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The map label for this gene is pqqL [C]

Identifier: 220917181

GI number: 220917181

Start: 2319720

End: 2321045

Strand: Direct

Name: pqqL [C]

Synonym: A2cp1_2078

Alternate gene names: 220917181

Gene position: 2319720-2321045 (Clockwise)

Preceding gene: 220917179

Following gene: 220917182

Centisome position: 46.12

GC content: 73.23

Gene sequence:

>1326_bases
ATGGACGGGGCGTCCGGCCACGGCTATGTTCCGCGCCGGATGCCCAGCCAACCCGAGTCGCCCGCCCTGCTCGACCTCGC
GCAGGTCCGCGCGCACACCCTGCCGAACGGACTGCGGGTCCGCGTCCTGCCCGAGCGCAGCACCCCGACCGTCAGCTACT
ACACGTTCTTCCAGGTCGGCTCGCGCAACGAGCAGCTGGGCCTGACCGGCATCAGCCACCTGTTCGAGCACATGATGTTC
AACGGCGCGGCGCGTTACGGCCCGAAGGAGTTCGACCGGGTCCTGGAGGCGCGCGGCGGGCACTCGAACGCCTACACGTC
GAACGACGTGACCGCCTACTACGAGGACTTCGCCGCCGAGGCGCTGGAGACGGTGGTGGATCTCGAGTCGGATCGCATGC
GCTCGCTCCGCCTCACCGAGGACTCGCTCGAGCAGGAGCGCGAGGTCGTGAAGGAGGAGCGCCGGCTCCGCACCGAGAAC
TCGATCTTCGGCCTGATGGAGGAGCAGCTCGAGTCGCTCGTGTTCCTGTCGCACCCGTACCGCTGGCCGGTGATCGGCTG
GATGGAGGACATCCAGCGCATCGCCCGCGAGGACTGCGAGGCGTTCTTCCGGACGTACTACGCGCCCAGCAACGCGGCGG
TGTACGTGGTCGGCGACGTGGACCCGGACGACACGCTGCGGCTGGTGGAGCGGTATTACGCCGACATCCCGGCCGGCCCG
CGGCCCGCGCCCGTGCCCCAGGGCGAGCCGCCCCAGCGCGGCGAGCGTCGCGCCACCGTCCGCTATCCCGCGCAGGCGCC
GGCGCTGCTGGCGGGGTGGCGCGGCCCGGCGGCGCGCAGCCCGGACTCCGCCGCCCTCGACGTGCTGCAGGTCTGCCTGG
CGGTGGGCGAGTCGTCGCGCCTCCGCCGCCGGCTGGTGCAGGAGCTGGAACTGGCGGTGTCCGTCTCGATCAGCTGGGGC
TGGCGCATCGACCCGGGGGTGTTCCTGGCGTTCGCCGAGCTCGCGCCGGAGGTGTCGGTGGCGAGGGCGGAGAAGGAGCT
GTGGGCGGAGCTCGCCAAGGTGGCCGCGCGCGGGGTGACCGCCGCCGAGGTTCGCCGCGCGAAGGCGCTCCTGCGCAGCT
CGGTGCTGCACGAGCTCGCCACCCACCACGGCGTGGCGCACGCGCTCGGCCAGGCGGAGGCGCTGCTGGGCGACTGGCGG
GAGGCCGGCCGGGCGCTCGAGCACTACGCAGCGGTGGGCGTGCGGGACGTGCGACGCGTCGCGGCCGAGTACCTCGATCC
GACCCGCCGCTCGGTGGTGGTGCTCGACCCGGAGGTGCGGCGGTGA

Upstream 100 bases:

>100_bases
CACCCGAGGCAAGTGAACGTCCCCGGACCACGCGACTATTCCGGTGGAGGGCGGTGGCGCGCGCGGCGAGGGGGCGGGCG
GGCGCCGGGCCGTCCGCGCG

Downstream 100 bases:

>100_bases
GCCCCTCGATCGCGCTGCCGCCCATCCGCCGCGAGACGCTGCCCGGCGGCCTGCGGGTGATCGTCGCCGAGCGCAAGGGC
ATCCCGCTCGCCGCGGTGCG

Product: peptidase M16 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MDGASGHGYVPRRMPSQPESPALLDLAQVRAHTLPNGLRVRVLPERSTPTVSYYTFFQVGSRNEQLGLTGISHLFEHMMF
NGAARYGPKEFDRVLEARGGHSNAYTSNDVTAYYEDFAAEALETVVDLESDRMRSLRLTEDSLEQEREVVKEERRLRTEN
SIFGLMEEQLESLVFLSHPYRWPVIGWMEDIQRIAREDCEAFFRTYYAPSNAAVYVVGDVDPDDTLRLVERYYADIPAGP
RPAPVPQGEPPQRGERRATVRYPAQAPALLAGWRGPAARSPDSAALDVLQVCLAVGESSRLRRRLVQELELAVSVSISWG
WRIDPGVFLAFAELAPEVSVARAEKELWAELAKVAARGVTAAEVRRAKALLRSSVLHELATHHGVAHALGQAEALLGDWR
EAGRALEHYAAVGVRDVRRVAAEYLDPTRRSVVVLDPEVRR

Sequences:

