| Definition | Anaeromyxobacter dehalogenans 2CP-1 chromosome, complete genome. |
|---|---|
| Accession | NC_011891 |
| Length | 5,029,329 |
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The map label for this gene is ftsH
Identifier: 220917260
GI number: 220917260
Start: 2397702
End: 2399822
Strand: Direct
Name: ftsH
Synonym: A2cp1_2158
Alternate gene names: 220917260
Gene position: 2397702-2399822 (Clockwise)
Preceding gene: 220917259
Following gene: 220917261
Centisome position: 47.67
GC content: 73.46
Gene sequence:
>2121_bases GTGTCCGCAGACGAGAAGAAGGGCCACGGGCAGCGCAGCGAGCGGGGGCGCGGGCCTGGCGGTCCTGGCACCCAGCCCCG GATCCCGCTGGCCTCGCCGGCGGCGTGGCTGGTCCTCATCGCGCTCGCCATCTTCCTGTTCCGCGCGTTCCAGGACGTGG GCGTGCGGCGCATCCCATACTCTCAGTTCAAGGAGATGGTGCGCCAGAGCGCGTTCGAGCGCGTCGTGATCGGGCCGGAC TGGGTCCGCGGCGTGCCGAAGCCGGTGGAGGCCGGGGCGGCGCAGGGCGGCGGCGCACAGCCGCAGCAGCAGGCGCAGGG CGAGGGCGAGCGCAACGGCCAGGCGCTGCCCTACGTCGCGACCCGCATCCCGGGAGGCGGCGACGACCTGGTGCAGGCGG TGGAGAAGGCCGGCGTGCCCTACGACGCGGTGGCCGGAGGCGGCATGGGCGACCTGTTCTGGGTCTGGATCGCGCCGATC GCGATCGGGCTGCTGTTCTGGGCCTGGGTGATGCGGCGCATGTCCGGGCAGCTCGGGCAGGGGCCGCCGGGGGTGATGGC GTTCGGGAAGTCGCGGGCCCGCATCCACATGGAGCCGGACACCGGCGTCACGTTCCAGGACGCGGCCGGCATCGACGAGG CGGTCGAGGAGCTGCAGGAGATCGTCGAGTTCCTGAAGACGCCGGAGAAGTACCGGCGGCTCGGCGGCCGGATCCCGAAG GGCGTGCTGCTGGTCGGGCCTCCCGGCACCGGCAAGACGCTGCTCGCGCGCGCCACCGCGGGCGAGGCCGGCGTGCCGTT CTTCTCGCTCTCCGGCTCGGAGTTCGTGGAGATGTTCGTGGGCGTGGGCGCGGCGCGCGTCCGCGACCTGTTCGCGCAGG CCACGCAGAAGGCGCCCTGCATCGTGTTCATCGACGAGCTGGACGCGCTCGGCAAGTCGCGCAACGCCGGCATCATGGGC GGGCACGACGAGCGCGAGCAGACGCTGAACCAGCTCCTCGCCGAGATGGACGGCTTCGACGCGCGCGCCGGCCTCATCAT CATGGGCGCCACCAACCGGCCGGAGATCCTCGATCCGGCGCTGCTGCGCCCGGGCCGCTTCGATCGCCAGGTGCTGGTGG ATCGGCCCGACAAGCGCGGCCGCGAGCAGATCCTCCGGATCCACGCACGCAACGTGAAGCTCGGGCCGGACGTGGACCTC CGCTCGGTGGCCGCGCGCACCCCCGGGTTCGCCGGCGCCGACCTCGCCAACGTGGTGAACGAGGCCGCGCTGCTCGCCGC GCGCCGCAACAAGAACCACGTGACCCGCGCCGAGTTCGAGGAGGCCATCGAGCGGGTGGTGGCGGGCCTCGAGAAGAAGA GCCGGCGCATCAACGAGCGCGAGAAGGAGATCGTCGCGTTCCACGAGGCCGGGCACGCGCTGGTGTCCTGGATGCTGCCG TTCGCGGACCGGGTCTCGAAGGTCTCGATCATCCCGCGCGGCCTGGGGGCGCTGGGCTACACGCTCCAGCTCCCGCTCGA GGACCGGTACCTGCTCACCCGCAGCGAGCTGCGCGACCGGATGGCGGGCCTGATGGGCGGGCGCGTCGCCGAGGAGGAGG TGTTCGGCGAGCCGTCCACCGGCGCGTCGAACGACCTGCAGCACGCCACCGCGGTGGCCCGGATGATGGTGCGCGACTAC GGCATGAGCCCGGCGCTCGGGCCGGTGTCGCTGGGCGACCAGAACGGCCCGAGCTTCCTGGGGGTGAAGGGGTTCGAGAC CCGGTCGTACTCCGACCACACCGCGCTGGCGGTCGATCGCGAGGTCCAGGCGCTGGTGGAGGAGGCGCAGGACCGCGCGC GGACGGTGGTGCGCGAGCACCGCGAGCGGCTCGAGGCGCTCGCGGCGCGCCTGCTCACGATCGAGGTGGTCGAGGAGGAC GAGATCACGCGCCTGTGGGGACCGAAGGTGGTGCGGCCCGGGACGATCGAGGGGCGCGGCCACGAGGAGTCGCCGCCCGA GACGCCGAACCGTCCGGTCGCGGCCTCGGCGGACGCGAGCGCGGGCTTCGGGAGGTCGGGGCCGCAGCCGCCGCAGGCGC TCGCGCGCCACGCCGGCGGCGACCCGGATCCCGAATCGTGA
Upstream 100 bases:
>100_bases GCCCCCACCGGCGAGCAGCCTGCCGGGGCCTTCCGCGCTTACCCGGATTGCCCGATCCCCGGACGTGCGCAGATTGCCTG CGAAGGGGGCAGGAGGCTCG
Downstream 100 bases:
>100_bases GGAGGCGTCGCGGCGGTGAGGCACGGGAGCGAGAGCCACGAGGCGCGCAAGGCGCTCTTCCAGATCGGGATCCGGCGGGG CAGCCTGACCATCGCCGAGA
Product: ATP-dependent metalloprotease FtsH
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 706; Mature: 705
Protein sequence:
>706_residues MSADEKKGHGQRSERGRGPGGPGTQPRIPLASPAAWLVLIALAIFLFRAFQDVGVRRIPYSQFKEMVRQSAFERVVIGPD WVRGVPKPVEAGAAQGGGAQPQQQAQGEGERNGQALPYVATRIPGGGDDLVQAVEKAGVPYDAVAGGGMGDLFWVWIAPI AIGLLFWAWVMRRMSGQLGQGPPGVMAFGKSRARIHMEPDTGVTFQDAAGIDEAVEELQEIVEFLKTPEKYRRLGGRIPK GVLLVGPPGTGKTLLARATAGEAGVPFFSLSGSEFVEMFVGVGAARVRDLFAQATQKAPCIVFIDELDALGKSRNAGIMG GHDEREQTLNQLLAEMDGFDARAGLIIMGATNRPEILDPALLRPGRFDRQVLVDRPDKRGREQILRIHARNVKLGPDVDL RSVAARTPGFAGADLANVVNEAALLAARRNKNHVTRAEFEEAIERVVAGLEKKSRRINEREKEIVAFHEAGHALVSWMLP FADRVSKVSIIPRGLGALGYTLQLPLEDRYLLTRSELRDRMAGLMGGRVAEEEVFGEPSTGASNDLQHATAVARMMVRDY GMSPALGPVSLGDQNGPSFLGVKGFETRSYSDHTALAVDREVQALVEEAQDRARTVVREHRERLEALAARLLTIEVVEED EITRLWGPKVVRPGTIEGRGHEESPPETPNRPVAASADASAGFGRSGPQPPQALARHAGGDPDPES
Sequences:
>Translated_706_residues MSADEKKGHGQRSERGRGPGGPGTQPRIPLASPAAWLVLIALAIFLFRAFQDVGVRRIPYSQFKEMVRQSAFERVVIGPD WVRGVPKPVEAGAAQGGGAQPQQQAQGEGERNGQALPYVATRIPGGGDDLVQAVEKAGVPYDAVAGGGMGDLFWVWIAPI AIGLLFWAWVMRRMSGQLGQGPPGVMAFGKSRARIHMEPDTGVTFQDAAGIDEAVEELQEIVEFLKTPEKYRRLGGRIPK GVLLVGPPGTGKTLLARATAGEAGVPFFSLSGSEFVEMFVGVGAARVRDLFAQATQKAPCIVFIDELDALGKSRNAGIMG GHDEREQTLNQLLAEMDGFDARAGLIIMGATNRPEILDPALLRPGRFDRQVLVDRPDKRGREQILRIHARNVKLGPDVDL RSVAARTPGFAGADLANVVNEAALLAARRNKNHVTRAEFEEAIERVVAGLEKKSRRINEREKEIVAFHEAGHALVSWMLP FADRVSKVSIIPRGLGALGYTLQLPLEDRYLLTRSELRDRMAGLMGGRVAEEEVFGEPSTGASNDLQHATAVARMMVRDY GMSPALGPVSLGDQNGPSFLGVKGFETRSYSDHTALAVDREVQALVEEAQDRARTVVREHRERLEALAARLLTIEVVEED EITRLWGPKVVRPGTIEGRGHEESPPETPNRPVAASADASAGFGRSGPQPPQALARHAGGDPDPES >Mature_705_residues SADEKKGHGQRSERGRGPGGPGTQPRIPLASPAAWLVLIALAIFLFRAFQDVGVRRIPYSQFKEMVRQSAFERVVIGPDW VRGVPKPVEAGAAQGGGAQPQQQAQGEGERNGQALPYVATRIPGGGDDLVQAVEKAGVPYDAVAGGGMGDLFWVWIAPIA IGLLFWAWVMRRMSGQLGQGPPGVMAFGKSRARIHMEPDTGVTFQDAAGIDEAVEELQEIVEFLKTPEKYRRLGGRIPKG VLLVGPPGTGKTLLARATAGEAGVPFFSLSGSEFVEMFVGVGAARVRDLFAQATQKAPCIVFIDELDALGKSRNAGIMGG HDEREQTLNQLLAEMDGFDARAGLIIMGATNRPEILDPALLRPGRFDRQVLVDRPDKRGREQILRIHARNVKLGPDVDLR SVAARTPGFAGADLANVVNEAALLAARRNKNHVTRAEFEEAIERVVAGLEKKSRRINEREKEIVAFHEAGHALVSWMLPF ADRVSKVSIIPRGLGALGYTLQLPLEDRYLLTRSELRDRMAGLMGGRVAEEEVFGEPSTGASNDLQHATAVARMMVRDYG MSPALGPVSLGDQNGPSFLGVKGFETRSYSDHTALAVDREVQALVEEAQDRARTVVREHRERLEALAARLLTIEVVEEDE ITRLWGPKVVRPGTIEGRGHEESPPETPNRPVAASADASAGFGRSGPQPPQALARHAGGDPDPES
Specific function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
COG id: COG0465
COG function: function code O; ATP-dependent Zn proteases
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the peptidase M41 family
Homologues:
Organism=Homo sapiens, GI300192933, Length=505, Percent_Identity=47.5247524752475, Blast_Score=454, Evalue=1e-127, Organism=Homo sapiens, GI4507173, Length=529, Percent_Identity=42.5330812854442, Blast_Score=406, Evalue=1e-113, Organism=Homo sapiens, GI21327685, Length=443, Percent_Identity=47.8555304740406, Blast_Score=397, Evalue=1e-110, Organism=Homo sapiens, GI7657689, Length=443, Percent_Identity=47.8555304740406, Blast_Score=396, Evalue=1e-110, Organism=Homo sapiens, GI24497435, Length=262, Percent_Identity=43.5114503816794, Blast_Score=220, Evalue=4e-57, Organism=Homo sapiens, GI4506209, Length=261, Percent_Identity=42.1455938697318, Blast_Score=213, Evalue=5e-55, Organism=Homo sapiens, GI24430151, Length=245, Percent_Identity=42.0408163265306, Blast_Score=207, Evalue=4e-53, Organism=Homo sapiens, GI21361144, Length=245, Percent_Identity=44.0816326530612, Blast_Score=205, Evalue=1e-52, Organism=Homo sapiens, GI195539395, Length=255, Percent_Identity=40, Blast_Score=204, Evalue=2e-52, Organism=Homo