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The map label for this gene is glpG [H]

Identifier: 220916741

GI number: 220916741

Start: 1826607

End: 1827563

Strand: Reverse

Name: glpG [H]

Synonym: A2cp1_1635

Alternate gene names: 220916741

Gene position: 1827563-1826607 (Counterclockwise)

Preceding gene: 220916742

Following gene: 220916740

Centisome position: 36.34

GC content: 69.49

Gene sequence:

>957_bases
ATGAGACAGGACGCTCCCGAAGCCCTCTCTCCGGTCGCCGGGAGCACCTCGCGTCCAGCACTTGCGACGGGGCCGGCCTC
GAGACGCCGAGTGCCGTGGGTCACGGCCACCGCCTGCGCCACGATGGTGGCACTCTTCGCGGTGATCTCCGCAACGCCAG
GCGAGGCGCCGTTCGCGTCCTGGGGCTACCGTGGCGACGCGTTCCAGGTCTGGTCCGGGGCGGCCTGGGTGCTGCTCGTT
TCAGCCTTCATCCACCAGGCCCTGTCGCACCTGGCGCTGAACGTCTACTGGCTGTGGACGCTCGGGCGGGCGGTCGAGGG
CGCATTCGGACCGCGCGCGATGGGGCTGCTCCTGCTCACGTCCGCGTTCGTGAGCTCTTCGTTCCATCTGGCCATCTTCG
ACGACGTCGGAGTGGGCGCTTCCGGAATGGTGTTCGCCGTGTTCGGCTTCGGATGGCTGGCGAGGGGCAAGCGCGGCGAG
CTGAGAGCGACTTTCACGACGAAGACCGGAATCCTGTTCGCGGCAGGTCTCGTCGGATGCTGGATCGTCCTGACACGCGA
GGTGGCGAACGGGGCTCACCTCGGCGGCCTCCTGTTCGGAGCAGCCGCCGCGGAGGCCGTCGCGACGGGGAGGCGGCCAC
GCCTGGCGAAGGCCGGAGCGATCCTCCTGATCCTGCTGGCGTTTGGCGTCACCGTCGCCTGCCCGTGGTCAGCCACCTGG
TGGTCCACCAAGGGTCACGGCGCTCATGCCCGCGGCCAGTACGACCTTGCCATCCAGGCGTATGACATGAGCCTCCGGTT
CCGGCCCGACCAGCCGTGGGTCATGGCGAGCCTGATTCGCGCCTACCGCGCCTCGGGGAACGCGGACGCCGCGGCCTCGC
TCCTCACGAGGCTGAGGACCGTCTCGCCCGCCGAAGCAGCGCTGATCGACGAGGAAGGCCGATCGCCGGTCAAGTGA

Upstream 100 bases:

>100_bases
ACTCGAGGTGACCGGCGGAGACGATTGCGGTTCCTGGGTGCCACATATACTCTCCGTGGCGGCCAATCCATTGGCGTGAG
GCCGGCAGGGGGCCAACGAC

Downstream 100 bases:

>100_bases
TCCGGGACCGGCCGCCGATCGTCCCGCGCTCGCCAGGCAACTCGGTGCCGAGCCGGATGTGACGGCCAAAGGGCTTGACG
GACTTCACTGTCGGCGCAAG

Product: Rhomboid family protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MRQDAPEALSPVAGSTSRPALATGPASRRRVPWVTATACATMVALFAVISATPGEAPFASWGYRGDAFQVWSGAAWVLLV
SAFIHQALSHLALNVYWLWTLGRAVEGAFGPRAMGLLLLTSAFVSSSFHLAIFDDVGVGASGMVFAVFGFGWLARGKRGE
LRATFTTKTGILFAAGLVGCWIVLTREVANGAHLGGLLFGAAAAEAVATGRRPRLAKAGAILLILLAFGVTVACPWSATW
WSTKGHGAHARGQYDLAIQAYDMSLRFRPDQPWVMASLIRAYRASGNADAAASLLTRLRTVSPAEAALIDEEGRSPVK

Sequences:

>Translated_318_residues
MRQDAPEALSPVAGSTSRPALATGPASRRRVPWVTATACATMVALFAVISATPGEAPFASWGYRGDAFQVWSGAAWVLLV
SAFIHQALSHLALNVYWLWTLGRAVEGAFGPRAMGLLLLTSAFVSSSFHLAIFDDVGVGASGMVFAVFGFGWLARGKRGE
LRATFTTKTGILFAAGLVGCWIVLTREVANGAHLGGLLFGAAAAEAVATGRRPRLAKAGAILLILLAFGVTVACPWSATW
WSTKGHGAHARGQYDLAIQAYDMSLRFRPDQPWVMASLIRAYRASGNADAAASLLTRLRTVSPAEAALIDEEGRSPVK
>Mature_318_residues
MRQDAPEALSPVAGSTSRPALATGPASRRRVPWVTATACATMVALFAVISATPGEAPFASWGYRGDAFQVWSGAAWVLLV
SAFIHQALSHLALNVYWLWTLGRAVEGAFGPRAMGLLLLTSAFVSSSFHLAIFDDVGVGASGMVFAVFGFGWLARGKRGE
LRATFTTKTGILFAAGLVGCWIVLTREVANGAHLGGLLFGAAAAEAVATGRRPRLAKAGAILLILLAFGVTVACPWSATW
WSTKGHGAHARGQYDLAIQAYDMSLRFRPDQPWVMASLIRAYRASGNADAAASLLTRLRTVSPAEAALIDEEGRSPVK

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S54 family [H]

Homologues:

Organism=Escherichia coli, GI48994938, Length=141, Percent_Identity=33.3333333333333, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022732
- InterPro:   IPR002610
- InterPro:   IPR022764 [H]

Pfam domain/function: PF12122 DUF3582; PF01694 Rhomboid [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 33572; Mature: 33572

Theoretical pI: Translated: 10.60; Mature: 10.60

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQDAPEALSPVAGSTSRPALATGPASRRRVPWVTATACATMVALFAVISATPGEAPFAS
CCCCCCHHHCCCCCCCCCCCEECCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCC
WGYRGDAFQVWSGAAWVLLVSAFIHQALSHLALNVYWLWTLGRAVEGAFGPRAMGLLLLT
CCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHCCCCHHHHHHHHHH
SAFVSSSFHLAIFDDVGVGASGMVFAVFGFGWLARGKRGELRATFTTKTGILFAAGLVGC
HHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHH
WIVLTREVANGAHLGGLLFGAAAAEAVATGRRPRLAKAGAILLILLAFGVTVACPWSATW
HHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCC
WSTKGHGAHARGQYDLAIQAYDMSLRFRPDQPWVMASLIRAYRASGNADAAASLLTRLRT
CCCCCCCCCCCCCEEEEEEEEEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHC
VSPAEAALIDEEGRSPVK
CCCHHHHEECCCCCCCCC
>Mature Secondary Structure
MRQDAPEALSPVAGSTSRPALATGPASRRRVPWVTATACATMVALFAVISATPGEAPFAS
CCCCCCHHHCCCCCCCCCCCEECCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCC
WGYRGDAFQVWSGAAWVLLVSAFIHQALSHLALNVYWLWTLGRAVEGAFGPRAMGLLLLT
CCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHCCCCHHHHHHHHHH
SAFVSSSFHLAIFDDVGVGASGMVFAVFGFGWLARGKRGELRATFTTKTGILFAAGLVGC
HHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHH
WIVLTREVANGAHLGGLLFGAAAAEAVATGRRPRLAKAGAILLILLAFGVTVACPWSATW
HHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCC
WSTKGHGAHARGQYDLAIQAYDMSLRFRPDQPWVMASLIRAYRASGNADAAASLLTRLRT
CCCCCCCCCCCCCEEEEEEEEEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHC
VSPAEAALIDEEGRSPVK
CCCHHHHEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA