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The map label for this gene is nudG [H]

Identifier: 220917259

GI number: 220917259

Start: 2397134

End: 2397523

Strand: Direct

Name: nudG [H]

Synonym: A2cp1_2157

Alternate gene names: 220917259

Gene position: 2397134-2397523 (Clockwise)

Preceding gene: 220917255

Following gene: 220917260

Centisome position: 47.66

GC content: 71.28

Gene sequence:

>390_bases
ATGCGCCGGAAGATCCGCGTGGTGGGAGCGATGATCGAGCAGGACGCGCGCTACCTCATCACCCAGCGCCCGCCCACCGC
CTCGCTGCCGCTGCTGTGGGAGTTCCCCGGCGGGCGCGTCGAGGCGGGCGAGACCGATCCCGCCGCGCTGGCGCGCGAGC
TCGCGGAGGAGATGGGCATCGGCGTCGAGGTCGGCGGCCGCGTGATCCACGTGGAGCACGCGTACGAGGCCTACGACATC
GACTTCTGCGTCTACCGCTGCCGCCTGGTCCGCGGCCCCATCCAGCACATCCGGGTGCACGACCACCGCTGGGTCCGGCC
CGACGAGCTCGATCAGTACGAGTTCCCGCCGGCCGACGAGAAGAGCATCGCGAAGCTGCTCGGCCTGTAG

Upstream 100 bases:

>100_bases
GGACGTCATCGTGAGCGAATTCTACAATCCCTGGACGCGCGCGGCGCGGCCCTCCCGCGCGCGGTGGGCACCACGGGACC
GCAGACGGAGCGTTCACGAC

Downstream 100 bases:

>100_bases
GGCCGGCCCGCCCCGGCCGTCCGCGCCGCGCAGCCCGCATGGGCGCGCAGGCTCCCGCTCCGCCTGACCCGACCGCAGGC
CCCCACCGGCGAGCAGCCTG

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 129; Mature: 129

Protein sequence:

>129_residues
MRRKIRVVGAMIEQDARYLITQRPPTASLPLLWEFPGGRVEAGETDPAALARELAEEMGIGVEVGGRVIHVEHAYEAYDI
DFCVYRCRLVRGPIQHIRVHDHRWVRPDELDQYEFPPADEKSIAKLLGL

Sequences:

>Translated_129_residues
MRRKIRVVGAMIEQDARYLITQRPPTASLPLLWEFPGGRVEAGETDPAALARELAEEMGIGVEVGGRVIHVEHAYEAYDI
DFCVYRCRLVRGPIQHIRVHDHRWVRPDELDQYEFPPADEKSIAKLLGL
>Mature_129_residues
MRRKIRVVGAMIEQDARYLITQRPPTASLPLLWEFPGGRVEAGETDPAALARELAEEMGIGVEVGGRVIHVEHAYEAYDI
DFCVYRCRLVRGPIQHIRVHDHRWVRPDELDQYEFPPADEKSIAKLLGL

Specific function: Specific for pyrimidine substrates. Acts on 5-methyl- dCTP, CTP and dCTP in decreasing order [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1788056, Length=141, Percent_Identity=36.1702127659575, Blast_Score=73, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.-

Molecular weight: Translated: 14745; Mature: 14745

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRKIRVVGAMIEQDARYLITQRPPTASLPLLWEFPGGRVEAGETDPAALARELAEEMGI
CCCHHHHHHHHHHCCCCEEEECCCCCCCCCEEEECCCCEEECCCCCHHHHHHHHHHHHCC
GVEVGGRVIHVEHAYEAYDIDFCVYRCRLVRGPIQHIRVHDHRWVRPDELDQYEFPPADE
CEECCCEEEEEECCCCCHHHHHHHHHHHHHHCCHHHEEECCCCCCCCCCCCCCCCCCCCH
KSIAKLLGL
HHHHHHHCC
>Mature Secondary Structure
MRRKIRVVGAMIEQDARYLITQRPPTASLPLLWEFPGGRVEAGETDPAALARELAEEMGI
CCCHHHHHHHHHHCCCCEEEECCCCCCCCCEEEECCCCEEECCCCCHHHHHHHHHHHHCC
GVEVGGRVIHVEHAYEAYDIDFCVYRCRLVRGPIQHIRVHDHRWVRPDELDQYEFPPADE
CEECCCEEEEEECCCCCHHHHHHHHHHHHHHCCHHHEEECCCCCCCCCCCCCCCCCCCCH
KSIAKLLGL
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 11053429 [H]