLASREHGHQLEGARTLLRRLAGLLRA
APEAGDAARCPELLPALLAGYPQFTTIGILSPEGRLRCSARPAPPGVTFAGSAALERALWSNDVEVGEYALGPVVGRPVL
HLAYAVRGAGGAPSEVLFVGLDLQWLEQLAHQAELPAGYALVIADRNGAALGRSGGDAWPARAARDPALARAVASPGQGT
VTEAPAADRRFLVAAPVAAVPGVSVVASLPYTRVAAQANRAFYRTVAGLALLTLFTIGCVLLAAEVSVLRVLRHLARTAR
RFGEGELSARAETPAAHGELAELTRAFNAMADALAARQREAAESQGRLRAMSHRLAAAREAEAAAIARDLHDELGQVLTS
VKVELAALQRAGAEGEDPAARRARVAELGQRLDEAVAFVRRVSSDLRPPVLDRLGLAAALEGLVRDLEQRTRLAVMLDVD
PSVEPVEWLPAVTLFRIVREALTNVVRHAGATEVWIELRATPGALVLTVRDDGKGIGPWAADDRRSLGIQGMQERALLVD
GTFEISGTPGGGTTVVVTIPRTRTGATDAAHPAG

Sequences:

>Translated_594_residues
MRRLLAVLGTLRGRLVLLVCFATLPAMLFTFYAASAERTAVLRRIEQEALLLAQLASREHGHQLEGARTLLRRLAGLLRA
APEAGDAARCPELLPALLAGYPQFTTIGILSPEGRLRCSARPAPPGVTFAGSAALERALWSNDVEVGEYALGPVVGRPVL
HLAYAVRGAGGAPSEVLFVGLDLQWLEQLAHQAELPAGYALVIADRNGAALGRSGGDAWPARAARDPALARAVASPGQGT
VTEAPAADRRFLVAAPVAAVPGVSVVASLPYTRVAAQANRAFYRTVAGLALLTLFTIGCVLLAAEVSVLRVLRHLARTAR
RFGEGELSARAETPAAHGELAELTRAFNAMADALAARQREAAESQGRLRAMSHRLAAAREAEAAAIARDLHDELGQVLTS
VKVELAALQRAGAEGEDPAARRARVAELGQRLDEAVAFVRRVSSDLRPPVLDRLGLAAALEGLVRDLEQRTRLAVMLDVD
PSVEPVEWLPAVTLFRIVREALTNVVRHAGATEVWIELRATPGALVLTVRDDGKGIGPWAADDRRSLGIQGMQERALLVD
GTFEISGTPGGGTTVVVTIPRTRTGATDAAHPAG
>Mature_594_residues
MRRLLAVLGTLRGRLVLLVCFATLPAMLFTFYAASAERTAVLRRIEQEALLLAQLASREHGHQLEGARTLLRRLAGLLRA
APEAGDAARCPELLPALLAGYPQFTTIGILSPEGRLRCSARPAPPGVTFAGSAALERALWSNDVEVGEYALGPVVGRPVL
HLAYAVRGAGGAPSEVLFVGLDLQWLEQLAHQAELPAGYALVIADRNGAALGRSGGDAWPARAARDPALARAVASPGQGT
VTEAPAADRRFLVAAPVAAVPGVSVVASLPYTRVAAQANRAFYRTVAGLALLTLFTIGCVLLAAEVSVLRVLRHLARTAR
RFGEGELSARAETPAAHGELAELTRAFNAMADALAARQREAAESQGRLRAMSHRLAAAREAEAAAIARDLHDELGQVLTS
VKVELAALQRAGAEGEDPAARRARVAELGQRLDEAVAFVRRVSSDLRPPVLDRLGLAAALEGLVRDLEQRTRLAVMLDVD
PSVEPVEWLPAVTLFRIVREALTNVVRHAGATEVWIELRATPGALVLTVRDDGKGIGPWAADDRRSLGIQGMQERALLVD
GTFEISGTPGGGTTVVVTIPRTRTGATDAAHPAG

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxyg

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788812, Length=200, Percent_Identity=33, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87082311, Length=227, Percent_Identity=29.5154185022026, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1787474, Length=214, Percent_Identity=31.7757009345794, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR017203 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 62770; Mature: 62770

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLLAVLGTLRGRLVLLVCFATLPAMLFTFYAASAERTAVLRRIEQEALLLAQLASREH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
GHQLEGARTLLRRLAGLLRAAPEAGDAARCPELLPALLAGYPQFTTIGILSPEGRLRCSA
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCEEECC
RPAPPGVTFAGSAALERALWSNDVEVGEYALGPVVGRPVLHLAYAVRGAGGAPSEVLFVG
CCCCCCCEECCHHHHHHHHHCCCCCCCHHHHCHHHHHHHHHHHHHHHCCCCCCCCEEEEE
LDLQWLEQLAHQAELPAGYALVIADRNGAALGRSGGDAWPARAARDPALARAVASPGQGT
CCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCC
VTEAPAADRRFLVAAPVAAVPGVSVVASLPYTRVAAQANRAFYRTVAGLALLTLFTIGCV
CCCCCCCCCEEEEECCHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAAEVSVLRVLRHLARTARRFGEGELSARAETPAAHGELAELTRAFNAMADALAARQRE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AAESQGRLRAMSHRLAAAREAEAAAIARDLHDELGQVLTSVKVELAALQRAGAEGEDPAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
RRARVAELGQRLDEAVAFVRRVSSDLRPPVLDRLGLAAALEGLVRDLEQRTRLAVMLDVD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECC
PSVEPVEWLPAVTLFRIVREALTNVVRHAGATEVWIELRATPGALVLTVRDDGKGIGPWA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCCCCCCC
ADDRRSLGIQGMQERALLVDGTFEISGTPGGGTTVVVTIPRTRTGATDAAHPAG
CCCCHHCCCCCCCCCEEEEECEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MRRLLAVLGTLRGRLVLLVCFATLPAMLFTFYAASAERTAVLRRIEQEALLLAQLASREH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
GHQLEGARTLLRRLAGLLRAAPEAGDAARCPELLPALLAGYPQFTTIGILSPEGRLRCSA
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCEEECC
RPAPPGVTFAGSAALERALWSNDVEVGEYALGPVVGRPVLHLAYAVRGAGGAPSEVLFVG
CCCCCCCEECCHHHHHHHHHCCCCCCCHHHHCHHHHHHHHHHHHHHHCCCCCCCCEEEEE
LDLQWLEQLAHQAELPAGYALVIADRNGAALGRSGGDAWPARAARDPALARAVASPGQGT
CCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCC
VTEAPAADRRFLVAAPVAAVPGVSVVASLPYTRVAAQANRAFYRTVAGLALLTLFTIGCV
CCCCCCCCCEEEEECCHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAAEVSVLRVLRHLARTARRFGEGELSARAETPAAHGELAELTRAFNAMADALAARQRE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AAESQGRLRAMSHRLAAAREAEAAAIARDLHDELGQVLTSVKVELAALQRAGAEGEDPAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
RRARVAELGQRLDEAVAFVRRVSSDLRPPVLDRLGLAAALEGLVRDLEQRTRLAVMLDVD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECC
PSVEPVEWLPAVTLFRIVREALTNVVRHAGATEVWIELRATPGALVLTVRDDGKGIGPWA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCCCCCCC
ADDRRSLGIQGMQERALLVDGTFEISGTPGGGTTVVVTIPRTRTGATDAAHPAG
CCCCHHCCCCCCCCCEEEEECEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA