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The map label for this gene is mocR [H]

Identifier: 220916818

GI number: 220916818

Start: 1910506

End: 1911972

Strand: Reverse

Name: mocR [H]

Synonym: A2cp1_1714

Alternate gene names: 220916818

Gene position: 1911972-1910506 (Counterclockwise)

Preceding gene: 220916821

Following gene: 220916808

Centisome position: 38.02

GC content: 79.41

Gene sequence:

>1467_bases
ATGGATCCATTACCGTCCGGGAGCGTGGACCTGCACGTCTCCCTTCACCGCCGCGGCCGGCTCGCCGCCGACGCCTACCG
CCAGCTCCGGGAGGCCATCCTGGACGGCCGCCTGCGCGCCGGCGACCGGCTGCCCGCCACCCGCGACCTGGCCCGGCGCC
TGGACGTCTCGCGCAACACCGTGCTGCACGCGTACCAGCGGCTCGCGGCGGAAGGCTACCTGGTCGGCCGCGCGGGCGCG
GGGACCTACGTGGCGGAAGGGGTCCGCGCCGGCGCCGCCGGCCGGCGCGCGCCGGTCGGCGCGGCGCTGCAGCCGCGCGC
GGCCTGGGCGTCGATGCCCCCGCCGCCGGCTCCTCCCCCGCGTCCCGCGCCCTACGACTTCCAGGTCGGCGCGCCGGACC
CGGCGCTGTTCCCGTGGGACGCCTGGCGCTGGCGGGTGTCGCGCCAGCTCCGCGGCCGGCGGGCGCGCGCGGGCTACCCG
CCGCCCGAGGGCGATCCCGGCGCGCGCGCGGCGGTGGCGCGCCACCTGGGCGTGGCCCGCTCGGTGCGCGCCGGCGCGGA
GGACGTGATCCTCACCTCCGGCGCGCAGCAGGCGCTCGACCTGGTGGGGCGGGTGCTGCTCGCGCCCGGCGATCGCGTCG
CGCTCGAGGATCCGGGGTATCCGCCCGCCCGCGGCGCGTTCGAGGCGCTCGGCGCGCGCGCGGTGCCGGTGCGGGTGGAC
GCGGAGGGCCTGGTGGTGGAGGCGCTGCCCGCGGACGTGCGGCTCGTCTACGTCACGCCGTCGCACCAGTTCCCGCTGGG
CATGCCCATGTCGCTGCGCCGGCGGCAGGCGCTGCTCGCCTGGAGCGAGCGGACCGGCGCGGCGATCGTCGAGGACGACT
ACGACAGCGAGTTCCGCTTCGACGGCCGGCCGCTCGAGCCTCTGCAGGCGCTGGATCGCCAGGGGCGCGTCGTCTACGTG
GGCTCGCTCTCGAAGGTGCTGCTGCCGACGCTGCGGCTCGGGTTCCTGGTCGCCCCCGCCTCGCTCGTCCCGGCGCTGCG
CGCCGCGAAGGCCCTGGCGGACTCCCACGGGCCGCTCGAGCTGCAGCGCGCCCTCGCCGAGCTGGTGGACGACGGGCTCC
TGGCCCGCCACGTCCGCCGCGTGCTCCGGGTGTACCGGGAGCGCCGCGACCGGCTCGCCGCCGCCGTCGAGCGCCACCTC
GCCGGCCGCGTGATCGCGCTCCCGGCCTCGGCTGGCCTGCACTGGAGCTTCCTCCTCGCCGACGCAGGCGCGGACGAGGC
GGGGGTGGTCCGGCGCGCGCAGGCGCTGGGCGTGGCCGTCCAGCCGCTCGCGCCGTACCACGCGCGGCCGGGACGGCCCG
GCTTCGCGCTCGGCTACGGGATCATCCCCGCGGCCCGGATCGACGAGGGCGTCCGCCGGCTGGCGGCGGCGCTGGAGCCG
CCGCCCGCGGTGCGCGCGCGCCGGTGA

Upstream 100 bases:

>100_bases
GGCAGGTGATCGGTTCCGTCCGGGTGGTTCGGTTCGTGGGTCATGCCCTCCAGGTAGCGGCCGCAGTGGCTCCCTCACAG
GTCCACACTGGCGAAATCCA

Downstream 100 bases:

>100_bases
GCCGCCCTATCCGCGCTCCGGCCCGCCGCGGTCGTGCCCGCGCCCGCCGCGATCGCCGCCGCGGTCACCGCCCCGATCGC
CGCGGTCGGGTCCGCGATCG

Product: GntR family transcriptional regulator with aminotransferase domain

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MDPLPSGSVDLHVSLHRRGRLAADAYRQLREAILDGRLRAGDRLPATRDLARRLDVSRNTVLHAYQRLAAEGYLVGRAGA
GTYVAEGVRAGAAGRRAPVGAALQPRAAWASMPPPPAPPPRPAPYDFQVGAPDPALFPWDAWRWRVSRQLRGRRARAGYP
PPEGDPGARAAVARHLGVARSVRAGAEDVILTSGAQQALDLVGRVLLAPGDRVALEDPGYPPARGAFEALGARAVPVRVD
AEGLVVEALPADVRLVYVTPSHQFPLGMPMSLRRRQALLAWSERTGAAIVEDDYDSEFRFDGRPLEPLQALDRQGRVVYV
GSLSKVLLPTLRLGFLVAPASLVPALRAAKALADSHGPLELQRALAELVDDGLLARHVRRVLRVYRERRDRLAAAVERHL
AGRVIALPASAGLHWSFLLADAGADEAGVVRRAQALGVAVQPLAPYHARPGRPGFALGYGIIPAARIDEGVRRLAAALEP
PPAVRARR

Sequences:

>Translated_488_residues
MDPLPSGSVDLHVSLHRRGRLAADAYRQLREAILDGRLRAGDRLPATRDLARRLDVSRNTVLHAYQRLAAEGYLVGRAGA
GTYVAEGVRAGAAGRRAPVGAALQPRAAWASMPPPPAPPPRPAPYDFQVGAPDPALFPWDAWRWRVSRQLRGRRARAGYP
PPEGDPGARAAVARHLGVARSVRAGAEDVILTSGAQQALDLVGRVLLAPGDRVALEDPGYPPARGAFEALGARAVPVRVD
AEGLVVEALPADVRLVYVTPSHQFPLGMPMSLRRRQALLAWSERTGAAIVEDDYDSEFRFDGRPLEPLQALDRQGRVVYV
GSLSKVLLPTLRLGFLVAPASLVPALRAAKALADSHGPLELQRALAELVDDGLLARHVRRVLRVYRERRDRLAAAVERHL
AGRVIALPASAGLHWSFLLADAGADEAGVVRRAQALGVAVQPLAPYHARPGRPGFALGYGIIPAARIDEGVRRLAAALEP
PPAVRARR
>Mature_488_residues
MDPLPSGSVDLHVSLHRRGRLAADAYRQLREAILDGRLRAGDRLPATRDLARRLDVSRNTVLHAYQRLAAEGYLVGRAGA
GTYVAEGVRAGAAGRRAPVGAALQPRAAWASMPPPPAPPPRPAPYDFQVGAPDPALFPWDAWRWRVSRQLRGRRARAGYP
PPEGDPGARAAVARHLGVARSVRAGAEDVILTSGAQQALDLVGRVLLAPGDRVALEDPGYPPARGAFEALGARAVPVRVD
AEGLVVEALPADVRLVYVTPSHQFPLGMPMSLRRRQALLAWSERTGAAIVEDDYDSEFRFDGRPLEPLQALDRQGRVVYV
GSLSKVLLPTLRLGFLVAPASLVPALRAAKALADSHGPLELQRALAELVDDGLLARHVRRVLRVYRERRDRLAAAVERHL
AGRVIALPASAGLHWSFLLADAGADEAGVVRRAQALGVAVQPLAPYHARPGRPGFALGYGIIPAARIDEGVRRLAAALEP
PPAVRARR

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=291, Percent_Identity=25.085910652921, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI33469970, Length=291, Percent_Identity=25.085910652921, Blast_Score=103, Evalue=4e-22,
Organism=Escherichia coli, GI1787710, Length=401, Percent_Identity=29.925187032419, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1790797, Length=415, Percent_Identity=26.7469879518072, Blast_Score=113, Evalue=2e-26,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 52423; Mature: 52423

Theoretical pI: Translated: 11.41; Mature: 11.41

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPLPSGSVDLHVSLHRRGRLAADAYRQLREAILDGRLRAGDRLPATRDLARRLDVSRNT
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHH
VLHAYQRLAAEGYLVGRAGAGTYVAEGVRAGAAGRRAPVGAALQPRAAWASMPPPPAPPP
HHHHHHHHHHCCEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCC
RPAPYDFQVGAPDPALFPWDAWRWRVSRQLRGRRARAGYPPPEGDPGARAAVARHLGVAR
CCCCCCEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
SVRAGAEDVILTSGAQQALDLVGRVLLAPGDRVALEDPGYPPARGAFEALGARAVPVRVD
HHHCCCCCEEEECCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHCCCCEEEEEC
AEGLVVEALPADVRLVYVTPSHQFPLGMPMSLRRRQALLAWSERTGAAIVEDDYDSEFRF
CCCEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCEEE
DGRPLEPLQALDRQGRVVYVGSLSKVLLPTLRLGFLVAPASLVPALRAAKALADSHGPLE
CCCCCCHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHH
LQRALAELVDDGLLARHVRRVLRVYRERRDRLAAAVERHLAGRVIALPASAGLHWSFLLA
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEEE
DAGADEAGVVRRAQALGVAVQPLAPYHARPGRPGFALGYGIIPAARIDEGVRRLAAALEP
ECCCCHHHHHHHHHHHCEEECCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHCCC
PPAVRARR
CCCCCCCC
>Mature Secondary Structure
MDPLPSGSVDLHVSLHRRGRLAADAYRQLREAILDGRLRAGDRLPATRDLARRLDVSRNT
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHH
VLHAYQRLAAEGYLVGRAGAGTYVAEGVRAGAAGRRAPVGAALQPRAAWASMPPPPAPPP
HHHHHHHHHHCCEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCC
RPAPYDFQVGAPDPALFPWDAWRWRVSRQLRGRRARAGYPPPEGDPGARAAVARHLGVAR
CCCCCCEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
SVRAGAEDVILTSGAQQALDLVGRVLLAPGDRVALEDPGYPPARGAFEALGARAVPVRVD
HHHCCCCCEEEECCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHCCCCEEEEEC
AEGLVVEALPADVRLVYVTPSHQFPLGMPMSLRRRQALLAWSERTGAAIVEDDYDSEFRF
CCCEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCEEE
DGRPLEPLQALDRQGRVVYVGSLSKVLLPTLRLGFLVAPASLVPALRAAKALADSHGPLE
CCCCCCHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHH
LQRALAELVDDGLLARHVRRVLRVYRERRDRLAAAVERHLAGRVIALPASAGLHWSFLLA
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEEE
DAGADEAGVVRRAQALGVAVQPLAPYHARPGRPGFALGYGIIPAARIDEGVRRLAAALEP
ECCCCHHHHHHHHHHHCEEECCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHCCC
PPAVRARR
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]