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The map label for this gene is virB11 [H]

Identifier: 220916252

GI number: 220916252

Start: 1276982

End: 1278049

Strand: Direct

Name: virB11 [H]

Synonym: A2cp1_1145

Alternate gene names: 220916252

Gene position: 1276982-1278049 (Clockwise)

Preceding gene: 220916251

Following gene: 220916253

Centisome position: 25.39

GC content: 71.82

Gene sequence:

>1068_bases
ATGGGCTGGAGCGCTTCACCCGCACCGGACGGTAGCAGGCCGCCACGCAACACGGCGCTCCGTCAGCTCCTGCGCCCGCT
CGAGCCTTACCTCGCGCGGCGCGAGGTGACGGAGCTGGCGGTGAACCGCCCCGGAGAGCTGTGGATTCGCTCGCCGGACG
GCTGGGCGCGTCAGGAGATGCGGGAGCTCACCGCCGAGTACCTCGACGCGCTCGCCACGGCGATGGCCGTCCACAGCGGT
CTCGCGGTGCGGAGCCTCGCGTCGGTGATCCTCCCGGGCGGCGAGCGCGGCCAGCTCGTCCGCGCCCCGGCGTGCGTCGA
CGGAATGGCACCCATGACCATCCGGAAGCACCTCCCTGCGGTCCGGACGCTCGCGGAGCTGGAGCGCGAGGGCACGTTCG
ACCGCGCGCGCGACGTGAGCTTCCATCGTCCTTCCGCGGAGGATGCGCTCCGCGAGTCGGAGCGCAGCGACTCCGGGCGG
CTCGACCCGCTCGACGTCGAGCTCCTGGCCCTCAAGCGCGAGGGCCGGTTCGCCGCGTTCCTGCGGCGAGCGGTGCAGGC
CAGGCGGAACGTCGTGATCGCCGGCAGGACGGGGTCCGGGAAGACGACGCTCACGCGCTCGCTCATCGAGGAGGTGCCGG
CGAGCGAGCGCATCGTGACCATCGAGGACGTGCACGAGCTGGCGCTGCCGAACCACCCGAACCGCGTCCATCTGATGTTC
GGCGGTGGCCCGGGCCGCGTCACTGCGGAGGAATGCCTCGCCGCGTGCATGCGGCTCTCGCCCGACCGGATCTTCCTCGC
CGAGCTGCGCGGGAGCGAGGCGTGGGAGTACGTGCAGAGCCTCAACACCGGGCACCCCGGATCGGTGACGACCACGCACG
CGAACGGCGCGGTGCAGGCGTTCGACCGGATCGCGAGTCTCATAAAGAACAGCGCGACCGGTCGCGGCCTGGAAGTCGCC
GAGATCCGGCGCGTTCTGCACGCGACGCTCGACGTCGTCCTCTTCATGGCAGAGCGGCGCGTCACCGAGGTCTACTTCGA
CCCGCTCCGCGCGAGGGCAGTGCGGTGA

Upstream 100 bases:

>100_bases
TCGATGGAGCCGACCATCAACATCCCGCCGCTGCTCGTAAAGAACCAGGGGGAGCGGGTCGGGATCTTCGTCGCGCGGGA
CCTCGACTTCAGGAGTGTCT

Downstream 100 bases:

>100_bases
GCGGTCGCACGCGGAGTGCCGGACGCACGACCCGTAAAAGACGGCCCAGGGGCCATGCGCTCGGTCGGCAGCGCTGGCAT
AGTAAGGCGTGCCTTGCGAT

Product: P-type DNA transfer ATPase VirB11

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MGWSASPAPDGSRPPRNTALRQLLRPLEPYLARREVTELAVNRPGELWIRSPDGWARQEMRELTAEYLDALATAMAVHSG
LAVRSLASVILPGGERGQLVRAPACVDGMAPMTIRKHLPAVRTLAELEREGTFDRARDVSFHRPSAEDALRESERSDSGR
LDPLDVELLALKREGRFAAFLRRAVQARRNVVIAGRTGSGKTTLTRSLIEEVPASERIVTIEDVHELALPNHPNRVHLMF
GGGPGRVTAEECLAACMRLSPDRIFLAELRGSEAWEYVQSLNTGHPGSVTTTHANGAVQAFDRIASLIKNSATGRGLEVA
EIRRVLHATLDVVLFMAERRVTEVYFDPLRARAVR

