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The map label for this gene is plsC [H]

Identifier: 220916982

GI number: 220916982

Start: 2110060

End: 2110875

Strand: Reverse

Name: plsC [H]

Synonym: A2cp1_1878

Alternate gene names: 220916982

Gene position: 2110875-2110060 (Counterclockwise)

Preceding gene: 220916985

Following gene: 220916980

Centisome position: 41.97

GC content: 77.7

Gene sequence:

>816_bases
GTGGCCGGCGGGCGCCCGGCCCGCTACCCTGTTCCCGTGCGCCGCCTGCTCGCCACCGCCCTCACCTACGCGCTCGCCGG
GGCGGTGGTGGCCGTGTCCTTCCCGCTCGCGCTCGGCCTGTTCCTGCTCACCGCGCCGTTCGACCGGCGGCGGATGGCGG
TGAGCGAGCTGCTCCGCTGGCTGGGCGAGGTGCTGCTGCGCCACGCGCCGCTCTGGCCGGCGCGCATCGAGGGGTCGCTC
CCGCCGCCGCCCGCCACGTTCGTGGTCGTGCCGAACCACCAGTCCATCGTGGACGCGATCGCGGTCGCGTGCCTGCCCCG
CAACATGAAGTGGCTCGGCAAGGTGGAGGCATTCCGGCTGCCCTGGCTCGGCTGGGCGTTCCACCTCGCCGGCTACGTGC
CGGTGAAGCGCGGCGATCGCGCCAGCGGCGCGGCGGCGCTGGCGGCGATGCGGCGCTGGCTGGAGGCGGGGGTGCCGGTG
GGCCTGTTCGCCGAGGGGCACCGCACCCGCGACGGCCTGCTCCAGCCGTTCCACGCCGGACCGTTCCGCCTGGCCGTGGA
CCTGGGCGTGCCCATCGTGCCGGTGGCGATCTCCGGCGCCTGGCGCGCCATGCCGCCGGACCGCGCGGCCATCCGGCCCG
CCACCATCCAGGTGCGGATCCTGCCGCCGGTGCCGACCGTGGGCCGGACGCCGGCCGACGTGGATGCGCTCCGCGAGGAG
GTGCGCGGCCGGATCGCGGCGGCGCTGGCGGAGCTGGAGGCCCCCGCCGCGCCGCCGCGGGCCGCGCCGGCTACGCCTGC
TCCAGGATCGCGGTGA

Upstream 100 bases:

>100_bases
GGTTCACGAGCGCCGAGCCGTCGGAGAAGGCGATGAAGCGGGCCTGGGACATGGGGCGCGCACCCTACCCCGCCGCCCTG
ACAGCACCTCGGGGCGCAGC

Downstream 100 bases:

>100_bases
GCAGGCGCCAGAACGCCGCCACCGACGCGATCGAGACCCGCTCGTCCGGCGTGTGCGCGTCCCACATGCTCGGGCCGATG
GAGGCCATCTCCATGCCCGG

Product: 1-acylglycerol-3-phosphate O-acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT; Phosphatidic acid synthase; PA synthase [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MAGGRPARYPVPVRRLLATALTYALAGAVVAVSFPLALGLFLLTAPFDRRRMAVSELLRWLGEVLLRHAPLWPARIEGSL
PPPPATFVVVPNHQSIVDAIAVACLPRNMKWLGKVEAFRLPWLGWAFHLAGYVPVKRGDRASGAAALAAMRRWLEAGVPV
GLFAEGHRTRDGLLQPFHAGPFRLAVDLGVPIVPVAISGAWRAMPPDRAAIRPATIQVRILPPVPTVGRTPADVDALREE
VRGRIAAALAELEAPAAPPRAAPATPAPGSR

Sequences:

>Translated_271_residues
MAGGRPARYPVPVRRLLATALTYALAGAVVAVSFPLALGLFLLTAPFDRRRMAVSELLRWLGEVLLRHAPLWPARIEGSL
PPPPATFVVVPNHQSIVDAIAVACLPRNMKWLGKVEAFRLPWLGWAFHLAGYVPVKRGDRASGAAALAAMRRWLEAGVPV
GLFAEGHRTRDGLLQPFHAGPFRLAVDLGVPIVPVAISGAWRAMPPDRAAIRPATIQVRILPPVPTVGRTPADVDALREE
VRGRIAAALAELEAPAAPPRAAPATPAPGSR
>Mature_270_residues
AGGRPARYPVPVRRLLATALTYALAGAVVAVSFPLALGLFLLTAPFDRRRMAVSELLRWLGEVLLRHAPLWPARIEGSLP
PPPATFVVVPNHQSIVDAIAVACLPRNMKWLGKVEAFRLPWLGWAFHLAGYVPVKRGDRASGAAALAAMRRWLEAGVPVG
LFAEGHRTRDGLLQPFHAGPFRLAVDLGVPIVPVAISGAWRAMPPDRAAIRPATIQVRILPPVPTVGRTPADVDALREEV
RGRIAAALAELEAPAAPPRAAPATPAPGSR

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the 2 position. This enzyme can utilize either acyl-CoA or acyl-ACP as the fatty acyl donor [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=212, Percent_Identity=32.0754716981132, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI15100175, Length=212, Percent_Identity=32.0754716981132, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI6041665, Length=152, Percent_Identity=33.5526315789474, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1789395, Length=207, Percent_Identity=25.1207729468599, Blast_Score=75, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24641614, Length=220, Percent_Identity=29.0909090909091, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24641612, Length=220, Percent_Identity=29.0909090909091, Blast_Score=81, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 28941; Mature: 28810

Theoretical pI: Translated: 11.94; Mature: 11.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGGRPARYPVPVRRLLATALTYALAGAVVAVSFPLALGLFLLTAPFDRRRMAVSELLRW
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LGEVLLRHAPLWPARIEGSLPPPPATFVVVPNHQSIVDAIAVACLPRNMKWLGKVEAFRL
HHHHHHHHCCCCHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCHHHHCHHHHCC
PWLGWAFHLAGYVPVKRGDRASGAAALAAMRRWLEAGVPVGLFAEGHRTRDGLLQPFHAG
CHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCHHCCCCCCCCC
PFRLAVDLGVPIVPVAISGAWRAMPPDRAAIRPATIQVRILPPVPTVGRTPADVDALREE
CEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHH
VRGRIAAALAELEAPAAPPRAAPATPAPGSR
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AGGRPARYPVPVRRLLATALTYALAGAVVAVSFPLALGLFLLTAPFDRRRMAVSELLRW
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LGEVLLRHAPLWPARIEGSLPPPPATFVVVPNHQSIVDAIAVACLPRNMKWLGKVEAFRL
HHHHHHHHCCCCHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCHHHHCHHHHCC
PWLGWAFHLAGYVPVKRGDRASGAAALAAMRRWLEAGVPVGLFAEGHRTRDGLLQPFHAG
CHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCHHCCCCCCCCC
PFRLAVDLGVPIVPVAISGAWRAMPPDRAAIRPATIQVRILPPVPTVGRTPADVDALREE
CEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHH
VRGRIAAALAELEAPAAPPRAAPATPAPGSR
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1557036; 9278503 [H]