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The map label for this gene is otsB [H]

Identifier: 220916326

GI number: 220916326

Start: 1370493

End: 1371281

Strand: Direct

Name: otsB [H]

Synonym: A2cp1_1220

Alternate gene names: 220916326

Gene position: 1370493-1371281 (Clockwise)

Preceding gene: 220916324

Following gene: 220916327

Centisome position: 27.25

GC content: 76.3

Gene sequence:

>789_bases
ATGAAGGATCTCCTCCACCCCCGCCACCGCGCCGCGCTCGACCGCTTCCTCGGCGAGGGGGCGCGCCGCCCCGTCCTGCT
CGCCTTCGACTACGACGGCGTCCTCGCCCCCATCGTCAAGGATCCCGCCGGCGCCCGCATGCGCCCCTCCACCCGCACGC
TCCTGGCGCGGGTGGCCGGGCTGTACCCGGTGGCGGTGGTCTCCGGTCGCGCCTGGCGCGACACCCACCGGTTCGTGGGC
GACGTCGTCCCGACGGTGGTCGGCAACCACGGGTTCGAGCTCGGGCACCCGGTCCCGGTCCCGGCCCGCGTGCTGCGGAC
GGTGCGCGGCTGGCGGCGGCAGCTCGAGGCGGCGCTGGAGGGGGTGCCGGGCGTCCACTTCGAGGACAAGCGCTCCACGC
TCGCCATCCACTACGGGCTCACGCGTTCCTGGCGCCGCTCCGAGCACGCGGTGTACGAGGCCGCCAACCAGCTCGCCGGC
ACCCGGCTCATCCCGGGCAAGAAGGTGCTGAACGTGCTCCCGCACGACTTCCCGTCGAAGGGCGACGCGGTGCGCGCGCT
GCTCGCGCGGCTCGGCTGCGACGCGGCGCTCTACGCCGGCGACGACGTCACCGACGAGGACGCGTTCGCGGTGGGCGAGC
CGCTCGTGTTCGGCGTGCACGTGGGCAGCGGGCGCACGCTCGCGCCCTGGTGCCTGCGCGCGCAGGAGGACGTGGACGCG
TTGCTGGAGCGGCTGGTGGAGGCGCGCGCCGGGGCACGGCCGAGGCGCGCGGCGGGGCGGGCGCGGTGA

Upstream 100 bases:

>100_bases
GCACGCGCCGATTGTACGTGCCTTCCCCGGCGAGACGAAGATCCCCGGCCGCACCGCGCGGGCCGACGCGCGGGAATGCT
AGACTCCACGGCCCCGCGCC

Downstream 100 bases:

>100_bases
GCCGGCCGAAGCCCCCCGGCGCCGGCGCCACCGGCGACCTGTTCGCGCGCGCCGCCGAGCGGGCCGCCGCGGAGCGCGTC
CGCGCGGAGCCTCCCGCCGC

Product: HAD superfamily hydrolase

Products: NA

Alternate protein names: TPP; Trehalose-6-phosphate phosphatase [H]

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MKDLLHPRHRAALDRFLGEGARRPVLLAFDYDGVLAPIVKDPAGARMRPSTRTLLARVAGLYPVAVVSGRAWRDTHRFVG
DVVPTVVGNHGFELGHPVPVPARVLRTVRGWRRQLEAALEGVPGVHFEDKRSTLAIHYGLTRSWRRSEHAVYEAANQLAG
TRLIPGKKVLNVLPHDFPSKGDAVRALLARLGCDAALYAGDDVTDEDAFAVGEPLVFGVHVGSGRTLAPWCLRAQEDVDA
LLERLVEARAGARPRRAAGRAR

Sequences:

>Translated_262_residues
MKDLLHPRHRAALDRFLGEGARRPVLLAFDYDGVLAPIVKDPAGARMRPSTRTLLARVAGLYPVAVVSGRAWRDTHRFVG
DVVPTVVGNHGFELGHPVPVPARVLRTVRGWRRQLEAALEGVPGVHFEDKRSTLAIHYGLTRSWRRSEHAVYEAANQLAG
TRLIPGKKVLNVLPHDFPSKGDAVRALLARLGCDAALYAGDDVTDEDAFAVGEPLVFGVHVGSGRTLAPWCLRAQEDVDA
LLERLVEARAGARPRRAAGRAR
>Mature_262_residues
MKDLLHPRHRAALDRFLGEGARRPVLLAFDYDGVLAPIVKDPAGARMRPSTRTLLARVAGLYPVAVVSGRAWRDTHRFVG
DVVPTVVGNHGFELGHPVPVPARVLRTVRGWRRQLEAALEGVPGVHFEDKRSTLAIHYGLTRSWRRSEHAVYEAANQLAG
TRLIPGKKVLNVLPHDFPSKGDAVRALLARLGCDAALYAGDDVTDEDAFAVGEPLVFGVHVGSGRTLAPWCLRAQEDVDA
LLERLVEARAGARPRRAAGRAR

Specific function: Removes the phosphate from trehalose 6-phosphate to produce free trehalose [H]

COG id: COG1877

COG function: function code G; Trehalose-6-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trehalose phosphatase family [H]

Homologues:

Organism=Drosophila melanogaster, GI221473368, Length=213, Percent_Identity=30.0469483568075, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI20129307, Length=213, Percent_Identity=30.0469483568075, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24582490, Length=213, Percent_Identity=30.0469483568075, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19920676, Length=215, Percent_Identity=30.6976744186047, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006379
- InterPro:   IPR003337 [H]

Pfam domain/function: PF02358 Trehalose_PPase [H]

EC number: =3.1.3.12 [H]

Molecular weight: Translated: 28618; Mature: 28618

Theoretical pI: Translated: 10.68; Mature: 10.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDLLHPRHRAALDRFLGEGARRPVLLAFDYDGVLAPIVKDPAGARMRPSTRTLLARVAG
CCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCEEHHHHCCCCCCCCCCHHHHHHHHHHH
LYPVAVVSGRAWRDTHRFVGDVVPTVVGNHGFELGHPVPVPARVLRTVRGWRRQLEAALE
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GVPGVHFEDKRSTLAIHYGLTRSWRRSEHAVYEAANQLAGTRLIPGKKVLNVLPHDFPSK
CCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCC
GDAVRALLARLGCDAALYAGDDVTDEDAFAVGEPLVFGVHVGSGRTLAPWCLRAQEDVDA
CHHHHHHHHHHCCCEEEECCCCCCCCCCHHCCCCEEEEEEECCCCCHHHHHHCCHHHHHH
LLERLVEARAGARPRRAAGRAR
HHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKDLLHPRHRAALDRFLGEGARRPVLLAFDYDGVLAPIVKDPAGARMRPSTRTLLARVAG
CCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCEEHHHHCCCCCCCCCCHHHHHHHHHHH
LYPVAVVSGRAWRDTHRFVGDVVPTVVGNHGFELGHPVPVPARVLRTVRGWRRQLEAALE
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GVPGVHFEDKRSTLAIHYGLTRSWRRSEHAVYEAANQLAGTRLIPGKKVLNVLPHDFPSK
CCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCC
GDAVRALLARLGCDAALYAGDDVTDEDAFAVGEPLVFGVHVGSGRTLAPWCLRAQEDVDA
CHHHHHHHHHHCCCEEEECCCCCCCCCCHHCCCCEEEEEEECCCCCHHHHHHCCHHHHHH
LLERLVEARAGARPRRAAGRAR
HHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]