>Translated_441_residues
MDGASGHGYVPRRMPSQPESPALLDLAQVRAHTLPNGLRVRVLPERSTPTVSYYTFFQVGSRNEQLGLTGISHLFEHMMF
NGAARYGPKEFDRVLEARGGHSNAYTSNDVTAYYEDFAAEALETVVDLESDRMRSLRLTEDSLEQEREVVKEERRLRTEN
SIFGLMEEQLESLVFLSHPYRWPVIGWMEDIQRIAREDCEAFFRTYYAPSNAAVYVVGDVDPDDTLRLVERYYADIPAGP
RPAPVPQGEPPQRGERRATVRYPAQAPALLAGWRGPAARSPDSAALDVLQVCLAVGESSRLRRRLVQELELAVSVSISWG
WRIDPGVFLAFAELAPEVSVARAEKELWAELAKVAARGVTAAEVRRAKALLRSSVLHELATHHGVAHALGQAEALLGDWR
EAGRALEHYAAVGVRDVRRVAAEYLDPTRRSVVVLDPEVRR
>Mature_441_residues
MDGASGHGYVPRRMPSQPESPALLDLAQVRAHTLPNGLRVRVLPERSTPTVSYYTFFQVGSRNEQLGLTGISHLFEHMMF
NGAARYGPKEFDRVLEARGGHSNAYTSNDVTAYYEDFAAEALETVVDLESDRMRSLRLTEDSLEQEREVVKEERRLRTEN
SIFGLMEEQLESLVFLSHPYRWPVIGWMEDIQRIAREDCEAFFRTYYAPSNAAVYVVGDVDPDDTLRLVERYYADIPAGP
RPAPVPQGEPPQRGERRATVRYPAQAPALLAGWRGPAARSPDSAALDVLQVCLAVGESSRLRRRLVQELELAVSVSISWG
WRIDPGVFLAFAELAPEVSVARAEKELWAELAKVAARGVTAAEVRRAKALLRSSVLHELATHHGVAHALGQAEALLGDWR
EAGRALEHYAAVGVRDVRRVAAEYLDPTRRSVVVLDPEVRR

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI46593007, Length=288, Percent_Identity=27.0833333333333, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI94538354, Length=436, Percent_Identity=23.394495412844, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI24308013, Length=200, Percent_Identity=30, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI155969707, Length=230, Percent_Identity=27.3913043478261, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI1787770, Length=214, Percent_Identity=27.1028037383178, Blast_Score=72, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71999683, Length=375, Percent_Identity=26.6666666666667, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17553678, Length=374, Percent_Identity=24.0641711229947, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994338, Length=144, Percent_Identity=30.5555555555556, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25146566, Length=144, Percent_Identity=30.5555555555556, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25146563, Length=144, Percent_Identity=30.5555555555556, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI32566665, Length=144, Percent_Identity=30.5555555555556, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323192, Length=394, Percent_Identity=25.8883248730964, Blast_Score=106, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6323421, Length=249, Percent_Identity=22.8915662650602, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357875, Length=441, Percent_Identity=24.2630385487528, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24646943, Length=441, Percent_Identity=24.2630385487528, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI19921772, Length=450, Percent_Identity=22.6666666666667, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 49274; Mature: 49274

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGASGHGYVPRRMPSQPESPALLDLAQVRAHTLPNGLRVRVLPERSTPTVSYYTFFQVG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEEEEC
SRNEQLGLTGISHLFEHMMFNGAARYGPKEFDRVLEARGGHSNAYTSNDVTAYYEDFAAE
CCCCCCCHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
ALETVVDLESDRMRSLRLTEDSLEQEREVVKEERRLRTENSIFGLMEEQLESLVFLSHPY
HHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RWPVIGWMEDIQRIAREDCEAFFRTYYAPSNAAVYVVGDVDPDDTLRLVERYYADIPAGP
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCC
RPAPVPQGEPPQRGERRATVRYPAQAPALLAGWRGPAARSPDSAALDVLQVCLAVGESSR
CCCCCCCCCCCCCCCCCCEEECCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCHHH
LRRRLVQELELAVSVSISWGWRIDPGVFLAFAELAPEVSVARAEKELWAELAKVAARGVT
HHHHHHHHHHHHEEEEEECCCEECHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCH
AAEVRRAKALLRSSVLHELATHHGVAHALGQAEALLGDWREAGRALEHYAAVGVRDVRRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAEYLDPTRRSVVVLDPEVRR
HHHHHCCCCCEEEEECCCCCC
>Mature Secondary Structure
MDGASGHGYVPRRMPSQPESPALLDLAQVRAHTLPNGLRVRVLPERSTPTVSYYTFFQVG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEEEEC
SRNEQLGLTGISHLFEHMMFNGAARYGPKEFDRVLEARGGHSNAYTSNDVTAYYEDFAAE
CCCCCCCHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
ALETVVDLESDRMRSLRLTEDSLEQEREVVKEERRLRTENSIFGLMEEQLESLVFLSHPY
HHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RWPVIGWMEDIQRIAREDCEAFFRTYYAPSNAAVYVVGDVDPDDTLRLVERYYADIPAGP
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCC
RPAPVPQGEPPQRGERRATVRYPAQAPALLAGWRGPAARSPDSAALDVLQVCLAVGESSR
CCCCCCCCCCCCCCCCCCEEECCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCHHH
LRRRLVQELELAVSVSISWGWRIDPGVFLAFAELAPEVSVARAEKELWAELAKVAARGVT
HHHHHHHHHHHHEEEEEECCCEECHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCH
AAEVRRAKALLRSSVLHELATHHGVAHALGQAEALLGDWREAGRALEHYAAVGVRDVRRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAEYLDPTRRSVVVLDPEVRR
HHHHHCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]