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The map label for this gene is map [H]

Identifier: 220917143

GI number: 220917143

Start: 2283467

End: 2284261

Strand: Direct

Name: map [H]

Synonym: A2cp1_2040

Alternate gene names: 220917143

Gene position: 2283467-2284261 (Clockwise)

Preceding gene: 220917142

Following gene: 220917144

Centisome position: 45.4

GC content: 75.72

Gene sequence:

>795_bases
ATGTACGGGACGACCCGCGAACGCGCCGCCACGCGGACCTCCGCCGACGTGGCCGGGATCCGCGCCGCCGGCCGCGTCGT
CTGGGAGGTGCTGGAGGCGCTGGCGGCCGCCGCCGCCCCGGGCGTCACCACCGCCGACCTGGATCGCCTCGCGGCCGCGC
GCACGCGCGAGCTCGGCGCGGCCCCGGCGTTCCTCGGCTACCACGGCTACCCCGCCACGCTCTGCATCTCGGTGAACGAC
GAGGTGATCCACGGGATCCCGTCGCCGGACCACGTGCTCGAGGAGGGCGACCTGGTCGGCCTCGACTTCGGGGCGGTGCT
CGACGGCTGGTACGGCGACTCGGCCCGGACGGTCGCGGTGGGACGGACCACGCCCGAGGGCGAGCGGCTGCTGGCCGTGA
CCCGGGCCGCGCTGGCGCGAGGCATCGCCGCGGCGCTCCCCGGGCGCCACACCGGCGACGTCGGCGCGGCCGTGCAGCGC
CACGTCGAGGCGGCGGGCTTCTCGGTGGTGCGCGACTTCGTGGGCCACGGCATCGGCCGCCGCCTGCACGAGCCGCCCCA
GGTCCCGAACTTCGGGACCCCCGGGACGGGGGCGCTCCTCCGGGCCGGTATGGTCATCGCCATCGAGCCGATGGTGAACG
CGGGCGGCCGCGAGGTCGAGACGCTCGACGACGGGTGGACCGCGGTGACGCGGGACGGGTCTCGATCCGCGCACTTCGAG
CACACCGTGGCCATCACGGAAAACGGACCGGAAGTCCTCACGTTGCCGGAAGGAGTGCCGCTGGAGGACGCCTGA

Upstream 100 bases:

>100_bases
GGCGAGCTGTCGGACGTCGAGGGCGTCGGCACGCCCGAGGGCATCCTCGCCGTGACGAAGAAGGTCCTGGGCCGCTAGGC
CCGGCCCGCACCGCCAGCGC

Downstream 100 bases:

>100_bases
CCGCAGGCGAGCGGGGGAGCGGGCGACGACGGGCCGTCGCTCGTGCTTGCACCCCAAAATCCTCTGTGTTATAGGGCCCG
CTTCGCAAAGCCGCTCGTTC

Product: methionine aminopeptidase, type I

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MYGTTRERAATRTSADVAGIRAAGRVVWEVLEALAAAAAPGVTTADLDRLAAARTRELGAAPAFLGYHGYPATLCISVND
EVIHGIPSPDHVLEEGDLVGLDFGAVLDGWYGDSARTVAVGRTTPEGERLLAVTRAALARGIAAALPGRHTGDVGAAVQR
HVEAAGFSVVRDFVGHGIGRRLHEPPQVPNFGTPGTGALLRAGMVIAIEPMVNAGGREVETLDDGWTAVTRDGSRSAHFE
HTVAITENGPEVLTLPEGVPLEDA

Sequences:

>Translated_264_residues
MYGTTRERAATRTSADVAGIRAAGRVVWEVLEALAAAAAPGVTTADLDRLAAARTRELGAAPAFLGYHGYPATLCISVND
EVIHGIPSPDHVLEEGDLVGLDFGAVLDGWYGDSARTVAVGRTTPEGERLLAVTRAALARGIAAALPGRHTGDVGAAVQR
HVEAAGFSVVRDFVGHGIGRRLHEPPQVPNFGTPGTGALLRAGMVIAIEPMVNAGGREVETLDDGWTAVTRDGSRSAHFE
HTVAITENGPEVLTLPEGVPLEDA
>Mature_264_residues
MYGTTRERAATRTSADVAGIRAAGRVVWEVLEALAAAAAPGVTTADLDRLAAARTRELGAAPAFLGYHGYPATLCISVND
EVIHGIPSPDHVLEEGDLVGLDFGAVLDGWYGDSARTVAVGRTTPEGERLLAVTRAALARGIAAALPGRHTGDVGAAVQR
HVEAAGFSVVRDFVGHGIGRRLHEPPQVPNFGTPGTGALLRAGMVIAIEPMVNAGGREVETLDDGWTAVTRDGSRSAHFE
HTVAITENGPEVLTLPEGVPLEDA

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=242, Percent_Identity=39.6694214876033, Blast_Score=194, Evalue=7e-50,
Organism=Homo sapiens, GI40385867, Length=243, Percent_Identity=32.9218106995885, Blast_Score=147, Evalue=7e-36,
Organism=Escherichia coli, GI1786364, Length=247, Percent_Identity=45.748987854251, Blast_Score=244, Evalue=4e-66,
Organism=Caenorhabditis elegans, GI71996291, Length=247, Percent_Identity=39.2712550607287, Blast_Score=186, Evalue=7e-48,
Organism=Saccharomyces cerevisiae, GI6323273, Length=239, Percent_Identity=37.6569037656904, Blast_Score=178, Evalue=8e-46,
Organism=Drosophila melanogaster, GI21355531, Length=239, Percent_Identity=38.9121338912134, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24583427, Length=252, Percent_Identity=34.9206349206349, Blast_Score=177, Evalue=6e-45,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 27414; Mature: 27414

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYGTTRERAATRTSADVAGIRAAGRVVWEVLEALAAAAAPGVTTADLDRLAAARTRELGA
CCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC
APAFLGYHGYPATLCISVNDEVIHGIPSPDHVLEEGDLVGLDFGAVLDGWYGDSARTVAV
CCHHHCCCCCCEEEEEEECHHHEECCCCHHHHHCCCCEEEEEHHHHHCCCCCCCCCEEEE
GRTTPEGERLLAVTRAALARGIAAALPGRHTGDVGAAVQRHVEAAGFSVVRDFVGHGIGR
ECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLHEPPQVPNFGTPGTGALLRAGMVIAIEPMVNAGGREVETLDDGWTAVTRDGSRSAHFE
HCCCCCCCCCCCCCCCHHHHHCCEEEEEECCCCCCCCEEEECCCCCEEEECCCCCCCCEE
HTVAITENGPEVLTLPEGVPLEDA
EEEEEECCCCEEEECCCCCCCCCC
>Mature Secondary Structure
MYGTTRERAATRTSADVAGIRAAGRVVWEVLEALAAAAAPGVTTADLDRLAAARTRELGA
CCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC
APAFLGYHGYPATLCISVNDEVIHGIPSPDHVLEEGDLVGLDFGAVLDGWYGDSARTVAV
CCHHHCCCCCCEEEEEEECHHHEECCCCHHHHHCCCCEEEEEHHHHHCCCCCCCCCEEEE
GRTTPEGERLLAVTRAALARGIAAALPGRHTGDVGAAVQRHVEAAGFSVVRDFVGHGIGR
ECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLHEPPQVPNFGTPGTGALLRAGMVIAIEPMVNAGGREVETLDDGWTAVTRDGSRSAHFE
HCCCCCCCCCCCCCCCHHHHHCCEEEEEECCCCCCCCEEEECCCCCEEEECCCCCCCCEE
HTVAITENGPEVLTLPEGVPLEDA
EEEEEECCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]