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The map label for this gene is luxQ [H]

Identifier: 220916841

GI number: 220916841

Start: 1938523

End: 1940424

Strand: Reverse

Name: luxQ [H]

Synonym: A2cp1_1737

Alternate gene names: 220916841

Gene position: 1940424-1938523 (Counterclockwise)

Preceding gene: 220916842

Following gene: 220916840

Centisome position: 38.58

GC content: 77.76

Gene sequence:

>1902_bases
ATGGTGACCGTCGGCCGGCGGCTGCTCGTGCCCACCACGCTGCTCGCCGCCGTGGCCTGCGCGGCGCTGGCCTACGCGGC
GTGGTCGTCCGCGCAGCAGGCGCGCACGCTGGAGCGCGACGCCCGGGCGGTGCGGACCGCCATCTCGCTGGCGTTCGCGC
TCGGCGACGCCACGCACGAGGAGGAGCGCTGGTTCCTGACCTTGCCGCGCTCGCCCGGCGGCGTGCAGGAGACGCGCCTC
GACGAGGCCGGCGCGCGCATCGCCGGGCTGATGCGCGAGATCGAGGCGCTCCCGCTGCCGGCGCGCGTCGGGGACGTGTG
GCGCGAGTACGTGGAGGTCCGGGCCGCGCAGGACGCGCTCGGCGCCGAGATCCGCCGGGCCGCGCCGGGCGGCGGGCCGG
CGCTCGAGCGCGCCCTCGAGCGCTGGGGGCTGATGTCGTTCCGCAGCGAGGCGCTGCTGAAGGACGTGTCCGGCTACTAC
CTGCGCTTCCTCGACCGGATCGTGGTCGAGCTGCAGGCGCGCCGCGCCCGGGCCCTGTGGATCTCGGCGGCCACGGTGGT
GGTGGGCCTGCTCGCCGCCGCGGCGCTCTCGCTGCTGGCGGCGCGCGCGGTGGTGCGGCCGCTCGAGGACATCGCCCGCA
CCGCCGAGCGGATCGCCGAGACCAGCCTCCCCGCCGAGGTGGCGGGGGCGGAGCGGCCCGACGAGATCGGGACGCTCTCC
CGCGCCTTCAACCGGATGACCGGGCGGCTGGTCAGCGCCAACGCCCGCCTCACCGAGATCGACCGGCGCAAGGACGAGTT
CCTGGGGATGCTCTCGCACGAGCTCCGCAACCCGCTCGCGCCCATCCGCAGCGCGCTGCACCTGCTCTCGCACCCCGCCG
CCAGCCCGGCGCAGGGCCGGCGCGCCCTGCAGGTCATCGCCCGGCAGGTGGACCACCTCACCCGCATCGTGGACGACCTG
CTCGACGTCACCCGCATCGCGCGGGGGAAGATCGAGCTGCGCCGGGAGCGCATCGACCTCTCCGAGGTGATCGCCCGCAC
CGCCGAGGACTACCGCGACCTGCTCGACGATCGCCGCATCGCGCTCGAGGTCGAGCTGTCCGCCGGCCCGCTCTGGGCGG
ACGCCGACCCCACCCGCGTGGCGCAGGTGGTCGGCAACCTGCTCAGCAACGCGGCCAAGTTCACGCCCCCCGGCGGCCGG
GTCACCGTGCGCGCGGCGGCGCGCGAGGGGCGCGCGGTGATCCGGGTGATCGACACCGGCGTGGGCATGCCGCCGGAGCT
GCTCGGGCGGATCTTCGAGCCGTTCGTCCAGGCGGATCGGTCGCTGGCGCGGAGCGCGGGCGGGCTCGGGCTGGGGCTGT
CGCTGGTGAAGGGGATCGTGGAGCTGCACGGCGGGGCGGTGGAGGCCCGCAGCGCCGGGCCCGGCACCGGCAGCGAGCTG
GTGATCGAGCTGCCCCTGGCGGCCGGCGGCGCCGAGCCGCTGCTCGCGCCGCCGGCGGCGCCGGCCGGCGCGGCGGGGCC
GCGGCGCGTGCTGGTGGTGGACGACAACGTGGACGCGGCCGAGACGCTCGCCGAGCTGCTCCGCCACGCCGGGCACGAGG
TGGCCATCGCGCACGACGGTCCGGGCGCGCTGGCGGCGGCGCGCGCCGGCGCGCCCGACGTGGTGCTCTGCGACATCGGC
CTGCCGGGCATGAGCGGCTACGACGTGGCGCGGGCGCTCCGGCGGGAGCGCGGGCCGGGCCTGCTGCTGGTGGCGATCAG
CGGCTACGCGCTGCCCGAGGACGTGCACGCCGCCCACGAGGCCGGCTTCGACCGGCACCTCGCGAAGCCGCCGCGGCCGG
ACGAGGTCGAGCGGGCCGTCGCGTCGCCGCCGGCCGGGATCCGCGCCGGCGCGGGCGGCTGA

Upstream 100 bases:

>100_bases
CGCTGCGCGGCGACGCGCCCGACCTGCACCAGCTCGTCGCGCCCGCCCTGCTCGAGCAGGTGGCGCCCGAGGCGGTCATG
CTGCTCCCCGGGGACGCGCG

Downstream 100 bases:

>100_bases
CGGCGCACCGTCCGAGCACCGGCGGGCCGCCGCGCCCCGCGCGACCGGCGACGCGCCGGCGCGCGCCGTGCTAGACAGGC
GGGCTCGGAGGATCTCCCAT

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 633; Mature: 633

Protein sequence:

>633_residues
MVTVGRRLLVPTTLLAAVACAALAYAAWSSAQQARTLERDARAVRTAISLAFALGDATHEEERWFLTLPRSPGGVQETRL
DEAGARIAGLMREIEALPLPARVGDVWREYVEVRAAQDALGAEIRRAAPGGGPALERALERWGLMSFRSEALLKDVSGYY
LRFLDRIVVELQARRARALWISAATVVVGLLAAAALSLLAARAVVRPLEDIARTAERIAETSLPAEVAGAERPDEIGTLS
RAFNRMTGRLVSANARLTEIDRRKDEFLGMLSHELRNPLAPIRSALHLLSHPAASPAQGRRALQVIARQVDHLTRIVDDL
LDVTRIARGKIELRRERIDLSEVIARTAEDYRDLLDDRRIALEVELSAGPLWADADPTRVAQVVGNLLSNAAKFTPPGGR
VTVRAAAREGRAVIRVIDTGVGMPPELLGRIFEPFVQADRSLARSAGGLGLGLSLVKGIVELHGGAVEARSAGPGTGSEL
VIELPLAAGGAEPLLAPPAAPAGAAGPRRVLVVDDNVDAAETLAELLRHAGHEVAIAHDGPGALAAARAGAPDVVLCDIG
LPGMSGYDVARALRRERGPGLLLVAISGYALPEDVHAAHEAGFDRHLAKPPRPDEVERAVASPPAGIRAGAGG

Sequences:

>Translated_633_residues
MVTVGRRLLVPTTLLAAVACAALAYAAWSSAQQARTLERDARAVRTAISLAFALGDATHEEERWFLTLPRSPGGVQETRL
DEAGARIAGLMREIEALPLPARVGDVWREYVEVRAAQDALGAEIRRAAPGGGPALERALERWGLMSFRSEALLKDVSGYY
LRFLDRIVVELQARRARALWISAATVVVGLLAAAALSLLAARAVVRPLEDIARTAERIAETSLPAEVAGAERPDEIGTLS
RAFNRMTGRLVSANARLTEIDRRKDEFLGMLSHELRNPLAPIRSALHLLSHPAASPAQGRRALQVIARQVDHLTRIVDDL
LDVTRIARGKIELRRERIDLSEVIARTAEDYRDLLDDRRIALEVELSAGPLWADADPTRVAQVVGNLLSNAAKFTPPGGR
VTVRAAAREGRAVIRVIDTGVGMPPELLGRIFEPFVQADRSLARSAGGLGLGLSLVKGIVELHGGAVEARSAGPGTGSEL
VIELPLAAGGAEPLLAPPAAPAGAAGPRRVLVVDDNVDAAETLAELLRHAGHEVAIAHDGPGALAAARAGAPDVVLCDIG
LPGMSGYDVARALRRERGPGLLLVAISGYALPEDVHAAHEAGFDRHLAKPPRPDEVERAVASPPAGIRAGAGG
>Mature_633_residues
MVTVGRRLLVPTTLLAAVACAALAYAAWSSAQQARTLERDARAVRTAISLAFALGDATHEEERWFLTLPRSPGGVQETRL
DEAGARIAGLMREIEALPLPARVGDVWREYVEVRAAQDALGAEIRRAAPGGGPALERALERWGLMSFRSEALLKDVSGYY
LRFLDRIVVELQARRARALWISAATVVVGLLAAAALSLLAARAVVRPLEDIARTAERIAETSLPAEVAGAERPDEIGTLS
RAFNRMTGRLVSANARLTEIDRRKDEFLGMLSHELRNPLAPIRSALHLLSHPAASPAQGRRALQVIARQVDHLTRIVDDL
LDVTRIARGKIELRRERIDLSEVIARTAEDYRDLLDDRRIALEVELSAGPLWADADPTRVAQVVGNLLSNAAKFTPPGGR
VTVRAAAREGRAVIRVIDTGVGMPPELLGRIFEPFVQADRSLARSAGGLGLGLSLVKGIVELHGGAVEARSAGPGTGSEL
VIELPLAAGGAEPLLAPPAAPAGAAGPRRVLVVDDNVDAAETLAELLRHAGHEVAIAHDGPGALAAARAGAPDVVLCDIG
LPGMSGYDVARALRRERGPGLLLVAISGYALPEDVHAAHEAGFDRHLAKPPRPDEVERAVASPPAGIRAGAGG

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=364, Percent_Identity=32.1428571428571, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI87081816, Length=471, Percent_Identity=28.0254777070064, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788713, Length=354, Percent_Identity=27.683615819209, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI145693157, Length=226, Percent_Identity=31.858407079646, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1789149, Length=425, Percent_Identity=26.5882352941176, Blast_Score=113, Evalue=5e-26,
Organism=Escherichia coli, GI1786783, Length=331, Percent_Identity=25.0755287009063, Blast_Score=102, Evalue=8e-23,
Organism=Escherichia coli, GI1788393, Length=286, Percent_Identity=27.2727272727273, Blast_Score=102, Evalue=9e-23,
Organism=Escherichia coli, GI87082128, Length=277, Percent_Identity=25.9927797833935, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790436, Length=238, Percent_Identity=28.5714285714286, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1786600, Length=239, Percent_Identity=27.6150627615063, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1790861, Length=300, Percent_Identity=28, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1789808, Length=290, Percent_Identity=28.2758620689655, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790551, Length=286, Percent_Identity=29.7202797202797, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1788279, Length=289, Percent_Identity=24.5674740484429, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786912, Length=249, Percent_Identity=28.1124497991968, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1787894, Length=245, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790346, Length=300, Percent_Identity=27, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788549, Length=304, Percent_Identity=23.0263157894737, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1789403, Length=316, Percent_Identity=28.4810126582279, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1790300, Length=232, Percent_Identity=31.0344827586207, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67097; Mature: 67097

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50885 HAMP ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTVGRRLLVPTTLLAAVACAALAYAAWSSAQQARTLERDARAVRTAISLAFALGDATHE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EERWFLTLPRSPGGVQETRLDEAGARIAGLMREIEALPLPARVGDVWREYVEVRAAQDAL
CCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
GAEIRRAAPGGGPALERALERWGLMSFRSEALLKDVSGYYLRFLDRIVVELQARRARALW
HHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISAATVVVGLLAAAALSLLAARAVVRPLEDIARTAERIAETSLPAEVAGAERPDEIGTLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHH
RAFNRMTGRLVSANARLTEIDRRKDEFLGMLSHELRNPLAPIRSALHLLSHPAASPAQGR
HHHHHHHCHHEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHH
RALQVIARQVDHLTRIVDDLLDVTRIARGKIELRRERIDLSEVIARTAEDYRDLLDDRRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEE
ALEVELSAGPLWADADPTRVAQVVGNLLSNAAKFTPPGGRVTVRAAAREGRAVIRVIDTG
EEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEEEEECC
VGMPPELLGRIFEPFVQADRSLARSAGGLGLGLSLVKGIVELHGGAVEARSAGPGTGSEL
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEECCCCCCCCCCCE
VIELPLAAGGAEPLLAPPAAPAGAAGPRRVLVVDDNVDAAETLAELLRHAGHEVAIAHDG
EEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEECC
PGALAAARAGAPDVVLCDIGLPGMSGYDVARALRRERGPGLLLVAISGYALPEDVHAAHE
CCHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHH
AGFDRHLAKPPRPDEVERAVASPPAGIRAGAGG
CCCHHHCCCCCCCHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MVTVGRRLLVPTTLLAAVACAALAYAAWSSAQQARTLERDARAVRTAISLAFALGDATHE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EERWFLTLPRSPGGVQETRLDEAGARIAGLMREIEALPLPARVGDVWREYVEVRAAQDAL
CCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
GAEIRRAAPGGGPALERALERWGLMSFRSEALLKDVSGYYLRFLDRIVVELQARRARALW
HHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISAATVVVGLLAAAALSLLAARAVVRPLEDIARTAERIAETSLPAEVAGAERPDEIGTLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHH
RAFNRMTGRLVSANARLTEIDRRKDEFLGMLSHELRNPLAPIRSALHLLSHPAASPAQGR
HHHHHHHCHHEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHH
RALQVIARQVDHLTRIVDDLLDVTRIARGKIELRRERIDLSEVIARTAEDYRDLLDDRRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEE
ALEVELSAGPLWADADPTRVAQVVGNLLSNAAKFTPPGGRVTVRAAAREGRAVIRVIDTG
EEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEEEEECC
VGMPPELLGRIFEPFVQADRSLARSAGGLGLGLSLVKGIVELHGGAVEARSAGPGTGSEL
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEECCCCCCCCCCCE
VIELPLAAGGAEPLLAPPAAPAGAAGPRRVLVVDDNVDAAETLAELLRHAGHEVAIAHDG
EEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEECC
PGALAAARAGAPDVVLCDIGLPGMSGYDVARALRRERGPGLLLVAISGYALPEDVHAAHE
CCHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHH
AGFDRHLAKPPRPDEVERAVASPPAGIRAGAGG
CCCHHHCCCCCCCHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA