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The map label for this gene is yciA [C]

Identifier: 220916375

GI number: 220916375

Start: 1423365

End: 1423844

Strand: Direct

Name: yciA [C]

Synonym: A2cp1_1269

Alternate gene names: 220916375

Gene position: 1423365-1423844 (Clockwise)

Preceding gene: 220916370

Following gene: 220916376

Centisome position: 28.3

GC content: 73.75

Gene sequence:

>480_bases
ATGCCCGCTCCCAAGCCCGCCGCCGACTCGCGCGTCGAGGTCACGCACCTGGTGATGCCGTTCGACGCGAACACGCTCGG
GACCGCGTTCGGCGGCACGGTCATGCAGTGGACCGACCTGACCGCGGCCATGGCCGCGATGCGCCACGCGCGCGTCCCGG
TCGTGACGGCCTCCATCGATCAGCTCTCCTTCCTCGCCCCCATCCGCATCGGCCAGATGGCCATCCTGCACGGGCAGGTG
AACGCGGTGTTCGGGTCCTCCATGGAGGTCGGCGTGGAGGTGCAGACCGAGGACCCGCTCACCGGCGAGCGGAAGAAGTG
CTGCGACGCGTATCTGACCTTCGTGGCGCTGGGGCCGGACGGGCAGCCCACCCGGGCCCCGCCCCTGCGGACCGACACCG
ACGACGAGCGCCGGCGCGAGCGCGAGGCGGGAGAGCGCCGCGCCGCGCGGCTGGCGTCCCGGACGCCGCGCGCACCGTGA

Upstream 100 bases:

>100_bases
ACCTCGAGCGGCATGGATCGGCTCCGGGGAAGGGCGCGCATCTTACGACGAACCCACGACAGCGCGGGAGGGGCGCCGCG
GCCCGTGCTAAGGGTGGCGC

Downstream 100 bases:

>100_bases
ACACGGGGCCGCGTTTCGCTTGAGGGGCCGCGCGCGCGGGGCCATATTGCCGCGGCCGGGCGGCGTCCGCCGCCCCGCCC
GCCCCGGAGGCCGACGTGCG

Product: thioesterase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MPAPKPAADSRVEVTHLVMPFDANTLGTAFGGTVMQWTDLTAAMAAMRHARVPVVTASIDQLSFLAPIRIGQMAILHGQV
NAVFGSSMEVGVEVQTEDPLTGERKKCCDAYLTFVALGPDGQPTRAPPLRTDTDDERRREREAGERRAARLASRTPRAP

Sequences:

>Translated_159_residues
MPAPKPAADSRVEVTHLVMPFDANTLGTAFGGTVMQWTDLTAAMAAMRHARVPVVTASIDQLSFLAPIRIGQMAILHGQV
NAVFGSSMEVGVEVQTEDPLTGERKKCCDAYLTFVALGPDGQPTRAPPLRTDTDDERRREREAGERRAARLASRTPRAP
>Mature_158_residues
PAPKPAADSRVEVTHLVMPFDANTLGTAFGGTVMQWTDLTAAMAAMRHARVPVVTASIDQLSFLAPIRIGQMAILHGQVN
AVFGSSMEVGVEVQTEDPLTGERKKCCDAYLTFVALGPDGQPTRAPPLRTDTDDERRREREAGERRAARLASRTPRAP

Specific function: Unknown

COG id: COG1607

COG function: function code I; Acyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl coenzyme A hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI22165400, Length=147, Percent_Identity=38.0952380952381, Blast_Score=95, Evalue=3e-20,
Organism=Homo sapiens, GI22165355, Length=147, Percent_Identity=38.0952380952381, Blast_Score=95, Evalue=3e-20,
Organism=Homo sapiens, GI18640736, Length=151, Percent_Identity=33.112582781457, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI32528286, Length=160, Percent_Identity=31.875, Blast_Score=84, Evalue=4e-17,
Organism=Homo sapiens, GI32528284, Length=160, Percent_Identity=31.875, Blast_Score=84, Evalue=4e-17,
Organism=Homo sapiens, GI75709208, Length=160, Percent_Identity=31.875, Blast_Score=84, Evalue=5e-17,
Organism=Homo sapiens, GI32528282, Length=160, Percent_Identity=31.875, Blast_Score=84, Evalue=6e-17,
Organism=Escherichia coli, GI1787506, Length=117, Percent_Identity=31.6239316239316, Blast_Score=61, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006683 [H]

Pfam domain/function: PF03061 4HBT [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 17211; Mature: 17080

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAPKPAADSRVEVTHLVMPFDANTLGTAFGGTVMQWTDLTAAMAAMRHARVPVVTASID
CCCCCCCCCCCEEEEEEEEECCCCCCCHHHCCCEEHHHHHHHHHHHHHHCCCCEEEECHH
QLSFLAPIRIGQMAILHGQVNAVFGSSMEVGVEVQTEDPLTGERKKCCDAYLTFVALGPD
HHHHHCCCCCCCEEEEECCHHEEECCCEEEEEEEECCCCCCCCHHHHHHHHEEEEEECCC
GQPTRAPPLRTDTDDERRREREAGERRAARLASRTPRAP
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PAPKPAADSRVEVTHLVMPFDANTLGTAFGGTVMQWTDLTAAMAAMRHARVPVVTASID
CCCCCCCCCCEEEEEEEEECCCCCCCHHHCCCEEHHHHHHHHHHHHHHCCCCEEEECHH
QLSFLAPIRIGQMAILHGQVNAVFGSSMEVGVEVQTEDPLTGERKKCCDAYLTFVALGPD
HHHHHCCCCCCCEEEEECCHHEEECCCEEEEEEEECCCCCCCCHHHHHHHHEEEEEECCC
GQPTRAPPLRTDTDDERRREREAGERRAARLASRTPRAP
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]