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The map label for this gene is rutD [H]

Identifier: 220916800

GI number: 220916800

Start: 1888638

End: 1889492

Strand: Reverse

Name: rutD [H]

Synonym: A2cp1_1695

Alternate gene names: 220916800

Gene position: 1889492-1888638 (Counterclockwise)

Preceding gene: 220916801

Following gene: 220916799

Centisome position: 37.57

GC content: 76.61

Gene sequence:

>855_bases
ATGACCGCGCTCCTCCCCGCCGCCCTCGCCGCCGCGCTGCTCGCGGCCAGCCCCGCCGCGCCGAACGCCCCGGCGCGCGC
GCCCGCCGACCCGGTGCAGCGCGGCTACGCGCCGGTGAACGGCCTTCGCATCTACTACGAGCTCCACGGCCCCGCCGGCG
CGAAGGGGCCGCCGCTCGTGCTGCTCCACGGCGGCGGCTCGAGCATCGACACCTCCTTCGCGAGCCTGCTCCCCGCGCTC
GCGCGCCACCGCCGCGTGATCGCGTTCGACCAGCAGGGCCACGGCCGCACCGCCGACCTCCCCGACCGCCCGTTCACGTT
CGAGCAGTCGGCCGACGACACCGCGGCCCTGCTCCGGCACCTGGGCGTAGCGCGCGCCGACCTCCTCGGCTTCAGCAACG
GCGGGACCATCGCCCTGCAGGTCGCCGTCCGTCACCCCGCGCTGGTGCGGCGGCTGGTGGTGGCGTCGGCGATGGTGCGC
CGCGACGGCCTGGCGCCGCAGGCGTGGGAGGCGATCCGGCGCGGGCGCCTGGAGGACATGCCGGTCGAGCTGCGGCAGGC
GTACCTCGCGGTCGCGCCGCACCCCGACCAGCTCGCGTCCTTCCACGCGAAGTCGGCGCGCCGCATGCTCGAGTTCCGCG
ACTGGCCGGACGCCGAGGTGCGGTCGATCACGGTCCCGGTGCTCGTCGTGGCCGGGGACCGCGACGCCGTGCTGCCCGAG
CACGCGGTGGCGCTGACCCGCATGCTCCCGGACGCACGGCTGGCGGTGCTCCCCGCCACCGACCACGACGGCGTGGTGCA
ACGCCGCGTGGAGTGGCTCGGCCCGATGATCGAGGCGTTCCTGGACGAGCCGTAA

Upstream 100 bases:

>100_bases
ACTACTTCTACACGCCGGGCGTCATCGCCGAGGTGTGCGGCGAGCTCGGCCTCCCCTACCGCATCAACGGCTACCGCTAC
TGGTGAGAGGGATCCCGCCC

Downstream 100 bases:

>100_bases
CCGGGCCCGGACGCCGGCCGTGCCGGGATGGTGGACCGGATCGGTCCACGCACGATTCGCCGGCGTCCGCCCGCGGCACG
TTGTCGCGAAGCACATTCCG

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: Aminohydrolase [H]

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MTALLPAALAAALLAASPAAPNAPARAPADPVQRGYAPVNGLRIYYELHGPAGAKGPPLVLLHGGGSSIDTSFASLLPAL
ARHRRVIAFDQQGHGRTADLPDRPFTFEQSADDTAALLRHLGVARADLLGFSNGGTIALQVAVRHPALVRRLVVASAMVR
RDGLAPQAWEAIRRGRLEDMPVELRQAYLAVAPHPDQLASFHAKSARRMLEFRDWPDAEVRSITVPVLVVAGDRDAVLPE
HAVALTRMLPDARLAVLPATDHDGVVQRRVEWLGPMIEAFLDEP

Sequences:

>Translated_284_residues
MTALLPAALAAALLAASPAAPNAPARAPADPVQRGYAPVNGLRIYYELHGPAGAKGPPLVLLHGGGSSIDTSFASLLPAL
ARHRRVIAFDQQGHGRTADLPDRPFTFEQSADDTAALLRHLGVARADLLGFSNGGTIALQVAVRHPALVRRLVVASAMVR
RDGLAPQAWEAIRRGRLEDMPVELRQAYLAVAPHPDQLASFHAKSARRMLEFRDWPDAEVRSITVPVLVVAGDRDAVLPE
HAVALTRMLPDARLAVLPATDHDGVVQRRVEWLGPMIEAFLDEP
>Mature_283_residues
TALLPAALAAALLAASPAAPNAPARAPADPVQRGYAPVNGLRIYYELHGPAGAKGPPLVLLHGGGSSIDTSFASLLPALA
RHRRVIAFDQQGHGRTADLPDRPFTFEQSADDTAALLRHLGVARADLLGFSNGGTIALQVAVRHPALVRRLVVASAMVRR
DGLAPQAWEAIRRGRLEDMPVELRQAYLAVAPHPDQLASFHAKSARRMLEFRDWPDAEVRSITVPVLVVAGDRDAVLPEH
AVALTRMLPDARLAVLPATDHDGVVQRRVEWLGPMIEAFLDEP

Specific function: May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Hydrolase RutD family [H]

Homologues:

Organism=Homo sapiens, GI221316588, Length=255, Percent_Identity=26.6666666666667, Blast_Score=79, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR019913 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 30476; Mature: 30345

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALLPAALAAALLAASPAAPNAPARAPADPVQRGYAPVNGLRIYYELHGPAGAKGPPLV
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEEEECCCCCCCCCEE
LLHGGGSSIDTSFASLLPALARHRRVIAFDQQGHGRTADLPDRPFTFEQSADDTAALLRH
EEECCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
LGVARADLLGFSNGGTIALQVAVRHPALVRRLVVASAMVRRDGLAPQAWEAIRRGRLEDM
HCHHHHHHHCCCCCCEEEEEEEHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCC
PVELRQAYLAVAPHPDQLASFHAKSARRMLEFRDWPDAEVRSITVPVLVVAGDRDAVLPE
CHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCCCCCCHH
HAVALTRMLPDARLAVLPATDHDGVVQRRVEWLGPMIEAFLDEP
HHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TALLPAALAAALLAASPAAPNAPARAPADPVQRGYAPVNGLRIYYELHGPAGAKGPPLV
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEEEECCCCCCCCCEE
LLHGGGSSIDTSFASLLPALARHRRVIAFDQQGHGRTADLPDRPFTFEQSADDTAALLRH
EEECCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
LGVARADLLGFSNGGTIALQVAVRHPALVRRLVVASAMVRRDGLAPQAWEAIRRGRLEDM
HCHHHHHHHCCCCCCEEEEEEEHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCC
PVELRQAYLAVAPHPDQLASFHAKSARRMLEFRDWPDAEVRSITVPVLVVAGDRDAVLPE
CHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCCCCCCHH
HAVALTRMLPDARLAVLPATDHDGVVQRRVEWLGPMIEAFLDEP
HHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA