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The map label for this gene is trg [H]

Identifier: 220916428

GI number: 220916428

Start: 1468516

End: 1470132

Strand: Direct

Name: trg [H]

Synonym: A2cp1_1322

Alternate gene names: 220916428

Gene position: 1468516-1470132 (Clockwise)

Preceding gene: 220916427

Following gene: 220916430

Centisome position: 29.2

GC content: 73.78

Gene sequence:

>1617_bases
ATGCTCGCCAACCTCAGGATCCGCACCAAGCTCGCCCTCCTCGTGGTCGTGGGCTCCCTCGCCCTCCTCGCCGTGGCCTC
CGCCGCGCTGATGCAGGGGCGCGCGAGCGACGCCACCATCGCCCGCATGGCCGGCAGCGACCTCGAGCTCCTGGTCGGCT
TCGAGTCCATGTACTCGGCGGGCCTGCAGACCGGGCAGGCGACCCGCAACGTCCTGCTCGACCCCCAGGACCGCACGGCG
AAGAAGAACTACCGGGACGCGCACGAGGCGTTCTCGACGACCCTCGAGCAAGCGCGGAAGCTCGCGCCTCCCGAGCTGAA
GTCGCGGCTGCAGGAGGTGGACCGCCTCTGGGCCGCGGACCACGTGCTCAAGCAGGAGGTGATGAGCCTCTCCGAGGCCG
GCCGCCGCGACGAGGCGGTCGCGGTCCTCGTCAGCAAGGAGACCCCGGTGTGGCGCGCGGTGAAGCAGGTCATCCTCGAG
CTCCGCGACGAGCAGCGGCGCGCCTTCTCGAGGAGCGAGGCGTCCGCCCTCCGCGACACGGCCCTCGTCAGGCGGGTGGT
GCTCGGCACGATCGTGGTGGCCGCCGCGGTCTTCGTGCTCCTCTCCGTGGTCCTCGCGCGGAGCATCACCGCTCCGCTCC
GGGAGGCGATCCGGGTCGCGGCGGCGATCTCGCGCGGCGATCTGACCGCGACCGTCGCGGCGGGACGTCGCGACGAGGTC
GGTCGGCTCCAGGCGGAGCTGGGCGCGATGGCGCAGAAGCTGGCGCAGGTGATCGGCGAGGTCCGGAGCGGCGCCGAGGC
GCTCGCCGGCGCCTCGCAGCAGGTCTCGGCGACGTCCCAGGCCCTGTCGCAGGGCACCGGCGAGCAGGCCAGCAGCGTGG
AGGAGACGACCGCTTCGCTCGAGCAGATGAGCGCGTCGATCGAGCAGAACGCGGAGAGCTCCCGCGCGACGGAGGCCGCC
TCGAAGGAGAGCGCCGCGAACGCGGAGGAGGGCGGGAAGTCGGTCCGGCAGACCGTCGCCGCGATGAAGGCGATCGTGGA
GAAGATCTCGATCATCGAGGAGATCGCCTACCAGACGAACCTGCTCGCGCTGAACGCGGCGATCGAGGCCGCGCGGGCGG
GAGCGCACGGCCGCGGGTTCGCGGTGGTGGCGGCAGAGGTCCGGAAGCTCGCCGAGCGCTCGCAGAAGGCTGCGCAGGAC
ATCGGCGGGCTGGCCGGCTCGAGCGTCGCGGCCGCCGAGCGCTCGGGCGAGCTCATCGAGCGGCTCGTGCCCGCGATCCG
CAGGACGGCGGCGCTGGTCCACGAGGTGGCGGCGGCGTCCCAGGAGCAGTCCTCCGGCGTCGGCCAGGTCTCGAAGGCGA
TGGCGCTCGTCGATCAGGTCACCCAGCGGACCGCGTCCGCGGCCGAGGAGCTCAGCGCCACCGCAGAGGAGATGGCCTCG
CAGGCGGAGGGGCTGCAGCAGCTCATCTCGTTCTTCCACCTGGAGGGCCAGGGCGCTCGCGTCGCGCGCACCGCGCAGCC
GCCGCACGCGGCGGGGGCGTTCGCGCGCCCCCAGGACGCGGGCCTGGCGGGGGTCGCCGGCGGCAAGGCCGGGAGCGCGG
GAGTCCGGCCGAGCTAG

Upstream 100 bases:

>100_bases
GCGCTCCGGTGGCCGAGTTGGGGCATCGACACGCTTCCTGCATGAGGCCACGCGCGGGGGCCGGTGGACCGCACGACGAG
GCTCCTCACGGGATACCGAC

Downstream 100 bases:

>100_bases
CGATCCGGAGGACCTCGACGAGGCGCTCGCGGGCGCCTCCGGAGGGAAGCGCGCGGTCGAAGCTGCGTGCGGAGGCGGGT
GGGAAGCCCCGGGCGCAGGG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: MCP-III; Ribose and galactose chemoreceptor protein [H]

Number of amino acids: Translated: 538; Mature: 538

Protein sequence:

>538_residues
MLANLRIRTKLALLVVVGSLALLAVASAALMQGRASDATIARMAGSDLELLVGFESMYSAGLQTGQATRNVLLDPQDRTA
KKNYRDAHEAFSTTLEQARKLAPPELKSRLQEVDRLWAADHVLKQEVMSLSEAGRRDEAVAVLVSKETPVWRAVKQVILE
LRDEQRRAFSRSEASALRDTALVRRVVLGTIVVAAAVFVLLSVVLARSITAPLREAIRVAAAISRGDLTATVAAGRRDEV
GRLQAELGAMAQKLAQVIGEVRSGAEALAGASQQVSATSQALSQGTGEQASSVEETTASLEQMSASIEQNAESSRATEAA
SKESAANAEEGGKSVRQTVAAMKAIVEKISIIEEIAYQTNLLALNAAIEAARAGAHGRGFAVVAAEVRKLAERSQKAAQD
IGGLAGSSVAAAERSGELIERLVPAIRRTAALVHEVAAASQEQSSGVGQVSKAMALVDQVTQRTASAAEELSATAEEMAS
QAEGLQQLISFFHLEGQGARVARTAQPPHAAGAFARPQDAGLAGVAGGKAGSAGVRPS

Sequences:

>Translated_538_residues
MLANLRIRTKLALLVVVGSLALLAVASAALMQGRASDATIARMAGSDLELLVGFESMYSAGLQTGQATRNVLLDPQDRTA
KKNYRDAHEAFSTTLEQARKLAPPELKSRLQEVDRLWAADHVLKQEVMSLSEAGRRDEAVAVLVSKETPVWRAVKQVILE
LRDEQRRAFSRSEASALRDTALVRRVVLGTIVVAAAVFVLLSVVLARSITAPLREAIRVAAAISRGDLTATVAAGRRDEV
GRLQAELGAMAQKLAQVIGEVRSGAEALAGASQQVSATSQALSQGTGEQASSVEETTASLEQMSASIEQNAESSRATEAA
SKESAANAEEGGKSVRQTVAAMKAIVEKISIIEEIAYQTNLLALNAAIEAARAGAHGRGFAVVAAEVRKLAERSQKAAQD
IGGLAGSSVAAAERSGELIERLVPAIRRTAALVHEVAAASQEQSSGVGQVSKAMALVDQVTQRTASAAEELSATAEEMAS
QAEGLQQLISFFHLEGQGARVARTAQPPHAAGAFARPQDAGLAGVAGGKAGSAGVRPS
>Mature_538_residues
MLANLRIRTKLALLVVVGSLALLAVASAALMQGRASDATIARMAGSDLELLVGFESMYSAGLQTGQATRNVLLDPQDRTA
KKNYRDAHEAFSTTLEQARKLAPPELKSRLQEVDRLWAADHVLKQEVMSLSEAGRRDEAVAVLVSKETPVWRAVKQVILE
LRDEQRRAFSRSEASALRDTALVRRVVLGTIVVAAAVFVLLSVVLARSITAPLREAIRVAAAISRGDLTATVAAGRRDEV
GRLQAELGAMAQKLAQVIGEVRSGAEALAGASQQVSATSQALSQGTGEQASSVEETTASLEQMSASIEQNAESSRATEAA
SKESAANAEEGGKSVRQTVAAMKAIVEKISIIEEIAYQTNLLALNAAIEAARAGAHGRGFAVVAAEVRKLAERSQKAAQD
IGGLAGSSVAAAERSGELIERLVPAIRRTAALVHEVAAASQEQSSGVGQVSKAMALVDQVTQRTASAAEELSATAEEMAS
QAEGLQQLISFFHLEGQGARVARTAQPPHAAGAFARPQDAGLAGVAGGKAGSAGVRPS

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=324, Percent_Identity=39.5061728395062, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI2367378, Length=543, Percent_Identity=30.5709023941068, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1788195, Length=302, Percent_Identity=39.7350993377483, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1788194, Length=325, Percent_Identity=36.3076923076923, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1789453, Length=325, Percent_Identity=29.8461538461538, Blast_Score=142, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 56121; Mature: 56121

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLANLRIRTKLALLVVVGSLALLAVASAALMQGRASDATIARMAGSDLELLVGFESMYSA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHH
GLQTGQATRNVLLDPQDRTAKKNYRDAHEAFSTTLEQARKLAPPELKSRLQEVDRLWAAD
HCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
HVLKQEVMSLSEAGRRDEAVAVLVSKETPVWRAVKQVILELRDEQRRAFSRSEASALRDT
HHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALVRRVVLGTIVVAAAVFVLLSVVLARSITAPLREAIRVAAAISRGDLTATVAAGRRDEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHH
GRLQAELGAMAQKLAQVIGEVRSGAEALAGASQQVSATSQALSQGTGEQASSVEETTASL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
EQMSASIEQNAESSRATEAASKESAANAEEGGKSVRQTVAAMKAIVEKISIIEEIAYQTN
HHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLALNAAIEAARAGAHGRGFAVVAAEVRKLAERSQKAAQDIGGLAGSSVAAAERSGELIE
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
RLVPAIRRTAALVHEVAAASQEQSSGVGQVSKAMALVDQVTQRTASAAEELSATAEEMAS
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAEGLQQLISFFHLEGQGARVARTAQPPHAAGAFARPQDAGLAGVAGGKAGSAGVRPS
HHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLANLRIRTKLALLVVVGSLALLAVASAALMQGRASDATIARMAGSDLELLVGFESMYSA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHH
GLQTGQATRNVLLDPQDRTAKKNYRDAHEAFSTTLEQARKLAPPELKSRLQEVDRLWAAD
HCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
HVLKQEVMSLSEAGRRDEAVAVLVSKETPVWRAVKQVILELRDEQRRAFSRSEASALRDT
HHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALVRRVVLGTIVVAAAVFVLLSVVLARSITAPLREAIRVAAAISRGDLTATVAAGRRDEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHH
GRLQAELGAMAQKLAQVIGEVRSGAEALAGASQQVSATSQALSQGTGEQASSVEETTASL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
EQMSASIEQNAESSRATEAASKESAANAEEGGKSVRQTVAAMKAIVEKISIIEEIAYQTN
HHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLALNAAIEAARAGAHGRGFAVVAAEVRKLAERSQKAAQDIGGLAGSSVAAAERSGELIE
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
RLVPAIRRTAALVHEVAAASQEQSSGVGQVSKAMALVDQVTQRTASAAEELSATAEEMAS
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAEGLQQLISFFHLEGQGARVARTAQPPHAAGAFARPQDAGLAGVAGGKAGSAGVRPS
HHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6374654; 9097039; 9278503 [H]