sapiens, GI6005942, Length=317, Percent_Identity=38.801261829653, Blast_Score=199, Evalue=8e-51, Organism=Homo sapiens, GI45643123, Length=282, Percent_Identity=39.7163120567376, Blast_Score=189, Evalue=8e-48, Organism=Homo sapiens, GI45643125, Length=282, Percent_Identity=39.7163120567376, Blast_Score=189, Evalue=8e-48, Organism=Homo sapiens, GI89064750, Length=257, Percent_Identity=39.6887159533074, Blast_Score=189, Evalue=9e-48, Organism=Homo sapiens, GI24430155, Length=257, Percent_Identity=39.6887159533074, Blast_Score=188, Evalue=1e-47, Organism=Homo sapiens, GI5729991, Length=257, Percent_Identity=39.6887159533074, Blast_Score=188, Evalue=1e-47, Organism=Homo sapiens, GI157671927, Length=270, Percent_Identity=37.037037037037, Blast_Score=179, Evalue=6e-45, Organism=Homo sapiens, GI24497618, Length=252, Percent_Identity=40.8730158730159, Blast_Score=178, Evalue=2e-44, Organism=Homo sapiens, GI40806173, Length=217, Percent_Identity=44.7004608294931, Blast_Score=174, Evalue=2e-43, Organism=Homo sapiens, GI229577436, Length=280, Percent_Identity=36.0714285714286, Blast_Score=173, Evalue=5e-43, Organism=Homo sapiens, GI153792536, Length=241, Percent_Identity=41.0788381742739, Blast_Score=170, Evalue=5e-42, Organism=Homo sapiens, GI4505725, Length=215, Percent_Identity=39.5348837209302, Blast_Score=161, Evalue=2e-39, Organism=Homo sapiens, GI194018488, Length=246, Percent_Identity=41.869918699187, Blast_Score=161, Evalue=2e-39, Organism=Homo sapiens, GI14149767, Length=295, Percent_Identity=33.5593220338983, Blast_Score=152, Evalue=9e-37, Organism=Homo sapiens, GI62177112, Length=295, Percent_Identity=33.5593220338983, Blast_Score=152, Evalue=9e-37, Organism=Homo sapiens, GI31377644, Length=277, Percent_Identity=34.2960288808664, Blast_Score=152, Evalue=1e-36, Organism=Homo sapiens, GI5901990, Length=237, Percent_Identity=38.8185654008439, Blast_Score=150, Evalue=3e-36, Organism=Homo sapiens, GI156564401, Length=232, Percent_Identity=37.5, Blast_Score=140, Evalue=3e-33, Organism=Homo sapiens, GI310125282, Length=232, Percent_Identity=37.0689655172414, Blast_Score=138, Evalue=2e-32, Organism=Homo sapiens, GI310125280, Length=232, Percent_Identity=37.0689655172414, Blast_Score=137, Evalue=3e-32, Organism=Homo sapiens, GI40806170, Length=232, Percent_Identity=40.0862068965517, Blast_Score=131, Evalue=2e-30, Organism=Homo sapiens, GI11875211, Length=232, Percent_Identity=40.0862068965517, Blast_Score=131, Evalue=2e-30, Organism=Homo sapiens, GI7019569, Length=233, Percent_Identity=34.3347639484979, Blast_Score=130, Evalue=3e-30, Organism=Homo sapiens, GI31742536, Length=226, Percent_Identity=33.1858407079646, Blast_Score=127, Evalue=4e-29, Organism=Homo sapiens, GI112789543, Length=226, Percent_Identity=33.1858407079646, Blast_Score=127, Evalue=4e-29, Organism=Homo sapiens, GI17865802, Length=236, Percent_Identity=34.3220338983051, Blast_Score=126, Evalue=6e-29, Organism=Homo sapiens, GI226371754, Length=238, Percent_Identity=33.1932773109244, Blast_Score=124, Evalue=2e-28, Organism=Homo sapiens, GI64084766, Length=271, Percent_Identity=27.3062730627306, Blast_Score=97, Evalue=4e-20, Organism=Homo sapiens, GI116292174, Length=249, Percent_Identity=30.9236947791165, Blast_Score=77, Evalue=6e-14, Organism=Homo sapiens, GI75677353, Length=235, Percent_Identity=27.6595744680851, Blast_Score=71, Evalue=3e-12, Organism=Escherichia coli, GI1789568, Length=655, Percent_Identity=45.0381679389313, Blast_Score=521, Evalue=1e-149, Organism=Caenorhabditis elegans, GI71994521, Length=478, Percent_Identity=51.0460251046025, Blast_Score=433, Evalue=1e-121, Organism=Caenorhabditis elegans, GI115534323, Length=453, Percent_Identity=44.5916114790287, Blast_Score=386, Evalue=1e-107, Organism=Caenorhabditis elegans, GI17554264, Length=464, Percent_Identity=45.2586206896552, Blast_Score=368, Evalue=1e-102, Organism=Caenorhabditis elegans, GI17554786, Length=262, Percent_Identity=43.5114503816794, Blast_Score=226, Evalue=3e-59, Organism=Caenorhabditis elegans, GI25144281, Length=262, Percent_Identity=43.5114503816794, Blast_Score=223, Evalue=3e-58, Organism=Caenorhabditis elegans, GI25144278, Length=262, Percent_Identity=43.5114503816794, Blast_Score=223, Evalue=3e-58, Organism=Caenorhabditis elegans, GI17563248, Length=261, Percent_Identity=43.6781609195402, Blast_Score=214, Evalue=1e-55, Organism=Caenorhabditis elegans, GI17563250, Length=245, Percent_Identity=42.4489795918367, Blast_Score=206, Evalue=4e-53, Organism=Caenorhabditis elegans, GI71987364, Length=246, Percent_Identity=40.650406504065, Blast_Score=203, Evalue=2e-52, Organism=Caenorhabditis elegans, GI71987372, Length=252, Percent_Identity=40.4761904761905, Blast_Score=203, Evalue=2e-52, Organism=Caenorhabditis elegans, GI17532375, Length=275, Percent_Identity=39.2727272727273, Blast_Score=202, Evalue=5e-52, Organism=Caenorhabditis elegans, GI17508701, Length=255, Percent_Identity=40.7843137254902, Blast_Score=196, Evalue=4e-50, Organism=Caenorhabditis elegans, GI17531535, Length=241, Percent_Identity=43.1535269709544, Blast_Score=194, Evalue=2e-49, Organism=Caenorhabditis elegans, GI17505546, Length=251, Percent_Identity=41.4342629482072, Blast_Score=192, Evalue=5e-49, Organism=Caenorhabditis elegans, GI17554784, Length=309, Percent_Identity=35.2750809061489, Blast_Score=178, Evalue=1e-44, Organism=Caenorhabditis elegans, GI17537217, Length=282, Percent_Identity=38.6524822695035, Blast_Score=173, Evalue=2e-43, Organism=Caenorhabditis elegans, GI17508053, Length=254, Percent_Identity=40.1574803149606, Blast_Score=171, Evalue=1e-42, Organism=Caenorhabditis elegans, GI193206116, Length=246, Percent_Identity=39.0243902439024, Blast_Score=162, Evalue=4e-40, Organism=Caenorhabditis elegans, GI133931034, Length=246, Percent_Identity=39.0243902439024, Blast_Score=162, Evalue=5e-40, Organism=Caenorhabditis elegans, GI193206114, Length=246, Percent_Identity=39.0243902439024, Blast_Score=162, Evalue=5e-40, Organism=Caenorhabditis elegans, GI25153574, Length=232, Percent_Identity=37.9310344827586, Blast_Score=153, Evalue=3e-37, Organism=Caenorhabditis elegans, GI17570397, Length=165, Percent_Identity=47.2727272727273, Blast_Score=150, Evalue=2e-36, Organism=Caenorhabditis elegans, GI32566590, Length=165, Percent_Identity=47.2727272727273, Blast_Score=150, Evalue=2e-36, Organism=Caenorhabditis elegans, GI193209502, Length=231, Percent_Identity=37.6623376623377, Blast_Score=150, Evalue=2e-36, Organism=Caenorhabditis elegans, GI17562804, Length=282, Percent_Identity=33.3333333333333, Blast_Score=139, Evalue=5e-33, Organism=Caenorhabditis elegans, GI133901658, Length=260, Percent_Identity=35, Blast_Score=139, Evalue=8e-33, Organism=Caenorhabditis elegans, GI133901662, Length=260, Percent_Identity=35, Blast_Score=138, Evalue=9e-33, Organism=Caenorhabditis elegans, GI86561515, Length=233, Percent_Identity=35.1931330472103, Blast_Score=133, Evalue=4e-31, Organism=Caenorhabditis elegans, GI25146157, Length=249, Percent_Identity=35.3413654618474, Blast_Score=128, Evalue=1e-29, Organism=Caenorhabditis elegans, GI17541226, Length=234, Percent_Identity=33.7606837606838, Blast_Score=119, Evalue=7e-27, Organism=Caenorhabditis elegans, GI17541224, Length=234, Percent_Identity=33.7606837606838, Blast_Score=119, Evalue=7e-27, Organism=Caenorhabditis elegans, GI32563584, Length=269, Percent_Identity=33.8289962825279, Blast_Score=118, Evalue=9e-27, Organism=Caenorhabditis elegans, GI17508421, Length=266, Percent_Identity=34.2105263157895, Blast_Score=118, Evalue=1e-26, Organism=Caenorhabditis elegans, GI17560432, Length=237, Percent_Identity=35.0210970464135, Blast_Score=112, Evalue=5e-25, Organism=Saccharomyces cerevisiae, GI6323736, Length=497, Percent_Identity=48.4909456740443, Blast_Score=468, Evalue=1e-132, Organism=Saccharomyces cerevisiae, GI6320854, Length=499, Percent_Identity=49.0981963927856, Blast_Score=461, Evalue=1e-130, Organism=Saccharomyces cerevisiae, GI6325281, Length=447, Percent_Identity=48.0984340044743, Blast_Score=397, Evalue=1e-111, Organism=Saccharomyces cerevisiae, GI6321390, Length=250, Percent_Identity=43.6, Blast_Score=214, Evalue=3e-56, Organism=Saccharomyces cerevisiae, GI6322704, Length=261, Percent_Identity=42.5287356321839, Blast_Score=214, Evalue=4e-56, Organism=Saccharomyces cerevisiae, GI6320197, Length=256, Percent_Identity=40.234375, Blast_Score=205, Evalue=2e-53, Organism=Saccharomyces cerevisiae, GI6324833, Length=245, Percent_Identity=42.4489795918367, Blast_Score=204, Evalue=4e-53, Organism=Saccharomyces cerevisiae, GI6324691, Length=256, Percent_Identity=42.578125, Blast_Score=203, Evalue=7e-53, Organism=Saccharomyces cerevisiae, GI6320077, Length=231, Percent_Identity=44.5887445887446, Blast_Score=196, Evalue=1e-50, Organism=Saccharomyces cerevisiae, GI6320602, Length=247, Percent_Identity=40.8906882591093, Blast_Score=183, Evalue=9e-47, Organism=Saccharomyces cerevisiae, GI6322994, Length=213, Percent_Identity=39.4366197183099, Blast_Score=169, Evalue=2e-42, Organism=Saccharomyces cerevisiae, GI6321709, Length=245, Percent_Identity=38.7755102040816, Blast_Score=164, Evalue=3e-41, Organism=Saccharomyces cerevisiae, GI6323429, Length=252, Percent_Identity=36.9047619047619, Blast_Score=160, Evalue=6e-40, Organism=Saccharomyces cerevisiae, GI6324000, Length=270, Percent_Identity=37.037037037037, Blast_Score=159, Evalue=1e-39, Organism=Saccharomyces cerevisiae, GI6322651, Length=260, Percent_Identity=35, Blast_Score=154, Evalue=5e-38, Organism=Saccharomyces cerevisiae, GI6321465, Length=234, Percent_Identity=37.1794871794872, Blast_Score=137, Evalue=4e-33, Organism=Saccharomyces cerevisiae, GI6325431, Length=235, Percent_Identity=38.2978723404255, Blast_Score=135, Evalue=2e-32, Organism=Saccharomyces cerevisiae, GI6319554, Length=251, Percent_Identity=35.8565737051793, Blast_Score=132, Evalue=3e-31, Organism=Saccharomyces cerevisiae, GI6325183, Length=260, Percent_Identity=31.5384615384615, Blast_Score=116, Evalue=1e-26, Organism=Saccharomyces cerevisiae, GI6320887, Length=246, Percent_Identity=30.4878048780488, Blast_Score=105, Evalue=2e-23, Organism=Saccharomyces cerevisiae, GI6320583, Length=235, Percent_Identity=27.2340425531915, Blast_Score=78, Evalue=6e-15, Organism=Drosophila melanogaster, GI28574878, Length=489, Percent_Identity=48.6707566462168, Blast_Score=459, Evalue=1e-129, Organism=Drosophila melanogaster, GI24665814, Length=489, Percent_Identity=48.6707566462168, Blast_Score=458, Evalue=1e-129, Organism=Drosophila melanogaster, GI24639391, Length=453, Percent_Identity=46.1368653421634, Blast_Score=410, Evalue=1e-114, Organism=Drosophila melanogaster, GI24658770, Length=460, Percent_Identity=46.0869565217391, Blast_Score=390, Evalue=1e-108, Organism=Drosophila melanogaster, GI19920408, Length=262, Percent_Identity=43.1297709923664, Blast_Score=220, Evalue=3e-57, Organism=Drosophila melanogaster, GI17137738, Length=261, Percent_Identity=42.911877394636, Blast_Score=215, Evalue=9e-56, Organism=Drosophila melanogaster, GI17738151, Length=255, Percent_Identity=44.3137254901961, Blast_Score=213, Evalue=5e-55, Organism=Drosophila melanogaster, GI24651451, Length=261, Percent_Identity=42.1455938697318, Blast_Score=210, Evalue=2e-54, Organism=Drosophila melanogaster, GI24649446, Length=245, Percent_Identity=42.0408163265306, Blast_Score=205, Evalue=7e-53, Organism=Drosophila melanogaster, GI281365776, Length=275, Percent_Identity=41.0909090909091, Blast_Score=204, Evalue=1e-52, Organism=Drosophila melanogaster, GI24660075, Length=275, Percent_Identity=41.0909090909091, Blast_Score=204, Evalue=1e-52, Organism=Drosophila melanogaster, GI45552965, Length=275, Percent_Identity=41.0909090909091, Blast_Score=204, Evalue=2e-52, Organism=Drosophila melanogaster, GI17137560, Length=244, Percent_Identity=43.4426229508197, Blast_Score=203, Evalue=3e-52, Organism=Drosophila melanogaster, GI161076488, Length=244, Percent_Identity=43.4426229508197, Blast_Score=203, Evalue=3e-52, Organism=Drosophila melanogaster, GI161076486, Length=244, Percent_Identity=43.4426229508197, Blast_Score=203, Evalue=4e-52, Organism=Drosophila melanogaster, GI24640100, Length=245, Percent_Identity=40.8163265306122, Blast_Score=199, Evalue=7e-51, Organism=Drosophila melanogaster, GI45554047, Length=166, Percent_Identity=54.8192771084337, Blast_Score=198, Evalue=1e-50, Organism=Drosophila melanogaster, GI24663015, Length=255, Percent_Identity=39.6078431372549, Blast_Score=194, Evalue=1e-49, Organism=Drosophila melanogaster, GI281361487, Length=245, Percent_Identity=40, Blast_Score=187, Evalue=2e-47, Organism=Drosophila melanogaster, GI18860063, Length=248, Percent_Identity=39.9193548387097, Blast_Score=184, Evalue=1e-46, Organism=Drosophila melanogaster, GI24652279, Length=205, Percent_Identity=46.3414634146341, Blast_Score=182, Evalue=7e-46, Organism=Drosophila melanogaster, GI19921202, Length=250, Percent_Identity=39.2, Blast_Score=173, Evalue=3e-43, Organism=Drosophila melanogaster, GI281363136, Length=269, Percent_Identity=38.2899628252788, Blast_Score=157, Evalue=2e-38, Organism=Drosophila melanogaster, GI78707192, Length=269, Percent_Identity=38.2899628252788, Blast_Score=157, Evalue=2e-38, Organism=Drosophila melanogaster, GI24656820, Length=228, Percent_Identity=36.4035087719298, Blast_Score=157, Evalue=3e-38, Organism=Drosophila melanogaster, GI24656825, Length=228, Percent_Identity=36.4035087719298, Blast_Score=157, Evalue=3e-38, Organism=Drosophila melanogaster, GI24644145, Length=239, Percent_Identity=37.2384937238494, Blast_Score=146, Evalue=5e-35, Organism=Drosophila melanogaster, GI20129423, Length=235, Percent_Identity=36.5957446808511, Blast_Score=144, Evalue=2e-34, Organism=Drosophila melanogaster, GI281360144, Length=233, Percent_Identity=36.480686695279, Blast_Score=143, Evalue=5e-34, Organism=Drosophila melanogaster, GI281360140, Length=233, Percent_Identity=36.480686695279, Blast_Score=143, Evalue=5e-34, Organism=Drosophila melanogaster, GI281360136, Length=233, Percent_Identity=36.480686695279, Blast_Score=143, Evalue=5e-34, Organism=Drosophila melanogaster, GI24644411, Length=233, Percent_Identity=36.480686695279, Blast_Score=143, Evalue=5e-34, Organism=Drosophila melanogaster, GI281360142, Length=233, Percent_Identity=36.480686695279, Blast_Score=142, Evalue=7e-34, Organism=Drosophila melanogaster, GI21357333, Length=233, Percent_Identity=36.480686695279, Blast_Score=142, Evalue=7e-34, Organism=Drosophila melanogaster, GI281360146, Length=233, Percent_Identity=36.480686695279, Blast_Score=142, Evalue=7e-34, Organism=Drosophila melanogaster, GI281360138, Length=233, Percent_Identity=36.480686695279, Blast_Score=142, Evalue=7e-34, Organism=Drosophila melanogaster, GI28573010, Length=248, Percent_Identity=37.5, Blast_Score=140, Evalue=2e-33, Organism=Drosophila melanogaster, GI21355121, Length=263, Percent_Identity=33.4600760456274, Blast_Score=139, Evalue=6e-33, Organism=Drosophila melanogaster, GI18859657, Length=232, Percent_Identity=36.6379310344828, Blast_Score=139, Evalue=8e-33, Organism=Drosophila melanogaster, GI17864540, Length=218, Percent_Identity=39.9082568807339, Blast_Score=139, Evalue=8e-33, Organism=Drosophila melanogaster, GI20129529, Length=237, Percent_Identity=33.3333333333333, Blast_Score=133, Evalue=3e-31, Organism=Drosophila melanogaster, GI24581396, Length=230, Percent_Identity=36.9565217391304, Blast_Score=126, Evalue=6e-29, Organism=Drosophila melanogaster, GI28571849, Length=230, Percent_Identity=38.695652173913, Blast_Score=125, Evalue=8e-29, Organism=Drosophila melanogaster, GI28571847, Length=230, Percent_Identity=38.695652173913, Blast_Score=125, Evalue=8e-29, Organism=Drosophila melanogaster, GI24639486, Length=286, Percent_Identity=28.3216783216783, Blast_Score=100, Evalue=4e-21,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): FTSH_ANAD2 (B8J992)
Other databases:
- EMBL: CP001359 - RefSeq: YP_002492564.1 - ProteinModelPortal: B8J992 - GeneID: 7297167 - GenomeReviews: CP001359_GR - KEGG: acp:A2cp1_2158 - HOGENOM: HBG724153 - ProtClustDB: CLSK945865 - GO: GO:0006508 - HAMAP: MF_01458 - InterPro: IPR003593 - InterPro: IPR003959 - InterPro: IPR003960 - InterPro: IPR005936 - InterPro: IPR011546 - InterPro: IPR000642 - SMART: SM00382 - TIGRFAMs: TIGR01241
Pfam domain/function: PF00004 AAA; PF06480 FtsH_ext; PF01434 Peptidase_M41
EC number: 3.4.24.-
Molecular weight: Translated: 76250; Mature: 76119
Theoretical pI: Translated: 6.67; Mature: 6.67
Prosite motif: PS00674 AAA
Important sites: ACT_SITE 469-469
Signals:
None
Transmembrane regions:
HASH(0x1c635378)-; HASH(0x1d694a94)-;
Cys/Met content:
0.1 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 2.5 %Cys+Met (Translated Protein) 0.1 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSADEKKGHGQRSERGRGPGGPGTQPRIPLASPAAWLVLIALAIFLFRAFQDVGVRRIPY CCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCH SQFKEMVRQSAFERVVIGPDWVRGVPKPVEAGAAQGGGAQPQQQAQGEGERNGQALPYVA HHHHHHHHHHHHCEEEECCHHHCCCCCCHHCCCCCCCCCCCHHHHCCCCCCCCCCCCCHH TRIPGGGDDLVQAVEKAGVPYDAVAGGGMGDLFWVWIAPIAIGLLFWAWVMRRMSGQLGQ CCCCCCHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC GPPGVMAFGKSRARIHMEPDTGVTFQDAAGIDEAVEELQEIVEFLKTPEKYRRLGGRIPK CCCCCEEECCCCCEEEECCCCCCCCHHHCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCC GVLLVGPPGTGKTLLARATAGEAGVPFFSLSGSEFVEMFVGVGAARVRDLFAQATQKAPC CEEEECCCCCCCEEEEEECCCCCCCCEEECCHHHHHHHHHHCCHHHHHHHHHHHHCCCCE IVFIDELDALGKSRNAGIMGGHDEREQTLNQLLAEMDGFDARAGLIIMGATNRPEILDPA EEEEHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHH LLRPGRFDRQVLVDRPDKRGREQILRIHARNVKLGPDVDLRSVAARTPGFAGADLANVVN HCCCCCCCCHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHH EAALLAARRNKNHVTRAEFEEAIERVVAGLEKKSRRINEREKEIVAFHEAGHALVSWMLP HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH FADRVSKVSIIPRGLGALGYTLQLPLEDRYLLTRSELRDRMAGLMGGRVAEEEVFGEPST HHHHHHHEECCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCC GASNDLQHATAVARMMVRDYGMSPALGPVSLGDQNGPSFLGVKGFETRSYSDHTALAVDR CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCHHEEHHH EVQALVEEAQDRARTVVREHRERLEALAARLLTIEVVEEDEITRLWGPKVVRPGTIEGRG HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHCCCCCCCCCCCCCCC HEESPPETPNRPVAASADASAGFGRSGPQPPQALARHAGGDPDPES CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCH >Mature Secondary Structure SADEKKGHGQRSERGRGPGGPGTQPRIPLASPAAWLVLIALAIFLFRAFQDVGVRRIPY CCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCH SQFKEMVRQSAFERVVIGPDWVRGVPKPVEAGAAQGGGAQPQQQAQGEGERNGQALPYVA HHHHHHHHHHHHCEEEECCHHHCCCCCCHHCCCCCCCCCCCHHHHCCCCCCCCCCCCCHH TRIPGGGDDLVQAVEKAGVPYDAVAGGGMGDLFWVWIAPIAIGLLFWAWVMRRMSGQLGQ CCCCCCHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC GPPGVMAFGKSRARIHMEPDTGVTFQDAAGIDEAVEELQEIVEFLKTPEKYRRLGGRIPK CCCCCEEECCCCCEEEECCCCCCCCHHHCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCC GVLLVGPPGTGKTLLARATAGEAGVPFFSLSGSEFVEMFVGVGAARVRDLFAQATQKAPC CEEEECCCCCCCEEEEEECCCCCCCCEEECCHHHHHHHHHHCCHHHHHHHHHHHHCCCCE IVFIDELDALGKSRNAGIMGGHDEREQTLNQLLAEMDGFDARAGLIIMGATNRPEILDPA EEEEHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHH LLRPGRFDRQVLVDRPDKRGREQILRIHARNVKLGPDVDLRSVAARTPGFAGADLANVVN HCCCCCCCCHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHH EAALLAARRNKNHVTRAEFEEAIERVVAGLEKKSRRINEREKEIVAFHEAGHALVSWMLP HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH FADRVSKVSIIPRGLGALGYTLQLPLEDRYLLTRSELRDRMAGLMGGRVAEEEVFGEPST HHHHHHHEECCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCC GASNDLQHATAVARMMVRDYGMSPALGPVSLGDQNGPSFLGVKGFETRSYSDHTALAVDR CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCHHEEHHH EVQALVEEAQDRARTVVREHRERLEALAARLLTIEVVEEDEITRLWGPKVVRPGTIEGRG HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHCCCCCCCCCCCCCCC HEESPPETPNRPVAASADASAGFGRSGPQPPQALARHAGGDPDPES CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCH
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA