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The map label for this gene is alkR [H]

Identifier: 220916789

GI number: 220916789

Start: 1875651

End: 1876655

Strand: Direct

Name: alkR [H]

Synonym: A2cp1_1684

Alternate gene names: 220916789

Gene position: 1875651-1876655 (Clockwise)

Preceding gene: 220916785

Following gene: 220916790

Centisome position: 37.29

GC content: 78.11

Gene sequence:

>1005_bases
ATGGGCGCGGATCCGCTGGCCGACGTGCTGACCTCGGTTCGCCTGACCGGCTCGGTGTTCTTCCGCGTCGCGGGCGCTCC
GCCCTGGGCCGCCGAGGCGCCGCCCTCCCGCGCCATCGCGGCGCAGGTGATGCCCGGCGCCGACCACGTCATCGAGTTCC
ACGCGGTGGCGCGCGGGCGCTGCCTCGCAGGCATCGTGGGAGAGCCGCCGGTCGTGCTCGAGGCGGGGGACGTCGTCTGC
TTCCCGCACGGCGACGCGCACGTCCTGTCGAGCGCGGCCGGCCTCCGCGGCGCCGCGCCGGACCTCGCGCCGTACGCGCT
GGCGCGGGACGCGCCGCGGCCGTTCCTGGTGCGGGTCGGCGCCGGGCCCCCCGACACCGAGGTGCTGTGCGGCTTCTTCG
GATGCGACGCGCGCCCGTTCAACCCGCTGCTCGCCTCGCTGCCGCGCCTGCTCCGCGCCAGCGATCGGGAGGGACCGCGC
CGCGGGTGGCTGTCGCGGTTCCTCGAGGTGGCGGAGGCCGAGGCGAGCGCGCCGGGACCGGGAGGCGAGGGCGTGCTGAG
CCGGCTCGCGGAGCTGATGTTCCTCGAGATGGTGCGTCGGCACCTCGAGGCCCTCCCGGCGGGCCGCGGCGGCTGGCTGG
CGGGCCTCTCGGATCCGCACGTGGGCCGCGCGCTCGCGGCGCTCCACGCGCGCCCGGCGGATCCGTGGTCGCTGGAGCGG
CTCGCCCGCGCCGCCGGCCTGGCCCGCTCGTCCCTGGCGGAGCGGTTCGCGACGCTCATCGGCGAGCCGCCCATGCAGTA
CCTCGCGCGCTGGCGCATGCAGGTCGCGGCCGGGCTGCTCGCCACCACGCGCGAGGGCGTGGCGTCGATCGCGGGCCAGG
TGGGCTACGCCTCGGAGGCGGCGTTCAACCGGGCGTTCAAGAAGTGCGTGGGGGAGCCGCCCGCCACCTGGCGCCGCCGC
CGCGCCGACAGGAGGCCCGAACGACGCGCTGGGCCGGCCGCGTAG

Upstream 100 bases:

>100_bases
CGGGCCGGTCCGGACCTGCTCGCCCCGCCGCGTTCGTTGCCCGTCCGTCCGCGACCTGAGCGGGGCCCACGGGCCCACGG
AGCGTCACGGGGGAGGGCGA

Downstream 100 bases:

>100_bases
CCGCCGCTCCGTCCGCGCTGCGTCCGTCCCCGCCCGTGCCACGCGCGAGATTCCGCGCGTACCGGCGCGGCACGCCCGTG
GCATCTGCGCCCGTCCCCAC

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MGADPLADVLTSVRLTGSVFFRVAGAPPWAAEAPPSRAIAAQVMPGADHVIEFHAVARGRCLAGIVGEPPVVLEAGDVVC
FPHGDAHVLSSAAGLRGAAPDLAPYALARDAPRPFLVRVGAGPPDTEVLCGFFGCDARPFNPLLASLPRLLRASDREGPR
RGWLSRFLEVAEAEASAPGPGGEGVLSRLAELMFLEMVRRHLEALPAGRGGWLAGLSDPHVGRALAALHARPADPWSLER
LARAAGLARSSLAERFATLIGEPPMQYLARWRMQVAAGLLATTREGVASIAGQVGYASEAAFNRAFKKCVGEPPATWRRR
RADRRPERRAGPAA

Sequences:

>Translated_334_residues
MGADPLADVLTSVRLTGSVFFRVAGAPPWAAEAPPSRAIAAQVMPGADHVIEFHAVARGRCLAGIVGEPPVVLEAGDVVC
FPHGDAHVLSSAAGLRGAAPDLAPYALARDAPRPFLVRVGAGPPDTEVLCGFFGCDARPFNPLLASLPRLLRASDREGPR
RGWLSRFLEVAEAEASAPGPGGEGVLSRLAELMFLEMVRRHLEALPAGRGGWLAGLSDPHVGRALAALHARPADPWSLER
LARAAGLARSSLAERFATLIGEPPMQYLARWRMQVAAGLLATTREGVASIAGQVGYASEAAFNRAFKKCVGEPPATWRRR
RADRRPERRAGPAA
>Mature_333_residues
GADPLADVLTSVRLTGSVFFRVAGAPPWAAEAPPSRAIAAQVMPGADHVIEFHAVARGRCLAGIVGEPPVVLEAGDVVCF
PHGDAHVLSSAAGLRGAAPDLAPYALARDAPRPFLVRVGAGPPDTEVLCGFFGCDARPFNPLLASLPRLLRASDREGPRR
GWLSRFLEVAEAEASAPGPGGEGVLSRLAELMFLEMVRRHLEALPAGRGGWLAGLSDPHVGRALAALHARPADPWSLERL
ARAAGLARSSLAERFATLIGEPPMQYLARWRMQVAAGLLATTREGVASIAGQVGYASEAAFNRAFKKCVGEPPATWRRRR
ADRRPERRAGPAA

Specific function: This protein activates the expression of the alkane 1- monooxygenase AlkM [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786496, Length=278, Percent_Identity=26.2589928057554, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 35289; Mature: 35158

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGADPLADVLTSVRLTGSVFFRVAGAPPWAAEAPPSRAIAAQVMPGADHVIEFHAVARGR
CCCCHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCC
CLAGIVGEPPVVLEAGDVVCFPHGDAHVLSSAAGLRGAAPDLAPYALARDAPRPFLVRVG
HHCCCCCCCCEEEECCCEEEECCCCHHHHHHHHCCCCCCCCHHHHHHHCCCCCCEEEEEC
AGPPDTEVLCGFFGCDARPFNPLLASLPRLLRASDREGPRRGWLSRFLEVAEAEASAPGP
CCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCC
GGEGVLSRLAELMFLEMVRRHLEALPAGRGGWLAGLSDPHVGRALAALHARPADPWSLER
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHCCCCCCHHHHH
LARAAGLARSSLAERFATLIGEPPMQYLARWRMQVAAGLLATTREGVASIAGQVGYASEA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AFNRAFKKCVGEPPATWRRRRADRRPERRAGPAA
HHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
GADPLADVLTSVRLTGSVFFRVAGAPPWAAEAPPSRAIAAQVMPGADHVIEFHAVARGR
CCCHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCC
CLAGIVGEPPVVLEAGDVVCFPHGDAHVLSSAAGLRGAAPDLAPYALARDAPRPFLVRVG
HHCCCCCCCCEEEECCCEEEECCCCHHHHHHHHCCCCCCCCHHHHHHHCCCCCCEEEEEC
AGPPDTEVLCGFFGCDARPFNPLLASLPRLLRASDREGPRRGWLSRFLEVAEAEASAPGP
CCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCC
GGEGVLSRLAELMFLEMVRRHLEALPAGRGGWLAGLSDPHVGRALAALHARPADPWSLER
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHCCCCCCHHHHH
LARAAGLARSSLAERFATLIGEPPMQYLARWRMQVAAGLLATTREGVASIAGQVGYASEA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AFNRAFKKCVGEPPATWRRRRADRRPERRAGPAA
HHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9546151 [H]