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The map label for this gene is 220916786

Identifier: 220916786

GI number: 220916786

Start: 1872781

End: 1873761

Strand: Reverse

Name: 220916786

Synonym: A2cp1_1681

Alternate gene names: NA

Gene position: 1873761-1872781 (Counterclockwise)

Preceding gene: 220916787

Following gene: 220916768

Centisome position: 37.26

GC content: 76.25

Gene sequence:

>981_bases
GTGAGGATCGCGATCTACGGCGCCGGCGCGGTGGGCGGGCTCGTGGCCGCCCGCCTGGCGTGCGCCGGGCACGAGGTGAG
CGCGGTGGCGCGCGGCGCGACGCTCGACGCGCTGCGGTCGCGCGGGCTGCGGCTCGTCTCGGCCGGCGGGGAGGCGCGCG
TCCGGCTCCCGGCGTCGGACGATCCCGCCGAGCTCGGGCCGCAGGAGCTGGTGGTCGTGGCGGTGAAGGCGCCCGCGCTC
GTCCACGTGGCCCGGGACATCGGCCCGCTGCTCGGGCCGGACACGGTCGTGCTCACCGCCATGAACGGCGTGCCCTGGTG
GTTCTTCGACCGGTTCGGCGGCCGCTGGGCCGGCACCCGGCTCGACTCGGTGGACCCCGGCGGCGCCATCGCGGCGGGCA
TCCCGTCGCGGCACGTGGTCGGCTGCGTGGTCCACCTCGCCTGCGCGGTGCCGGAGCCGGGGTTCGTGTGCCACACGGCC
GGCAACCGCCTCATCGTGGGCGAGCCCGGCGGCGAGGCGTCGCAGCGCCTCGCGCGCCTCGCCGCGACGCTCCGCGGCGC
CGGGTTCGACGTGGACGTCTCGCGGCGGATCCAGGCGGACGTCTGGTACAAGCTCTGGGGCAACATGACCATGAACCCGG
TCTCGGCGATCACCGGCGCCACCTGCGACCGGATCCTCGACGATCCGCAGGTGTACCGCTTCTGCCTGGACGTCATGGGC
GAGGCGGCGCGCATCGGCGCGGCCATCGGGTGCCCCATCTCCGAGAGCGGCGAGGACCGCATGGCGGTCACGCGCAAGCT
GGGCGCGTTCAAGACGTCGATGCTGCAGGACGTGGAGGCGGGCCGGGCGGTGGAGCTGGACGCGCTCGTGTCGGCGGTGC
GGGAGATCGGCGCGCGGGTCGGCGAGCCGACGCCGCGCATCGACACGCTGCTCGGGCTGGCCCGGCTGCACGCGCGCGTG
CGCGGCCTCTACCCGGCCTGA

Upstream 100 bases:

>100_bases
ACGAGTGAACCCGGCCCGGCCGCGTCGCGCGGCGCGCCCCGCGCCCGCCCCGCCTGCGGTACTCTCCCCTCCGCGGAGGC
TCCGCGGGGAGGTGGTGGCG

Downstream 100 bases:

>100_bases
CCGGCGGCGCCGCCGGCGGCCGCCACGCCCTCCAGCACCTGGTCGATGGTCACGACGTCCACCAGGCCGCGCACCTGGTA
GAGCGCCGGGATGACCTGCT

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MRIAIYGAGAVGGLVAARLACAGHEVSAVARGATLDALRSRGLRLVSAGGEARVRLPASDDPAELGPQELVVVAVKAPAL
VHVARDIGPLLGPDTVVLTAMNGVPWWFFDRFGGRWAGTRLDSVDPGGAIAAGIPSRHVVGCVVHLACAVPEPGFVCHTA
GNRLIVGEPGGEASQRLARLAATLRGAGFDVDVSRRIQADVWYKLWGNMTMNPVSAITGATCDRILDDPQVYRFCLDVMG
EAARIGAAIGCPISESGEDRMAVTRKLGAFKTSMLQDVEAGRAVELDALVSAVREIGARVGEPTPRIDTLLGLARLHARV
RGLYPA

Sequences:

>Translated_326_residues
MRIAIYGAGAVGGLVAARLACAGHEVSAVARGATLDALRSRGLRLVSAGGEARVRLPASDDPAELGPQELVVVAVKAPAL
VHVARDIGPLLGPDTVVLTAMNGVPWWFFDRFGGRWAGTRLDSVDPGGAIAAGIPSRHVVGCVVHLACAVPEPGFVCHTA
GNRLIVGEPGGEASQRLARLAATLRGAGFDVDVSRRIQADVWYKLWGNMTMNPVSAITGATCDRILDDPQVYRFCLDVMG
EAARIGAAIGCPISESGEDRMAVTRKLGAFKTSMLQDVEAGRAVELDALVSAVREIGARVGEPTPRIDTLLGLARLHARV
RGLYPA
>Mature_326_residues
MRIAIYGAGAVGGLVAARLACAGHEVSAVARGATLDALRSRGLRLVSAGGEARVRLPASDDPAELGPQELVVVAVKAPAL
VHVARDIGPLLGPDTVVLTAMNGVPWWFFDRFGGRWAGTRLDSVDPGGAIAAGIPSRHVVGCVVHLACAVPEPGFVCHTA
GNRLIVGEPGGEASQRLARLAATLRGAGFDVDVSRRIQADVWYKLWGNMTMNPVSAITGATCDRILDDPQVYRFCLDVMG
EAARIGAAIGCPISESGEDRMAVTRKLGAFKTSMLQDVEAGRAVELDALVSAVREIGARVGEPTPRIDTLLGLARLHARV
RGLYPA

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 34105; Mature: 34105

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIAIYGAGAVGGLVAARLACAGHEVSAVARGATLDALRSRGLRLVSAGGEARVRLPASD
CEEEEEECCHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHCCEEEEECCCCEEEECCCCC
DPAELGPQELVVVAVKAPALVHVARDIGPLLGPDTVVLTAMNGVPWWFFDRFGGRWAGTR
CHHHCCCCCEEEEEECCCHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHCCCCCCCCC
LDSVDPGGAIAAGIPSRHVVGCVVHLACAVPEPGFVCHTAGNRLIVGEPGGEASQRLARL
CCCCCCCCCEECCCCCHHHHHHHHHHHHCCCCCCEEEECCCCEEEEECCCCHHHHHHHHH
AATLRGAGFDVDVSRRIQADVWYKLWGNMTMNPVSAITGATCDRILDDPQVYRFCLDVMG
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHCCCHHHHHHHHHHHH
EAARIGAAIGCPISESGEDRMAVTRKLGAFKTSMLQDVEAGRAVELDALVSAVREIGARV
HHHHHCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHC
GEPTPRIDTLLGLARLHARVRGLYPA
CCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRIAIYGAGAVGGLVAARLACAGHEVSAVARGATLDALRSRGLRLVSAGGEARVRLPASD
CEEEEEECCHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHCCEEEEECCCCEEEECCCCC
DPAELGPQELVVVAVKAPALVHVARDIGPLLGPDTVVLTAMNGVPWWFFDRFGGRWAGTR
CHHHCCCCCEEEEEECCCHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHCCCCCCCCC
LDSVDPGGAIAAGIPSRHVVGCVVHLACAVPEPGFVCHTAGNRLIVGEPGGEASQRLARL
CCCCCCCCCEECCCCCHHHHHHHHHHHHCCCCCCEEEECCCCEEEEECCCCHHHHHHHHH
AATLRGAGFDVDVSRRIQADVWYKLWGNMTMNPVSAITGATCDRILDDPQVYRFCLDVMG
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHCCCHHHHHHHHHHHH
EAARIGAAIGCPISESGEDRMAVTRKLGAFKTSMLQDVEAGRAVELDALVSAVREIGARV
HHHHHCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHC
GEPTPRIDTLLGLARLHARVRGLYPA
CCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]