Sequences:

>Translated_355_residues
MGWSASPAPDGSRPPRNTALRQLLRPLEPYLARREVTELAVNRPGELWIRSPDGWARQEMRELTAEYLDALATAMAVHSG
LAVRSLASVILPGGERGQLVRAPACVDGMAPMTIRKHLPAVRTLAELEREGTFDRARDVSFHRPSAEDALRESERSDSGR
LDPLDVELLALKREGRFAAFLRRAVQARRNVVIAGRTGSGKTTLTRSLIEEVPASERIVTIEDVHELALPNHPNRVHLMF
GGGPGRVTAEECLAACMRLSPDRIFLAELRGSEAWEYVQSLNTGHPGSVTTTHANGAVQAFDRIASLIKNSATGRGLEVA
EIRRVLHATLDVVLFMAERRVTEVYFDPLRARAVR
>Mature_354_residues
GWSASPAPDGSRPPRNTALRQLLRPLEPYLARREVTELAVNRPGELWIRSPDGWARQEMRELTAEYLDALATAMAVHSGL
AVRSLASVILPGGERGQLVRAPACVDGMAPMTIRKHLPAVRTLAELEREGTFDRARDVSFHRPSAEDALRESERSDSGRL
DPLDVELLALKREGRFAAFLRRAVQARRNVVIAGRTGSGKTTLTRSLIEEVPASERIVTIEDVHELALPNHPNRVHLMFG
GGPGRVTAEECLAACMRLSPDRIFLAELRGSEAWEYVQSLNTGHPGSVTTTHANGAVQAFDRIASLIKNSATGRGLEVAE
IRRVLHATLDVVLFMAERRVTEVYFDPLRARAVR

Specific function: The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice. Virb11 is essential for pathogenesis in mice but is not required for intracellular survival [H]

COG id: COG0630

COG function: function code NU; Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014155
- InterPro:   IPR002078
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E [H]

EC number: NA

Molecular weight: Translated: 39147; Mature: 39016

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGWSASPAPDGSRPPRNTALRQLLRPLEPYLARREVTELAVNRPGELWIRSPDGWARQEM
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHH
RELTAEYLDALATAMAVHSGLAVRSLASVILPGGERGQLVRAPACVDGMAPMTIRKHLPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHCCCCCHHHHHHHHH
VRTLAELEREGTFDRARDVSFHRPSAEDALRESERSDSGRLDPLDVELLALKREGRFAAF
HHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHH
LRRAVQARRNVVIAGRTGSGKTTLTRSLIEEVPASERIVTIEDVHELALPNHPNRVHLMF
HHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCCCCCEEEEEE
GGGPGRVTAEECLAACMRLSPDRIFLAELRGSEAWEYVQSLNTGHPGSVTTTHANGAVQA
CCCCCCCCHHHHHHHHHHCCCCCEEEEHHCCCHHHHHHHHCCCCCCCCEEEECCCHHHHH
FDRIASLIKNSATGRGLEVAEIRRVLHATLDVVLFMAERRVTEVYFDPLRARAVR
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GWSASPAPDGSRPPRNTALRQLLRPLEPYLARREVTELAVNRPGELWIRSPDGWARQEM
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHH
RELTAEYLDALATAMAVHSGLAVRSLASVILPGGERGQLVRAPACVDGMAPMTIRKHLPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHCCCCCHHHHHHHHH
VRTLAELEREGTFDRARDVSFHRPSAEDALRESERSDSGRLDPLDVELLALKREGRFAAF
HHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHH
LRRAVQARRNVVIAGRTGSGKTTLTRSLIEEVPASERIVTIEDVHELALPNHPNRVHLMF
HHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCCCCCEEEEEE
GGGPGRVTAEECLAACMRLSPDRIFLAELRGSEAWEYVQSLNTGHPGSVTTTHANGAVQA
CCCCCCCCHHHHHHHHHHCCCCCEEEEHHCCCHHHHHHHHCCCCCCCCEEEECCCHHHHH
FDRIASLIKNSATGRGLEVAEIRRVLHATLDVVLFMAERRVTEVYFDPLRARAVR
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10940027 [H]